Visible-light-mediated radical oxydifluoromethylation of olefinic amides for the synthesis of CF2H-containing heterocycles.

scientific article published on 28 October 2016

Visible-light-mediated radical oxydifluoromethylation of olefinic amides for the synthesis of CF2H-containing heterocycles. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1039/C6CC07771D
P698PubMed publication ID27790647

P2093author name stringChen Xu
Zhiqiang Wang
Weijun Fu
Mei Zhu
Mao-Ping Song
Xin-Qi Hao
Baoming Ji
Xin Han
P2860cites workA new reagent for direct difluoromethylationQ24599323
Visible light photocatalysis as a greener approach to photochemical synthesisQ28286045
High-throughput catch-and-release synthesis of oxazoline hydroxamates. Structure-activity relationships in novel inhibitors of Escherichia coli LpxC: in vitro enzyme inhibition and antibacterial propertiesQ30885243
Use of fluoroform as a source of difluorocarbene in the synthesis of difluoromethoxy- and difluorothiomethoxyarenesQ33458877
Visible light photoredox catalysis with transition metal complexes: applications in organic synthesisQ34333964
Carbon trifluoromethylation reactions of hydrocarbon derivatives and heteroarenes.Q34460497
Divergent Regioselectivity in Photoredox-Catalyzed Hydrofunctionalization Reactions of Unsaturated Amides and ThioamidesQ34756549
Visible light photoredox catalysis: applications in organic synthesisQ37763554
Introduction of fluorine and fluorine-containing functional groups.Q38123135
Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011).Q38168289
Monofluorination of Organic Compounds: 10 Years of Innovation.Q38411733
Visible light photoredox-controlled reactions of N-radicals and radical ionsQ38721093
Radical C-H functionalization of heteroarenes under electrochemical controlQ41868056
Copper-mediated difluoromethylation of aryl and vinyl iodidesQ42216204
Oxydifluoromethylation of Alkenes by Photoredox Catalysis: Simple Synthesis of CF2H-Containing AlcoholsQ42544898
Synthesis of difluoromethyl ethers with difluoromethyltriflateQ42905296
A designed P1 cysteine mimetic for covalent and non-covalent inhibitors of HCV NS3 protease.Q43036547
Selective difluoromethylation and monofluoromethylation reactionsQ43213764
6-Aryl-1,4-dihydro-benzo[d][1,3]oxazin- 2-ones: a novel class of potent, selective, and orally active nonsteroidal progesterone receptor antagonistsQ44142609
Concise synthesis of acyl migration-blocked 1,1-difluorinated analogues of lysophosphatidic acidQ44158213
The leupyrrins: a structurally unique family of secondary metabolites from the myxobacterium Sorangium cellulosumQ44596824
Copper-mediated difluoromethylation of (hetero)aryl iodides and β-styryl halides with tributyl(difluoromethyl)stannaneQ44779644
Solvent-dependent enantiodivergence in the chlorocyclization of unsaturated carbamatesQ45068574
Enantioselective halocyclization using reagents tailored for chiral anion phase-transfer catalysis.Q46003938
Synthesis of celecoxib analogues possessing a N-difluoromethyl-1,2-dihydropyrid-2-one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.Q46083583
Exploration of Visible-Light Photocatalysis in Heterocycle Synthesis and Functionalization: Reaction Design and Beyond.Q46498330
Dual catalysis sees the light: combining photoredox with organo-, acid, and transition-metal catalysisQ46923730
Copper-Catalyzed Difluoromethylation of Aryl Iodides with (Difluoromethyl)zinc Reagent.Q51239539
Regioselective 2,2,2-Trifluoroethylation of Imidazopyridines by Visible Light Photoredox Catalysis.Q51283692
Visible Light Induced Oxydifluoromethylation of Styrenes with Difluoromethyltriphenylphosphonium Bromide.Q51328680
Photoredox-Catalyzed Bromodifluoromethylation of Alkenes with (Difluoromethyl)triphenylphosphonium Bromide.Q51348448
α-Difluoromethylation on sp(3) Carbon of Nitriles Using Fluoroform and Ruppert-Prakash Reagent.Q51709342
Visible-light-mediated radical aryldifluoroacetylation of alkynes with ethyl bromodifluoroacetate for the synthesis of 3-difluoroacetylated coumarins.Q53271223
Access to Difluoromethylated Arenes by Pd-Catalyzed Reaction of Arylboronic Acids with BromodifluoroacetateQ58803290
P433issue91
P407language of work or nameEnglishQ1860
P921main subjectvisible spectrumQ76299
P1104number of pages4
P304page(s)13413-13416
P577publication date2016-10-28
P1433published inChemical CommunicationsQ426303
P1476titleVisible-light-mediated radical oxydifluoromethylation of olefinic amides for the synthesis of CF2H-containing heterocycles.
P478volume52

Reverse relations

cites work (P2860)
Q48167841Alkyl Esterification of Vinylarenes Enabled by Visible-Light-Induced Decarboxylation.
Q53189569Copper-catalyzed radical cascade oxyalkylation of olefinic amides with simple alkanes: highly efficient access to benzoxazines.
Q52598206Diastereoselective [3 + 2] cycloaddition of 3-ylideneoxindoles with in situ generated CF2HCHN2: syntheses of CF2H-containing spirooxindoles.
Q92022504Late-Stage 18 F-Difluoromethyl Labeling of N-Heteroaromatics with High Molar Activity for PET Imaging
Q42278606Metal-free di- and tri-fluoromethylation of alkenes realized by visible-light-induced perylene photoredox catalysis
Q92928783Synthesis of 3-CF2-Containing Chromones via a Visible-Light-Induced Radical Cascade Reaction of o-Hydroxyaryl Enaminones
Q47587403Visible-light induced di- and trifluoromethylation of N-benzamides with fluorinated sulfones for the synthesis of CF2H/CF3-containing isoquinolinediones
Q42285443Visible-light-induced oxidant and metal-free dehydrogenative cascade trifluoromethylation and oxidation of 1,6-enynes with water
Q50067928Visible-light-mediated direct difluoromethylation of alkynoates: synthesis of 3-difluoromethylated coumarins

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