Effects of intravenous exenatide in type 2 diabetic patients with congestive heart failure: a double-blind, randomised controlled clinical trial of efficacy and safety.

scientific article published on 13 January 2012

Effects of intravenous exenatide in type 2 diabetic patients with congestive heart failure: a double-blind, randomised controlled clinical trial of efficacy and safety. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00125-011-2440-X
P698PubMed publication ID22246377
P5875ResearchGate publication ID221748673

P2093author name stringB Ullman
T Nyström
M Frick
A Sjöholm
A Hedman
D Nathanson
U Löfström
P2860cites workGq/G13 signaling by ET-1 in smooth muscle: MYPT1 phosphorylation via ETA and CPI-17 dephosphorylation via ETB.Q44905666
Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men.Q44924385
Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathyQ45020436
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Endothelial dysfunction induced by triglycerides is not restored by exenatide in rat conduit arteries ex vivo.Q45930780
Pharmacokinetics, pharmacodynamics, tolerability, and safety of exenatide in Japanese patients with type 2 diabetes mellitusQ46220335
Mesenteric vasoconstriction and hindquarters vasodilatation accompany the pressor actions of exendin-4 in conscious ratsQ46750012
Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease.Q53886146
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Diastolic Stiffness of the Failing Diabetic HeartQ58087772
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Interactions of exendin-(9–39) with the effects of glucagon-like peptide-1-(7–36) amide and of exendin-4 on arterial blood pressure and heart rate in ratsQ59616303
Acute hemodynamic and clinical effects of levosimendan in patients with severe heart failure. Study InvestigatorsQ73134596
Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failureQ79437872
Effect of glucagon-like peptide-1 (GLP-1) on glycemic control and left ventricular function in patients undergoing coronary artery bypass graftingQ80843544
Protective effects of GLP-1 analogues exendin-4 and GLP-1(9-36) amide against ischemia-reperfusion injury in rat heartQ81538720
Exendin-4 stimulates proliferation of human coronary artery endothelial cells through eNOS-, PKA- and PI3K/Akt-dependent pathways and requires GLP-1 receptorQ84187312
Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neuronsQ28571689
Cardiac function in mice lacking the glucagon-like peptide-1 receptorQ28586718
GLP-1 receptor stimulation depresses heart rate variability and inhibits neurotransmission to cardiac vagal neurons.Q30497661
Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathyQ33832036
Risk of cardiovascular disease events in patients with type 2 diabetes prescribed the glucagon-like peptide 1 (GLP-1) receptor agonist exenatide twice daily or other glucose-lowering therapies: a retrospective analysis of the LifeLink databaseQ34422144
Glucagon-like peptide-1 increases myocardial glucose uptake via p38alpha MAP kinase-mediated, nitric oxide-dependent mechanisms in conscious dogs with dilated cardiomyopathyQ34786386
Sex and type 2 diabetes: obesity-independent effects on left ventricular substrate metabolism and relaxation in humansQ35858769
Autonomic nervous system-dependent and -independent cardiovascular effects of exendin-4 infusion in conscious ratsQ36735857
Effects of glucagon-like peptide-1, yohimbine, and nitrergic modulation on sympathetic and parasympathetic activity in humansQ36877627
Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivityQ36906298
The potential beneficial role of glucagon-like peptide-1 in endothelial dysfunction and heart failure associated with insulin resistanceQ37269274
Chronic glucagon-like peptide-1 infusion sustains left ventricular systolic function and prolongs survival in the spontaneously hypertensive, heart failure-prone rat.Q37322877
The adrenergic-fatty acid load in heart failureQ37619839
A pilot study to assess whether glucagon-like peptide-1 protects the heart from ischemic dysfunction and attenuates stunning after coronary balloon occlusion in humansQ38490894
Mechanical properties of primary cilia regulate the response to fluid flowQ39749829
Effect of exenatide on heart rate and blood pressure in subjects with type 2 diabetes mellitus: a double-blind, placebo-controlled, randomized pilot studyQ39905736
Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failureQ41267217
Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathwaysQ42165735
Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failureQ43191785
Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteersQ43638669
Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytesQ43726354
Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusionQ44774818
P433issue4
P921main subjectheart failureQ181754
patientQ181600
congestive heart failureQ19000661
P304page(s)926-935
P577publication date2012-01-13
P1433published inDiabetologiaQ5270140
P1476titleEffects of intravenous exenatide in type 2 diabetic patients with congestive heart failure: a double-blind, randomised controlled clinical trial of efficacy and safety.
P478volume55

Reverse relations

cites work (P2860)
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