Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings.

scientific article published on 7 October 2011

Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1742-7843.2011.00792.X
P698PubMed publication ID21902813
P5875ResearchGate publication ID51628627

P50authorJanne BackmanQ51368670
Xiaoqiang XiangQ91330674
Pertti J. NeuvonenQ23039874
Mikko NiemiQ42328966
P2860cites workGenetic variation in the rate-limiting enzyme in cholesterol catabolism (cholesterol 7alpha-hydroxylase) influences the progression of atherosclerosis and risk of new clinical eventsQ45262208
Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans.Q46040113
Polymorphism of the hepatic influx transporter organic anion transporting polypeptide 1B1 is associated with increased cholesterol synthesis rateQ46365149
CYP7A1 promoter polymorphism -203A>C affects bile salt synthesis rate in patients after ileal resectionQ46410501
Genetic polymorphism in cytochrome P450 7A1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer StudyQ46417602
A promoter polymorphism in cholesterol 7alpha-hydroxylase interacts with apolipoprotein E genotype in the LDL-lowering response to atorvastatinQ46504831
Sex differences in the size of bile acid poolsQ47317121
Novel LC-MS/MS method for assay of 7alpha-hydroxy-4-cholesten-3-one in human plasma. Evidence for a significant extrahepatic metabolism.Q51469738
Genetic polymorphism of cholesterol 7alpha-hydroxylase (CYP7A1) and colorectal adenomas: Self Defense Forces Health Study.Q53347067
No significant effect of the SLCO1B1 polymorphism on the pharmacokinetics of ursodeoxycholic acidQ57825120
Mechanism-Based Inactivation of CYP2C8 by Gemfibrozil Occurs Rapidly in HumansQ57825125
Itraconazole, a P-Glycoprotein and CYP3A4 Inhibitor, Markedly Raises the Plasma Concentrations and Enhances the Renin-Inhibiting Effect of AliskirenQ57825127
Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 geneQ33243916
Gender modifies the effect of ursodeoxycholic acid in a randomized controlled trial in colorectal adenoma patientsQ33997826
Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptakeQ34626398
Polymorphisms at cholesterol 7alpha-hydroxylase, apolipoproteins B and E and low density lipoprotein receptor genes in patients with gallbladder stone diseaseQ36308140
Profile of serum bile acids in noncholestatic volunteers: gender-related differences in response to fenofibrateQ36338007
Review article: The function and regulation of proteins involved in bile salt biosynthesis and transportQ37032752
Bile acids and derivatives, their nuclear receptors FXR, PXR and ligands: role in health and disease and their therapeutic potentialQ37184737
Fifty years of advances in bile acid synthesis and metabolismQ37278814
Linkage between cholesterol 7alpha-hydroxylase and high plasma low-density lipoprotein cholesterol concentrationsQ37379392
Common polymorphisms in the CYP7A1 gene do not contribute to variation in rates of bile acid synthesis and plasma LDL cholesterol concentrationQ40382532
Grapefruit juice greatly reduces the plasma concentrations of the OATP2B1 and CYP3A4 substrate aliskirenQ42954978
Gemfibrozil markedly increases the plasma concentrations of montelukast: a previously unrecognized role for CYP2C8 in the metabolism of montelukastQ42997336
Effect of ABCB1 haplotypes on the pharmacokinetics and renin-inhibiting effect of aliskirenQ43055993
Rifampicin reduces the plasma concentrations and the renin-inhibiting effect of aliskirenQ43152152
Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohortQ43209469
High performance liquid chromatography-tandem mass spectrometry for the determination of bile acid concentrations in human plasmaQ43234078
Variable association between genetic variation in the CYP7 gene promoter and plasma lipoproteins in three Canadian populationsQ43546745
Effects of treatment with deoxycholic acid and chenodeoxycholic acid on the hepatic synthesis of cholesterol and bile acids in healthy subjectsQ43601201
Polymorphisms in CYP-7A1, not APOE, influence the change in plasma lipids in response to population dietary change in an 8 year follow-up; results from the Czech MONICA studyQ44480278
Modulating effect of the A-278C promoter polymorphism in the cholesterol 7alpha-hydroxylase gene on serum lipid levels in normolipidaemic and hypertriglyceridaemic individualsQ44969268
P433issue3
P304page(s)245-252
P577publication date2011-10-07
P1433published inBasic and Clinical Pharmacology and ToxicologyQ15724438
P1476titleGender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings.
P478volume110

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cites work (P2860)
Q35993511Age-Related Changes of Plasma Bile Acid Concentrations in Healthy Adults--Results from the Cross-Sectional KarMeN Study
Q35476085CYP7A1 gene polymorphism located in the 5' upstream region modifies the risk of coronary artery disease
Q36414100Determinants of post-prandial plasma bile acid kinetics in human volunteers
Q99604573Identification of Glycochenodeoxycholate 3-O-Glucuronide and Glycodeoxycholate 3-O-Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers
Q36972804Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury.

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