Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity

scientific article published in December 1999

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/16040
P698PubMed publication ID10570489

P50authorClifford J. WoolfQ5132981
Ru-Rong JiQ42386007
P2093author name stringBaba H
Brenner GJ
P2860cites workThe capsaicin receptor: a heat-activated ion channel in the pain pathwayQ24322558
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The MAPK signaling cascadeQ28292599
Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humansQ28320019
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivoQ28609356
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivoQ29615244
Transcriptional and posttranslational plasticity and the generation of inflammatory painQ33679553
Making new connections: role of ERK/MAP kinase signaling in neuronal plasticityQ33685175
Can molecules explain long-term potentiation?Q33686284
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Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation.Q34479232
Activity-dependent neuronal plasticity following tissue injury and inflammationQ35315392
Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivityQ35605155
The somatotopic organization of primary afferent terminals in the superficial laminae of the dorsal horn of the rat spinal cordQ39315531
Parallel signal processing among mammalian MAPKsQ40501929
IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life.Q41082017
Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.Q41464644
MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia.Q42440550
The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and catsQ43674677
Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activityQ46914865
Null Mutations Lacking Substance: Elucidating Pain Mechanisms by Genetic PharmacologyQ47877229
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The MAPK cascade is required for mammalian associative learningQ48240059
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Extracellular signal-regulated kinase (ERK) controls immediate early gene induction on corticostriatal stimulation.Q48367956
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Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulationQ48493712
Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cordQ48617112
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Central nervous system plasticity in the tonic pain response to subcutaneous formalin injectionQ48838894
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Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: relationship to c-fos inductionQ51548076
The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity statesQ52237708
Central and peripheral expression of galanin in response to inflammationQ57990477
Expression of neuropeptide Y and neuropeptide Y (Y1) receptor mRNA in rat spinal cord and dorsal root ganglia following peripheral tissue inflammationQ57990486
Induction of c-fos-like protein in spinal cord neurons following sensory stimulationQ59064203
PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activityQ67542908
Subcutaneous formalin-induced activity of dorsal horn neurones in the rat: differential response to an intrathecal opiate administered pre or post formalinQ69431040
Sensitization of cat dorsal horn neurons to innocuous mechanical stimulation after intradermal injection of capsaicinQ69609149
Formalin induces biphasic activity in C-fibers in the ratQ71324762
Activation of p42 Mitogen‐Activated Protein Kinase by Glutamate Receptor Stimulation in Rat Primary Cortical CulturesQ72103082
NK-1 and NK-3 type tachykinin receptor mRNA expression in the rat spinal cord dorsal horn is increased during adjuvant or formalin-induced nociceptionQ72756940
Evidence for tonic activation of NK-1 receptors during the second phase of the formalin test in the RatQ78025269
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)1114-1119
P577publication date1999-12-01
P1433published inNature NeuroscienceQ1535359
P1476titleNociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity
P478volume2