The sodium channel auxiliary subunits beta1 and beta2 are differentially expressed in the spinal cord of neuropathic rats.

scientific article published in April 1999

The sodium channel auxiliary subunits beta1 and beta2 are differentially expressed in the spinal cord of neuropathic rats. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0306-4522(98)00415-1
P698PubMed publication ID10188942

P2093author name stringFleetwood-Walker SM
Blackburn-Munro G
P2860cites workStructure and chromosomal localization of the beta2 subunit of the human brain sodium channelQ24311583
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Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neuronsQ28569751
A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neuronsQ28570486
Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motifQ28579493
VIP and noradrenaline act synergistically to increase cyclic AMP in cerebral cortexQ34055335
Structure and function of voltage-gated ion channelsQ34296742
Na+ channel immunolocalization in peripheral mammalian axons and changes following nerve injury and neuroma formationQ34306077
A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.Q34554719
Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomyQ37019966
Down-regulation of transcripts for Na channel alpha-SNS in spinal sensory neurons following axotomyQ37057545
Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGFQ38325531
Downregulation of Na+ channel mRNA in olfactory bulb tufted cells following deafferentationQ38347573
Cell-specific differential expression of Na(+)-channel beta 1-subunit mRNA in the olfactory system during postnatal development and after denervationQ38362839
Substance P: Depletion in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neuronsQ40229378
Messenger plasticity in primary sensory neurons following axotomy and its functional implicationsQ40387628
Regulation of Na+ channel beta 1 and beta 2 subunit mRNA levels in cultured rat astrocytesQ41080056
The beta 1 sodium channel subunit modifies the interactions of neurotoxins and local anesthetics with the rat brain IIA alpha sodium channel in isolated membranes but not in intact cellsQ41200352
Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell lineQ41368759
The tenascin gene family in axon growth and guidanceQ41606035
Efficient expression of rat brain type IIA Na+ channel α subunits in a somatic cell lineQ41651477
Differential influence of nerve growth factor on neuropeptide expression in vivo: a novel role in peptide suppression in adult sensory neurons.Q41664947
The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neuronsQ42454315
Functional analysis of the rat I sodium channel in xenopus oocytes.Q42545515
Effect of lamotrigine in the acute and chronic hyperalgesia induced by PGE2 and in the chronic hyperalgesia in rats with streptozotocin-induced diabetesQ42557259
Time course of degenerative and regenerative changes in the dorsal horn in a rat model of peripheral neuropathyQ45016556
Substance P induced hydrolysis of inositol phospholipids in guinea-pig ileum and rat hypothalamusQ46669265
Distinct regulation of sodium channel types I, II and III following nerve transectionQ48167535
Signs of neuropathic pain depend on signals from injured nerve fibers in a rat modelQ48300438
Expression of functional sodium channels from cloned cDNA.Q48312078
Vasoactive intestinal polypeptide (VIP) increases in the spinal cord after peripheral axotomy of the sciatic nerve originate from primary afferent neuronsQ48353120
Distribution of I, II and III subtypes of voltage-sensitive Na+ channel mRNA in the rat brainQ48369705
Unilateral nerve injury down-regulates mRNA for Na+ channel SCN10A bilaterally in rat dorsal root gangliaQ48550844
Down-regulation of voltage-dependent sodium channels coincides with a low expression of alphabeta1 subunit complexesQ48564818
QX-314 inhibits ectopic nerve activity associated with neuropathic painQ48584770
Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system.Q48747956
Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAsQ48826387
Experimental and modeling study of Na+ current heterogeneity in rat nodose neurons and its impact on neuronal discharge.Q51531035
Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury.Q51542388
Differential properties of tetrodotoxin-sensitive and tetrodotoxin- resistant sodium channels in rat dorsal root ganglion neuronsQ51690509
Ionic currents in the somatic membrane of rat dorsal root ganglion neurons—I. Sodium currentsQ51871000
Reorganization of central terminals of myelinated primary afferents in the rat dorsal horn following peripheral axotomy.Q52206001
Peripheral nerve injury triggers central sprouting of myelinated afferentsQ52233221
Loss of dorsal root ganglion cells concomitant with dorsal root axon sprouting following segmental nerve lesionsQ57503452
Lamotrigine (Lamictal) in refractory trigeminal neuralgia: results from a double-blind placebo controlled crossover trialQ57984131
Reciprocal regulation of tachykinin- and vasoactive intestinal peptide-gene expression in rat sensory neurones following cut and crush injuryQ69585745
Expression of sodium channel alpha- and beta-subunits in the nervous system of the myelin-deficient ratQ71587528
Sympathetic sprouting in the dorsal root ganglia of the injured peripheral nerve in a rat neuropathic pain modelQ71851438
Differential up-regulation of sodium channel α- and β1-subunit mRNAs in cultured embryonic DRG neurons following exposure to NGFQ71873829
Hyperexcitability at sites of nerve injury depends on voltage-sensitive Na+ channelsQ72816452
The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic painQ73328419
The effects of Na+ channel blockers on somatosensory processing by rat dorsal horn neuronesQ73430444
Lamotrigine control of central painQ73574713
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)153-164
P577publication date1999-04-01
P1433published inNeuroscienceQ15708571
P1476titleThe sodium channel auxiliary subunits beta1 and beta2 are differentially expressed in the spinal cord of neuropathic rats.
P478volume90

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cites work (P2860)
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Q50721637beta3, a novel auxiliary subunit for the voltage-gated sodium channel, is expressed preferentially in sensory neurons and is upregulated in the chronic constriction injury model of neuropathic pain.