Synergistic cytotoxicity of the poly (ADP-ribose) polymerase inhibitor ABT-888 and temozolomide in dual-drug targeted magnetic nanoparticles.

scientific article published on 3 June 2014

Synergistic cytotoxicity of the poly (ADP-ribose) polymerase inhibitor ABT-888 and temozolomide in dual-drug targeted magnetic nanoparticles. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/LIV.12586
P698PubMed publication ID24821649
P5875ResearchGate publication ID262231405

P50authorÁngeles O Angela Ruiz-ExtremeraQ71720473
Julián López-Viota GallardoQ79286646
P2093author name stringJavier Salmerón
Laura Sanjuán-Nuñez
Rosa Quiles-Perez
Paloma Muñoz-de-Rueda
José A Muñoz-Gámez
Ángel Carazo
Ángel Delgado
Andrés Barrientos
P2860cites workTargeting poly(ADP-ribose) polymerase activity for cancer therapyQ34204660
Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damageQ34576873
CMCTS stabilized Fe3O4 particles with extremely low toxicity as highly efficient near-infrared photothermal agents for in vivo tumor ablationQ34843802
Chemopotentiation by PARP inhibitors in cancer therapy.Q36136079
Role of the peroxynitrite-poly (ADP-ribose) polymerase pathway in the pathogenesis of liver injuryQ36570222
Nanoscale drug delivery systems for enhanced drug penetration into solid tumors: current progress and opportunitiesQ36803827
Modulation of transcription by PARP-1: consequences in carcinogenesis and inflammation.Q36822642
Therapeutic applications of PARP inhibitors: anticancer therapy and beyondQ36853236
Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriersQ37178442
The safety of the temozolomide in patients with malignant glioma.Q37239375
PARP inhibitors: new partners in the therapy of cancer and inflammatory diseases.Q37442057
Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosisQ37684726
A novel approach to overcome temozolomide resistance in glioma and melanoma: Inactivation of MGMT by gene therapyQ37844192
Nanomedicine for targeted cancer therapy: towards the overcoming of drug resistance.Q37844303
Promising approaches in using magnetic nanoparticles in oncologyQ37919101
Theranostic nanomedicine for cancer detection and treatmentQ38199787
Functionalized magnetic nanoparticles as vehicles for the delivery of the antitumor drug gemcitabine to tumor cells. Physicochemical in vitro evaluation.Q39130328
Nanoengineering of doxorubicin delivery systems with functionalized maghemite nanoparticlesQ39136391
Inhibition of poly (ADP-ribose) polymerase-1 enhances doxorubicin activity against liver cancer cellsQ39629347
Doxorubicin-loaded solid lipid nanoparticles to overcome multidrug resistance in cancer therapyQ39754343
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activationQ39773986
In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016.Q39894612
Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expressionQ42831020
ABT-888 confers broad in vivo activity in combination with temozolomide in diverse tumorsQ43236659
The properties of tumor-initiating cells from a hepatocellular carcinoma patient's primary and recurrent tumor.Q43246238
Discovery of the Poly(ADP-ribose) polymerase (PARP) inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the treatment of cancerQ46163448
Solid lipid nanoparticles of temozolomide: potential reduction of cardial and nephric toxicityQ46768039
Poly(ADP-ribose) polymerase-1 inhibition increases expression of heat shock proteins and attenuates heat stroke-induced liver injuryQ46842550
Nanotechnology: Carrying drugsQ48317547
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling.Q52087746
P433issue4
P921main subjectcytotoxicityQ246181
magnetite nanoparticleQ3870166
magnetic nanoparticleQ117817683
P304page(s)1430-1441
P577publication date2014-06-03
P1433published inLiver InternationalQ15765078
P1476titleSynergistic cytotoxicity of the poly (ADP-ribose) polymerase inhibitor ABT-888 and temozolomide in dual-drug targeted magnetic nanoparticles
P478volume35

Reverse relations

cites work (P2860)
Q40218092Comprehensive multiplatform biomarker analysis of 350 hepatocellular carcinomas identifies potential novel therapeutic options
Q33828196Inhibitors of PARP-1 exert inhibitory effects on the biological characteristics of hepatocellular carcinoma cells in vitro
Q26823523Nanoparticles for targeted delivery of therapeutics and small interfering RNAs in hepatocellular carcinoma
Q57144042PARP1 activation increases expression of modified tumor suppressors and pathways underlying development of aggressive hepatoblastoma
Q37372483The PARP inhibitor ABT-888 potentiates dacarbazine-induced cell death in carcinoids

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