Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis.

scientific article published on 29 March 2009

Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NM.1945
P698PubMed publication ID19330010
P5875ResearchGate publication ID24242480

P50authorThomas M StulnigQ44539480
Josef S SmolenQ66753681
P2093author name stringOskar Hoffmann
Reinhold G Erben
Matthias Mack
Thomas Pap
Nikolaus B Binder
Birgit Niederreiter
Kurt Redlich
Richard Stange
P2860cites workMolecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tailsQ24310185
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
RANK is essential for osteoclast and lymph node developmentQ24598872
Bone resorption by osteoclastsQ28145169
CCL9/MIP-1gamma and its receptor CCR1 are the major chemokine ligand/receptor species expressed by osteoclastsQ28210471
MCP-1 is induced by receptor activator of nuclear factor-{kappa}B ligand, promotes human osteoclast fusion, and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formationQ28236005
Denosumab in postmenopausal women with low bone mineral densityQ28298728
SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclastsQ28510858
Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout miceQ28585385
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature CommitteeQ29616160
A rapid single-laser flow cytometric method for discrimination of early apoptotic cells in a heterogenous cell population.Q30656299
OsteopetrosisQ34380528
Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptorsQ34520133
Estrogen deficiency and bone loss: an inflammatory taleQ34576622
Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritisQ35083436
Differentiation and function of osteoclastsQ35113943
Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sitesQ35664094
Mechanisms of action of antiresorptive therapies of postmenopausal osteoporosis.Q35755088
CD44 is a determinant of inflammatory bone lossQ36403383
Direct and indirect estrogen actions on osteoblasts and osteoclastsQ36532519
Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection.Q36661058
Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alphaQ37271202
Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclastsQ40862968
IL-1 mediates TNF-induced osteoclastogenesisQ40909592
Role of cytokines in bone resorptionQ40957399
Effect of hormone replacement therapy on nitric oxide bioactivity and monocyte chemoattractant protein-1 levelsQ43787126
Monocyte chemoattractant protein-1 induces proliferation and interleukin-6 production in human smooth muscle cells by differential activation of nuclear factor-kappaB and activator protein-1.Q44030294
Estrogen decreases expression of chemokine receptors, and suppresses chemokine bioactivity in murine monocytesQ44729731
Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic miceQ44733643
Association of a polymorphism of the CC chemokine receptor-2 gene with bone mineral densityQ45887159
Induction of chemokines and chemokine receptors CCR2b and CCR4 in authentic human osteoclasts differentiated with RANKL and osteoclast like cells differentiated by MCP-1 and RANTES.Q46741114
The expression of CCL2 by T lymphocytes of mammary tumor bearers: role of tumor-derived factorsQ46769001
Cytokines, hematopoiesis, osteoclastogenesis, and estrogensQ68182334
Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient ratsQ68267253
Evaluation of serum osteocalcin as an index of altered bone metabolismQ70144072
Biochemical markers of bone turnover in Paget's diseaseQ72780083
Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myelomaQ73971509
Sex steroids and boneQ74124341
Chemokine receptorsQ74481121
Regulation of monocyte chemotactic protein-1 expression in human endometrial stromal cells by estrogen and progesteroneQ77905995
Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myelomaQ81248007
MCP-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, NFATc1, and calcitonin receptor-positive but require receptor activator of NFkappaB ligand for bone resorptionQ81464707
Expression and characterization of the chemokine receptors CCR2 and CCR5 in miceQ95721029
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectosteoporosisQ165328
P304page(s)417-424
P577publication date2009-03-29
P1433published inNature MedicineQ1633234
P1476titleEstrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis.
P478volume15