Wnt signaling regulates atrioventricular canal formation upstream of BMP and Tbx2.

scientific article published on 28 April 2011

Wnt signaling regulates atrioventricular canal formation upstream of BMP and Tbx2. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/BDRA.20804
P698PubMed publication ID21567896
P5875ResearchGate publication ID51122572

P50authorVincent M. ChristoffelsQ70803769
Gilbert WeidingerQ38590941
Jeroen BakkersQ39512692
P2093author name stringManon C Verhoeven
Christa Haase
P2860cites workMaternally supplied Smad5 is required for ventral specification in zebrafish embryos prior to zygotic Bmp signalingQ42685381
Mesodermal Wnt2b signalling positively regulates liver specification.Q45995605
The wingless signaling pathway is directly involved in Drosophila heart developmentQ47072326
The Wnt/beta-catenin pathway regulates cardiac valve formationQ47073676
Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2.Q52162551
Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2Q24294772
T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambersQ24320013
Dominant-negative ALK2 allele associates with congenital heart defectsQ24337521
Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formationQ24675337
Functional modulation of cardiac form through regionally confined cell shape changesQ27334821
Inhibition of Wnt activity induces heart formation from posterior mesodermQ28346509
Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterningQ28504579
Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart developmentQ28508308
Canonical Wnt signaling functions in second heart field to promote right ventricular growthQ28588651
Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canalQ28590185
The incidence of congenital heart diseaseQ29614195
Wnt antagonism initiates cardiogenesis in Xenopus laevisQ33931613
Dually inducible TetON systems for tissue-specific conditional gene expression in zebrafish.Q34358914
APC, signal transduction and genetic instability in colorectal cancerQ34568154
Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factorsQ34571556
Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cellsQ35808417
Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitorsQ35865003
Architectural plan for the heart: early patterning and delineation of the chambers and the nodes.Q35982225
Wnt signal transduction and the formation of the myocardiumQ36430885
The role of Wnt signalling in cardiac development and tissue remodelling in the mature heartQ36543886
T-box factors determine cardiac design.Q36767576
Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewalQ37080793
Foxn4 directly regulates tbx2b expression and atrioventricular canal formationQ38292640
P433issue6
P304page(s)435-440
P577publication date2011-04-28
P1433published inBirth Defects Research Part A: Clinical and Molecular TeratologyQ15724446
P1476titleWnt signaling regulates atrioventricular canal formation upstream of BMP and Tbx2
P478volume91

Reverse relations

cites work (P2860)
Q42027007Bmp signaling exerts opposite effects on cardiac differentiation
Q27339339Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties.
Q42709337Cardiotoxicity of mycotoxin citrinin and involvement of microRNA-138 in zebrafish embryos
Q35690311Characteristic expression of MSX1, MSX2, TBX2 and ENTPD1 in dental pulp cells
Q43184172Coins of the realm in atrioventricular junction development
Q45262771Development and Function of the Cardiac Conduction System in Health and Disease
Q35111199Effects of miR-19b knockdown on the cardiac differentiation of P19 mouse embryonic carcinoma cells
Q34601524Effects of miR-19b overexpression on proliferation, differentiation, apoptosis and Wnt/β-catenin signaling pathway in P19 cell model of cardiac differentiation in vitro
Q26830155Endocardial and epicardial epithelial to mesenchymal transitions in heart development and disease
Q39416430GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development.
Q47073588Id4 functions downstream of Bmp signaling to restrict TCF function in endocardial cells during atrioventricular valve development.
Q36227102Identifying the evolutionary building blocks of the cardiac conduction system.
Q57030143Notch and interacting signalling pathways in cardiac development, disease, and regeneration
Q48172096On the Evolution of the Cardiac Pacemaker
Q48106167Spatially resolved RNA-sequencing of the embryonic heart identifies a role for Wnt/β-catenin signaling in autonomic control of heart rate.
Q39676931Strategies for analyzing cardiac phenotypes in the zebrafish embryo
Q61816624TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis
Q30583884The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis
Q26770904The formation and function of the cardiac conduction system
Q35208712The novel transmembrane protein Tmem2 is essential for coordination of myocardial and endocardial morphogenesis.
Q92836594Tmem2 restricts atrioventricular canal differentiation by regulating degradation of hyaluronic acid
Q89014504Transcriptional regulation of the cardiac conduction system
Q37878169Zebrafish as a model to study cardiac development and human cardiac disease
Q38019209Zebrafish models in cardiac development and congenital heart birth defects
Q93170062pouC Regulates Expression of bmp4 During Atrioventricular Canal Formation in Zebrafish