DNA methyltransferase 1

mammalian protein found in Homo sapiens

Wikidata entity: Q5205796



P682 biological process ... Q411391 (regulation of gene expression) regulation of gene expression
P682 biological process ... Q518328 (methylation) methylation
P682 biological process ... Q874745 (DNA methylation) DNA methylation
P682 biological process ... Q14599352 (Ras protein signal transduction) Ras protein signal transduction
P682 biological process ... Q14633878 (negative regulation of transcription by RNA polymerase II) negative regulation of transcription by RNA polymerase II
P682 biological process ... Q14633883 (regulation of transcription, DNA-templated) regulation of transcription, DNA-templated
P682 biological process ... Q14633893 (positive regulation of gene expression) positive regulation of gene expression
P682 biological process ... Q14633919 (negative regulation of transcription, DNA-templated) negative regulation of transcription, DNA-templated
P682 biological process ... Q14763010 (transcription, DNA-templated) transcription, DNA-templated
P682 biological process ... Q14818120 (regulation of cell population proliferation) regulation of cell population proliferation
P682 biological process ... Q14819859 (negative regulation of gene expression) negative regulation of gene expression
P682 biological process ... Q21102107 (DNA methylation involved in embryo development) DNA methylation involved in embryo development
P682 biological process ... Q22260616 (positive regulation of DNA methylation-dependent heterochromatin assembly) positive regulation of DNA methylation-dependent heterochromatin assembly
P682 biological process ... Q22260812 (DNA methylation on cytosine) DNA methylation on cytosine
P682 biological process ... Q22305572 (positive regulation of vascular associated smooth muscle cell proliferation) positive regulation of vascular associated smooth muscle cell proliferation
P682 biological process ... Q14860460 (positive regulation of histone H3-K4 methylation) positive regulation of histone H3-K4 methylation
P682 biological process ... Q14860461 (negative regulation of histone H3-K9 methylation) negative regulation of histone H3-K9 methylation
P682 biological process ... Q14881723 (cellular response to amino acid stimulus) cellular response to amino acid stimulus
P682 biological process ... Q14907997 (maintenance of DNA methylation) maintenance of DNA methylation
P682 biological process ... Q14908002 (DNA methylation on cytosine within a CG sequence) DNA methylation on cytosine within a CG sequence
P682 biological process ... Q14908004 (C-5 methylation of cytosine) C-5 methylation of cytosine
P682 biological process ... Q15313471 (negative regulation of gene expression, epigenetic) negative regulation of gene expression, epigenetic
P682 biological process ... Q15322272 (chromatin organization) chromatin organization
P682 biological process ... Q27118373 (negative regulation of vascular associated smooth muscle cell apoptotic process) negative regulation of vascular associated smooth muscle cell apoptotic process
P682 biological process ... Q29572950 (negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching) negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q837783 (heterochromatin) heterochromatin
P681 cell component ... Q2289104 (replication fork) replication fork
P681 cell component ... Q14817956 (nucleoplasm) nucleoplasm
P681 cell component ... Q14907994 (pericentric heterochromatin) pericentric heterochromatin
P702 encoded by ... Q14907998 (DNMT1) DNMT1
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P692 Gene Atlas image CommonsMedia http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20DNMT1%20201697%20s%20at%20fs.png ???
P527 has part(s) ... Q24720904 (DNA methylase, C-5 cytosine-specific, active site) DNA methylase, C-5 cytosine-specific, active site
P527 has part(s) ... Q24721201 (Zinc finger, CXXC-type) Zinc finger, CXXC-type
P527 has part(s) ... Q24722518 (DMAP1-binding domain) DMAP1-binding domain
P527 has part(s) ... Q24769975 (Bromo adjacent homology (BAH) domain) Bromo adjacent homology (BAH) domain
P527 has part(s) ... Q24777645 (DNA methylase, C-5 cytosine-specific, conserved site) DNA methylase, C-5 cytosine-specific, conserved site
P527 has part(s) ... Q24786986 (DNA (cytosine-5)-methyltransferase 1, replication foci domain) DNA (cytosine-5)-methyltransferase 1, replication foci domain
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q13667380 (metal ion binding) metal ion binding
P680 molecular function ... Q14330639 (RNA binding) RNA binding
P680 molecular function ... Q14633858 (DNA binding) DNA binding
P680 molecular function ... Q14633865 (zinc ion binding) zinc ion binding
P680 molecular function ... Q14817976 (chromatin binding) chromatin binding
P680 molecular function ... Q14840131 (transferase activity) transferase activity
P680 molecular function ... Q22312996 (promoter-specific chromatin binding) promoter-specific chromatin binding
P680 molecular function ... Q14863658 (methyltransferase activity) methyltransferase activity
P680 molecular function ... Q14864645 (DNA-binding transcription factor activity, RNA polymerase II-specific) DNA-binding transcription factor activity, RNA polymerase II-specific
P680 molecular function ... Q14905544 (methyl-CpG binding) methyl-CpG binding
P680 molecular function ... Q14907995 (DNA (cytosine-5-)-methyltransferase activity) DNA (cytosine-5-)-methyltransferase activity
P680 molecular function ... Q14907996 (DNA-methyltransferase activity) DNA-methyltransferase activity
P361 part of ... Q24769006 (DNA (cytosine-5)-methyltransferase 1-like) DNA (cytosine-5)-methyltransferase 1-like
P361 part of ... Q24780258 (S-adenosyl-L-methionine-dependent methyltransferase) S-adenosyl-L-methionine-dependent methyltransferase
P361 part of ... Q83133237 (Zinc finger, CXXC-type, protein family) Zinc finger, CXXC-type, protein family
P361 part of ... Q83133848 (DMAP1-binding domain, protein family) DMAP1-binding domain, protein family
P361 part of ... Q83139702 (Bromo adjacent homology (BAH) domain, protein family) Bromo adjacent homology (BAH) domain, protein family
P361 part of ... Q83166010 (DNA (cytosine-5)-methyltransferase 1, replication foci domain, protein family) DNA (cytosine-5)-methyltransferase 1, replication foci domain, protein family
P361 part of ... Q95352059 (DNA methylase, C-5 cytosine-specific, active site, protein family) DNA methylase, C-5 cytosine-specific, active site, protein family
P361 part of ... Q95352838 (DNA methylase, C-5 cytosine-specific, conserved site, protein family) DNA methylase, C-5 cytosine-specific, conserved site, protein family
P129 physically interacts with ... Q1181878 (decitabine) decitabine

External Ids
P705Ensembl protein IDENSP00000468062
P705Ensembl protein IDENSP00000352516
P705Ensembl protein IDENSP00000465993
P705Ensembl protein IDENSP00000467260
P705Ensembl protein IDENSP00000345739
P705Ensembl protein IDENSP00000467125
P705Ensembl protein IDENSP00000466657
P705Ensembl protein IDENSP00000468359
P705Ensembl protein IDENSP00000467050
P705Ensembl protein IDENSP00000465555
P705Ensembl protein IDENSP00000464958
P705Ensembl protein IDENSP00000465223
P486MeSH descriptor IDD000076123
P672MeSH tree codeD08.811.913.555.500.350.100.500.500
P672MeSH tree codeD12.776.157.687.313
P672MeSH tree codeD12.776.660.720.313
P638PDB structure ID3SWR
P638PDB structure ID4WXX
P638PDB structure ID4YOC
P638PDB structure ID3EPZ
P638PDB structure ID3PTA
P637RefSeq protein IDNP_001124295
P637RefSeq protein IDNP_001305659
P637RefSeq protein IDNP_001305660
P637RefSeq protein IDNP_001370
P2892UMLS CUIC1621352
P352UniProt protein IDP26358

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