A sudden decline in active membrane-bound TGF-beta impairs both T regulatory cell function and protection against autoimmune diabetes.

scientific article published in December 2004

A sudden decline in active membrane-bound TGF-beta impairs both T regulatory cell function and protection against autoimmune diabetes. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4049/JIMMUNOL.173.12.7308
P698PubMed publication ID15585854
P5875ResearchGate publication ID8141886

P2093author name stringRohit Divekar
Ping Yu
Hyun-Hee Lee
J Jeremiah Bell
Habib Zaghouani
Renu Jain
Randal K Gregg
Scott J Schoenleber
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectcell functionQ95674809
P304page(s)7308-7316
P577publication date2004-12-01
P1433published inJournal of ImmunologyQ3521441
P1476titleA sudden decline in active membrane-bound TGF-beta impairs both T regulatory cell function and protection against autoimmune diabetes.
P478volume173

Reverse relations

cites work (P2860)
Q33384634APC activation restores functional CD4(+)CD25(+) regulatory T cells in NOD mice that can prevent diabetes development
Q33661871Activation of aryl hydrocarbon receptor by TCDD prevents diabetes in NOD mice and increases Foxp3+ T cells in pancreatic lymph nodes
Q42578734Antigen-Specific Immune Modulation Targets mTORC1 Function To Drive Chemokine Receptor-Mediated T Cell Tolerance.
Q36920276Antigen-specific effector CD4 T lymphocytes school lamina propria dendritic cells to transfer innate tolerance
Q35762883Antigen-specific therapeutic approaches in Type 1 diabetes
Q38184646Antigen-specific therapy against type 1 diabetes: mechanisms and perspectives
Q38771022Apportioning Blame: Autoreactive CD4+ and CD8+ T Cells in Type 1 Diabetes
Q36228247B cell-deficient NOD.H-2h4 mice have CD4+CD25+ T regulatory cells that inhibit the development of spontaneous autoimmune thyroiditis
Q50322131Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice
Q53560161Diabetes in non-obese diabetic mice is not associated with quantitative changes in CD4+ CD25+ Foxp3+ regulatory T cells.
Q39928054Disturbances in some gene expression in T regulatory cells separated from children with metabolic syndrome.
Q44370377Downregulation of TGF-βRII in T effector cells leads to increased resistance to TGF-β-mediated suppression of autoimmune responses in type I diabetes
Q37359000Dysrulation of T cell peripheral tolerance in type 1 diabetes
Q33955180Effector and naturally occurring regulatory T cells display no abnormalities in activation induced cell death in NOD mice
Q36715704Feline glycoprotein A repetitions predominant anchors transforming growth factor beta on the surface of activated CD4(+)CD25(+) regulatory T cells and mediates AIDS lentivirus-induced T cell immunodeficiency
Q39752246FoxP3+RORgammat+ T helper intermediates display suppressive function against autoimmune diabetes
Q26752197GARP: a surface molecule of regulatory T cells that is involved in the regulatory function and TGF-β releasing
Q35659179Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β.
Q33237082Highly sensitive and specific bioassay for measuring bioactive TGF-beta
Q36881697Host resistance and immune responses in advanced age.
Q34166274Immunomodulation of antigen presenting cells promotes natural regulatory T cells that prevent autoimmune diabetes in NOD mice
Q37017265Immunosupportive therapies in aging
Q33770196Induced Regulatory T Cells Superimpose Their Suppressive Capacity with Effector T Cells in Lymph Nodes via Antigen-Specific S1p1-Dependent Egress Blockage
Q81150553Infiltration of forkhead box P3-expressing cells in small intestinal mucosa in coeliac disease but not in type 1 diabetes
Q51673568Inhibition of type 1 diabetes in filaria-infected non-obese diabetic mice is associated with a T helper type 2 shift and induction of FoxP3+ regulatory T cells.
Q36446935Innocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production
Q38691482Mechanisms of autoimmunity in the non-obese diabetic mouse: effector/regulatory cell equilibrium during peak inflammation
Q36109325Mechanisms underlying antigen-specific tolerance of stable and convertible Th17 cells during suppression of autoimmune diabetes
Q37737987Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease
Q38966071Neutralization Versus Reinforcement of Proinflammatory Cytokines to Arrest Autoimmunity in Type 1 Diabetes
Q37208578Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells
Q54309935Notch activation on effector T cells increases their sensitivity to Treg cell-mediated suppression through upregulation of TGF-βRII expression.
Q38655427Novel technologies to engineer graft for tolerance induction
Q48228458On the Role IL-4/IL-13 Heteroreceptor Plays in Regulation of Type 1 Diabetes
Q35035427Phenotypic modulation of auto-reactive cells by insertion of tolerogenic molecules via MSC-derived exosomes
Q34178740Pre-clinical assessment of autologous DC-based therapy in ovarian cancer patients with progressive disease
Q83168646Pro-apoptotic DNA vaccination ameliorates new onset of autoimmune diabetes in NOD mice and induces foxp3+ regulatory T cells in vitro
Q56901937Protective regulatory T cell generation in autoimmune diabetes by DNA covaccination with islet antigens and a selective CTLA-4 ligand
Q37030992Recovery from overt type 1 diabetes ensues when immune tolerance and β-cell formation are coupled with regeneration of endothelial cells in the pancreatic islets
Q37618585Regulation of type 1 diabetes, tuberculosis, and asthma by parasites
Q36969926Regulatory T cells and toll-like receptors: regulating the regulators
Q43513695Regulatory T-cell therapy: is it ready for the clinic?
Q35610749Segregated regulatory CD39+CD4+ T cell function: TGF-β-producing Foxp3- and IL-10-producing Foxp3+ cells are interdependent for protection against collagen-induced arthritis
Q51567175Semi-mature DC are immunogenic and not tolerogenic when inoculated at a high dose in collagen-induced arthritis mice.
Q28585423Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens
Q87409683Stable activity of diabetogenic cells with age in NOD mice: dynamics of reconstitution and adoptive diabetes transfer in immunocompromised mice
Q36251293T cell tolerance induced by therapeutic antibodies
Q36989149TGFbeta1 and Treg cells: alliance for tolerance
Q53357495Targeting of IL-2 receptor with a caspase fusion protein disrupts autoimmunity in prediabetic and diabetic NOD mice.
Q36421334The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(+) regulatory T cells in the nonobese diabetic type 1 diabetes model.
Q35569913The role of regulatory T cell defects in type I diabetes and the potential of these cells for therapy
Q36557587Transforming growth factor-beta: an important role in CD4+CD25+ regulatory T cells and immune tolerance
Q36434147Transforming growth factor-beta: recent advances on its role in immune tolerance
Q37220376Vaccination with photodynamic therapy-treated macrophages induces highly suppressive T-regulatory cells
Q41888326Vasoactive intestinal peptide generates human tolerogenic dendritic cells that induce CD4 and CD8 regulatory T cells.
Q35849658Vasoactive intestinal peptide induces regulatory dendritic cells that prevent acute graft-versus-host disease while maintaining the graft-versus-tumor response

Search more.