Overexpression of transcription factor AP-2alpha suppresses mammary gland growth and morphogenesis.

scientific article published in April 2003

Overexpression of transcription factor AP-2alpha suppresses mammary gland growth and morphogenesis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0012-1606(02)00119-7
P698PubMed publication ID12654297

P2093author name stringZhang J
Huang J
Williams T
Brewer S
P2860cites workHypercalcemia, parathyroid hormone-related protein expression and human T-cell leukemia virus infectionQ40563654
Think globally, act locally: the making of a mouse mammary gland.Q41705141
Transforming growth factor-alpha-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation.Q41916797
Characterization of the promoter of the gene encoding human tissue inhibitor of metalloproteinases-2 (TIMP-2).Q42801510
Expression of dominant-negative ErbB2 in the mammary gland of transgenic mice reveals a role in lobuloalveolar development and lactationQ42814150
Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP.Q43554604
AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expressionQ45345486
Stat5a is mandatory for adult mammary gland development and lactogenesis.Q48055024
Mechanisms identified in the transcriptional control of epithelial gene expressionQ48067012
Comparative analysis of AP-2 alpha and AP-2 beta gene expression during murine embryogenesis.Q52197891
N-ras oncogene causes AP-2 transcriptional self-interference, which leads to transformation.Q53472029
AP-2.2, a novel gene related to AP-2, is expressed in the forebrain, limbs and face during mouse embryogenesisQ62818027
Dramatic heterogeneity of transgene expression in the mammary gland of lactating mice: a model system to study the synthetic activity of mammary epithelial cellsQ72191595
Identification of ERF-1 as a member of the AP2 transcription factor familyQ24314887
Transcription factor gene AP-2 gamma essential for early murine developmentQ24537286
Transcriptional activation by Myc is under negative control by the transcription factor AP-2Q24568331
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Arrest of spermatogenesis and defective breast development in mice lacking A-mybQ28235377
Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteinsQ28266897
Analysis of the DNA-binding and activation properties of the human transcription factor AP-2Q28271397
Impaired mammary gland development in Cyl-1(-/-) mice during pregnancy and lactation is epithelial cell autonomousQ28508152
Cloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation propertiesQ28510687
Transcription factor AP-2 essential for cranial closure and craniofacial developmentQ28513302
Requirement for AP-2alpha in cardiac outflow tract morphogenesisQ28584763
AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric miceQ28586197
AP-2alpha transcription factor is required for early morphogenesis of the lens vesicleQ28587027
Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2betaQ28591284
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responsesQ28592023
ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactationQ28594099
Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2Q28594321
Simplified mammalian DNA isolation procedureQ29618648
Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesisQ33515610
Programmed cell death in the terminal endbudQ33699455
Role of AP-2 in tumor growth and metastasis of human melanomaQ33865634
Transcriptional regulation of type I receptor tyrosine kinases in the mammary glandQ33959337
Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation.Q34050002
Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigenQ34163571
Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elementsQ34164797
The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinomaQ34725896
A paracrine role for the epithelial progesterone receptor in mammary gland developmentQ36064196
Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1.Q36757191
Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP-2.Q37686223
Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancerQ38466179
SELEX and missing phosphate contact analyses reveal flexibility within the AP-2[alpha] protein: DNA binding complexQ39728282
AP2alpha and AP2gamma: a comparison of binding site specificity and trans-activation of the estrogen receptor promoter and single site promoter constructs.Q39729287
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmorphogenesisQ815547
overexpressionQ61643320
P304page(s)127-145
P577publication date2003-04-01
P1433published inDevelopmental BiologyQ3025402
P1476titleOverexpression of transcription factor AP-2alpha suppresses mammary gland growth and morphogenesis.
P478volume256