Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation.

scientific article published in January 1999

Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.ONC.1202387
P698PubMed publication ID10023687
P5875ResearchGate publication ID13265199

P2093author name stringWitte DP
Aronow BJ
Ess KC
Bascomb CP
P2860cites workThe homeobox gene GBX2, a target of the myb oncogene, mediates autocrine growth and monocyte differentiationQ24321626
TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiationQ24532233
Arrest of spermatogenesis and defective breast development in mice lacking A-mybQ28235377
Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fateQ28287796
Coordinate developmental regulation of purine catabolic enzyme expression in gastrointestinal and postimplantation reproductive tractsQ28333495
Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient miceQ29618462
Only the DNA binding and transactivation domains of c-Myb are required to block terminal differentiation of murine erythroleukemia cellsQ30450271
c-Myb and Ets proteins synergize to overcome transcriptional repression by ZEB.Q33886947
Biologic and therapeutic significance of MYB expression in human melanomaQ35237618
Activation of c-myb is an early bone-marrow event in a murine model for acute promonocytic leukemiaQ36118536
Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epitheQ36531978
Dissecting a locus control region: facilitation of enhancer function by extended enhancer-flanking sequencesQ36567376
The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axisQ36664519
Expression of a proto-oncogene (proto-myb) in hemopoietic tissues of miceQ36945427
Mouse A-myb encodes a trans-activator and is expressed in mitotically active cells of the developing central nervous system, adult testis and B lymphocytesQ37640063
Myb and Ets proteins cooperate to transactivate an early myeloid geneQ38296597
Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factorsQ38312442
The role of Myb proteins in normal and neoplastic cell proliferationQ38313050
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesisQ38335144
A central role for a single c-Myb binding site in a thymic locus control regionQ40017390
Core binding factor cannot synergistically activate the myeloperoxidase proximal enhancer in immature myeloid cells without c-MybQ40023226
Myb: an old oncoprotein with new rolesQ40520046
Differentiation and self-renewal in the mouse gastrointestinal epitheliumQ40606610
Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesisQ40654963
Activation of Heat Shock Transcription Factor 3 by c-Myb in the Absence of Cellular StressQ41099803
Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell typesQ41558201
Interleukin-6- and leukemia inhibitory factor-induced terminal differentiation of myeloid leukemia cells is blocked at an intermediate stage by constitutive c-mycQ41685649
Expression of the bcl-2 protooncogene in the cycling adult mouse hair follicleQ42495331
Murine A-myb gene encodes a transcription factor, which cooperates with Ets-2 and exhibits distinctive biochemical and biological activities from c-mybQ42797482
Functional analysis of the human adenosine deaminase gene thymic regulatory region and its ability to generate position-independent transgene expressionQ43183220
Evidence for a complex regulatory array in the first intron of the human adenosine deaminase geneQ45058501
Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: The architecture of a transduced oncogeneQ48401806
Developmental expression of SI is regulated in transgenic mice by an evolutionarily conserved promoter.Q52193795
Dominant interfering alleles define a role for c-Myb in T-cell development.Q52217579
Expression of the c-myb proto-oncogene during cellular proliferationQ59076968
CBP as a transcriptional coactivator of c-MybQ64382929
G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-mybQ69518975
Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic miceQ70634825
c-Myb repression of c-erbB-2 transcription by direct binding to the c-erbB-2 promoterQ72167828
Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cyclesQ72330471
Changes in expression of apoptosis-associated genes in skin mark early catagenQ72353185
Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell linesQ73306366
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1103-1111
P577publication date1999-01-01
P1433published inOncogeneQ1568657
P1476titleDiverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation.
P478volume18

Reverse relations

cites work (P2860)
Q30308928A Myb dependent pathway maintains Friend murine erythroleukemia cells in an immature and proliferating state
Q54228637C-myb Regulates Autophagy for Pulp Vitality in Glucose Oxidative Stress.
Q36962507CDK9 inhibitors selectively target estrogen receptor-positive breast cancer cells through combined inhibition of MYB and MCL-1 expression.
Q30433753Critical functions for c-Myb at three checkpoints during thymocyte development
Q39728276Expression and characterization of c-Myb in prenatal odontogenesis
Q42816800Gene delivery of c-myb increases bone formation surrounding oral implants
Q37109882High blood sugar levels significantly impact the prognosis of colorectal cancer patients through down-regulation of microRNA-16 by targeting Myb and VEGFR2.
Q84231252Identification of novel transcription-regulating genes expressed during murine molar development
Q43937133Localization of c-MYB in differentiated cells during postnatal molar and alveolar bone development
Q34173485MYB suppresses differentiation and apoptosis of human breast cancer cells
Q46844148Mouse Incisor Stem Cell Niche and Myb Transcription Factors
Q34576950Myb permits multilineage airway epithelial cell differentiation
Q28509990Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity
Q40686888Phosphorylation-dependent down-regulation of c-Myb DNA binding is abrogated by a point mutation in the v-myb oncogene
Q33719480Potential tumor suppressor role for the c-Myb oncogene in luminal breast cancer.
Q36478451Primitive erythropoiesis and megakaryopoiesis in the yolk sac are independent of c-myb
Q39918427Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb.
Q52853827Reduced c-myb expression levels affect hematopoietic development in vitro.
Q24798591Selective inhibition of c-Myb DNA-binding by RNA polymers
Q92602305Sex-determining region Y (SRY) attributes to gender differences in RANKL expression and incidence of osteoporosis
Q40722533Targeted disruption of c-myb in the chicken pre B-cell line DT40.
Q40811029The chicken Pdcd4 gene is regulated by v-Myb
Q38297440The highly conserved DNA-binding domains of A-, B- and c-Myb differ with respect to DNA-binding, phosphorylation and redox properties
Q42944483The upstream enhancer is necessary and sufficient for the expression of the pre-T cell receptor alpha gene in immature T lymphocytes
Q42480003Thymic Tumor With Adenoid Cystic Carcinoma-Like Features: A Study of a Clinically Favorable Case Followed for 9 Years
Q64952041Transcription regulation of MYB: a potential and novel therapeutic target in cancer.
Q34401921Transcriptional regulation of hemopoiesis
Q36336577c-Myb a stem-progenitor cell regulator in multiple tissue compartments.
Q33606245c-Myb binds to a sequence in the proximal region of the RAG-2 promoter and is essential for promoter activity in T-lineage cells
Q30432940c-Myb promotes the survival of CD4+CD8+ double-positive thymocytes through upregulation of Bcl-xL
Q51084029v-Myb can transform and regulate the differentiation of melanocyte precursors.

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