| scholarly article | Q13442814 |
| P50 | author | Jason M Kinchen | Q63444300 |
| P2093 | author name string | Michael J Gambello | |
| Robert A Casero | |||
| Teodoro Bottiglieri | |||
| Tracy Murray-Stewart | |||
| David Kapfhamer | |||
| Brandi Wasek | |||
| James McKenna Iii | |||
| Matthew Dunworth | |||
| P2860 | cites work | TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1 | Q24293153 |
| The ornithine decarboxylase gene is a transcriptional target of c-Myc | Q24561758 | ||
| The TSC1-TSC2 complex: a molecular switchboard controlling cell growth | Q24645204 | ||
| Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis | Q24648897 | ||
| A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 | ||
| Remaining Mysteries of Molecular Biology: The Role of Polyamines in the Cell | Q26866286 | ||
| Appetite for destruction: the inhibition of glycolysis as a therapy for tuberous sclerosis complex-related tumors | Q27015394 | ||
| Organization of GC/MS and LC/MS metabolomics data into chemical libraries | Q27702050 | ||
| Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34 | Q28245141 | ||
| Giant cells: contradiction to two-hit model of tuber formation? | Q28256696 | ||
| Identification and characterization of the tuberous sclerosis gene on chromosome 16 | Q28257738 | ||
| RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs | Q28286431 | ||
| Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome | Q28307704 | ||
| Catalytic mechanism of guanidinoacetate methyltransferase: crystal structures of guanidinoacetate methyltransferase ternary complexes | Q28579116 | ||
| Activation of a metabolic gene regulatory network downstream of mTOR complex 1 | Q29615179 | ||
| Molecular mechanisms of mTOR-mediated translational control | Q29615529 | ||
| Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction | Q29616653 | ||
| The tuberous sclerosis complex | Q29619128 | ||
| Effect of mutations at active site residues on the activity of ornithine decarboxylase and its inhibition by active site-directed irreversible inhibitors. | Q30421406 | ||
| Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex. | Q30497818 | ||
| The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex. | Q30518266 | ||
| Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex. | Q30573030 | ||
| Inborn errors of creatine metabolism and epilepsy | Q30577669 | ||
| A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits | Q30597707 | ||
| Astrocyte-neuronal interactions in epileptogenesis. | Q30911884 | ||
| Haploinsufficiency in tumor predisposition syndromes: altered genomic transcription in morphologically normal cells heterozygous for VHL or TSC mutation | Q33566604 | ||
| eIF4E expression in tumors: its possible role in progression of malignancies | Q33601639 | ||
| Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide | Q33649179 | ||
| Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors | Q33784370 | ||
| CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function | Q33836737 | ||
| Biallelic TSC gene inactivation in tuberous sclerosis complex | Q33899858 | ||
| The metabolic burden of creatine synthesis | Q34169402 | ||
| Metabolomic evaluation of Mitomycin C and rapamycin in a personalized treatment of pancreatic cancer. | Q34292602 | ||
| The multi-functional roles of GNMT in toxicology and cancer | Q34311379 | ||
| The role of genetics in the establishment and maintenance of the epigenome. | Q34649133 | ||
| Plasma S-adenosylmethionine, DNMT polymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore | Q34955668 | ||
| Reactive astrogliosis causes the development of spontaneous seizures | Q35117565 | ||
| Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway | Q35213308 | ||
| Interaction of polyamines and mTOR signaling in the synthesis of antizyme (AZ). | Q35853765 | ||
| Betaine: a key modulator of one-carbon metabolism and homocysteine status | Q36273334 | ||
| Hypomyelination following deletion of Tsc2 in oligodendrocyte precursors. | Q36410278 | ||
| S-adenosylmethionine and its products | Q36749954 | ||
| Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases | Q36803757 | ||
| Possible mechanisms of disease development in tuberous sclerosis | Q37051667 | ||
| S-Adenosylmethionine in cell growth, apoptosis and liver cancer | Q37108891 | ||
| Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse | Q37128350 | ||
| The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway | Q37235361 | ||
| Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model. | Q37272605 | ||
| Everolimus for subependymal giant cell astrocytoma: 5-year final analysis | Q37337337 | ||
| Everolimus: in patients with subependymal giant cell astrocytoma associated with tuberous sclerosis complex | Q37963968 | ||
| Connecting mTORC1 signaling to SREBP-1 activation | Q37997206 | ||
| Fulfilling the metabolic requirements for cell proliferation | Q38029807 | ||
| Contributions of astrocytes to epileptogenesis following status epilepticus: opportunities for preventive therapy? | Q38069770 | ||
| Folate, vitamin B₁₂, and S-adenosylmethionine | Q38093959 | ||
| Everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: 2-year open-label extension of the randomised EXIST-1 study | Q38279723 | ||
| Neurological and neuropsychiatric aspects of tuberous sclerosis complex | Q38525506 | ||
| Changes in Methionine Metabolism and Histone H3 Trimethylation Are Linked to Mitochondrial Defects in Multiple Sclerosis | Q38820198 | ||
| mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle | Q38910153 | ||
| Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites | Q38927327 | ||
| Targeting polyamine metabolism for cancer therapy and prevention | Q38966691 | ||
| Arginine Methylation: The Coming of Age. | Q39070637 | ||
| Cystathionine β-synthase deficiency: Of mice and men. | Q39352707 | ||
| Dynamic RNA Modifications in Gene Expression Regulation | Q39378718 | ||
| Systemic availability of guanidinoacetate affects GABAA receptor function and seizure threshold in GAMT deficient mice. | Q39981198 | ||
| Complex Neurological Phenotype in Mutant Mice Lacking Tsc2 in Excitatory Neurons of the Developing Forebrain(123). | Q40182298 | ||
| A brain proteomic investigation of rapamycin effects in the Tsc1+/- mouse model | Q41211684 | ||
| c-Myc induces the expression and activity of ornithine decarboxylase. | Q41515721 | ||
| Characterization of a transgenic mouse line over-expressing the human ornithine decarboxylase gene | Q42862479 | ||
| The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels | Q43788337 | ||
| Polyamine metabolism and glutamate receptor agonists-mediated excitotoxicity in the rat brain | Q43825398 | ||
| Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation. | Q45205869 | ||
| Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex. | Q45339901 | ||
| Congenital subependymal giant cell astrocytoma: clinical considerations and expression of radial glial cell markers in giant cells | Q46482262 | ||
| Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study | Q46573072 | ||
| Twenty-five years of mTOR: Uncovering the link from nutrients to growth. | Q47159548 | ||
| Subependymal giant cell astrocytoma: a clinicopathological study of 23 cases with special emphasis on proliferative markers and expression of p53 and retinoblastoma gene proteins | Q47327182 | ||
| Animal models of acquired epilepsy: insights into mechanisms of human epileptogenesis | Q47582422 | ||
| Increases in brain polyamine concentrations in chemical kindling and single convulsion induced by pentylenetetrazol in rats | Q48347867 | ||
| Heterozygosity for the tuberous sclerosis complex (TSC) gene products results in increased astrocyte numbers and decreased p27-Kip1 expression in TSC2+/- cells. | Q48592496 | ||
| Dysregulation of methionine metabolism in multiple sclerosis | Q50101474 | ||
| Elevated seizure threshold and impaired spatial learning in transgenic mice with putrescine overproduction in the brain. | Q52061216 | ||
| Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: improved separation systems for polyamines in cerebrospinal fluid, urine and tissue | Q69593259 | ||
| Heterogeneous distribution of polyamines in temporal lobe epilepsy | Q77893194 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P921 | main subject | tuberous sclerosis | Q1362721 |
| P577 | publication date | 2018-04-09 | |
| P1433 | published in | Human Molecular Genetics | Q2720965 |
| P1476 | title | Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex. |
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