Elucidating the folding problem of helical peptides using empirical parameters.

scientific article published in June 1994

Elucidating the folding problem of helical peptides using empirical parameters. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NSB0694-399
P698PubMed publication ID7664054
P5875ResearchGate publication ID15535212

P2093author name stringSerrano L
Muñoz V
P2860cites workA novel, highly stable fold of the immunoglobulin binding domain of streptococcal protein GQ27651724
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A thermodynamic scale for the helix-forming tendencies of the commonly occurring amino acidsQ44211659
Conformation of uteroglobin fragments.Q44303247
Parameters of helix-coil transition theory for alanine-based peptides of varying chain lengths in waterQ44844504
Further studies of the helix dipole model: effects of a free alpha-NH3+ or alpha-COO- group on helix stabilityQ45735421
Effect of the substitution Ala----Gly at each of five residue positions in the C-peptide helixQ46045772
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Effect of trifluoroethanol on protein secondary structure: an NMR and CD study using a synthetic actin peptideQ46579127
Relative helix-forming tendencies of nonpolar amino acidsQ46587484
Capping interactions in isolated alpha helices: position-dependent substitution effects and structure of a serine-capped peptide helixQ46782457
Large differences in the helix propensities of alanine and glycineQ46971709
The contribution of helical potential to the in vitro receptor binding activity of a neuropeptide Y N-terminal deletion fragment.Q48237904
Residue helix parameters obtained from dichroic analysis of peptides of defined sequence.Q52393344
Calculation of conformational ensembles from potentials of mean force. An approach to the knowledge-based prediction of local structures in globular proteins.Q52451138
Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.Q52900971
Theory of the Phase Transition between Helix and Random Coil in Polypeptide ChainsQ56522033
Peptide conformation and protein foldingQ57078381
Periodic properties of proton conformational shifts in isolated protein helices. An experimental studyQ58622097
The homologous angiogenin and ribonuclease N-terminal fragments fold into very similar helices when isolatedQ58622102
1 H NMR and CD evidence of the folding of the isolated ribonuclease 50-61 fragmentQ58622130
Position-dependent stabilizing effects in .alpha.-helices: N-terminal capping in synthetic model peptidesQ58881395
Tests of the helix dipole model for stabilization of α-helicesQ59076470
Positional independence and additivity of amino acid replacements on helix stability in monomeric peptidesQ67290878
Alpha-helix stability in proteins. I. Empirical correlations concerning substitution of side-chains at the N and C-caps and the replacement of alanine by glycine or serine at solvent-exposed surfacesQ67559626
A molecular thermodynamic approach to predict the secondary structure of homopolypeptides in aqueous systemsQ67571824
Conformations in solution of angiotensin II, and its 1-7 and 1-6 fragmentsQ67571855
A theory of protein molecule self-organization. IV. Helical and irregular local structures of unfolded protein chainsQ67792886
Helix propagation in trifluoroethanol solutionsQ67974558
Physical reasons for secondary structure stability: alpha-helices in short peptidesQ68051375
Histidine residues at the N- and C-termini of alpha-helices: perturbed pKas and protein stabilityQ68064200
The folding of an enzyme. VI. The folding pathway of barnase: comparison with theoretical modelsQ68101608
Effect of amino acid ion pairs on peptide helicityQ68193286
Effect of central-residue replacements on the helical stability of a monomeric peptideQ68577440
Side chain contributions to the stability of alpha-helical structure in peptidesQ68598333
Side-chain interactions in the C-peptide helix: Phe 8 ... His 12+Q68758939
Folding of a peptide corresponding to the alpha-helix in bovine pancreatic trypsin inhibitorQ69692741
NMR and circular dichroic studies on the solution conformation of a synthetic peptide derived from the calmodulin-binding domain of Bordetella pertussis adenylate cyclaseQ70113703
Effect of end group blockage on the properties of a class A amphipathic helical peptideQ70628260
Helix-coil transition of the isolated amino terminus of ribonucleaseQ71758379
Single-residue substitution in homopolypeptides: perturbative helix-coil theory at a single siteQ72553279
Stabilization of alpha-helix in C-terminal fragments of neuropeptide YQ72632833
Helix stop signals in proteins and peptides: the capping boxQ72871450
Residual helical structure in the C-terminal fragment of cytochrome cQ72956139
P433issue6
P304page(s)399-409
P577publication date1994-06-01
P1433published inNature structural biologyQ26842658
P1476titleElucidating the folding problem of helical peptides using empirical parameters.
P478volume1

Reverse relations

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Q50959391Structure and mechanism of maximum stability of isolated alpha-helical protein domains at a critical length scale.
Q34325473Structured disorder and conformational selection
Q41869317Study of the Structure-Function-Stability Relationships in Yeast D-amino Acid Oxidase: Hydrophobization of Alpha-Helices.
Q36199011Synergy between simulation and experiment in describing the energy landscape of protein folding
Q39594170Synthesis, conformational analysis and biological properties of a dicarba derivative of the antimicrobial peptide, brevinin-1BYa
Q42265347Synthesis, folding, and structure of the beta-turn mimic modified B1 domain of streptococcal protein G.
Q48966042Targeting EphA2-Sam and Its Interactome: Design and Evaluation of Helical Peptides Enriched in Charged Residues.
Q24296551Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein. Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7
Q41975597Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?
Q57998252The Chemical Shift Index method applied to resin-bound peptides
Q52550317The Molecular Basis for the pH-activation Mechanism in the Channel-forming Bacterial Colicin E1
Q42121729The N(0)-binding region of the vesicular stomatitis virus phosphoprotein is globally disordered but contains transient α-helices
Q39442233The N-terminal helix α(0) of hepatitis C virus NS3 protein dictates the subcellular localization and stability of NS3/NS4A complex
Q30385977The Unstructured N-terminal Region of Arabidopsis Group 4 Late Embryogenesis Abundant (LEA) Proteins Is Required for Folding and for Chaperone-like Activity under Water Deficit.
Q43095035The dimerization domain of the HIV-1 capsid protein binds a capsid protein-derived peptide: a biophysical characterization
Q42094108The distribution of alpha-helix propensity along the polypeptide chain is not conserved in proteins from the same family
Q52077265The duplication of an eight-residue helical stretch in Staphylococcal nuclease is not helical: a model for evolutionary change.
Q40892983The effect of side-chain functionality and hydrophobicity on the gene delivery capabilities of cationic helical polypeptides
Q34037348The ensemble folding kinetics of protein G from an all-atom Monte Carlo simulation
Q41869373The fast-folding HP35 double mutant has a substantially reduced primary folding free energy barrier
Q52342671The hydrophobic-staple motif and a role for loop-residues in alpha-helix stability and protein folding.
Q41920394The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses
Q30359800The mechanical unfolding of ubiquitin through all-atom Monte Carlo simulation with a Go-type potential.
Q72033152The nature of the alpha-helix
Q44352737The proenkephalin A-processing product peptide E, which encompasses two enkephalin sequences, has a much lower opioid activity than beta-endorphin
Q33883809The relationship between sequence and structure in elementary folding units
Q73594386The relative order of helical propensity of amino acids changes with solvent environment
Q42845907The role of context on alpha-helix stabilization: host-guest analysis in a mixed background peptide model
Q38269751The role of disulfide bond in the amyloidogenic state of beta(2)-microglobulin studied by heteronuclear NMR.
Q80808878The role of sequence and structure in protein folding kinetics; the diffusion-collision model applied to proteins L and G
Q42552259The role of the N-terminal tail for the oligomerization, folding and stability of human frataxin
Q33717508The structure of calreticulin C-terminal domain is modulated by physiological variations of calcium concentration
Q27677943The structure of the SBP-Tag-streptavidin complex reveals a novel helical scaffold bridging binding pockets on separate subunits
Q36281322The turn sequence directs beta-strand alignment in designed beta-hairpins
Q41995938Theory for protein folding cooperativity: helix bundles
Q24322769Thermodynamic analysis of Jun-Fos coiled coil peptide antagonists
Q36438102Thermodynamics Of alpha-Helix Formation
Q27662288Three-dimensional Structure of the NLRP7 Pyrin Domain: INSIGHT INTO PYRIN-PYRIN-MEDIATED EFFECTOR DOMAIN SIGNALING IN INNATE IMMUNITY
Q27730189Three-dimensional structure of chemotactic Che Y protein in aqueous solution by nuclear magnetic resonance methods
Q27639026Three-dimensional structure of the S4-S5 segment of the Shaker potassium channel
Q30557963Toward an improved structural model of the frog-skin antimicrobial peptide esculentin-1b(1-18).
Q58749822Tracing a protein's folding pathway over evolutionary time using ancestral sequence reconstruction and hydrogen exchange
Q39281555Transformation of the naturally occurring frog skin peptide, alyteserin-2a into a potent, non-toxic anti-cancer agent
Q31957768Unfolding and inactivation of monomeric superoxide dismutase from E. coli by SDS.
Q47226964Unified understanding of folding and binding mechanisms of globular and intrinsically disordered proteins
Q36579566Unique features of the anti-parallel, heterodimeric coiled-coil interaction between methyl-cytosine binding domain 2 (MBD2) homologues and GATA zinc finger domain containing 2A (GATAD2A/p66α)
Q41682090Unveiling the folding mechanism of the Bromodomains
Q40816673WW: An isolated three-stranded antiparallel beta-sheet domain that unfolds and refolds reversibly; evidence for a structured hydrophobic cluster in urea and GdnHCl and a disordered thermal unfolded state
Q37083716Waltzing alpha-helices
Q38869249Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultra-Stable Helical Conformations
Q34215870What can we learn about protein folding from Ising-like models?
Q35433515What determines the activity of antimicrobial and cytolytic peptides in model membranes
Q34084053alpha-helix formation: discontinuous molecular dynamics on an intermediate-resolution protein model
Q71952360α-Helix formation by peptides of defined sequence

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