Insights into innate immune signalling in controlling cardiac remodelling.

scientific article published in November 2017

Insights into innate immune signalling in controlling cardiac remodelling. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/CVR/CVX130
P698PubMed publication ID29088374

P2093author name stringHongliang Li
Zan Huang
Yaxing Zhang
P2860cites workTAK1 is a ubiquitin-dependent kinase of MKK and IKKQ24291454
Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...Q24297037
IFI16 is an innate immune sensor for intracellular DNAQ24301720
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infectionQ24302985
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathwayQ24306635
Peroxisomes are signaling platforms for antiviral innate immunityQ24310723
ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathwaysQ24313068
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune responseQ24316320
Direct activation of protein kinases by unanchored polyubiquitin chainsQ24324679
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogensQ24338114
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activationQ24652200
Immunometabolism governs dendritic cell and macrophage functionQ26773266
Innate immunity and cardiomyocytes in ischemic heart diseaseQ27003911
Mechanisms of TGF-beta signaling from cell membrane to the nucleusQ27860785
The coiled-coil domain of TRAF6 is essential for its auto-ubiquitinationQ27919663
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RIG-I-like receptor regulation in virus infection and immunityQ28081647
Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunityQ28118774
Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemiaQ28182436
Innate immune pattern recognition: a cell biological perspectiveQ28255348
TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chainsQ28278500
Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytesQ28366026
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunityQ28504584
The receptor NLRP3 is a transcriptional regulator of TH2 differentiationQ28512758
NOD1 activation induces cardiac dysfunction and modulates cardiac fibrosis and cardiomyocyte apoptosisQ28579741
Interferon regulatory factor signalings in cardiometabolic diseasesQ38528480
The unique role of STAT2 in constitutive and IFN-induced transcription and antiviral responses.Q38800260
Inflammasomes: mechanism of assembly, regulation and signallingQ38862650
Post-Translational Modification Control of Innate ImmunityQ38903391
Reprogramming Innate Immune Signaling in Cardiometabolic DiseaseQ39188744
NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotectiveQ40169693
The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.Q40451032
NOD1, a new player in cardiac function and calcium handling.Q41138874
Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in miceQ41163325
Tumor necrosis factor receptor-associated factor 3 is a positive regulator of pathological cardiac hypertrophyQ41190651
A role for APPL1 in TLR3/4-dependent TBK1 and IKKε activation in macrophages.Q41424373
Tumor necrosis factor receptor-associated factor 2 signaling provokes adverse cardiac remodeling in the adult mammalian heartQ41518012
Toll-like receptor 4 mutation suppresses hyperhomocysteinemia-induced hypertensionQ41630351
Toll-like receptor-2 mediates adaptive cardiac hypertrophy in response to pressure overload through interleukin-1β upregulation via nuclear factor κB activationQ41862491
Central blockade of TLR4 improves cardiac function and attenuates myocardial inflammation in angiotensin II-induced hypertensionQ42229127
Disruption of tumor necrosis factor receptor associated factor 5 exacerbates pressure overload cardiac hypertrophy and fibrosisQ42269363
Toll-like receptor 5 deficiency attenuates interstitial cardiac fibrosis and dysfunction induced by pressure overload by inhibiting inflammation and the endothelial-mesenchymal transitionQ42481440
Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome.Q42732446
The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β.Q42832204
Nuclear factor-kappaB protects the adult cardiac myocyte against ischemia-induced apoptosis in a murine model of acute myocardial infarction.Q44693877
Blockade of NF-kappaB improves cardiac function and survival after myocardial infarctionQ44731224
Interleukin-1β blockade improves cardiac remodelling after myocardial infarction without interrupting the inflammasome in the mouseQ44980873
Inhibition of the NLRP3 inflammasome limits the inflammatory injury following myocardial ischemia-reperfusion in the mouseQ45027851
Cardiac-specific blockade of NF-kappaB in cardiac pathophysiology: differences between acute and chronic stimuli in vivoQ45253902
Interferon regulatory factor 9 protects against cardiac hypertrophy by targeting myocardinQ45847502
NF-kappaB activation is required for adaptive cardiac hypertrophy.Q45924674
Cardiac-specific Traf2 overexpression enhances cardiac hypertrophy through activating AKT/GSK3β signaling.Q45932209
Reduced cardiac hypertrophy in toll-like receptor 4-deficient mice following pressure overloadQ46557239
Toll-like receptor 4-deficient mice are resistant to chronic hypoxia-induced pulmonary hypertensionQ46570302
Inhibitory Effects of Hydrogen on Proliferation and Migration of Vascular Smooth Muscle Cells via Down-Regulation of Mitogen/Activated Protein Kinase and Ezrin-Radixin-Moesin Signaling PathwaysQ46596209
Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient miceQ47200145
NOD2 deletion promotes cardiac hypertrophy and fibrosis induced by pressure overloadQ47745538
NOD2 contributes to myocardial ischemia/reperfusion injury by regulating cardiomyocyte apoptosis and inflammation.Q50204712
Interferon regulatory factor 9 is a key mediator of hepatic ischemia/reperfusion injury.Q51061341
Interferon regulatory factor 1 attenuates vascular remodeling; roles of angiotensin II type 2 receptor.Q51532773
Targeting TRAF3 signaling protects against hepatic ischemia/reperfusions injury.Q53358508
TRAF6-Mediated SM22α K21 Ubiquitination Promotes G6PD Activation and NADPH Production, Contributing to GSH Homeostasis and VSMC Survival In Vitro and In Vivo.Q53372809
Toll-like receptor 5 deficiency exacerbates cardiac injury and inflammation induced by myocardial ischaemia-reperfusion in the mouse.Q53395166
Nlrp3 plays no role in acute cardiac infarction due to low cardiac expression.Q53670996
Tumor necrosis factor receptor-associated factor 5 (Traf5) acts as an essential negative regulator of hepatic steatosis.Q53791702
NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice.Q54389267
Interferon regulatory factor 3 constrains IKKβ/NF-κB signaling to alleviate hepatic steatosis and insulin resistance.Q54403182
Survival and cardiac remodeling after myocardial infarction are critically dependent on the host innate immune interleukin-1 receptor-associated kinase-4 signaling: a regulator of bone marrow-derived dendritic cells.Q54719546
Activation of NOD1 by DAP contributes to myocardial ischemia/reperfusion injury via multiple signaling pathways.Q55068540
IRF4 is a key thermogenic transcriptional partner of PGC-1αQ28590968
The mammalian PYHIN gene family: phylogeny, evolution and expressionQ28727434
Inflammation, atherosclerosis, and coronary artery diseaseQ29547232
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral responseQ29617083
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMOQ29618712
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]Q29618714
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosisQ33478396
IRF4 is a novel mediator for neuronal survival in ischaemic strokeQ33580173
MicroRNA-125b protects against myocardial ischaemia/reperfusion injury via targeting p53-mediated apoptotic signalling and TRAF6.Q33648129
Selective C-Rel activation via Malt1 controls anti-fungal T(H)-17 immunity by dectin-1 and dectin-2.Q33809396
Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokinesQ33861276
The cytoprotective effects of tumor necrosis factor are conveyed through tumor necrosis factor receptor-associated factor 2 in the heartQ34022068
Brain microglial cytokines in neurogenic hypertensionQ34089804
The cardiac beta-myosin heavy chain isogene is induced selectively in alpha 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytesQ34248415
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failureQ34270939
Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signalingQ34357976
Interferon regulatory factor 9 is critical for neointima formation following vascular injuryQ34446578
IKKi deficiency promotes pressure overload-induced cardiac hypertrophy and fibrosisQ34562186
Essential role of Smad3 in angiotensin II-induced vascular fibrosisQ34575283
Transcriptional control of adipose lipid handling by IRF4Q34713714
Cardiac plasticityQ34764732
Transforming growth factor β-activated kinase 1 signaling pathway critically regulates myocardial survival and remodelingQ34995991
Tumor necrosis factor receptor-associated factor 2 mediates mitochondrial autophagyQ35001980
Cardiomyocyte p65 nuclear factor-κB is necessary for compensatory adaptation to pressure overloadQ35002059
The immune system and hypertension.Q35038155
Interferon regulatory factor 7 protects against vascular smooth muscle cell proliferation and neointima formationQ35070759
Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertensionQ35110074
Pharmacological postconditioning effect of muramyl dipeptide is mediated through RIP2 and TAK1Q35135046
The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse.Q35621283
Angiotensin II-induced hypertension is modulated by nuclear factor-κBin the paraventricular nucleus.Q35707198
Hepatic TRAF2 regulates glucose metabolism through enhancing glucagon responses.Q35766938
Signaling by myeloid C-type lectin receptors in immunity and homeostasisQ35779708
Pharmacologic Inhibition of the NLRP3 Inflammasome Preserves Cardiac Function After Ischemic and Nonischemic Injury in the MouseQ35847003
MyD88 mediated inflammatory signaling leads to CaMKII oxidation, cardiac hypertrophy and death after myocardial infarction.Q35892464
Interaction between NFκB and NFAT coordinates cardiac hypertrophy and pathological remodelingQ35926510
Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and AktQ35929017
Dual Activation of TRIF and MyD88 Adaptor Proteins by Angiotensin II Evokes Opposing Effects on Pressure, Cardiac Hypertrophy, and Inflammatory Gene Expression.Q35956355
Inhibitory kappa-B kinase-β inhibition prevents adaptive left ventricular hypertrophyQ36110312
TRAF1 is a key mediator for hepatic ischemia/reperfusion injuryQ36291138
The interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseasesQ36342106
CpG-ODN, the TLR9 agonist, attenuates myocardial ischemia/reperfusion injury: involving activation of PI3K/Akt signalingQ36456832
Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signallingQ36591276
Increased expression of microRNA-146a decreases myocardial ischaemia/reperfusion injuryQ36596636
Tlr2 deficiency does not limit the development of left ventricular hypertrophy in a model of transverse aortic constriction induced pressure overloadQ36830845
HDAC-dependent ventricular remodelingQ36945016
The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling.Q36974840
Role of interferon regulatory factor 4 in the regulation of pathological cardiac hypertrophyQ37073978
Interferon regulatory factor 9 protects against hepatic insulin resistance and steatosis in male miceQ37078467
The IRF family transcription factors in immunity and oncogenesisQ37096072
Cardiomyocyte-specific p65 NF-κB deletion protects the injured heart by preservation of calcium handlingQ37234808
Pathological ventricular remodeling: mechanisms: part 1 of 2Q37241166
Pathological ventricular remodeling: therapies: part 2 of 2.Q37312758
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infectionQ37331568
Interferon regulatory factor 8 modulates phenotypic switching of smooth muscle cells by regulating the activity of myocardin.Q37546984
Dysferlin mediates the cytoprotective effects of TRAF2 following myocardial ischemia reperfusion injuryQ37648514
Role of extracellular RNA and TLR3-Trif signaling in myocardial ischemia-reperfusion injuryQ37648557
Interleukin-18 mediates interleukin-1-induced cardiac dysfunctionQ37656103
A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouseQ37692892
Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophyQ37698309
In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.Q37710952
Innate immune signaling in cardiac ischemiaQ37859249
The emerging role of innate immunity in the heart and vascular system: for whom the cell tollsQ37870040
The innate immune response in reperfused myocardiumQ37977824
C-type lectin receptors orchestrate antifungal immunityQ38036520
Interferon regulatory factors: at the crossroads of immunity, metabolism, and diseaseQ38210113
Microbial sensing by Toll-like receptors and intracellular nucleic acid sensorsQ38258737
Targeting hepatic TRAF1-ASK1 signaling to improve inflammation, insulin resistance, and hepatic steatosisQ38293912
NOD-like receptors: versatile cytosolic sentinels.Q38300466
Interferon regulatory factor 7 deficiency prevents diet-induced obesity and insulin resistanceQ38315303
In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarctionQ38343941
P433issue13
P304page(s)1538-1550
P577publication date2017-11-01
P1433published inCardiovascular ResearchQ4642329
P1476titleInsights into innate immune signalling in controlling cardiac remodelling.
P478volume113

Reverse relations

cites work (P2860)
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