Colocalization of cytosolic phospholipase A2, 5-lipoxygenase, and 5-lipoxygenase-activating protein at the nuclear membrane of A23187-stimulated human neutrophils.

scientific article published in May 1996

Colocalization of cytosolic phospholipase A2, 5-lipoxygenase, and 5-lipoxygenase-activating protein at the nuclear membrane of A23187-stimulated human neutrophils. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1432-1033.1996.0250Q.X
P698PubMed publication ID8665944
P5875ResearchGate publication ID14535218

P2093author name stringS R McColl
M Pouliot
P K Weech
P Borgeat
J A Mancini
E Krump
P P McDonald
P2860cites workRequirement of a 5-lipoxygenase-activating protein for leukotriene synthesisQ24299373
cPLA2 is phosphorylated and activated by MAP kinaseQ24314148
5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytesQ24320095
5-lipoxygenase-activating protein is an arachidonate binding proteinQ24321687
Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activationQ36207505
Translocation of the 85-kDa phospholipase A2 from cytosol to the nuclear envelope in rat basophilic leukemia cells stimulated with calcium ionophore or IgE/antigenQ41333836
Studies on the activation of human neutrophil 5-lipoxygenase induced by natural agonists and Ca2+ ionophore A23187Q42028772
Potential phospholipid source(s) of arachidonate used for the synthesis of leukotrienes by the human neutrophilQ42835632
Human Neutrophils Store Type II 14-kDa Phospholipase A2 in Granules and Secrete Active Enzyme in Response to Soluble StimuliQ45083156
Redistribution of 5-lipoxygenase and cytosolic phospholipase A2 to the nuclear fraction upon macrophage activation.Q52515271
Identification and isolation of a membrane protein necessary for leukotriene productionQ59059824
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)250-258
P577publication date1996-05-01
P1433published inFEBS JournalQ1388041
P1476titleColocalization of cytosolic phospholipase A2, 5-lipoxygenase, and 5-lipoxygenase-activating protein at the nuclear membrane of A23187-stimulated human neutrophils.
P478volume238

Reverse relations

cites work (P2860)
Q465163671-Oleoyl-2-acetylglycerol stimulates 5-lipoxygenase activity via a putative (phospho)lipid binding site within the N-terminal C2-like domain
Q403767775-Lipoxygenase-activating protein homodimer in human neutrophils: evidence for a role in leukotriene biosynthesis
Q281916195-lipoxygenase and FLAP
Q42462518A relationship between 5-lipoxygenase-activating protein and bcl-xL expression in murine pro-B lymphocytic FL5.12 cells
Q77391856Activation of nuclear factor-kappaB by lipopolysaccharide in mononuclear leukocytes is prevented by inhibitors of cytosolic phospholipase A2
Q33836735Adenosine, a potent natural suppressor of arachidonic acid release and leukotriene biosynthesis in human neutrophils
Q34997961Arachidonate 5-lipoxygenase
Q46794842Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils
Q44834974Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway
Q33595339Asthma and leukotrienes: antileukotrienes as novel anti-asthmatic drugs.
Q74345295Characteristics of leukotriene biosynthesis by human granulocytes in presence of plasma
Q41446246Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils
Q24291745Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75
Q30658785Colocalization of leukotriene C synthase and microsomal glutathione S-transferase elucidated by indirect immunofluorescence analysis.
Q40997040Cyclooxygenase-2 up-regulation after FLAP transfection in human adenocarcinoma cell line HT29 cl.19A.
Q44881324Cytosolic phospholipase A2 is responsible for prostaglandin E2 and leukotriene B4 formation in phagocyte-like PLB-985 cells: studies of differentiated cPLA2-deficient PLB-985 cells
Q34066023Dimerization of human 5-lipoxygenase
Q36568292Disruption of the alox5ap gene ameliorates focal ischemic stroke: possible consequence of impaired leukotriene biosynthesis
Q38936688DuCLOX-2/5 inhibition: a promising target for cancer chemoprevention
Q37003847ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma
Q28365981Epstein-Barr virus primes human polymorphonuclear leucocytes for the biosynthesis of leukotriene B4
Q24604441Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection
Q37015361Estradiol activates mast cells via a non-genomic estrogen receptor-alpha and calcium influx
Q28345080Evidence for the presence of phospholipid hydroperoxide glutathione peroxidase in human platelets: implications for its involvement in the regulatory network of the 12-lipoxygenase pathway of arachidonic acid metabolism
Q42083083Histamine-induced inhibition of leukotriene biosynthesis in human neutrophils: involvement of the H2 receptor and cAMP.
Q44225399Immunoblotting and sequential lysis protocols for the analysis of tyrosine phosphorylation-dependent signaling
Q24657427Interaction of 5-lipoxygenase with cellular proteins
Q33836695Intracellular compartmentalization of leukotriene biosynthesis
Q31860625Intracellular compartmentalization of leukotriene synthesis: unexpected nuclear secrets
Q28141404LTC4 synthase. Enzymology, biochemistry, and molecular characterization
Q42060492Linoleic acid peroxidation by Solanum tuberosum lipoxygenase was activated in the presence of human 5-lipoxygenase-activating protein
Q44541923Macrolide antibiotics inhibit prostaglandin E2 synthesis and mRNA expression of prostaglandin synthetic enzymes in human leukocytes
Q33681195Mammalian lysophospholipases.
Q34190664Membrane fluidity is a key modulator of membrane binding, insertion, and activity of 5-lipoxygenase
Q41049534Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSIS
Q41692683Multiple controls in inflammation. Extracellular and intracellular phospholipase A2, inducible and constitutive cyclooxygenase, and inducible nitric oxide synthase
Q27301317Nucleobindin co-localizes and associates with cyclooxygenase (COX)-2 in human neutrophils
Q44454211Phospholipase A2 modulates respiratory burst developed by neutrophils in patients with rheumatoid arthritis.
Q43892946Preservation of the pattern of tyrosine phosphorylation in human neutrophil lysates. II. A sequential lysis protocol for the analysis of tyrosine phosphorylation-dependent signalling
Q33705482The enzymology and pharmacology of 5-lipoxygenase and 5-lipoxygenase activating protein
Q28144667The molecular biology and regulation of 5-lipoxygenase
Q33862056Upregulation of cytosolic phospholipase A2 correlates with apoptosis in mouse superior cervical and dorsal root ganglia neurons

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