Progranulin ameliorates coxsackievirus-B3-induced viral myocarditis by downregulating Th1 and Th17 cells.

scientific article published on 3 April 2018

Progranulin ameliorates coxsackievirus-B3-induced viral myocarditis by downregulating Th1 and Th17 cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YEXCR.2018.04.001
P698PubMed publication ID29625085

P2093author name stringLi Li
Ling Li
Lili Xiao
Jiahong Shangguan
P2860cites workProgranulin as a biomarker and potential therapeutic agent.Q39398708
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Progranulin Plays a Central Role in Host Defense during Sepsis by Promoting Macrophage RecruitmentQ40686335
Progranulin deficiency exaggerates, whereas progranulin-derived Atsttrin attenuates, severity of dermatitis in mice.Q42156709
Progranulin Inhibits Human T Lymphocyte Proliferation by Inducing the Formation of Regulatory T LymphocytesQ42209627
PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissueQ42801261
Deletion of progranulin exacerbates atherosclerosis in ApoE knockout miceQ43485181
Progranulin promotes tumour necrosis factor-induced proliferation of suppressive mouse CD4⁺ Foxp3⁺ regulatory T cells.Q43856158
Th17 Cells Contribute to Viral Replication in Coxsackievirus B3-Induced Acute Viral MyocarditisQ44160967
PC cell-derived growth factor (PCDGF/GP88, progranulin) stimulates migration, invasiveness and VEGF expression in breast cancer cellsQ44875101
Acrosome biogenesis begins during meiosis: evidence from the synthesis and distribution of an acrosomal glycoprotein, acrogranin, during guinea pig spermatogenesisQ46888155
Progranulin overexpression predicts overall survival in patients with glioblastoma.Q48786361
Mapping of Grn, the gene encoding the granulin/epithelin precursor (acrogranin), to mouse chromosome 11Q71246859
Blockade of interleukin-17A protects against coxsackievirus B3-induced myocarditis by increasing COX-2/PGE2 production in the heartQ82807125
The role of Th17 cells and regulatory T cells in Coxsackievirus B3-induced myocarditisQ85083996
Serum progranulin irrelated with Breg cell levels, but elevated in RA patients, reflecting high disease activityQ86478450
Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domainsQ24305310
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.Q30592224
Cellular localization of gene expression for progranulinQ33180554
Epithelins 1 and 2: isolation and characterization of two cysteine-rich growth-modulating proteinsQ33838997
GP88 (progranulin): a novel tissue and circulating biomarker for non-small cell lung carcinomaQ34115676
Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).Q34235574
Progranulin as a prognostic biomarker for breast cancer recurrence in patients who had hormone receptor-positive tumors: a cohort study.Q34326604
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in miceQ35014661
Signal transduction pathways and transcriptional regulation in Th17 cell differentiationQ35238480
Progranulin facilitates conversion and function of regulatory T cells under inflammatory conditions.Q35418640
Insights into the role of progranulin in immunity, infection, and inflammationQ36534831
Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein sheddingQ36804675
Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activityQ36907736
Novel MMP-9 substrates in cancer cells revealed by a label-free quantitative proteomics approachQ36959251
Cytokine signaling modules in inflammatory responsesQ37133450
ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factorQ37275142
Inflammation in myocardial diseasesQ37973688
Viral myocarditis--diagnosis, treatment options, and current controversiesQ38551013
Elevated expression of secreted autocrine growth factor progranulin increases cervical cancer growthQ38938463
The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells.Q39388632
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmyocarditisQ186235
CoxsackievirusQ1138287
P304page(s)241-250
P577publication date2018-04-03
P1433published inExperimental Cell ResearchQ1524289
P1476titleProgranulin ameliorates coxsackievirus-B3-induced viral myocarditis by downregulating Th1 and Th17 cells.
P478volume367

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cites work (P2860)
Q90637369Analysis of factors of pulmonary fungal infection in mice in respiratory medicine department based on logistic regression analysis model and Progranulin
Q98160969Cardiac manifestations of COVID-19 in Shenzhen, China
Q99711182Progranulin Administration Attenuates β-Amyloid Deposition in the Hippocampus of 5xFAD Mice Through Modulating BACE1 Expression and Microglial Phagocytosis
Q55166882Roles of Host Immunity in Viral Myocarditis and Dilated Cardiomyopathy.

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