Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity.

scientific article published on 4 April 2018

Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1103128577
P356DOI10.1186/S13045-018-0595-3
P8608Fatcat IDrelease_tjfomjwubjgmnkz7et65cesumy
P932PMC publication ID5885466
P698PubMed publication ID29618368

P50authorWeicheng WuQ91598433
P2093author name stringJianxin Gu
Jing Wang
Yilin Wang
Shushu Song
Tianxiao Yang
Lan Fang
Jiangfan Zhou
Wenjuan Dai
Xixi Zheng
P2860cites workMIF signal transduction initiated by binding to CD74Q24303802
CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complexQ24307384
Mutations in B3GALNT2 cause congenital muscular dystrophy and hypoglycosylation of α-dystroglycanQ24321692
Links between metabolism and cancerQ24626229
Inflammation and cancerQ24649640
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008Q27860674
Macrophage migration inhibitory factor: a regulator of innate immunityQ28204158
The macrophage migration inhibitory factor-glucocorticoid dyad: regulation of inflammation and immunityQ28295198
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitmentQ28298072
A novel human beta1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAcbeta1-3GlcNAcQ28511795
Hepatocellular carcinomaQ29616359
Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolitesQ33896841
Expression of bisecting N-acetylglucosaminyltransferase-III in human hepatocarcinoma tissues, fetal liver tissues, and hepatoma cell lines of Hep3B and HepG2.Q34107206
A long-term follow-up and management study of hepatocellular carcinoma patients surviving for 10 years or longer after curative hepatectomy.Q50753723
Acetoacetate metabolism in AS-30D hepatoma cells.Q51594509
Addicted to AA (Acetoacetate): A Point of Convergence between Metabolism and BRAF Signaling.Q52307539
N-Acetylglucosaminyltransferase V exacerbates murine colitis with macrophage dysfunction and enhances colitic tumorigenesis.Q53352972
The inhibition of malignant cell growth by ketone bodiesQ53580986
Mechanism of a Reaction in Vitro Associated with Delayed-Type HypersensitivityQ61772241
N-Acetylglucosaminyltransferase V as a possible aid for the evaluation of tumor invasiveness in patients with hepatocellular carcinomaQ77792723
Macrophage migration inhibitory factor induces macrophage recruitment via CC chemokine ligand 2Q79370205
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexiaQ34193811
The sweet and sour of cancer: glycans as novel therapeutic targetsQ34439560
The macrophage migration inhibitory factor MIF is a phenylpyruvate tautomeraseQ34448866
Migration inhibitory factor expression in experimentally induced endotoxemiaQ35765238
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.Q35825254
An Analysis of MIF Structural Features that Control Functional Activation of CD74.Q36075317
Cunning factor: macrophage migration inhibitory factor as a redox-regulated targetQ37015273
Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screeningQ37187080
Alteration of protein glycosylation in liver diseasesQ37373750
Inflammation and liver cancer: new molecular links .Q37403661
Tumor-associated macrophages (TAM) as major players of the cancer-related inflammationQ37594369
Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 proteinQ37618668
Decreased expression of STING predicts poor prognosis in patients with gastric cancerQ37630679
Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathwaysQ37671165
Tumor-associated macrophages: from basic research to clinical applicationQ37671174
Role of tumor-associated macrophages in the progression of hepatocellular carcinomaQ37960792
Enzymatically inactive macrophage migration inhibitory factor inhibits monocyte chemotaxis and random migrationQ38320031
Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study.Q38416518
Glycosylation in cancer: mechanisms and clinical implicationsQ38569702
Control of tumor-associated macrophage alternative activation by macrophage migration inhibitory factorQ39198190
Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancerQ39234566
Ketone bodies affect the enzymatic activity of macrophage migration inhibitory factorQ40422713
MIF as a glucocorticoid-induced modulator of cytokine productionQ41296855
Tumor-associated macrophages, potential targets for cancer treatment.Q41318642
The inflammatory microenvironment in hepatocellular carcinoma: a pivotal role for tumor-associated macrophagesQ41481421
Acetoacetate reduces growth and ATP concentration in cancer cell lines which over-express uncoupling protein 2.Q41550485
Enzymatic basis of sugar structures of alpha-fetoprotein in hepatoma and hepatoblastoma cell lines: correlation with activities of alpha 1-6 fucosyltransferase and N-acetylglucosaminyltransferases III and VQ41624754
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress.Q41637048
Genome-wide survey of recurrent HBV integration in hepatocellular carcinomaQ44395085
Involvement of B3GALNT2 overexpression in the cell growth of breast cancerQ44668115
Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor GrowthQ47992732
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageQuantQ112270642
P433issue1
P304page(s)50
P577publication date2018-04-04
P1433published inJournal of Hematology & OncologyQ15724593
P1476titleIncreased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity.
P478volume11

Reverse relations

cites work (P2860)
Q93060431Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals
Q92542015Dysregulation of Ketone Body Metabolism Is Associated With Poor Prognosis for Clear Cell Renal Cell Carcinoma Patients
Q83600759Inactivation of 3-hydroxybutyrate dehydrogenase type 2 promotes proliferation and metastasis of nasopharyngeal carcinoma by iron retention

Search more.