Hidden genomic MHC disparity between HLA-matched sibling pairs in hematopoietic stem cell transplantation.

scientific article published on 29 March 2018

Hidden genomic MHC disparity between HLA-matched sibling pairs in hematopoietic stem cell transplantation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-018-23682-Y
P932PMC publication ID5876349
P698PubMed publication ID29599509

P50authorKati HyvärinenQ52620845
Satu KoskelaQ58879602
Tony KwanQ88220821
Jarmo RitariQ42118205
Jukka PartanenQ42707962
P2093author name stringTomi Pastinen
Riitta Niittyvuopio
Maija Itälä-Remes
P2860cites workPLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
A haplotype map of the human genomeQ24679827
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing dataQ27860742
Intensely punctate meiotic recombination in the class II region of the major histocompatibility complexQ28190352
A framework for variation discovery and genotyping using next-generation DNA sequencing dataQ29547262
Effective filtering strategies to improve data quality from population-based whole exome sequencing studies.Q30828110
From FastQ data to high confidence variant calls: the Genome Analysis Toolkit best practices pipelineQ30872351
Donor-recipient mismatch for common gene deletion polymorphisms in graft-versus-host diseaseQ33583414
Genomics of the major histocompatibility complex: haplotypes, duplication, retroviruses and diseaseQ33630704
A genome-wide study of Hardy-Weinberg equilibrium with next generation sequence dataQ33676593
Data quality control in genetic case-control association studies.Q33749328
An integrated haplotype map of the human major histocompatibility complexQ33906339
A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphismsQ33942154
MHC-resident variation affects risks after unrelated donor hematopoietic cell transplantationQ34290624
Major histocompatibility complex genomics and human diseaseQ34359146
Multi-population classical HLA type imputationQ34607788
Inheritable variable sizes of DNA stretches in the human MHC: conserved extended haplotypes and their fragments or blocksQ35177452
Mismatched HLA-DRB3 Can Induce a Potent Immune Response After HLA 10/10 Matched Stem Cell Transplantation.Q51115413
Graft rejection after unrelated donor hematopoietic stem cell transplantation for thalassemia is associated with nonpermissive HLA-DPB1 disparity in host-versus-graft direction.Q51959143
Effect of major histocompatibility complex haplotype matching by C4 and MICA genotyping on acute graft versus host disease in unrelated hematopoietic stem cell transplantation.Q52900700
Single nucleotide polymorphisms and outcome risk in unrelated mismatched hematopoietic stem cell transplantation: an exploration study.Q53168839
The discovery of linkage between the MHC and genetic control of the immune response.Q53420953
Cutadapt removes adapter sequences from high-throughput sequencing readsQ55953584
Ancestral haplotypes: conserved population MHC haplotypesQ67602836
The major histocompatability complex (MHC) contains conserved polymorphic genomic sequences that are shuffled by recombination to form ethnic-specific haplotypesQ73485677
A simplified method for screening siblings for HLA identity using short tandem repeat (STR) polymorphismsQ85842490
Congruence as a measurement of extended haplotype structure across the genome.Q35847732
Association of HLA-G low expressor genotype with severe acute graft-versus-host disease after sibling bone marrow transplantationQ35928084
High HLA-DP Expression and Graft-versus-Host DiseaseQ36028056
Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cellsQ36131690
The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantationQ36278732
Intrahaplotypic Variants Differentiate Complex Linkage Disequilibrium within Human MHC HaplotypesQ36305461
Mapping MHC haplotype effects in unrelated donor hematopoietic cell transplantationQ36666821
Donor-recipient mismatches in MHC class I chain-related gene A in unrelated donor transplantation lead to increased incidence of acute graft-versus-host diseaseQ36667913
Population-specific recombination sites within the human MHC regionQ37026918
Genetic similarity of chromosome 6 between patients receiving hematopoietic stem cell transplantation and HLA matched sibling donorsQ37146048
High-resolution patterns of meiotic recombination across the human major histocompatibility complexQ37202950
Novel HLA-DP region susceptibility loci associated with severe acute GvHD.Q37559942
SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based AssociationsQ38386637
HLA mismatching as a strategy to reduce relapse after alternative donor transplantationQ38783831
Multi-SNP analysis of MHC region: remarkable conservation of HLA-A1-B8-DR3 haplotypeQ40330077
A single high-resolution HLA mismatch has a similar adverse impact on the outcome of related hematopoietic stem cell transplantation as a single low-resolution HLA mismatchQ41104915
A T-cell epitope encoded by a subset of HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantationQ42611632
Nonpermissive HLA-DPB1 disparity is a significant independent risk factor for mortality after unrelated hematopoietic stem cell transplantationQ45172988
Genetic polymorphism related to monocyte-macrophage function is associated with graft-versus-host disease.Q45853292
A linkage disequilibrium map of the MHC region based on the analysis of 14 loci haplotypes in 50 French familiesQ47681972
HLA-DPB1 mismatch induces a graft-versus-leukemia effect without severe acute GVHD after single-unit umbilical cord blood transplantationQ50204017
Matching for the MICA-129 polymorphism is beneficial in unrelated hematopoietic stem cell transplantationQ50224813
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectsiblingQ31184
P304page(s)5396
P577publication date2018-03-29
P1433published inScientific ReportsQ2261792
P1476titleHidden genomic MHC disparity between HLA-matched sibling pairs in hematopoietic stem cell transplantation
P478volume8

Reverse relations

Q92404871Computational Analysis of HLA-presentation of Non-synonymous Recipient Mismatches Indicates Effect on the Risk of Chronic Graft-vs.-Host Disease After Allogeneic HSCTcites workP2860

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