Novel colchicine-site binders with a cyclohexanedione scaffold identified through a ligand-based virtual screening approach.

scientific article published on 9 May 2014

Novel colchicine-site binders with a cyclohexanedione scaffold identified through a ligand-based virtual screening approach. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/JM401939G
P698PubMed publication ID24773591

P50authorMaría-José CamarasaQ42258186
Eva-María PriegoQ43146435
Sam NoppenQ56385123
María Jésus Pérez PérezQ56811089
J. Fernando DíazQ57966649
Sandra LiekensQ78696639
María-Dolores CanelaQ114401437
P2093author name stringGonzalo Sáez-Calvo
P2860cites workSMILES, a chemical language and information system. 1. Introduction to methodology and encoding rulesQ28090714
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectvirtual screeningQ4112105
(S)-(−)-colchicineQ326224
P304page(s)3924-3938
P577publication date2014-05-09
P1433published inJournal of Medicinal ChemistryQ900316
P1476titleNovel colchicine-site binders with a cyclohexanedione scaffold identified through a ligand-based virtual screening approach.
P478volume57

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cites work (P2860)
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Q50700408A new four-component reaction involving the Michael addition and the Gewald reaction, leading to diverse biologically active 2-aminothiophenes.
Q27705273Antivascular and antitumor properties of the tubulin-binding chalcone TUB091
Q47750928Function and structure-based screening of compounds, peptides and proteins to identify drug candidates.
Q52361053High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.
Q35214924Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents
Q38913969Synthesis and Evaluation of Millepachine Amino Acid Prodrugs With Enhanced Solubility as Antitumor Agents
Q58880802Synthesis of Pironetin-Dumetorine Hybrids as Tubulin Binders

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