APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer.

scientific article published on 27 January 2018

APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.24357
P932PMC publication ID5837745
P698PubMed publication ID29545934

P50authorMarit OtterleiQ28718102
Siver Andreas MoestueQ42637173
Tone F. BathenQ61104171
Jana KimQ117273951
P2093author name stringSiri Bachke
Deborah K Hill
Morten B Rye
Nina-Beate Liabakk
Anala Nepal
Caroline K Søgaard
P2860cites workNucleotide excision repair is associated with the replisome and its efficiency depends on a direct interaction between XPA and PCNAQ21133901
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Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stressQ24338351
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The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cellsQ24599645
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Diffusion-weighted MRI for early detection and characterization of prostate cancer in the transgenic adenocarcinoma of the mouse prostate model.Q31021726
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Targeting proliferating cell nuclear antigen and its protein interactions induces apoptosis in multiple myeloma cellsQ34922853
Increased Anticancer Efficacy of Intravesical Mitomycin C Therapy when Combined with a PCNA Targeting PeptideQ35028770
Identification and validation of potential new biomarkers for prostate cancer diagnosis and prognosis using 2D-DIGE and MS.Q35033878
EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasisQ35190722
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Ly6E/K Signaling to TGFβ Promotes Breast Cancer Progression, Immune Escape, and Drug ResistanceQ37012226
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A functional analysis of PCNA-binding peptides derived from protein sequence, interaction screening and rational designQ37236371
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Taxane mechanisms of action: potential implications for treatment sequencing in metastatic castration-resistant prostate cancerQ38126220
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The Upregulation of PI3K/Akt and MAP Kinase Pathways is Associated with Resistance of Microtubule-Targeting Drugs in Prostate CancerQ38914271
NUSAP1 expression is upregulated by loss of RB1 in prostate cancer cellsQ38920403
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Dual PI3K/mTOR inhibitor NVP-BEZ235 sensitizes docetaxel in castration resistant prostate cancer.Q39108991
Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication ForkQ39117841
Clusterin is epigenetically regulated in prostate cancerQ39958114
Transforming growth factor β: A potential biomarker and therapeutic target of ventricular remodelingQ41593391
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P4510describes a project that useslimmaQ112236343
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectdocetaxelQ420436
P304page(s)11752-11766
P577publication date2018-01-27
P1433published inOncotargetQ1573155
P1476titleAPIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer.
P478volume9

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cites work (P2860)
Q58727488"Two hits - one stone"; increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling
Q60927734APIM-Mediated REV3L⁻PCNA Interaction Important for Error Free TLS Over UV-Induced DNA Lesions in Human Cells
Q90629773Additive effects of a small molecular PCNA inhibitor PCNA-I1S and DNA damaging agents on growth inhibition and DNA damage in prostate and lung cancer cells
Q92881732Helicase-Like Transcription Factor HLTF and E3 Ubiquitin Ligase SHPRH Confer DNA Damage Tolerance through Direct Interactions with Proliferating Cell Nuclear Antigen (PCNA)
Q64117242Knockdown of lncRNA MNX1-AS1 suppresses cell proliferation, migration, and invasion in prostate cancer
Q92540118Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy
Q98497959Ultrasound-Mediated Delivery of Chemotherapy into the Transgenic Adenocarcinoma of the Mouse Prostate Model

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