Specific Amyloid Binding of Polybasic Peptides In Vivo Is Retained by β-Sheet Conformers but Lost in the Disrupted Coil and All D-Amino Acid Variants.

scientific article published on 22 February 2017

Specific Amyloid Binding of Polybasic Peptides In Vivo Is Retained by β-Sheet Conformers but Lost in the Disrupted Coil and All D-Amino Acid Variants. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11307-017-1063-0
P932PMC publication ID5610100
P698PubMed publication ID28229334

P50authorRobert L. DonnellQ46728748
Jonathan S WallQ52679330
P2093author name stringTina Richey
Emily B Martin
Alan Stuckey
Stephen J Kennel
Angela Williams
Craig Wooliver
J Christopher Scott
P2860cites workI-TASSER server for protein 3D structure predictionQ21284202
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I-TASSER: a unified platform for automated protein structure and function predictionQ24605680
Systemic amyloidosisQ30251986
Dynamic PET and SPECT imaging with radioiodinated, amyloid-reactive peptide p5 in mice: a positive role for peptide dehalogenation.Q34216798
The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease.Q34412830
A binding-site barrier affects imaging efficiency of high affinity amyloid-reactive peptide radiotracers in vivoQ34764389
In vivo molecular imaging of peripheral amyloidosis using heparin-binding peptides.Q35180876
Preclinical Validation of the Heparin-Reactive Peptide p5+14 as a Molecular Imaging Agent for Visceral AmyloidosisQ35639988
SPECT imaging of peripheral amyloid in mice by targeting hyper-sulfated heparan sulfate proteoglycans with specific scFv antibodies.Q35656129
Transgenic mouse model of AA amyloidosisQ35786782
Comparative evaluation of p5+14 with SAP and peptide p5 by dual-energy SPECT imaging of mice with AA amyloidosis.Q36645348
Comparative analysis of peptide p5 and serum amyloid P component for imaging AA amyloid in mice using dual-isotope SPECT.Q36877784
Functional consequences of retro-inverso isomerization of a miniature protein inhibitor of the p53-MDM2 interactionQ37053063
Peptide p5 binds both heparinase-sensitive glycosaminoglycans and fibrils in patient-derived AL amyloid extractsQ37076423
Quantitative tomography of early-onset spontaneous AA amyloidosis in interleukin 6 transgenic miceQ37261989
Bioenergetic impact of tissue-specific regulation of iodothyronine deiodinases during nutritional imbalanceQ37830366
Strategic approaches to optimizing peptide ADME propertiesQ38264736
Somatostatin and somatostatin analogues: pharmacokinetics and pharmacodynamic effectsQ40623355
Secondary structure propensity and chirality of the amyloidophilic peptide p5 and its analogues impacts ligand binding - In vitro characterizationQ41682767
Development of the multiple sequence approximation within the AGADIR model of alpha-helix formation: comparison with Zimm-Bragg and Lifson-Roig formalisms.Q52267131
Simulation study of triple-energy-window scatter correction in combined Tl-201, Tc-99m SPECTQ72124995
Binding of a de novo designed peptide to specific glycosaminoglycansQ73039711
Amyloid-specific heparan sulfate from human liver and spleenQ73797107
Performance characterization of the Inveon preclinical small-animal PET/SPECT/CT system for multimodality imagingQ82864288
Importance of the spatial display of charged residues in heparin-peptide interactionsQ84836898
P433issue5
P304page(s)714-722
P577publication date2017-02-22
P1433published inMolecular Imaging and BiologyQ6895951
P1476titleSpecific Amyloid Binding of Polybasic Peptides In Vivo Is Retained by β-Sheet Conformers but Lost in the Disrupted Coil and All D-Amino Acid Variants.
P478volume19

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cites work (P2860)
Q41471564A Peptide-Fc Opsonin with Pan-Amyloid Reactivity
Q58098515Bifunctional amyloid-reactive peptide promotes binding of antibody 11-1F4 to diverse amyloid types and enhances therapeutic efficacy
Q47140227Evaluation of the effect of D-amino acid incorporation into amyloid-reactive peptides

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