scholarly article | Q13442814 |
P50 | author | Courtney C Hong | Q87742296 |
Eugenia Trushina | Q87870241 | ||
P2093 | author name string | Liang Zhang | |
Trace A Christensen | |||
Joseph F Poduslo | |||
Sergey Trushin | |||
Kyle G Howell | |||
Utkarsh Tripathi | |||
Rachel E Geroux | |||
P2860 | cites work | Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice | Q22242267 |
Alzheimer's Disease | Q22248111 | ||
A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline | Q22251083 | ||
The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility | Q24315540 | ||
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory | Q24645499 | ||
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts | Q24675729 | ||
Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease | Q27302961 | ||
Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease | Q27307877 | ||
Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration | Q27310252 | ||
Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal Neurons | Q27313482 | ||
Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons | Q27335309 | ||
Abeta, oxidative stress in Alzheimer disease: evidence based on proteomics studies | Q27693922 | ||
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1 | Q28118975 | ||
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models | Q28119018 | ||
Folding proteins in fatal ways | Q28235206 | ||
Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta | Q28239322 | ||
Mitochondrial trafficking in neurons | Q28291981 | ||
Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport | Q28512320 | ||
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro | Q28584697 | ||
Axonal transport and neurodegenerative disease: can we see the elephant? | Q28661055 | ||
Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death | Q28730589 | ||
Alzheimer's disease: Effects of β-amyloid on mitochondria | Q37785305 | ||
Amyloid-independent mechanisms in Alzheimer's disease pathogenesis | Q37808579 | ||
Amyloid precursor protein processing and Alzheimer's disease | Q37860317 | ||
The early events of Alzheimer's disease pathology: from mitochondrial dysfunction to BDNF axonal transport deficits | Q37972740 | ||
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes | Q37979641 | ||
Mitochondrial dynamics in neurodegeneration | Q38060435 | ||
In vitro oligomerization and fibrillogenesis of amyloid-beta peptides | Q38066087 | ||
Axonal transport deficits and neurodegenerative diseases | Q38077679 | ||
Toxic species in amyloid disorders: Oligomers or mature fibrils | Q38505323 | ||
Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks | Q38909227 | ||
Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research? | Q39149919 | ||
On the Pathogenesis of Alzheimer's Disease: The MAM Hypothesis | Q39155255 | ||
Ten Challenges of the Amyloid Hypothesis of Alzheimer's Disease | Q39357758 | ||
Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1. | Q39445726 | ||
Bioenergetic profile experiment using C2C12 myoblast cells | Q39614847 | ||
Tau inhibits anterograde axonal transport and perturbs stability in growing axonal neurites in part by displacing kinesin cargo: neurofilaments attenuate tau-mediated neurite instability | Q40052235 | ||
Serotonin stimulates mitochondrial transport in hippocampal neurons | Q40074582 | ||
In vivo targeting of antibody fragments to the nervous system for Alzheimer's disease immunotherapy and molecular imaging of amyloid plaques | Q40114596 | ||
Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons | Q40177850 | ||
Structural diversity of Alzheimer's disease amyloid-β dimers and their role in oligomerization and fibril formation. | Q41436984 | ||
Antioxidants Rescue Mitochondrial Transport in Differentiated Alzheimer's Disease Trans-Mitochondrial Cybrid Cells | Q41457391 | ||
The pattern and mechanism of mitochondrial transport in axons | Q41477217 | ||
Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure | Q41494079 | ||
Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein | Q41788034 | ||
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress | Q41830251 | ||
Selective contrast enhancement of individual Alzheimer's disease amyloid plaques using a polyamine and Gd-DOTA conjugated antibody fragment against fibrillar Abeta42 for magnetic resonance molecular imaging | Q42590594 | ||
Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits. | Q42773379 | ||
Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons. | Q42976903 | ||
Quantitative microplate-based respirometry with correction for oxygen diffusion | Q43069481 | ||
Familial Alzheimer's Disease Mutations within the Amyloid Precursor Protein Alter the Aggregation and Conformation of the Amyloid-β Peptide | Q44101761 | ||
Simultaneous analysis by capillary electrophoresis of five amyloid peptides as potential biomarkers of Alzheimer's disease. | Q44489714 | ||
Formation of toxic Abeta(1-40) fibrils on GM1 ganglioside-containing membranes mimicking lipid rafts: polymorphisms in Abeta(1-40) fibrils | Q46436538 | ||
Verification of the intermolecular parallel beta-sheet in E22K-Abeta42 aggregates by solid-state NMR using rotational resonance: implications for the supramolecular arrangement of the toxic conformer of Abeta42. | Q46441981 | ||
Amyloid-β peptide induces mitochondrial dysfunction by inhibition of preprotein maturation. | Q46844863 | ||
Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease | Q47714762 | ||
Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons. | Q48398341 | ||
Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model. | Q50632009 | ||
Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions. | Q51019981 | ||
Nerve growth factor signaling regulates motility and docking of axonal mitochondria. | Q51642532 | ||
Alzheimer's disease amyloid β-protein mutations and deletions that define neuronal binding/internalization as early stage nonfibrillar/fibrillar aggregates and late stage fibrils. | Q53328355 | ||
A new amyloid beta variant favoring oligomerization in Alzheimer's-type dementia. | Q53391715 | ||
Effect of pathogenic mutations on the structure and dynamics of Alzheimer's A beta 42-amyloid oligomers. | Q53406038 | ||
Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo | Q57274183 | ||
CNS Axons Globally Increase Axonal Transport after Peripheral Conditioning | Q58153947 | ||
Organelle motility and metabolism in axons vs dendrites of cultured hippocampal neurons | Q71354774 | ||
The Osaka FAD mutation E22Δ leads to the formation of a previously unknown type of amyloid β fibrils and modulates Aβ neurotoxicity | Q83607250 | ||
Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers | Q87242797 | ||
The Japanese Mutant Aβ (ΔE22-Aβ1−39) Forms Fibrils Instantaneously, with Low-Thioflavin T Fluorescence: Seeding of Wild-Type Aβ1−40into Atypical Fibrils by ΔE22-Aβ1−39 | Q29544432 | ||
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics | Q29614972 | ||
Intracellular amyloid-beta in Alzheimer's disease | Q29615626 | ||
Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases | Q29615646 | ||
Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline | Q30476347 | ||
β-Amyloid impairs axonal BDNF retrograde trafficking | Q30498160 | ||
Amyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons | Q30542949 | ||
Synaptic targeting by Alzheimer's-related amyloid beta oligomers. | Q33288786 | ||
Mechanism of neuronal versus endothelial cell uptake of Alzheimer's disease amyloid beta protein | Q33413066 | ||
Mitochondrial mislocalization underlies Abeta42-induced neuronal dysfunction in a Drosophila model of Alzheimer's disease | Q33519068 | ||
HH domain of Alzheimer's disease Abeta provides structural basis for neuronal binding in PC12 and mouse cortical/hippocampal neurons | Q33526300 | ||
Rates of β-amyloid accumulation are independent of hippocampal neurodegeneration | Q33581412 | ||
Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease | Q33614523 | ||
Preparation of fluorescently-labeled amyloid-beta peptide assemblies: the effect of fluorophore conjugation on structure and function | Q33682529 | ||
Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport | Q33700664 | ||
Inhibition of AMPA receptor trafficking at hippocampal synapses by beta-amyloid oligomers: the mitochondrial contribution | Q33784921 | ||
Surface plasmon resonance binding kinetics of Alzheimer's disease amyloid beta peptide-capturing and plaque-binding monoclonal antibodies | Q33944437 | ||
The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation | Q34088689 | ||
Amyloid β-protein aggregation produces highly reproducible kinetic data and occurs by a two-phase process | Q34332006 | ||
Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism | Q34346440 | ||
Targeting mitochondrial bioenergetics for Alzheimer's prevention and treatment | Q34407220 | ||
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes | Q34452028 | ||
The Alzheimer disease protective mutation A2T modulates kinetic and thermodynamic properties of amyloid-β (Aβ) aggregation | Q34467463 | ||
Alzheimer's disease beta-amyloid peptides are released in association with exosomes | Q34547007 | ||
Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation | Q34567280 | ||
Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons | Q34575798 | ||
Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons | Q34590202 | ||
Assessing mitochondrial dysfunction in cells. | Q34793639 | ||
Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration | Q34804911 | ||
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides | Q34854192 | ||
Bioenergetic function in cardiovascular cells: the importance of the reserve capacity and its biological regulation | Q34961101 | ||
Intracellular A-beta amyloid, a sign for worse things to come? | Q34995075 | ||
Fast axonal transport misregulation and Alzheimer's disease | Q34995098 | ||
Mitochondrial movement and positioning in axons: the role of growth factor signaling | Q35131142 | ||
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease | Q35532902 | ||
Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease | Q35689983 | ||
Toxicity of amyloid beta peptide: tales of calcium, mitochondria, and oxidative stress | Q35707277 | ||
Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's Disease | Q35733751 | ||
Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics | Q35737647 | ||
Cofilin aggregation blocks intracellular trafficking and induces synaptic loss in hippocampal neurons | Q35763182 | ||
Molecular pathways to neurodegeneration | Q35844771 | ||
Role of mitochondrial homeostasis and dynamics in Alzheimer's disease | Q35916588 | ||
A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade | Q35918740 | ||
A persistent stress response to impeded axonal transport leads to accumulation of amyloid-β in the endoplasmic reticulum, and is a probable cause of sporadic Alzheimer's disease | Q35997626 | ||
Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells | Q36152115 | ||
Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease | Q36196976 | ||
Amyloid β-Protein Assembly: Differential Effects of the Protective A2T Mutation and Recessive A2V Familial Alzheimer's Disease Mutation | Q36199818 | ||
The A673T mutation in the amyloid precursor protein reduces the production of β-amyloid protein from its β-carboxyl terminal fragment in cells | Q36247247 | ||
Mitochondria take center stage in aging and neurodegeneration | Q36264218 | ||
The axonal transport of mitochondria. | Q36321480 | ||
Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease | Q36348804 | ||
Comprehensive Method for Culturing Embryonic Dorsal Root Ganglion Neurons for Seahorse Extracellular Flux XF24 Analysis | Q36466105 | ||
Defective axonal transport in motor neuron disease | Q36723372 | ||
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae | Q36856671 | ||
β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1. | Q36910190 | ||
Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport | Q36935494 | ||
The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells | Q37150804 | ||
Amyloid β oligomers elicit mitochondrial transport defects and fragmentation in a time-dependent and pathway-specific manner | Q37185261 | ||
The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through Tau phosphorylation | Q37200468 | ||
Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease | Q37321251 | ||
Geniposide Alleviates Amyloid-Induced Synaptic Injury by Protecting Axonal Mitochondrial Trafficking | Q37604073 | ||
Axonal transport defects in neurodegenerative diseases | Q37614744 | ||
Control of mitochondrial transport and localization in neurons. | Q37652688 | ||
The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives | Q37656554 | ||
Increased acetylation of Peroxiredoxin1 by HDAC6 inhibition leads to recovery of Aβ-induced impaired axonal transport | Q37671409 | ||
The role of mitochondrial network dynamics in the pathogenesis of Charcot-Marie-Tooth disease. | Q37708107 | ||
Role of mitochondrial amyloid-beta in Alzheimer's disease | Q37750243 | ||
Mitochondrial biology in Alzheimer's disease pathogenesis. | Q37759167 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P304 | page(s) | 1-16 | |
P577 | publication date | 2018-03-02 | |
P1433 | published in | Neurobiology of Disease | Q15716606 |
P1476 | title | Differential effect of amyloid beta peptides on mitochondrial axonal trafficking depends on their state of aggregation and binding to the plasma membrane | |
P478 | volume | 114 |
Q92848737 | Beta-amyloid induces apoptosis of neuronal cells by inhibition of the Arg/N-end rule pathway proteolytic activity |
Q59137911 | High content organelle trafficking enables disease state profiling as powerful tool for disease modelling |
Q58599968 | Role of GTPases in the Regulation of Mitochondrial Dynamics in Alzheimer's Disease and CNS-Related Disorders |
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