The role of Next-Generation Sequencing in tumoral radiosensitivity prediction

scientific article published on 9 April 2017

The role of Next-Generation Sequencing in tumoral radiosensitivity prediction is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CTRO.2017.03.002
P932PMC publication ID5893518
P698PubMed publication ID29658008

P50authorJean-Emmanuel BibaultQ43379650
P2093author name stringIngeborg Tinhofer
P2860cites workA genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based studyQ39087110
A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicityQ39200585
Prediction of radiation sensitivity using a gene expression classifierQ40384787
Targeted next-generation sequencing of locally advanced squamous cell carcinomas of the head and neck reveals druggable targets for improving adjuvant chemoradiation.Q40784146
Exomics and immunogenics: Bridging mutational load and immune checkpoints efficacyQ41983246
A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1.Q42208433
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patientsQ43681440
Integration of a Radiosensitivity Molecular Signature Into the Assessment of Local Recurrence Risk in Breast CancerQ49885799
Limits to Personalized Cancer MedicineQ53768091
Perspective: The precision-oncology illusionQ57765633
Gain of oncogenic function of p53 mutants induces invasive phenotypes in human breast cancer cells by silencing CCN5/WISP-2Q81469203
Genetics and genomics of radiotherapy toxicity: towards predictionQ21183971
Mapping and quantifying mammalian transcriptomes by RNA-SeqQ22122035
A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasisQ24312492
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapyQ27824812
Prognostic significance of truncating TP53 mutations in head and neck squamous cell carcinomaQ27851637
TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.Q27851687
Sequencing technologies - the next generationQ27860568
Comprehensive genomic characterization of head and neck squamous cell carcinomasQ28256121
Genome-wide mapping of in vivo protein-DNA interactionsQ29547162
A framework for variation discovery and genotyping using next-generation DNA sequencing dataQ29547262
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1Q29614651
The mutational landscape of head and neck squamous cell carcinomaQ29614654
A rapid method for determining sequences in DNA by primed synthesis with DNA polymeraseQ29615980
TP53 mutations and survival in squamous-cell carcinoma of the head and neck.Q30366618
An Overview of the Analysis of Next Generation Sequencing DataQ34087270
A decade's perspective on DNA sequencing technologyQ34163657
Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis studyQ34240634
Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor typesQ34457638
A gene expression model of intrinsic tumor radiosensitivity: prediction of response and prognosis after chemoradiationQ34572724
Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomasQ35008028
Next-generation sequencing of RNA and DNA isolated from paired fresh-frozen and formalin-fixed paraffin-embedded samples of human cancer and normal tissueQ35176679
Differences Between Colon Cancer Primaries and Metastases Using a Molecular Assay for Tumor Radiation Sensitivity Suggest Implications for Potential Oligometastatic SBRT Patient SelectionQ35782954
Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing.Q35892011
Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical TrialsQ35998823
The radiosensitivity index predicts for overall survival in glioblastomaQ36544110
New Paradigms and Future Challenges in Radiation Oncology: An Update of Biological Targets and TechnologyQ37160539
Directed evolution of ionizing radiation resistance in Escherichia coliQ37301986
Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM.Q37705828
Next-generation sequencing and epigenomics research: a hammer in search of nails.Q37709045
Validation of a radiosensitivity molecular signature in breast cancer.Q37714313
Personalized radiation therapy and biomarker-driven treatment strategies: a systematic reviewQ38099763
Targeted next-generation sequencing identifies molecular subgroups in squamous cell carcinoma of the head and neck with distinct outcome after concurrent chemoradiationQ38378172
Emerging molecular networks common in ionizing radiation, immune and inflammatory responses by employing bioinformatics approachesQ38405769
Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort studyQ38431287
P304page(s)16-20
P577publication date2017-04-09
P1433published inClinical and Translational Radiation OncologyQ50817416
P1476titleThe role of Next-Generation Sequencing in tumoral radiosensitivity prediction
P478volume3

Reverse relations

cites work (P2860)
Q64086042Circulating Tumour Cells (CTC), Head and Neck Cancer and Radiotherapy; Future Perspectives
Q92255791Laser-driven radiation: Biomarkers for molecular imaging of high dose-rate effects

Search more.