Dissecting inherent intratumor heterogeneity in patient-derived glioblastoma culture models.

scientific article published on 6 January 2017

Dissecting inherent intratumor heterogeneity in patient-derived glioblastoma culture models. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NEUONC/NOW253
P932PMC publication ID5464448
P698PubMed publication ID28062830

P2093author name stringIchiro Nakano
E Antonio Chiocca
Bakhos A Tannous
Tracy T Batchelor
Hiroaki Wakimoto
Rami S Kantar
Jian Teng
Cintia Carla da Hora
Christian E Badr
P2860cites workPhenotype switching: tumor cell plasticity as a resistance mechanism and target for therapy.Q38260649
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cellsQ39004963
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An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma.Q42621989
Acidic extracellular microenvironment and cancerQ42850228
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Acid pH in tumors and its potential for therapeutic exploitationQ44056533
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Identification of a cancer stem cell in human brain tumorsQ28131688
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylationQ29614709
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastomaQ29615604
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell linesQ29615823
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesisQ29619677
Integrative genomic approaches identify IKBKE as a breast cancer oncogeneQ33287979
The transcriptional network for mesenchymal transformation of brain tumours.Q33572162
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.Q33725972
Real-time monitoring of nuclear factor kappaB activity in cultured cells and in animal models.Q33795121
MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastomaQ34119993
Glioblastoma stem-like cells give rise to tumour endothelium.Q34151507
Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells.Q34151513
Acidity generated by the tumor microenvironment drives local invasionQ34320819
Brain tumor cells in circulation are enriched for mesenchymal gene expressionQ34458631
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Acidic stress promotes a glioma stem cell phenotype.Q34985109
Heterogeneity maintenance in glioblastoma: a social networkQ35050894
Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells.Q35696355
Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.Q36884210
Triple bioluminescence imaging for in vivo monitoring of cellular processes.Q36968192
Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivoQ37217394
A secreted luciferase for ex vivo monitoring of in vivo processesQ37235465
Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma.Q37279893
Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectorsQ37447217
Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant gliomaQ37699420
Glioblastoma and other malignant gliomas: a clinical review.Q38160159
Brain mesenchymal stem cells: The other stem cells of the brain?Q38207598
P4510describes a project that usesImageJQ1659584
P433issue6
P921main subjectglioblastomaQ282142
heterogeneityQ928498
P304page(s)820-832
P577publication date2017-06-01
P1433published inNeuro-OncologyQ15724471
P1476titleDissecting inherent intratumor heterogeneity in patient-derived glioblastoma culture models.
P478volume19

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cites work (P2860)
Q64074404A TNF-NF-κB-STAT3 loop triggers resistance of glioma-stem-like cells to Smac mimetics while sensitizing to EZH2 inhibitors
Q47169542Current trends in mouse models of glioblastoma.
Q57048305Genetic Abnormalities, Clonal Evolution, and Cancer Stem Cells of Brain Tumors
Q89787572Glioma-Derived miRNA-Containing Extracellular Vesicles Induce Angiogenesis by Reprogramming Brain Endothelial Cells
Q59336125Integration of transcriptome and proteome profiles in glioblastoma: looking for the missing link
Q92669797Kinins in Glioblastoma Microenvironment
Q90419003Patient-Derived Glioma Models: From Patients to Dish to Animals
Q47988508Recycling drug screen repurposes hydroxyurea as a sensitizer of glioblastomas to temozolomide targeting de novo DNA synthesis, irrespective of molecular subtype.
Q64109506Stearoyl CoA Desaturase Is Essential for Regulation of Endoplasmic Reticulum Homeostasis and Tumor Growth in Glioblastoma Cancer Stem Cells
Q64066949Sustained NF-κB-STAT3 signaling promotes resistance to Smac mimetics in Glioma stem-like cells but creates a vulnerability to EZH2 inhibition
Q50327117Utility of Glioblastoma Patient-Derived Orthotopic Xenografts in Drug Discovery and Personalized Therapy

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