| scholarly article | Q13442814 |
| P50 | author | Katrin Zeilinger | Q56961667 |
| P2093 | author name string | Daniel Seehofer | |
| Fanny Knöspel | |||
| Georg Damm | |||
| Nora Freyer | |||
| Frank Schubert | |||
| Jennifer Foster Harris | |||
| Rashi Iyer | |||
| Selina Greuel | |||
| Florian Gerstmann | |||
| Lisa Storch | |||
| P2860 | cites work | Animal models of hepatotoxicity. | Q38596917 |
| Long-term microfluidic glucose and lactate monitoring in hepatic cell culture | Q38985244 | ||
| Development of 3D dynamic flow model of human liver and its application to prediction of metabolic clearance of 7-ethoxycoumarin | Q39051346 | ||
| Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity | Q39409174 | ||
| Hepatic organoids for microfluidic drug screening | Q40204531 | ||
| Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease | Q40770241 | ||
| Hepatic Differentiation of Human Induced Pluripotent Stem Cells in a Perfused Three-Dimensional Multicompartment Bioreactor. | Q40965254 | ||
| The Role of Microfluidics for Organ on Chip Simulations | Q41512399 | ||
| Long-term maintenance of a microfluidic 3D human liver sinusoid. | Q42390972 | ||
| Featured Article: Isolation, characterization, and cultivation of human hepatocytes and non-parenchymal liver cells | Q42430038 | ||
| On-Chip Construction of Liver Lobule-like Microtissue and Its Application for Adverse Drug Reaction Assay | Q42487207 | ||
| Long term cultures of primary human hepatocytes as an alternative to drug testing in animals. | Q43103482 | ||
| Hepatobiliary excretion of acetaminophen glutathione conjugate and its derivatives in transport-deficient (TR-) hyperbilirubinemic rats | Q44447163 | ||
| Serum lactic dehydrogenase in the differential diagnosis of acute hepatocellular injury. | Q44921578 | ||
| Human hepatocyte functions in a crossed hollow fiber membrane bioreactor | Q46137175 | ||
| Multiple mechanisms are involved in the biliary excretion of acetaminophen sulfate in the rat: role of Mrp2 and Bcrp1. | Q46463079 | ||
| Serum-free culture of primary human hepatocytes in a miniaturized hollow-fibre membrane bioreactor for pharmacological in vitro studies | Q46467026 | ||
| Oxidative stress triggers cytokinesis failure in hepatocytes upon isolation | Q46763677 | ||
| Evaluation of human hepatocytes cultured by three-dimensional spheroid systems for drug metabolism | Q47889610 | ||
| Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation | Q50336059 | ||
| Cowchock syndrome is associated with a mutation in apoptosis-inducing factor | Q24305311 | ||
| Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes | Q24311331 | ||
| Mechanisms of acetaminophen-induced liver necrosis | Q24629891 | ||
| Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method | Q25938999 | ||
| Experimental models of hepatotoxicity related to acute liver failure | Q26775293 | ||
| Regulation of immune responses by prostaglandin E2 | Q26849305 | ||
| Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition. | Q27863328 | ||
| To scale or not to scale: the principles of dose extrapolation | Q28751735 | ||
| Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro | Q30412693 | ||
| Glutathione S-transferase Omega 2 Genetic Polymorphism and Risk of Hepatic Failure that Lead to Liver Transplantation in Iranian Population | Q33871933 | ||
| Concordance of the toxicity of pharmaceuticals in humans and in animals | Q33921168 | ||
| Mechanisms of acetaminophen-induced cell death in primary human hepatocytes. | Q34225946 | ||
| In vitro zonation and toxicity in a hepatocyte bioreactor | Q34375235 | ||
| Synthesis of IL-6 by hepatocytes is a normal response to common hepatic stimuli | Q35157197 | ||
| In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System | Q35993451 | ||
| Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI. | Q36146271 | ||
| Intracellular signaling mechanisms of acetaminophen-induced liver cell death | Q36263962 | ||
| Biochemical diagnosis of liver disease | Q36264139 | ||
| Sinusoidal endothelial cells as an early target for hepatic toxicants. | Q36423693 | ||
| Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures. | Q36569873 | ||
| Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity | Q36652448 | ||
| Hepatocyte polarity | Q36972087 | ||
| Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. | Q37121662 | ||
| Apoptosis and necrosis in the liver | Q37403072 | ||
| A review of three-dimensional in vitro tissue models for drug discovery and transport studies | Q37763680 | ||
| Secondary necrosis: The natural outcome of the complete apoptotic program | Q37802938 | ||
| Protective effect of rosiglitazone against acetaminophen-induced acute liver injury is associated with down-regulation of hepatic NADPH oxidases. | Q51314868 | ||
| Microfluidics-based 3D cell culture models: Utility in novel drug discovery and delivery research. | Q51459366 | ||
| A liver-on-a-chip platform with bioprinted hepatic spheroids. | Q51472011 | ||
| A microfluidically perfused three dimensional human liver model. | Q51483766 | ||
| Association of acetaminophen hepatotoxicity with fasting and ethanol use. | Q51592407 | ||
| Protocol for Isolation of Primary Human Hepatocytes and Corresponding Major Populations of Non-parenchymal Liver Cells. | Q52853586 | ||
| Analysis of drug metabolism activities in a miniaturized liver cell bioreactor for use in pharmacological studies. | Q52887959 | ||
| Scaling down of a clinical three-dimensional perfusion multicompartment hollow fiber liver bioreactor developed for extracorporeal liver support to an analytical scale device useful for hepatic pharmacological in vitro studies. | Q52899422 | ||
| Measurement of cell death in Mammalian cells. | Q53182006 | ||
| Functionality Testing of Primary Hepatocytes in Culture by Measuring Urea Synthesis. | Q53581268 | ||
| Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2 | Q69624974 | ||
| Role of CYP2E1 in the hepatotoxicity of acetaminophen | Q71142786 | ||
| Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics | Q72927887 | ||
| The effect of omeprazole pretreatment on acetaminophen metabolism in rapid and slow metabolizers of S-mephenytoin | Q73562528 | ||
| Clinical utility of lactate dehydrogenase: a historical perspective | Q86548724 | ||
| Plasma paracetamol concentration at hospital presentation has a dose-dependent relationship with liver injury despite prompt treatment with intravenous acetylcysteine | Q89287172 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 1 | |
| P921 | main subject | bioreactor | Q864699 |
| hepatotoxicity | Q1349821 | ||
| P577 | publication date | 2018-03-15 | |
| P1433 | published in | Bioengineering | Q27727186 |
| P1476 | title | Microscale 3D Liver Bioreactor for In Vitro Hepatotoxicity Testing under Perfusion Conditions. | |
| P478 | volume | 5 |
| Q58788725 | Advances in Micro-Bioreactor Design for Organ Cell Studies |
| Q57175318 | Conceptual Design of Micro-Bioreactors and Organ-on-Chips for Studies of Cell Cultures |
| Q92261619 | Human-Derived Organ-on-a-Chip for Personalized Drug Development |
| Q92117313 | Integration of in vitro data from three dimensionally cultured HepaRG cells and physiologically based pharmacokinetic modeling for assessment of acetaminophen hepatotoxicity |
| Q64084088 | Metabolism of remimazolam in primary human hepatocytes during continuous long-term infusion in a 3-D bioreactor system |
Search more.