scholarly article | Q13442814 |
P50 | author | Thomas P. Zwaka | Q110729809 |
P2093 | author name string | James A Thomson | |
P2860 | cites work | Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells | Q40798287 |
Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture | Q40843384 | ||
Maintenance of pluripotential embryonic stem cells by stem cell selection | Q40909874 | ||
In vitro differentiation of transplantable neural precursors from human embryonic stem cells | Q43814659 | ||
Behavioral and neurochemical evaluation of a transgenic mouse model of Lesch-Nyhan syndrome. | Q52250356 | ||
MHC class I expression in mice lacking the proteasome subunit LMP-7 | Q57198383 | ||
Targetted correction of a mutant HPRT gene in mouse embryonic stem cells | Q59085795 | ||
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells | Q24616059 | ||
Establishment in culture of pluripotential cells from mouse embryos | Q27860625 | ||
Embryonic stem cell lines derived from human blastocysts | Q27861010 | ||
Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination | Q28286762 | ||
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells | Q28590205 | ||
Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells | Q29614545 | ||
Feeder-free growth of undifferentiated human embryonic stem cells | Q34093315 | ||
Manipulating the mammalian genome by homologous recombination | Q34311686 | ||
Oct-4: gatekeeper in the beginnings of mammalian development. | Q34313833 | ||
HPRT mutations in humans: biomarkers for mechanistic studies | Q34416540 | ||
Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. | Q35226497 | ||
Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy | Q40738121 | ||
Selection of ventricular-like cardiomyocytes from ES cells in vitro | Q40782917 | ||
P4510 | describes a project that uses | H1 Oct4-EGFP | Q54871906 |
P433 | issue | 3 | |
P921 | main subject | human embryonic stem cell | Q59626782 |
cell line | Q21014462 | ||
P304 | page(s) | 319-321 | |
P577 | publication date | 2003-02-10 | |
P1433 | published in | Nature Biotechnology | Q1893837 |
P1476 | title | Homologous recombination in human embryonic stem cells. | |
P478 | volume | 21 |
Q26741371 | A Broad Overview and Review of CRISPR-Cas Technology and Stem Cells |
Q37273975 | A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells |
Q26770097 | A Dishful of a Troubled Mind: Induced Pluripotent Stem Cells in Psychiatric Research |
Q36168698 | A UTF1-based selection system for stable homogeneously pluripotent human embryonic stem cell cultures |
Q36682196 | A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies |
Q37596293 | A cut above the rest: targeted genome editing technologies in human pluripotent stem cells |
Q39887814 | A fluidic device to study directional angiogenesis in complex tissue and organ culture models |
Q35510498 | A genome-wide map of adeno-associated virus-mediated human gene targeting |
Q39618673 | A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity |
Q40143374 | A method for genetic modification of human embryonic stem cells using electroporation |
Q36633207 | A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening |
Q40203046 | A novel platform to enable the high-throughput derivation and characterization of feeder-free human iPSCs |
Q50646033 | A protocol for constructing gene targeting vectors: generating knockout mice for the cadherin family and beyond. |
Q42768213 | A simple and efficient system for regulating gene expression in human pluripotent stem cells and derivatives |
Q44968393 | A single EBV-based vector for stable episomal maintenance and expression of GFP in human embryonic stem cells. |
Q37340637 | A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells |
Q42333586 | A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells |
Q92900894 | A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology |
Q26774824 | ALS Patient Stem Cells for Unveiling Disease Signatures of Motoneuron Susceptibility: Perspectives on the Deadly Mitochondria, ER Stress and Calcium Triad |
Q33578349 | Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells. |
Q41643889 | Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells |
Q46570832 | An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells |
Q37678874 | Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein. |
Q35647378 | Averting abnormal inheritance: potential of gene therapy and preimplantation diagnosis |
Q34037858 | Back to the future: how human induced pluripotent stem cells will transform regenerative medicine |
Q41523233 | Background intensity correction for terabyte-sized time-lapse images |
Q36834586 | Building blood vessels--stem cell models in vascular biology |
Q41125370 | CMD kinetics and regenerative medicine |
Q47159163 | CRISPR/Cas-Mediated Knockin in Human Pluripotent Stem Cells |
Q47142507 | CRISPR/Cas9-Mediated Mutagenesis of Human Pluripotent Stem Cells in Defined Xeno-Free E8 Medium. |
Q47104635 | CRISPR/Cas9-assisted gRNA-free one-step genome editing with no sequence limitations and improved targeting efficiency. |
Q39294371 | CRISPR/Cas9: at the cutting edge of hepatology. |
Q37922212 | Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges |
Q38041270 | Cardiac repair and restoration using human embryonic stem cells |
Q36672119 | Cell replacement therapy and the evasion of destructive immunity |
Q89900510 | Cell surface GRP78 promotes stemness in normal and neoplastic cells |
Q35781209 | Cell therapy using human embryonic stem cells |
Q24615515 | Cell-based therapy for neural disorders--anticipating challenges |
Q36267224 | Cellular genetic therapy. |
Q36992604 | Cftr gene targeting in mouse embryonic stem cells mediated by Small Fragment Homologous Replacement (SFHR) |
Q36825868 | Challenges and approaches to the culture of pluripotent human embryonic stem cells |
Q36436582 | Challenges and strategies for generating therapeutic patient-specific hemangioblasts and hematopoietic stem cells from human pluripotent stem cells |
Q46513700 | Characterization and evaluation of human embryonic stem cells |
Q24797270 | Chipping away at 'stemness' |
Q33922429 | Chromosomal position effects on AAV-mediated gene targeting |
Q42223765 | Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells |
Q52728997 | Combined Ectopic Expression of Homologous Recombination Factors Promotes Embryonic Stem Cell Differentiation. |
Q38755883 | Combining Induced Pluripotent Stem Cells and Genome Editing Technologies for Clinical Applications |
Q55544139 | Combining Induced Pluripotent Stem Cells and Genome Editing Technologies for Clinical Applications. |
Q38765066 | Combining Single Strand Oligodeoxynucleotides and CRISPR/Cas9 to Correct Gene Mutations in β-Thalassemia-induced Pluripotent Stem Cells |
Q37872274 | Concise review: putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells |
Q52364906 | Conditional Manipulation of Gene Function in Human Cells with Optimized Inducible shRNA. |
Q34016088 | Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectors |
Q33570136 | Cre recombination-mediated cassette exchange for building versatile transgenic human embryonic stem cells lines |
Q24803689 | Creation of non-human primate neurogenetic disease models by gene targeting and nuclear transfer |
Q47604078 | Current science of regenerative medicine with stem cells |
Q34067230 | Custom-designed zinc finger nucleases: what is next? |
Q80346230 | Customized human embryonic stem cells |
Q37629987 | Deciphering Rett syndrome with mouse genetics, epigenomics, and human neurons |
Q35140726 | Deconstructing pancreas development to reconstruct human islets from pluripotent stem cells |
Q36165381 | Defining Conditions for Sustaining Epiblast Pluripotence Enables Direct Induction of Clinically-Suitable Human Myocardial Grafts from Biologics-Free Human Embryonic Stem Cells |
Q24803706 | Derivation and characterization of monkey embryonic stem cells |
Q40196513 | Derivation and characterization of three new Spanish human embryonic stem cell lines (VAL -3 -4 -5) on human feeder and in serum-free conditions. |
Q56529935 | Derivation and genetic modification of embryonic stem cells from disease-model inbred rat strains |
Q36385105 | Derivation of clinical-grade human embryonic stem cells. |
Q39480684 | Derivation of genetically modified human pluripotent stem cells with integrated transgenes at unique mapped genomic sites |
Q37031898 | Derive and conquer: sourcing and differentiating stem cells for therapeutic applications. |
Q30476562 | Development of functional human embryonic stem cell-derived neurons in mouse brain |
Q36225114 | Differentiation pathways in human embryonic stem cell-derived cardiomyocytes |
Q24796383 | Directed neuronal differentiation of human embryonic stem cells |
Q37851348 | Disease correction the iPSC way: advances in iPSC-based therapy. |
Q30489278 | Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. |
Q83071327 | Double knockouts in human embryonic stem cells |
Q44140013 | Editorial: Our top 10 developments in stem cell biology over the last 30 years |
Q40982138 | Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus |
Q37274503 | Efficient CRISPR/Cas9-Mediated Versatile, Predictable, and Donor-Free Gene Knockout in Human Pluripotent Stem Cells |
Q35874234 | Efficient Generation of Human Embryonic Stem Cell-Derived Corneal Endothelial Cells by Directed Differentiation |
Q35749996 | Efficient and accurate homologous recombination in hESCs and hiPSCs using helper-dependent adenoviral vectors |
Q34109867 | Efficient culturing and genetic manipulation of human pluripotent stem cells |
Q36138514 | Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines |
Q38518500 | Efficient designer nuclease-based homologous recombination enables direct PCR screening for footprintless targeted human pluripotent stem cells |
Q33769623 | Efficient gene targeting by homologous recombination in rat embryonic stem cells |
Q45858903 | Efficient genetic modification of cynomolgus monkey embryonic stem cells with lentiviral vectors |
Q34037839 | Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis |
Q33783227 | Efficient integration of transgenes into a defined locus in human embryonic stem cells |
Q85821747 | Efficient p53 gene targeting by homologous recombination in rat-induced pluripotent stem cells |
Q37655265 | Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage |
Q35198414 | Efficient recombinase-mediated cassette exchange at the AAVS1 locus in human embryonic stem cells using baculoviral vectors |
Q29622846 | Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases |
Q34135224 | Efficient, high-throughput transfection of human embryonic stem cells |
Q79357529 | Electroporation of cynomolgus monkey embryonic stem cells |
Q38034476 | Embryonic and induced pluripotent stem cell differentiation as a tool in neurobiology |
Q40422136 | Embryonic stem cell models of CAG repeat disease |
Q36672254 | Embryonic stem cell technology: applications and uses in functional genomic studies |
Q35985279 | Embryonic stem cells and islet replacement in diabetes mellitus |
Q35621391 | Embryonic stem cells in drug discovery |
Q37111916 | Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells. |
Q35931459 | Engineering Human Stem Cell Lines with Inducible Gene Knockout using CRISPR/Cas9 |
Q33930075 | Engineering of human pluripotent stem cells by AAV-mediated gene targeting |
Q24657199 | Engineering tissue from human embryonic stem cells |
Q35029331 | Enhanced transfection efficiency of human embryonic stem cells by the incorporation of DNA liposomes in extracellular matrix |
Q38542079 | Enrichment of G2/M cell cycle phase in human pluripotent stem cells enhances HDR-mediated gene repair with customizable endonucleases |
Q88219257 | Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas |
Q36148761 | Evaluating Electroporation and Lipofectamine Approaches for Transient and Stable Transgene Expressions in Human Fibroblasts and Embryonic Stem Cells |
Q37710740 | Fast and efficient multitransgenic modification of human pluripotent stem cells. |
Q47363760 | Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification |
Q36922762 | Find and replace: editing human genome in pluripotent stem cells |
Q33750568 | Four decades of leading-edge research in the reproductive and developmental sciences: the Infant Primate Research Laboratory at the University of Washington National Primate Research Center |
Q38592859 | From Genomics to Gene Therapy: Induced Pluripotent Stem Cells Meet Genome Editing |
Q37037834 | Functional analysis of various promoters in lentiviral vectors at different stages of in vitro differentiation of mouse embryonic stem cells. |
Q24791385 | Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline |
Q33930103 | Gene correction in human embryonic and induced pluripotent stem cells: promises and challenges ahead |
Q38852141 | Gene correction in patient-specific iPSCs for therapy development and disease modeling |
Q29014419 | Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery |
Q37089250 | Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors |
Q33325792 | Gene targeting in adult rhesus macaque fibroblasts. |
Q37287210 | Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells |
Q37857741 | Gene-manipulated embryonic stem cells for rat transgenesis |
Q38865593 | Generation of Isogenic Human iPS Cell Line Precisely Corrected by Genome Editing Using the CRISPR/Cas9 System |
Q39923037 | Generation of T lineage cells from human embryonic stem cells in a feeder free system |
Q34423562 | Generation of a drug-inducible reporter system to study cell reprogramming in human cells |
Q37291177 | Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system |
Q36293910 | Generation, culture, and differentiation of human embryonic stem cells for therapeutic applications |
Q34175757 | Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy. |
Q39303125 | Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells |
Q38170509 | Genetic correction using engineered nucleases for gene therapy applications |
Q29619830 | Genetic engineering of human pluripotent cells using TALE nucleases |
Q46242018 | Genetic manipulation of human induced pluripotent stem cells |
Q37024721 | Genetic modification of human embryonic stem cells |
Q33602474 | Genetic recombination pathways and their application for genome modification of human embryonic stem cells |
Q81465001 | Genetic selection of cardiomyocytes from human embryonic stem cells |
Q42157982 | Genome Editing and Directed Differentiation of hPSCs for Interrogating Lineage Determinants in Human Pancreatic Development. |
Q50941156 | Genome Editing in Human Pluripotent Stem Cells. |
Q38691263 | Genome Editing in Human Pluripotent Stem Cells: Approaches, Pitfalls, and Solutions |
Q54981587 | Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity. |
Q38113338 | Genome editing of human pluripotent stem cells to generate human cellular disease models |
Q34437293 | Genomic editing tools to model human diseases with isogenic pluripotent stem cells |
Q36417323 | Gold nanoparticles electroporation enhanced polyplex delivery to mammalian cells |
Q42934873 | H1 and H9 human embryonic stem cell lines are heterozygous for the ABO locus |
Q35847904 | Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development |
Q34213428 | High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents. |
Q37347808 | High-density distributed electrode network, a multi-functional electroporation method for delivery of molecules of different sizes. |
Q58708467 | Highly efficient genome editing via CRISPR-Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression |
Q36893512 | Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors |
Q55071387 | Homologous recombination efficiency enhanced by inhibition of MEK and GSK3β. |
Q37925146 | Homologous recombination in human embryonic stem cells: a tool for advancing cell therapy and understanding and treating human disease |
Q24310167 | Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages |
Q36382854 | Human Induced Pluripotent Stem Cell NEUROG2 Dual Knockin Reporter Lines Generated by the CRISPR/Cas9 System |
Q34278634 | Human cloning: can it be made safe? |
Q47576212 | Human embryonic stem cell derivation: from the IVF perspective to therapeutic applications |
Q38089145 | Human embryonic stem cell-derived cardiomyocytes: drug discovery and safety pharmacology |
Q36759016 | Human embryonic stem cells and gene therapy |
Q36545627 | Human embryonic stem cells as a powerful tool for studying human embryogenesis |
Q39734835 | Human embryonic stem cells carrying mutations for severe genetic disorders |
Q36745156 | Human embryonic stem cells for brain repair? |
Q37110246 | Human embryonic stem cells: a potential source of transplantable neural progenitor cells |
Q36672098 | Human embryonic stem cells: an in vitro model to study mechanisms controlling pluripotency in early mammalian development |
Q36309574 | Human embryonic stem cells: possibilities for human cell transplantation. |
Q26750393 | Human induced pluripotent stem cells for monogenic disease modelling and therapy |
Q34325210 | Human pluripotent stem cells: an emerging model in developmental biology. |
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Q34718115 | Identification and targeting of the ROSA26 locus in human embryonic stem cells. |
Q35953282 | Immunogenicity of human embryonic stem cells: can we achieve tolerance? |
Q64962189 | Improved Transfection Efficiency and Metabolic Activity in Human Embryonic Stem Cell Using Non-Enzymatic Method. |
Q39994756 | Improved genetic manipulation of human embryonic stem cells |
Q35775664 | In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases |
Q38013733 | In vitro uses of human pluripotent stem cell-derived cardiomyocytes. |
Q37254949 | In vitro- and in vivo-induced transgene expression in human embryonic stem cells and derivatives |
Q33647732 | In vivo selection of human embryonic stem cell-derived cells expressing methotrexate-resistant dihydrofolate reductase |
Q34525438 | Induced Pluripotent Stem Cells Meet Genome Editing |
Q94527397 | Induced Pluripotent Stem Cells: Reprogramming Platforms and Applications in Cell Replacement Therapy |
Q27860597 | Induced pluripotent stem cell lines derived from human somatic cells |
Q39856747 | Induced pluripotent stem cells: opportunities as research and development tools in 21st century drug discovery |
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Q45882848 | Integration of functional bacterial artificial chromosomes into human cord blood-derived multipotent stem cells. |
Q33558379 | Integration-defective lentiviral vector mediates efficient gene editing through homology-directed repair in human embryonic stem cells |
Q34431170 | Investigating human disease using stem cell models |
Q40139315 | LINE-1 retrotransposition in human embryonic stem cells |
Q36048565 | Large-scale time-lapse microscopy of Oct4 expression in human embryonic stem cell colonies |
Q37989402 | Lentiviral vectors and cardiovascular diseases: a genetic tool for manipulating cardiomyocyte differentiation and function |
Q40288697 | Lentiviral vectors harboring a dual-gene system allow high and homogeneous transgene expression in selected polyclonal human embryonic stem cells |
Q37371510 | Light-sheet Bayesian microscopy enables deep-cell super-resolution imaging of heterochromatin in live human embryonic stem cells |
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Q34267729 | Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions |
Q28593404 | Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity |
Q36945218 | Minireview: Genome Editing of Human Pluripotent Stem Cells for Modeling Metabolic Disease. |
Q37290586 | Modeling epilepsy with pluripotent human cells |
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Q40339136 | Normal collagen and bone production by gene-targeted human osteogenesis imperfecta iPSCs |
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