Intercentrosomal angular separation during mitosis plays a crucial role for maintaining spindle stability.

scientific article published on 28 October 2015

Intercentrosomal angular separation during mitosis plays a crucial role for maintaining spindle stability. is …
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scholarly articleQ13442814

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P819ADS bibcode2015PhRvE..92d2714S
P356DOI10.1103/PHYSREVE.92.042714
P8608Fatcat IDrelease_zgtdlfplqfhclodxczich3cxam
P698PubMed publication ID26565279

P50authorSabyasachi SutradharQ59217991
P2093author name stringR Paul
S Basu
P2860cites workFunctional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interferenceQ24300469
Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis.Q24329251
Monastrol inhibition of the mitotic kinesin Eg5.Q24540254
The human chromokinesin Kid is a plus end-directed microtubule-based motorQ24550989
Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesisQ24557528
Dynamic instability of microtubules as an efficient way to search in spaceQ24562817
Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindleQ24562852
Cell mechanics and the cytoskeletonQ24601132
Towards a quantitative understanding of mitotic spindle assembly and mechanicsQ24633928
The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindlesQ24670581
Opposing motor activities are required for the organization of the mammalian mitotic spindle poleQ24670991
Motile kinetochores and polar ejection forces dictate chromosome position on the vertebrate mitotic spindleQ24673532
Kinetochores capture astral microtubules during chromosome attachment to the mitotic spindle: direct visualization in live newt lung cellsQ24678769
The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindlesQ24685481
Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.Q24685871
Chromosomes can congress to the metaphase plate before biorientationQ27332199
EB1 recognizes the nucleotide state of tubulin in the microtubule latticeQ27338127
Minus-end-directed Kinesin-14 motors align antiparallel microtubules to control metaphase spindle lengthQ27935370
CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignmentQ28115655
Xkid, a chromokinesin required for chromosome alignment on the metaphase plateQ28144993
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Microtubule movements on the arms of mitotic chromosomes: polar ejection forces quantified in vitroQ30476206
Mammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashionQ30477500
Kinesin 5-independent poleward flux of kinetochore microtubules in PtK1 cellsQ30480390
Kinesin-5-dependent poleward flux and spindle length control in Drosophila embryo mitosisQ30486464
The distribution of polar ejection forces determines the amplitude of chromosome directional instabilityQ30488889
Computer simulations predict that chromosome movements and rotations accelerate mitotic spindle assembly without compromising accuracyQ30490349
Kinesin-5 acts as a brake in anaphase spindle elongationQ30491649
Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formationQ30528108
Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryoQ30654911
Model for anaphase B: role of three mitotic motors in a switch from poleward flux to spindle elongationQ30835545
Prometaphase spindle maintenance by an antagonistic motor-dependent force balance made robust by a disassembling lamin-B envelopeQ33616483
Molecular architecture of a kinetochore-microtubule attachment siteQ33839309
Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryosQ33880076
Microtubule motors in mitosisQ34036578
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Mitosis: a history of divisionQ34123562
A force balance model of early spindle pole separation in Drosophila embryos.Q34180288
Beyond self-assembly: from microtubules to morphogenesisQ34181655
The functional antagonism between Eg5 and dynein in spindle bipolarization is not compatible with a simple push-pull modelQ34290255
Microtubules orient the mitotic spindle in yeast through dynein-dependent interactions with the cell cortex.Q34434485
Budding yeast kinetochore proteins, Chl4 and Ctf19, are required to maintain SPB-centromere proximity during G1 and late anaphaseQ35202944
A driving and coupling "Pac-Man" mechanism for chromosome poleward translocation in anaphase A.Q35214606
Eg5 steps it up!Q35253269
Timing of centrosome separation is important for accurate chromosome segregationQ35712127
The spatial arrangement of chromosomes during prometaphase facilitates spindle assemblyQ35793140
Mechanisms and molecules of the mitotic spindleQ35893361
Kinetochore-spindle microtubule interactions during mitosisQ36015464
MCAK facilitates chromosome movement by promoting kinetochore microtubule turnoverQ36176571
Oscillatory movements of monooriented chromosomes and their position relative to the spindle pole result from the ejection properties of the aster and half-spindleQ36213174
Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrixQ36294036
The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindlesQ36322575
The kinesin-related protein, HSET, opposes the activity of Eg5 and cross-links microtubules in the mammalian mitotic spindleQ36326080
Chromosome motion during attachment to the vertebrate spindle: initial saltatory-like behavior of chromosomes and quantitative analysis of force production by nascent kinetochore fibersQ36529708
Interpolar spindle microtubules in PTK cellsQ36534704
Dynein antagonizes eg5 by crosslinking and sliding antiparallel microtubulesQ37440564
Control of mitotic spindle lengthQ37770247
End-binding proteins and Ase1/PRC1 define local functionality of structurally distinct parts of the microtubule cytoskeleton.Q38055967
Mitotic spindle multipolarity without centrosome amplification.Q38219034
Polo-like kinases: structural variations lead to multiple functionsQ38222354
Kinetics and motility of the Eg5 microtubule motorQ38361472
Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly.Q39914545
Kinetochore dynein generates a poleward pulling force to facilitate congression and full chromosome alignmentQ40097772
Genetic analysis of the mitotic spindleQ41291153
The bimC family of kinesins: essential bipolar mitotic motors driving centrosome separationQ41575138
Computer simulations reveal motor properties generating stable antiparallel microtubule interactionsQ42917433
Chromosome elasticity and mitotic polar ejection force measured in living Drosophila embryos by four-dimensional microscopy-based motion analysisQ44039726
Efficient chromosome capture requires a bias in the 'search-and-capture' process during mitotic-spindle assemblyQ46745381
Diffusible crosslinkers generate directed forces in microtubule networksQ50438329
Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells.Q52187841
Disruption of microtubule assembly and spindle formation as a mechanism for the induction of aneuploid cells by sodium arsenite and vanadium pentoxide.Q52526317
Active force generation in cross-linked filament bundles without motor proteins.Q53275653
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)042714
P577publication date2015-10-28
P1433published inPhysical Review EQ2128181
P1476titleIntercentrosomal angular separation during mitosis plays a crucial role for maintaining spindle stability
P478volume92