Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus. (scientific article published on 4 May 2015)

High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions

Q21092448

TRIM39 is a MOAP-1-binding protein that stabilizes MOAP-1 through inhibition of its poly-ubiquitination process

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A second lineage of mammalian major histocompatibility complex class I genes

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Structure of an archaeal homolog of the human protein complex Rpp21-Rpp29 that is a key core component for the assembly of active ribonuclease P

Q27652546

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

Q28236839

Recent advances in the genetics of autoimmune disease

Q28238782

Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX

Q28265206

Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity

Q28505683

Multiple hematopoietic defects and delayed globin switching in Ikaros null mice

Q28510404

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

Q28924381

Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy

Q28943554

Identification of two independent risk factors for lupus within the MHC in United Kingdom families

Q30837981

Impaired differentiation and cytotoxicity of natural killer cells in systemic lupus erythematosus

Q33384708

Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome

Q33388122

Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus

Q33769697

Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis

Q33836248

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus

Q34064253

Molecular genetics of cutaneous lupus erythematosus

Q34216223

Functional relevance for associations between genetic variants and systemic lupus erythematosus

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Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

Q34574913

Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study

Q35489210

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study

Q35877841

Transancestral mapping of the MHC region in systemic lupus erythematosus identifies new independent and interacting loci at MSH5, HLA-DPB1 and HLA-G

Q35896644

The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1.

Q35925284

TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE.

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The genetics of lupus: a functional perspective

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Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

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Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans

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A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails

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Cutaneous lupus erythematosus: understanding of clinical features, genetic basis, and pathobiology of disease guides therapeutic strategies

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Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus

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Taming lupus-a new understanding of pathogenesis is leading to clinical advances

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Unique contribution of IRF-5-Ikaros axis to the B-cell IgG2a response

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Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches.

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Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice.

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Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity

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STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus

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Pathogenesis of cutaneous lupus erythematosus

Q37168011

Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

Q37498799

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

Q37567071

Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population

Q37950997

Ikaros and tumor suppression in acute lymphoblastic leukemia

Q37965798

Aicardi-Goutières syndrome: a model disease for systemic autoimmunity

Q38115813

Photosensitivity, apoptosis, and cytokines in the pathogenesis of lupus erythematosus: a critical review.

Q38178160

The classification and diagnosis of cutaneous lupus erythematosus

Q38184196

Role of the MICA polymorphism in systemic lupus erythematosus.

Q39518838

Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms are associated with discoid and subacute cutaneous lupus erythematosus

Q43275833

HLA class II, MICA and PRL gene polymorphisms: the common contribution to the systemic lupus erythematosus development in Czech population.

Q45171706

TRIM39R, but not TRIM39B, regulates type I interferon response

Q46134720

Apoptotic signal molecules in skin biopsies of cutaneous lupus erythematosus: analysis using tissue microarray.

Q53088477

Lupus erythematosus tumidus is a separate subtype of cutaneous lupus erythematosus.

Q53188386

Systemic lupus erythematosus.

Q53202066

Clinical and laboratory characteristics of Finnish lupus erythematosus patients with cutaneous manifestations.

Q53746240

P4510

describes a project that uses

genome-wide association study

Q1098876

P433

issue

P921

main subject

genome-wide association study

Q1098876

susceptibility locus

Q62091149

P304

page(s)

510-515

P577

publication date

2015-05-04

P1433

published in

Experimental Dermatology

Q15749509

P1476

title

Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus.

P478

volume

Reverse relations

cites work (P2860)

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Q92535243	Cutaneous lupus erythematosus: new insights into pathogenesis and therapeutic strategies
Q38857518	Cutaneous lupus erythematosus: updates on pathogenesis and associations with systemic lupus
Q31102783	Early discoid lupus erythematosus protects against renal disease in patients with systemic lupus erythematosus: longitudinal data from a large Latin American cohort
Q64100517	Exploring Impact of Rare Variation in Systemic Lupus Erythematosus by a Genome Wide Imputation Approach
Q47323135	Genetic association study of systemic lupus erythematosus and disease subphenotypes in European populations.
Q38457307	Genome-wide differential expression reveals candidate genes involved in the pathogenesis of lupus and lupus nephritis
Q38888712	Immunogenetics of cutaneous lupus erythematosus
Q104459276	Nasopharyngeal carcinoma MHC region deep sequencing identifies HLA and novel non-HLA TRIM31 and TRIM39 loci
Q90479728	Selective Janus Kinase 1 Inhibition Is a Promising Therapeutic Approach for Lupus Erythematosus Skin Lesions
Q38903954	Spleen tyrosine kinase (SYK) is a potential target for the treatment of cutaneous lupus erythematosus patients
Q38850089	Therapeutic options for cutaneous lupus erythematosus: recent advances and future prospects