Arctigenin Protects against Lipopolysaccharide-Induced Pulmonary Oxidative Stress and Inflammation in a Mouse Model via Suppression of MAPK, HO-1, and iNOS Signaling.

scientific article published in August 2015

Arctigenin Protects against Lipopolysaccharide-Induced Pulmonary Oxidative Stress and Inflammation in a Mouse Model via Suppression of MAPK, HO-1, and iNOS Signaling. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10753-015-0115-3
P698PubMed publication ID25616905

P2093author name stringXian-ben Liu
Bao-xia He
Wen-zhou Zhang
Zheng-kui Jiang
P2860cites workHuman multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-α-induced protein 6Q24302245
Novel strategy for treatment of Japanese encephalitis using arctigenin, a plant lignanQ28266442
Andrographolide protects against LPS-induced acute lung injury by inactivation of NF-κBQ28486454
Oxidants, nitrosants, and the lungQ33181197
Effect of radix paeoniae rubra on expression of p38 MAPK/iNOS/HO-1 in rats with lipopolysaccharide-induced acute lung injury.Q33301770
Etanercept attenuates myocardial ischemia/reperfusion injury by decreasing inflammation and oxidative stressQ34258212
Regulatory effects of iNOS on acute lung inflammatory responses in miceQ35843243
Critical role for CCAAT/enhancer-binding protein β in immune complex-induced acute lung injuryQ36106598
Resolution of experimental lung injury by monocyte-derived inducible nitric oxide synthaseQ36179625
Acute lung injury reviewQ37472720
Acute respiratory distress syndrome: an overview for physician assistantsQ38143995
Isotetrandrine protects against lipopolysaccharide-induced acute lung injury by suppression of mitogen-activated protein kinase and nuclear factor-kappa B.Q38170725
Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits MAP kinases and AP-1 activation via potent MKK inhibition: the role in TNF-alpha inhibitionQ38337692
Vicious inducible nitric oxide synthase-mitochondrial reactive oxygen species cycle accelerates inflammatory response and causes liver injury in rats.Q38943179
α-Dihydroxychalcone-glycoside (α-DHC) isolated from the heartwood of Pterocarpus marsupium inhibits LPS induced MAPK activation and up regulates HO-1 expression in murine RAW 264.7 macrophageQ39010953
Arctigenin, a dietary phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation.Q39076620
Arctigenin promotes degradation of inducible nitric oxide synthase through CHIP-associated proteasome pathway and suppresses its enzyme activityQ39318436
Arctigenin inhibits lipopolysaccharide-induced iNOS expression in RAW264.7 cells through suppressing JAK-STAT signal pathwayQ39572277
p38 Mitogen-activated protein kinase up-regulates LPS-induced NF-kappaB activation in the development of lung injury and RAW 264.7 macrophagesQ40263878
The mechanisms of action of disease-modifying antirheumatic drugs: a review with emphasis on macrophage signal transduction and the induction of proinflammatory cytokinesQ41558341
Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injuryQ41837482
Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits type I-IV allergic inflammation and pro-inflammatory enzymesQ42979934
Shikonin attenuates lipopolysaccharide-induced acute lung injury in miceQ43415427
Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injuryQ44799601
Inhibition of the MAP kinase ERK protects from lipopolysaccharide-induced lung injury.Q45956507
Biliverdin administration protects against endotoxin-induced acute lung injury in ratsQ46697021
Effects of macrophage inducible nitric oxide synthase in murine septic lung injuryQ46895496
Effects of resolvin D1 on inflammatory responses and oxidative stress of lipopolysaccharide-induced acute lung injury in miceQ47907282
Adrenomedullin ameliorates lipopolysaccharide-induced acute lung injury in rats.Q50984021
Hyperbaric oxygen attenuation of lipopolysaccharide-induced acute lung injury involves heme oxygenase-1.Q53658254
Arctigenin attenuates lipopolysaccharide-induced acute lung injury in rats.Q54339177
Redox markers and inflammation are differentially affected by atorvastatin, pravastatin or simvastatin administered before endotoxin-induced acute lung injuryQ60713442
Isoforskolin pretreatment attenuates lipopolysaccharide-induced acute lung injury in animal modelsQ83312025
Ethyl pyruvate reduces acute lung injury via regulation of iNOS and HO-1 expression in endotoxemic ratsQ83418903
Long-term simvastatin attenuates lung injury and oxidative stress in murine acute lung injury models induced by oleic Acid and endotoxinQ83591299
Arctigenin protects focal cerebral ischemia-reperfusion rats through inhibiting neuroinflammationQ84966446
P433issue4
P921main subjectlipopolysaccharideQ421804
P304page(s)1406-1414
P577publication date2015-08-01
P1433published inInflammationQ2560341
P1476titleArctigenin Protects against Lipopolysaccharide-Induced Pulmonary Oxidative Stress and Inflammation in a Mouse Model via Suppression of MAPK, HO-1, and iNOS Signaling.
P478volume38

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cites work (P2860)
Q38759245Arctigenin Confers Neuroprotection Against Mechanical Trauma Injury in Human Neuroblastoma SH-SY5Y Cells by Regulating miRNA-16 and miRNA-199a Expression to Alleviate Inflammation
Q37026855Arctigenin Treatment Protects against Brain Damage through an Anti-Inflammatory and Anti-Apoptotic Mechanism after Needle Insertion
Q90495501Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes
Q40917622Arctigenin from Fructus Arctii (Seed of Burdock) Reinforces Intestinal Barrier Function in Caco-2 Cell Monolayers
Q52748426Arctigenin inhibits prostate tumor cell growth in vitro and in vivo.
Q88482875Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L
Q47096930Pseudane-VII Isolated from Pseudoalteromonas sp. M2 Ameliorates LPS-Induced Inflammatory Response In Vitro and In Vivo
Q58773456Quantitative Proteomic Analysis Reveals That Arctigenin Alleviates Concanavalin A-Induced Hepatitis Through Suppressing Immune System and Regulating Autophagy

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