| scholarly article | Q13442814 |
| P50 | author | Hartmut Kühn | Q104930966 |
| P2093 | author name string | Borngräber S | |
| Anton M | |||
| Gerth C | |||
| Fletterick R | |||
| Browner M | |||
| Gillmor S | |||
| P2860 | cites work | A primary determinant for lipoxygenase positional specificity | Q24311361 |
| The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity | Q27748747 | ||
| Mammalian lipoxygenases: molecular structures and functions | Q35460975 | ||
| A kinetic model for lipoxygenases based on experimental data with the lipoxygenase of reticulocytes | Q36432382 | ||
| Conversion of cucumber linoleate 13-lipoxygenase to a 9-lipoxygenating species by site-directed mutagenesis | Q36461982 | ||
| Relation between positional specificity and chirality in mammalian lipoxygenases. | Q37524019 | ||
| Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases | Q37888849 | ||
| Mammalian lipoxygenases: molecular and catalytic properties | Q38224172 | ||
| Rat 12-lipoxygenase: mutations of amino acids implicated in the positional specificity of 15- and 12-lipoxygenases | Q38319305 | ||
| Demonstration by EPR spectroscopy of the functional role of iron in soybean lipoxygenase-1 | Q39923298 | ||
| Cysteinyl leukotrienes in asthma: old mediators up to new tricks | Q40372475 | ||
| Regio- and stereochemistry of the dioxygenation reaction catalyzed by (S)-type lipoxygenases or by the cyclooxygenase activity of prostaglandin H synthases | Q40658010 | ||
| Lipoxygenase isoenzymes: a spectroscopic and structural characterization of soybean seed enzymes | Q41268483 | ||
| Attenuation of diet-induced atherosclerosis in rabbits with a highly selective 15-lipoxygenase inhibitor lacking significant antioxidant properties | Q41829508 | ||
| Defining the arachidonic acid binding site of human 15-lipoxygenase. Molecular modeling and mutagenesis | Q46138044 | ||
| Phenylalanine 353 is a primary determinant for the positional specificity of mammalian 15-lipoxygenases | Q48779626 | ||
| Conversion of human 15-lipoxygenase to an efficient 12-lipoxygenase: the side-chain geometry of amino acids 417 and 418 determine positional specificity. | Q52535821 | ||
| Soybean lipoxygenase-1 enzymically forms both (9S)- and (13S)-hydroperoxides from linoleic acid by a pH-dependent mechanism. | Q54147480 | ||
| Site-directed mutagenesis studies on the iron-binding domain and the determinant for the substrate oxygenation site of porcine leukocyte arachidonate 12-lipoxygenase. | Q54642665 | ||
| A function for lipoxygenase in programmed organelle degradation | Q59066725 | ||
| P433 | issue | 52 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 37345-37350 | |
| P577 | publication date | 1999-12-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Shape and specificity in mammalian 15-lipoxygenase active site. The functional interplay of sequence determinants for the reaction specificity. | |
| P478 | volume | 274 |
| Q34130491 | 15-lipoxygenase-1: a prooxidant enzyme |
| Q92877170 | A new lipoxygenase from the agaric fungus Agrocybe aegerita: Biochemical characterization and kinetic properties |
| Q37595527 | A single active site residue directs oxygenation stereospecificity in lipoxygenases: stereocontrol is linked to the position of oxygenation |
| Q43713839 | Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis |
| Q34761003 | An iron 13S-lipoxygenase with an α-linolenic acid specific hydroperoxidase activity from Fusarium oxysporum. |
| Q38650722 | Analysis of Large-Scale Mutagenesis Data To Assess the Impact of Single Amino Acid Substitutions. |
| Q41947559 | Applicability of the triad concept for the positional specificity of mammalian lipoxygenases |
| Q34159100 | Arachidonate 12-lipoxygenases |
| Q30481613 | Binding mode prediction of conformationally restricted anandamide analogs within the CB1 receptor |
| Q30366916 | Crystal structure of a lipoxygenase in complex with substrate: the arachidonic acid-binding site of 8R-lipoxygenase. |
| Q35204610 | Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) as a new strategy to provide safer non-steroidal anti-inflammatory drugs |
| Q42391524 | Dynamic behavior of fatty acid spin labels within a binding site of soybean lipoxygenase-1. |
| Q37142660 | Evolutionary alteration of ALOX15 specificity optimizes the biosynthesis of antiinflammatory and proresolving lipoxins |
| Q38272869 | Evolutionary aspects of lipoxygenases and genetic diversity of human leukotriene signaling. |
| Q87193616 | Four amino acid residues influence the substrate chain-length and regioselectivity of Siganus canaliculatus Δ4 and Δ5/6 desaturases |
| Q90603077 | Functional characterization of a novel arachidonic acid 12S-lipoxygenase in the halotolerant bacterium Myxococcus fulvus exhibiting complex social living patterns |
| Q47261787 | HPLC determination of antilipoxygenase activity of a water infusion of Ligustrum vulgare L. leaves and some of its constituents. |
| Q48294141 | Is Regioselectivity in the Enzyme-Catalyzed Hydroperoxidation of Arachidonic Acid Necessarily Determined by Hydrogen Abstraction? The Case of Rabbit Leu597Ala/Ile663Ala ALOX15 Mutant. |
| Q41049526 | Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase |
| Q41962866 | Lipoxygenase Activity Accelerates Programmed Spore Germination in Aspergillus fumigatus. |
| Q28709175 | Lipoxygenase pathways in Homo neanderthalensis: functional comparison with Homo sapiens isoforms |
| Q34997971 | Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications |
| Q28249730 | Mammalian lipoxygenases and their biological relevance |
| Q41978118 | Molecular basis for the reduced catalytic activity of the naturally occurring T560M mutant of human 12/15-lipoxygenase that has been implicated in coronary artery disease. |
| Q30479718 | Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration |
| Q30155827 | Molecular dynamics simulation of mammalian 15S-lipoxygenase with AMBER force field |
| Q31944643 | Mutagenesis and modelling of linoleate-binding to pea seed lipoxygenase |
| Q60860087 | On the Regio- and Stereospecificity of Arachidonic Acid Peroxidation Catalyzed by Mammalian 15-Lypoxygenases: A Combined Molecular Dynamics and QM/MM Study |
| Q38321170 | On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant |
| Q52932484 | Photoactivation of an inhibitor of the 12/15-lipoxygenase pathway. |
| Q26865357 | Rational approaches to improving selectivity in drug design |
| Q34727520 | Regulation of enzymatic lipid peroxidation: the interplay of peroxidizing and peroxide reducing enzymes |
| Q38796078 | Stereocontrol of arachidonic acid oxygenation by vertebrate lipoxygenases: newly cloned zebrafish lipoxygenase 1 does not follow the Ala-versus-Gly concept |
| Q21710694 | Structural and functional biology of arachidonic acid 15-lipoxygenase-1 (ALOX15) |
| Q31454807 | Structural basis for lipoxygenase specificity. Conversion of the human leukocyte 5-lipoxygenase to a 15-lipoxygenating enzyme species by site-directed mutagenesis. |
| Q34017581 | Structural basis for the positional specificity of lipoxygenases |
| Q27678989 | Structure of a Calcium-dependent 11R-Lipoxygenase Suggests a Mechanism for Ca2+ Regulation |
| Q36869340 | Structure, biochemistry and biology of hepoxilins: an update |
| Q60860104 | Substrate binding to mammalian 15-lipoxygenase |
| Q37015837 | Substrate specificity changes for human reticulocyte and epithelial 15-lipoxygenases reveal allosteric product regulation |
| Q44288313 | Suicidal inactivation of the rabbit 15-lipoxygenase by 15S-HpETE is paralleled by covalent modification of active site peptides |
| Q27646536 | The 1.85 Å Structure of an 8 R -Lipoxygenase Suggests a General Model for Lipoxygenase Product Specificity |
| Q30165432 | The N-terminal domain of the reticulocyte-type 15-lipoxygenase is not essential for enzymatic activity but contains determinants for membrane binding |
| Q30153264 | The structural basis for specificity in lipoxygenase catalysis |
| Q34952213 | Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology |
| Q24651921 | Tocotrienols in health and disease: the other half of the natural vitamin E family |
| Q36880038 | Tocotrienols: the emerging face of natural vitamin E |
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