Expression of cholera toxin B subunit-lumbrokinase in edible sunflower seeds-the use of transmucosal carrier to enhance its fusion protein's effect on protection of rats and mice against thrombosis

scientific article published on 7 August 2014

Expression of cholera toxin B subunit-lumbrokinase in edible sunflower seeds-the use of transmucosal carrier to enhance its fusion protein's effect on protection of rats and mice against thrombosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/BTPR.1963
P698PubMed publication ID25080206

P2093author name stringGang Wang
Xiaozhou Li
Jing Ji
Wenzhu Guan
Chao Jin
Chunfeng Guan
P2860cites workActivated human protein C prevents thrombin-induced thromboembolism in mice. Evidence that activated protein c reduces intravascular fibrin accumulation through the inhibition of additional thrombin generationQ39798451
A new era for plant biotechnology. A combination of pharmaceutical applications, technologies and safety measures could lead to new applications for genetically modified plantsQ41840107
Suppression of diabetes in non-obese diabetic (NOD) mice by oral administration of a cholera toxin B subunit-insulin B chain fusion protein vaccine produced in silkwormQ42035404
Agrobacterium tumefaciens mediated transient expression of plant cell wall-degrading enzymes in detached sunflower leavesQ42194564
The prostaglandin E2 receptor EP4 is expressed by human platelets and potently inhibits platelet aggregation and thrombus formationQ42821512
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Normal prothrombin time in the presence of therapeutic levels of rivaroxabanQ44834107
Expression of a Cholera Toxin B Subunit-Neutralizing Epitope of the Porcine Epidemic Diarrhea Virus Fusion Gene in Transgenic Lettuce (Lactuca sativa L.)Q45370503
Cloning and expression of earthworm fibrinolytic enzyme PM(246) in Pichia pastorisQ46606696
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The effect of dabigatran on the activated partial thromboplastin time and thrombin time as determined by the Hemoclot thrombin inhibitor assay in patient plasma samplesQ50893764
Experimental model of venous thrombosis in rats and effect of some agentsQ54737554
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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
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Crystal structure of earthworm fibrinolytic enzyme component a: revealing the structural determinants of its dual fibrinolytic activityQ27639417
Plant-made vaccines for humans and animals.Q30386732
Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coliQ33638891
The production of recombinant pharmaceutical proteins in plants.Q34267406
Cloning, Expression and Characterization of a Gene from Earthworm Eisenia fetida Encoding a Blood-Clot Dissolving ProteinQ34541679
Bioproduction of therapeutic proteins in the 21st century and the role of plants and plant cells as production platformsQ34624452
Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin, cholera toxin B subunit and CpG DNA.Q35192183
Considerations for the recovery of recombinant proteins from plantsQ35856734
A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetesQ36140954
Low-cost production of proinsulin in tobacco and lettuce chloroplasts for injectable or oral delivery of functional insulin and C-peptideQ36344923
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Plant seeds as bioreactors for recombinant protein productionQ37491535
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P433issue5
P921main subjectcholeraQ12090
thrombosisQ261327
edibilityQ123989417
P304page(s)1029-1039
P577publication date2014-08-07
P1433published inBiotechnology ProgressQ15753227
P1476titleExpression of cholera toxin B subunit-lumbrokinase in edible sunflower seeds-the use of transmucosal carrier to enhance its fusion protein's effect on protection of rats and mice against thrombosis
P478volume30

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cites work (P2860)
Q30235073A Perspective on the Development of Plant-Made Vaccines in the Fight against Ebola Virus
Q26738728Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
Q26775069Plants as Factories for Human Pharmaceuticals: Applications and Challenges
Q40840041Sunflower germin-like protein HaGLP1 promotes ROS accumulation and enhances protection against fungal pathogens in transgenic Arabidopsis thaliana.
Q41431573Transient Expression of Lumbrokinase (PI239) in Tobacco (Nicotiana tabacum) Using a Geminivirus-Based Single Replicon System Dissolves Fibrin and Blood Clots

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