Urotensin II promotes the production of LTC4 in rat aortic adventitial fibroblasts through NF-κB-5-LO pathway by p38 MAPK and ERK activations.

scientific article published on 30 September 2012

Urotensin II promotes the production of LTC4 in rat aortic adventitial fibroblasts through NF-κB-5-LO pathway by p38 MAPK and ERK activations. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00380-012-0291-0
P698PubMed publication ID23053343

P2093author name stringXiao Dong
Jing Zhao
Chaoshu Tang
Fen Peng
Xiaojin Ye
Nana Song
Beibing Di
Wenhui Ding
P2860cites workAtherosclerosis — An Inflammatory DiseaseQ26776972
Urotensin II is a new chemotactic factor for UT receptor-expressing monocytesQ28235675
Ligands and signaling of the G-protein-coupled receptor GPR14, expressed in human kidney cellsQ28307669
AGEs increased migration and inflammatory responses of adventitial fibroblasts via RAGE, MAPK and NF-kappaB pathwaysQ28574020
Aortic adventitial fibroblasts participate in angiotensin-induced vascular wall inflammation and remodelingQ34382219
Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysmQ34397052
Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertensionQ35175427
Urotensin II is an autocrine/paracrine growth factor for aortic adventitia of rat.Q38359653
HNE-induced 5-LO expression is regulated by NF-{kappa}B/ERK and Sp1/p38 MAPK pathways via EGF receptor in murine macrophagesQ39692043
Adrenomedullin induces matrix metalloproteinase-2 activity in rat aortic adventitial fibroblastsQ42470041
5-Lipoxygenase is involved in the angiotensin II-induced NAD(P)H-oxidase activationQ44546829
The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm.Q45025551
Proliferation and anti-apoptotic effects of human urotensin II on human endothelial cellsQ46847093
Gax gene transfer inhibits vascular remodeling induced by adventitial inflammation in rabbits.Q50548176
NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.Q50922730
Effects of exogenous urotensin II on vascular remodelling after balloon injury.Q53358853
The pro-angiogenic activity of urotensin-II on human vascular endothelial cells involves ERK1/2 and PI3K signaling pathways.Q54691256
Comparison between adventitial and intimal inflammation of ruptured and nonruptured atherosclerotic plaques in human coronary arteriesQ74579511
Leukotriene B4 receptor antagonism reduces monocytic foam cells in miceQ77743269
Adventitial fibroblasts are activated in the early stages of atherosclerosis in the apolipoprotein E knockout mouseQ79399611
The lamina adventitia is the major site of immune cell accumulation in standard chow-fed apolipoprotein E-deficient miceQ81250761
Alteration of vascular urotensin II receptor in mice with apolipoprotein E gene knockoutQ81569104
Adventitial lymphatics of internal carotid artery in healthy and atherosclerotic vesselsQ83181621
Adventitial lymphocytic inflammation in human coronary arteries with intimal atherosclerosisQ83679745
Intravascular ultrasound assessment of the association between spatial orientation of ruptured coronary plaques and remodeling morphology of culprit plaques in ST-elevation acute myocardial infarctionQ84890804
Association of serum levels of arachidonic acid and eicosapentaenoic acid with prevalence of major adverse cardiac events after acute myocardial infarctionQ85233181
P433issue4
P921main subjectNF-κBQ411114
P304page(s)514-523
P577publication date2012-09-30
P1433published inHeart and VesselsQ15766690
P1476titleUrotensin II promotes the production of LTC4 in rat aortic adventitial fibroblasts through NF-κB-5-LO pathway by p38 MAPK and ERK activations.
P478volume28

Reverse relations

cites work (P2860)
Q36492706A closer look at the role of urotensin II in the metabolic syndrome
Q34765931Inhibition of UII/UTR system relieves acute inflammation of liver through preventing activation of NF-κB pathway in ALF mice
Q36289344MCPIP1 Regulates Fibroblast Migration in 3-D Collagen Matrices Downstream of MAP Kinases and NF-κB
Q35108921Urotensin II induces interleukin 8 expression in human umbilical vein endothelial cells
Q47275813Urotensin II promotes aldosterone expression in rat aortic adventitial fibroblasts
Q92277029Urotensin II promotes secretion of LTB4 through 5-lipoxygenase via the UT-ROS-Akt pathway in RAW264.7 macrophages

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