Ligand-dependent tau filament formation: implications for Alzheimer's disease progression.

scientific article published in November 1999

Ligand-dependent tau filament formation: implications for Alzheimer's disease progression. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/BI9911839
P8608Fatcat IDrelease_3jpi236nxvdq5kzhuql67pbwgq
P698PubMed publication ID10555967
P5875ResearchGate publication ID12744904

P50authorLester I BinderQ125310929
P2093author name stringKing ME
Ahuja V
Kuret J
P433issue45
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
P304page(s)14851-14859
P577publication date1999-11-01
P1433published inBiochemistryQ764876
P1476titleLigand-dependent tau filament formation: implications for Alzheimer's disease progression.
P478volume38

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cites work (P2860)
Q47715943Amyloidogenesis of Tau protein
Q42714396Analysis of isoform-specific tau aggregates suggests a common toxic mechanism involving similar pathological conformations and axonal transport inhibition
Q44429258Anionic Micelles and Vesicles Induce Tau Fibrillization in Vitro
Q36964038Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure
Q41240079Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein.
Q46858641C-terminal truncation modulates both nucleation and extension phases of tau fibrillization
Q35136746Calpain-mediated tau cleavage: a mechanism leading to neurodegeneration shared by multiple tauopathies
Q38287992Cell-based Models To Investigate Tau Aggregation
Q38350075Cellular factors modulating the mechanism of tau protein aggregation
Q45328065Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease
Q44555436Comparative distribution of tau phosphorylated at Ser262 in pre-tangles and tangles
Q42082255Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein
Q40199573Cytosine beta-D-arabinofuranoside used as a paradigm modifier to increase production of tau aggregates in a cellular model of tauopathy
Q30435267Cytoskeletal pathologies of Alzheimer disease
Q51263482Detection and Quantification Methods for Fibrillar Products of In Vitro Tau Aggregation Assays.
Q36609379Detection and quantification of tau aggregation using a membrane filter assay
Q47824973Development of tau PET Imaging Ligands and their Utility in Preclinical and Clinical Studies.
Q91583395Different Amyloid-β Self-Assemblies Have Distinct Effects on Intracellular Tau Aggregation
Q40891013Differential assembly of human tau isoforms in the presence of arachidonic acid
Q33296123Differentiating Alzheimer disease-associated aggregates with small molecules
Q38733357EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimer's disease.
Q42836387FTDP-17 tau mutations induce distinct effects on aggregation and microtubule interactions
Q41820128Formation and propagation of tau oligomeric seeds
Q36224314Fourier Transform Infrared (FTIR) Spectroscopy, Ultraviolet Resonance Raman (UVRR) Spectroscopy, and Atomic Force Microscopy (AFM) for Study of the Kinetics of Formation and Structural Characterization of Tau Fibrils
Q43662734Functional differences of tau isoforms containing 3 or 4 C-terminal repeat regions and the influence of oxidative stress
Q42061829GSK-3beta phosphorylation of functionally distinct tau isoforms has differential, but mild effects
Q28597211Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies
Q53317312Inhibition of phospholipase A2 in rat brain decreases the levels of total Tau protein.
Q36874806Initiation of assembly of tau(273-284) and its ΔK280 mutant: an experimental and computational study.
Q39035486Interactions between Microtubule-Associated Protein Tau (MAPT) and Small Molecules
Q36368413Ligand electronic properties modulate tau filament binding site density
Q34074190Neuroinflammatory signaling upregulation in Alzheimer's disease
Q53236118Nonsaturable binding indicates clustering of tau on the microtubule surface in a paired helical filament-like conformation.
Q30481896Nucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constants
Q36082071Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases
Q34579395Peroxynitrite-induced nitrative and oxidative modifications alter tau filament formation.
Q30504709Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.
Q33287254Potency of a tau fibrillization inhibitor is influenced by its aggregation state
Q41940387Pre-assembled tau filaments phosphorylated by GSK-3b form large tangle-like structures
Q31111749Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro
Q41484754Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport
Q42422246RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth
Q47609800Rapid Anionic Micelle-mediated α-Synuclein Fibrillization in Vitro
Q27315041Simulated cytoskeletal collapse via tau degradation
Q45284384Site-specific pseudophosphorylation modulates the rate of tau filament dissociation
Q35840438Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
Q35841983Structural analysis of Pick's disease-derived and in vitro-assembled tau filaments
Q44116139Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis
Q40421137Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro
Q46445872Tau Oligomers as Pathogenic Seeds: Preparation and Propagation In Vitro and In Vivo
Q37238281Tau aggregation and toxicity in tauopathic neurodegenerative diseases
Q42429043Tau phosphorylation by GSK-3beta promotes tangle-like filament morphology
Q48858275Tau-66: evidence for a novel tau conformation in Alzheimer's disease
Q36671491Template-assisted filament growth by parallel stacking of tau.
Q47137171The Molecular Chaperone Artemin Efficiently Blocks Fibrillization of TAU Protein In Vitro
Q30490027The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.
Q33880243The role of the lipid bilayer in tau aggregation
Q53532759The tau N279K exon 10 splicing mutation recapitulates frontotemporal dementia and parkinsonism linked to chromosome 17 tauopathy in a mouse model.
Q35604223Understanding the kinetic roles of the inducer heparin and of rod-like protofibrils during amyloid fibril formation by Tau protein
Q35836408tau kinases in the rat heat shock model: possible implications for Alzheimer disease