Use of CSF biomarkers in Alzheimer's disease clinical trials.

scientific article published in April 2009

Use of CSF biomarkers in Alzheimer's disease clinical trials. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12603-009-0043-8
P698PubMed publication ID19300880

P50authorHenrik ZetterbergQ6252048
Kaj BlennowQ28321550
P2860cites workAlzheimer's diseaseQ29616743
Core candidate neurochemical and imaging biomarkers of Alzheimer's diseaseQ31162752
Differential increase in cerebrospinal fluid-acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's diseaseQ32065439
Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid studyQ34287865
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.Q34417339
CSF markers for incipient Alzheimer's diseaseQ35541472
Cerebrospinal fluid beta-amyloid 1-42 concentration may predict cognitive decline in older womenQ36227420
CSF biomarkers for Alzheimer's disease: use in early diagnosis and evaluation of drug treatmentQ36252166
Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trialQ40064054
Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up studyQ40349700
Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231.Q44091581
Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors.Q44291669
Reductions in beta-amyloid concentrations in vivo by the gamma-secretase inhibitors BMS-289948 and BMS-299897.Q45238128
First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primatesQ46317257
CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy studyQ48381623
Cerebrospinal fluid beta-amyloid 42 is reduced before the onset of sporadic dementia: a population-based study in 85-year-oldsQ48388907
CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's diseaseQ48408159
Safety and acceptability of the research lumbar puncture.Q50951405
Cerebrospinal fluid biomarkers predict decline in subjective cognitive function over 3 years in healthy elderly.Q51901649
Intra-individual stability of CSF biomarkers for Alzheimer's disease over two years.Q51969054
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.Q51986028
Longitudinal stability of CSF biomarkers in Alzheimer's disease.Q53286684
Low frequency of post-lumbar puncture headache in demented patientsQ72646181
Evaluation of CSF-tau and CSF-Abeta42 as diagnostic markers for Alzheimer disease in clinical practiceQ73632001
P433issue4
P921main subjectAlzheimer's diseaseQ11081
biomarkerQ864574
P304page(s)358-361
P577publication date2009-04-01
P1433published inThe Journal of Nutrition, Health and AgingQ23051112
P1476titleUse of CSF biomarkers in Alzheimer's disease clinical trials.
P478volume13

Reverse relations

cites work (P2860)
Q50972636A quantum dot probe conjugated with aβ antibody for molecular imaging of Alzheimer's disease in a mouse model.
Q34679106Cerebrospinal fluid profiles and prospective course and outcome in patients with amnestic mild cognitive impairment
Q53321175Editorial: can we improve care for patients with dementia?
Q28072061Harnessing Cerebrospinal Fluid Biomarkers in Clinical Trials for Treating Alzheimer's and Parkinson's Diseases: Potential and Challenges
Q53300553Imaging and biomarkers will be used for detection and monitoring progression of early Alzheimer's disease.
Q34228544Quantifying factors for the success of stratified medicine
Q38149355Risk factors for the progression of mild cognitive impairment to dementia
Q53300550Use of biomarkers in Alzheimer's trials.
Q37980501Use of cerebrospinal fluid biomarkers in clinical trials for schizophrenia and depression

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