Increased COX-2 expression in epithelial and stromal cells of high mammographic density tissues and in a xenograft model of mammographic density.

scientific article published on 31 July 2015

Increased COX-2 expression in epithelial and stromal cells of high mammographic density tissues and in a xenograft model of mammographic density. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10549-015-3520-2
P2888exact matchhttps://scigraph.springernature.com/pub.10.1007/s10549-015-3520-2
P698PubMed publication ID26227474
P5875ResearchGate publication ID280583241

P50authorKara L. BrittQ37370390
Erik W. ThompsonQ37829135
John HopperQ56726496
P2093author name stringD Huang
G L Chew
M A Henderson
P Hill
J Cawson
I Haviv
C W Huo
H Frazer
P2860cites workDynamic changes in high and low mammographic density human breast tissues maintained in murine tissue engineering chambers during various murine peripartum states and over timeQ57305981
Image-guided sampling reveals increased stroma and lower glandular complexity in mammographically dense breast tissueQ57305995
Tamoxifen-Induced Reduction in Mammographic Density and Breast Cancer Risk Reduction: A Nested Case-Control StudyQ59288218
Aspirin intake and survival after breast cancerQ24604280
Cyclooxygenase-2 (COX-2), aromatase and breast cancer: a possible role for COX-2 inhibitors in breast cancer chemopreventionQ28193249
NSAIDs and breast cancer recurrence in a prospective cohort studyQ28221965
Nonsteroidal anti-inflammatory drugs and change in mammographic density: a cohort study using pharmacy records on over 29,000 postmenopausal womenQ33811534
Collagen density promotes mammary tumor initiation and progressionQ33845553
COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatmentQ33877411
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2.Q34206453
Mammographic density and breast cancer risk: current understanding and future prospectsQ34235753
Cyclo-oxygenase 2 expression is associated with angiogenesis and lymph node metastasis in human breast cancer.Q35586182
Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progressionQ35735316
High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epitheliumQ35797147
Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysisQ36507079
Prediction of breast cancer risk based on profiling with common genetic variantsQ36583004
Breast cancer and NSAID use: a meta-analysisQ36622959
Correlation of COX-2 and Ep-CAM overexpression in human invasive breast cancer and its impact on survivalQ36649103
A randomised controlled phase II trial of pre-operative celecoxib treatment reveals anti-tumour transcriptional response in primary breast cancerQ36903254
Mammographic density reduction is a prognostic marker of response to adjuvant tamoxifen therapy in postmenopausal patients with breast cancerQ36916765
Tissue composition of mammographically dense and non-dense breast tissueQ36999585
No effect of aspirin on mammographic density in a randomized controlled clinical trialQ37210539
Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast densityQ37400742
Preventive therapy for breast cancer: a consensus statementQ37858249
Mammographic density-a review on the current understanding of its association with breast cancerQ38194952
Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3.Q38291062
COX-2 promotes breast cancer cell radioresistance via p38/MAPK-mediated cellular anti-apoptosis and invasivenessQ39138862
High and low mammographic density human breast tissues maintain histological differential in murine tissue engineering chambersQ39597471
The association of measured breast tissue characteristics with mammographic density and other risk factors for breast cancer.Q44406183
Cyclooxygenase-2 expression in proliferative Ki-67-positive breast cancers is associated with poor outcomes.Q53389613
COX-2 is expressed in human pulmonary, colonic, and mammary tumors.Q53402915
Effects of Tamoxifen and oestrogen on histology and radiographic density in high and low mammographic density human breast tissues maintained in murine tissue engineering chambers.Q53408150
Reversal of tamoxifen resistance of human breast carcinomas in vivo by neutralizing antibodies to transforming growth factor-beta.Q54108530
Associations of mammographic dense and nondense areas and body mass index with risk of breast cancer.Q54679615
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectxenograftQ64148587
P304page(s)89-99
P577publication date2015-07-31
P1433published inBreast Cancer Research and TreatmentQ326085
P1476titleIncreased COX-2 expression in epithelial and stromal cells of high mammographic density tissues and in a xenograft model of mammographic density.
P478volume153

Reverse relations

cites work (P2860)
Q92282046Adjuvant Therapy and Mammographic Density Changes in Women With Breast Cancer
Q55117383An overview of mammographic density and its association with breast cancer.
Q37579197CCL2-driven inflammation increases mammary gland stromal density and cancer susceptibility in a transgenic mouse model.
Q58793402High mammographic density in women is associated with protumor inflammation
Q59799817Mammographic density and breast tissue expression of inflammatory markers, growth factors, and vimentin
Q28074177Mammographic density: a potential monitoring biomarker for adjuvant and preventative breast cancer endocrine therapies
Q50214824Pre-clinical effects of metformin and aspirin on the cell lines of different breast cancer subtypes.
Q28066162Stromal characteristics may hold the key to mammographic density: the evidence to date

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