scholarly article | Q13442814 |
P50 | author | Ian Wilson | Q38644500 |
Alex J Gavin | Q58132289 | ||
P2093 | author name string | Elin Karlsson | |
Huw B Jones | |||
Sunil Sarda | |||
Kathryn Pickup | |||
Timothy Schulz-Utermoehl | |||
Chris Page | |||
Kerry Ratcliffe | |||
P2860 | cites work | Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas | Q28343187 |
Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism | Q28510829 | ||
Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2 | Q28591646 | ||
Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways | Q28679171 | ||
Xenobiotic acyl glucuronides and acyl CoA thioesters as protein-reactive metabolites with the potential to cause idiosyncratic drug reactions | Q34717194 | ||
Acyl glucuronide reactivity in perspective: biological consequences | Q35103665 | ||
Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity | Q35566803 | ||
Acyl glucuronides: the good, the bad and the ugly. | Q37787116 | ||
NSAID acyl glucuronides and enteropathy | Q37852045 | ||
Biotransformation of diclofenac sodium (Voltaren) in animals and in man. I. Isolation and identification of principal metabolites | Q39710218 | ||
Diclofenac covalent protein binding is dependent on acyl glucuronide formation and is inversely related to P450-mediated acute cell injury in cultured rat hepatocytes | Q42558143 | ||
Integrated HPLC-MS and (1)H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides. | Q43240503 | ||
Diclofenac metabolism in the mouse: novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry. | Q53404409 | ||
Conditional Gene Knockout Using Cre Recombinase | Q56114286 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Diclofenac | Q244408 |
P304 | page(s) | 195-205 | |
P577 | publication date | 2011-09-28 | |
P1433 | published in | Xenobiotica | Q1360678 |
P1476 | title | The hepatic reductase null mouse as a model for exploring hepatic conjugation of xenobiotics: application to the metabolism of diclofenac | |
P478 | volume | 42 |
Q41010784 | Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice |
Q51301442 | Application of Osmotic Pumps for Sustained Release of 1-Aminobenzotriazole and Inhibition of Cytochrome P450 Enzymes in Mice: Model Comparison with the Hepatic P450 Reductase Null Mouse. |
Q42702145 | Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice |
Q48813784 | The metabolic fate of [14C]-fenclozic acid in the hepatic reductase null (HRN) mouse |
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