Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy.

scientific article published in July 1999

Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0940-2993(99)80033-5
P698PubMed publication ID10445409

P2093author name stringA Breuer
E Frei
C A Bieler
H H Schmeiser
M Stiborová
P2860cites workRapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbsQ28248709
Mechanism of formation and structural characterization of DNA adducts derived from peroxidative activation of benzidineQ42209031
32P-adduct assay: comparative recoveries of structurally diverse DNA adducts in the various enhancement proceduresQ42214916
Studies on the metabolism of aristolochic acids I and II.Q42220010
The first identification of the benzenediazonium ion formation from a non-aminoazo dye, 1-phenylazo-2-hydroxynaphthalene (Sudan I) by microsomes of rat liversQ43825488
Mechanism of formation and 32P-postlabeling of DNA adducts derived from peroxidative activation of carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I).Q46494713
Identification and mutagenicity of metabolites of aristolochic acid formed by rat liver.Q50204413
Mutagenicity of the two main components of commercially available carcinogenic aristolochic acid in Salmonella typhimurium.Q50208536
Nuclease P1-mediated enhancement of sensitivity of 32P-postlabeling test for structurally diverse DNA adducts.Q54423710
Comparison of DNA adduct formation by aristolochic acids in various in vitro activation systems by 32P-post-labelling: evidence for reductive activation by peroxidasesQ63253399
32P-post-labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathyQ63253400
Cytochrome P-450 and Peroxidase Oxidize Detoxication Products of Carcinogenic Aristolochic Acids (Aristolactams) to Reactive Metabolites Binding to DNA in vitroQ63253411
Characterization of DNA adducts formed by aristolochic acids in the target organ (forestomach) of rats by 32P-postlabelling analysis using different chromatographic proceduresQ63253413
Tumour induction in mice following exposure to aristolochic acidQ67967425
Comparison of 32P-postlabeling and high pressure liquid chromatographic analyses for 7,12-dimethylbenz[a]anthracene--DNA adductsQ70383798
The isolation and structural elucidation of novel derivatives of aristolochic acid from Aristolochia indicaQ72280170
Seven aristololactams from Aristolochia argentinaQ104394049
P433issue4-5
P304page(s)421-427
P577publication date1999-07-01
P1433published inExperimental and Toxicologic PathologyQ15724492
P1476titleAristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy.
P478volume51

Reverse relations

cites work (P2860)
Q3342284413C-NMR data of diterpenes isolated from Aristolochia Species
Q90565908Acrolein contributes to urothelial carcinomas in patients with chronic kidney disease
Q36667086Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1.
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Q35606719Herbal bioactivation: the good, the bad and the ugly
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