review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Di Cui | |
Xiangru Xu | |||
P2860 | cites work | DNA methylation age of human tissues and cell types | Q21183994 |
Cloning, expression and chromosome locations of the human DNMT3 gene family | Q22010469 | ||
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development | Q22010765 | ||
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex | Q24324026 | ||
A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters | Q24537436 | ||
Loss of recent memory after bilateral hippocampal lesions | Q24564342 | ||
DNA methylation and memory formation | Q24596970 | ||
Memory and the NMDA receptors | Q24603015 | ||
Global prevalence of dementia: a Delphi consensus study | Q24603249 | ||
HDAC2 negatively regulates memory formation and synaptic plasticity. | Q24611806 | ||
Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2 | Q24615012 | ||
Adult neurogenesis in the mammalian brain: significant answers and significant questions | Q24628935 | ||
Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss | Q24630545 | ||
The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome | Q24647294 | ||
DNA N(6)-methyladenine: a new epigenetic mark in eukaryotes? | Q26778358 | ||
DNA methylation and healthy human aging | Q27012262 | ||
Orphan CpG islands identify numerous conserved promoters in the mammalian genome | Q28109656 | ||
The hallmarks of aging | Q28131641 | ||
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality | Q28131773 | ||
DNA methyltransferase Dnmt1 associates with histone deacetylase activity | Q28141500 | ||
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex | Q28143627 | ||
Polymorphic variation in the epigenetic gene DNMT3B modulates the environmental impact on cognitive ability: a twin study | Q50454768 | ||
DNMT3A moderates cognitive decline in subjects with mild cognitive impairment: replicated evidence from two mild cognitive impairment cohorts | Q50581281 | ||
Methylation levels of maternal and paternal genomes during preimplantation development | Q50798002 | ||
Reduction in DNA methyltransferases and alteration of DNA methylation pattern associate with mouse skin ageing. | Q51519751 | ||
From stem cells to grandmother cells: how neurogenesis relates to learning and memory. | Q51949411 | ||
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. | Q51956004 | ||
Large-scale human promoter mapping using CpG islands. | Q52105620 | ||
DNA methylation changes at TREM2 intron 1 and TREM2 mRNA expression in patients with Alzheimer's disease. | Q53503415 | ||
Hutchinson-Gilford progeria syndrome: review of the phenotype. | Q55042199 | ||
Stimulation effect of Dnmt3L on the DNA methylation activity of Dnmt3a2 | Q80198565 | ||
Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome | Q82660672 | ||
Cortical DNA methylation maintains remote memory | Q42285452 | ||
DNMT1 mutations found in HSANIE patients affect interaction with UHRF1 and neuronal differentiation | Q42291322 | ||
Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation. | Q42523444 | ||
UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9. | Q42824871 | ||
Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation | Q45862749 | ||
Reduction in size of perforated postsynaptic densities in hippocampal axospinous synapses and age-related spatial learning impairments. | Q47408579 | ||
Dnmt3a2: a hub for enhancing cognitive functions | Q47616756 | ||
Early-Life Gene Expression in Neurons Modulates Lasting Epigenetic States | Q47620033 | ||
Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases. | Q47647776 | ||
Active and passive demethylation of male and female pronuclear DNA in the mammalian zygote | Q47981749 | ||
Epigenetic regulation of Dnmt3a and Arc gene expression after electroconvulsive stimulation in the rat. | Q48078778 | ||
Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice | Q48149199 | ||
Activation of the prefrontal cortex in a nonspatial working memory task with functional MRI. | Q48192075 | ||
Spatial working memory in humans as revealed by PET. | Q48266348 | ||
The effects of hippocampal lesions upon spatial and non-spatial tests of working memory | Q48378274 | ||
The epigenotype. 1942. | Q48429495 | ||
Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. | Q48587952 | ||
The 5-methylcytosine in DNA of rats. Tissue and age specificity and the changes induced by hydrocortisone and other agents | Q48693317 | ||
DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. | Q49078217 | ||
DNA mismatch repair and DNA methylation in adult brain neurons. | Q49158568 | ||
Hippocampus-dependent memory and allele-specific gene expression in adult offspring of alcohol-consuming dams after neonatal treatment with thyroxin or metformin. | Q49163873 | ||
No association of the variant rs11887120 in DNMT3A with cognitive decline in individuals with mild cognitive impairment | Q50217511 | ||
Replication timing-related and gene body-specific methylation of active human genes. | Q39626565 | ||
The Janus face of DNA methylation in aging | Q39914567 | ||
DNA methylation changes in plasticity genes accompany the formation and maintenance of memory. | Q40222482 | ||
Loss of axosomatic synapses in the dentate gyrus of aged rats | Q41547831 | ||
Brain-Derived Neurotrophic Factor/TrkB Signaling in Memory Processes | Q28201636 | ||
Memory formation: the sequence of biochemical events in the hippocampus and its connection to activity in other brain structures | Q28256467 | ||
DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction | Q28258202 | ||
The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory | Q28300376 | ||
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases | Q28507226 | ||
Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1 | Q28575665 | ||
Covalent modification of DNA regulates memory formation | Q28576256 | ||
Functions of DNA methylation: islands, start sites, gene bodies and beyond | Q29547260 | ||
Perceptions of epigenetics | Q29547310 | ||
DNA methylation: roles in mammalian development | Q29616796 | ||
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome | Q29616819 | ||
DNA methylation landscapes: provocative insights from epigenomics | Q29617144 | ||
Cancer epigenetics comes of age | Q29617275 | ||
The DNA methyltransferases of mammals | Q29617317 | ||
Global epigenomic reconfiguration during mammalian brain development | Q29617800 | ||
Chromatin modification and epigenetic reprogramming in mammalian development | Q29617802 | ||
Epigenetic modifications and human disease | Q29619753 | ||
DNA methylation regulates associative reward learning | Q30547330 | ||
DNA methylation on N(6)-adenine in mammalian embryonic stem cells | Q30796539 | ||
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons | Q33299459 | ||
Multi-tissue DNA methylation age predictor in mouse | Q33556578 | ||
Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts | Q33557670 | ||
DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes | Q33742114 | ||
Epigenetic aging clocks in mice and men | Q33795803 | ||
Epigenetic modifications: basic mechanisms and role in cardiovascular disease (2013 Grover Conference series). | Q33806018 | ||
Mammalian methyltransferases and methyl-CpG-binding domains: proteins involved in DNA methylation | Q33913612 | ||
Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation. | Q33945996 | ||
Cytosine methylation and CpG, TpG (CpA) and TpA frequencies | Q33978876 | ||
Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities | Q34032603 | ||
DNA Methylation on N6-Adenine in C. elegans | Q34043905 | ||
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. | Q34103901 | ||
Genomic 5-methyldeoxycytidine decreases with age. | Q34185566 | ||
Epigenetic changes in Alzheimer's disease: decrements in DNA methylation | Q34233161 | ||
Working memory: looking back and looking forward | Q34267089 | ||
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci | Q34433829 | ||
Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. | Q34579673 | ||
Selective role for DNMT3a in learning and memory | Q34602652 | ||
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia | Q34627568 | ||
The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells | Q34670376 | ||
Epigenetic gene regulation in the adult mammalian brain: multiple roles in memory formation | Q35036368 | ||
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. | Q35169651 | ||
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells | Q35554558 | ||
DNA methylation signatures in development and aging of the human prefrontal cortex | Q35748368 | ||
Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation | Q35941031 | ||
DNA methylation and cognitive aging | Q35987240 | ||
Dynamics of DNA methylation in aging and Alzheimer's disease | Q36290480 | ||
DNA Methylation and Tag SNPs of the BDNF Gene in Conversion of Amnestic Mild Cognitive Impairment into Alzheimer's Disease: A Cross-Sectional Cohort Study | Q36339504 | ||
Adult neurogenesis and functional plasticity in neuronal circuits | Q36404122 | ||
DNMT1 mutation hot spot causes varied phenotypes of HSAN1 with dementia and hearing loss. | Q36687168 | ||
Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer | Q36848353 | ||
DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe. | Q36873208 | ||
DNA methylation impacts on learning and memory in aging | Q36938828 | ||
Epigenetic regulation in mammalian preimplantation embryo development | Q37242454 | ||
Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients. | Q37638856 | ||
S-adenosylmethionine levels regulate the schwann cell DNA methylome. | Q37651384 | ||
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos. | Q37729754 | ||
Alzheimer's disease genetics: current knowledge and future challenges | Q37801363 | ||
Region-specific genetic alterations in the aging hippocampus: implications for cognitive aging | Q37806962 | ||
DNA methylation and its basic function | Q38025275 | ||
Cellular changes in the enteric nervous system during ageing | Q38093934 | ||
Emerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns | Q38256826 | ||
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. | Q38296215 | ||
Neuronal activity modifies the DNA methylation landscape in the adult brain | Q38594616 | ||
TREM2 variants: new keys to decipher Alzheimer disease pathogenesis | Q38748724 | ||
Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions. | Q38852379 | ||
Dnmt1, Dnmt3a and Dnmt3b cooperate in photoreceptor and outer plexiform layer development in the mammalian retina. | Q39171810 | ||
Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration | Q39230518 | ||
Elucidating the Role of TREM2 in Alzheimer's Disease | Q39252469 | ||
Neuronal DNA Methyltransferases: Epigenetic Mediators between Synaptic Activity and Gene Expression? | Q39312657 | ||
Amyloid protein-mediated differential DNA methylation status regulates gene expression in Alzheimer's disease model cell line | Q39457542 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | brain | Q1073 |
DNA methylation | Q874745 | ||
enzyme | Q8047 | ||
nervous system | Q9404 | ||
cognitive dysfunction | Q57859955 | ||
P577 | publication date | 2018-04-28 | |
P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
P1476 | title | DNA Methyltransferases, DNA Methylation, and Age-Associated Cognitive Function. | |
P478 | volume | 19 |
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