Effects of factor Xa and protein S on the individual activated protein C-mediated cleavages of coagulation factor Va.

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Effects of factor Xa and protein S on the individual activated protein C-mediated cleavages of coagulation factor Va. is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M606441200
P698PubMed publication ID16935856

P2093author name stringBjörn Dahlbäck
Mårten Steen
Sinh Tran
Eva A Norstrøm
P2860cites workFamilial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein CQ24563608
Complete cDNA and derived amino acid sequence of human factor VQ24605169
Cloning of a cDNA coding for human factor V, a blood coagulation factor homologous to factor VIII and ceruloplasminQ24629849
Proposed structural models of the prothrombinase (FXa-FVa) complexQ28293819
Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein CQ28631087
Factor V and thrombotic disease: description of a janus-faced proteinQ34123469
Peptide Bond Cleavages and Loss of Functional Activity during Inactivation of Factor Va and Factor VaR506Q by Activated Protein CQ34305158
Mutation in blood coagulation factor V associated with resistance to activated protein C.Q34340007
Binding sites for blood coagulation factor Xa and protein S involving residues 493-506 in factor Va.Q36280112
Human coagluation factor V purification and thrombin-catalyzed activationQ37028310
Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein CQ38269759
Removal of B-domain sequences from factor V rather than specific proteolysis underlies the mechanism by which cofactor function is realizedQ40581702
Enhancing the activity of protein C by mutagenesis to improve the membrane-binding site: studies related to proline-10.Q41070092
Purification of human vitamin K-dependent protein S and its limited proteolysis by thrombinQ42167364
Defining the factor Xa-binding site on factor Va by site-directed glycosylationQ44183079
Importance of protein S and phospholipid for activated protein C-mediated cleavages in factor Va.Q44411439
Binding site for blood coagulation factor Xa involving residues 311-325 in factor Va.Q44798012
Enhanced rate of cleavage at Arg-306 and Arg-506 in coagulation factor Va by Gla domain-mutated human-activated protein C.Q45037100
Factor V Arg306-->Thr (factor V Cambridge) and factor V Arg306-->Gly mutations in venous thrombotic disease.Q50852038
Functional characterization of recombinant FV Hong Kong and FV Cambridge.Q53966443
P433issue42
P407language of work or nameEnglishQ1860
P304page(s)31486-31494
P577publication date2006-08-25
P1433published inJournal of Biological ChemistryQ867727
P1476titleEffects of factor Xa and protein S on the individual activated protein C-mediated cleavages of coagulation factor Va.
P478volume281