Pathophysiology of RANK ligand (RANKL) and osteoprotegerin (OPG).

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Pathophysiology of RANK ligand (RANKL) and osteoprotegerin (OPG). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0003-4266(06)72569-0
P698PubMed publication ID16639364

P2093author name stringL C Hofbauer
P2860cites workOsteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the boneQ39946634
The effect of a single dose of osteoprotegerin in postmenopausal womenQ43520860
A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastasesQ44291815
A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal womenQ46133598
Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cordQ73766127
Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environmentQ77337113
Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myelomaQ77337118
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
RANK is essential for osteoclast and lymph node developmentQ24598872
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligandQ24653311
Bone resorption by osteoclastsQ28145169
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandQ29619331
Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progressionQ33944735
Role of RANK ligand in mediating increased bone resorption in early postmenopausal womenQ34912769
RANK ligand and osteoprotegerin in myeloma bone disease.Q34992857
Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infectionQ35008871
Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases.Q35848843
Circulating osteoprotegerin and receptor activator for nuclear factor kappaB ligand: clinical utility in metabolic bone disease assessmentQ36232629
Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesisQ36368706
P433issue2
P921main subjectpathophysiologyQ1135939
P304page(s)139-141
P577publication date2006-04-01
P1433published inAnnales d'EndocrinologieQ15753551
P1476titlePathophysiology of RANK ligand (RANKL) and osteoprotegerin (OPG)
P478volume67

Reverse relations

cites work (P2860)
Q36171870Baseline serum RANKL levels may serve to predict remission in rheumatoid arthritis patients treated with TNF antagonists
Q40719297Increased calcification in osteoprotegerin-deficient smooth muscle cells: Dependence on receptor activator of NF-κB ligand and interleukin 6.
Q35886675No evidence of circulating autoantibodies against osteoprotegerin in patients with celiac disease
Q37059853Osteoporosis in celiac disease and in endocrine and reproductive disorders
Q37344527Role of RANKL-RANK/osteoprotegerin pathway in cardiovascular and bone disease associated with HIV infection
Q80463776[Bone metabolism: molecular mechanisms]
Q87840407[Inflammation and bone metabolism]
Q80149611[New pathophysological relevant metabolic pathways in osteoporosis. Future innovative therapies?]
Q90155672[Rheumatism and bone metabolism]

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