Aberrant expression of CD123 (interleukin-3 receptor-α) on neoplastic mast cells.

scientific article

Aberrant expression of CD123 (interleukin-3 receptor-α) on neoplastic mast cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/LEU.2015.16
P698PubMed publication ID25640886
P5875ResearchGate publication ID273637276

P50authorAyalew TefferiQ66370740
P2093author name stringD Chen
A Pardanani
C A Hanson
C Finke
C Brooks
M M Patnaik
K K Reichard
E Rowinsky
T K Kimlinger
T Lasho
D Zblewski
P2860cites workThe interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cellsQ28140494
Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patientsQ33415505
SL-401 and SL-501, targeted therapeutics directed at the interleukin-3 receptor, inhibit the growth of leukaemic cells and stem cells in advanced phase chronic myeloid leukaemiaQ34098428
The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatmentQ37151676
Systemic mastocytosis in adults: 2013 update on diagnosis, risk stratification, and managementQ38110527
CD 123 is a membrane biomarker and a therapeutic target in hematologic malignanciesQ38186870
Failure to detect IL-3-binding sites on human mast cellsQ41714666
A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all thrQ42639273
Severe acute interstitial lung disease after crizotinib therapy in a patient with EML4-ALK-positive non-small-cell lung cancerQ44054776
A Phase 1 study of the safety, pharmacokinetics and anti-leukemic activity of the anti-CD123 monoclonal antibody CSL360 in relapsed, refractory or high-risk acute myeloid leukemia.Q51051082
Detection of molecular targets on the surface of CD34+/CD38-- stem cells in various myeloid malignancies.Q53646273
Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes.Q54447022
Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult miceQ70292216
P433issue7
P921main subjectmast cellQ191989
interleukinsQ194908
P304page(s)1605-1608
P577publication date2015-02-02
P1433published inLeukemiaQ6534498
P1476titleAberrant expression of CD123 (interleukin-3 receptor-α) on neoplastic mast cells.
P478volume29