Evidence for the differential effects of nucleocapsid protein on strand transfer in various regions of the HIV genome.

scientific article published on 20 February 2003

Evidence for the differential effects of nucleocapsid protein on strand transfer in various regions of the HIV genome. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M211701200
P698PubMed publication ID12595541

P2093author name stringJeffrey J DeStefano
Suchitra S Derebail
Megan J Heath
P2860cites workRetroviral Recombination and Reverse TranscriptionQ22242273
The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structureQ24534107
Optimal computer folding of large RNA sequences using thermodynamics and auxiliary informationQ24602467
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Spatial proximity of the HIV-1 nucleocapsid protein zinc fingers investigated by time-resolved fluorescence and fluorescence resonance energy transfer.Q52368747
The kissing hairpin sequence promotes recombination within the HIV-I 5' leader region.Q52543360
Zinc binding to the HIV-1 nucleocapsid protein: a thermodynamic investigation by fluorescence spectroscopyQ71028722
Retroviral recombination: what drives the switch?Q73626301
RNA secondary structure switching during DNA synthesis catalyzed by HIV-1 reverse transcriptaseQ73940248
Kinetic analysis of the effect of HIV nucleocapsid protein (NCp) on internal strand transfer reactionsQ77357856
A mechanism for plus-strand transfer enhancement by the HIV-1 nucleocapsid protein during reverse transcriptionQ27625600
A molecular rheostat. Co-operative rev binding to stem I of the rev-response element modulates human immunodeficiency virus type-1 late gene expressionQ28246434
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNAQ28279502
HIV-1: fifteen proteins and an RNAQ28284280
First glimpses at structure-function relationships of the nucleocapsid protein of retrovirusesQ28285187
On finding all suboptimal foldings of an RNA moleculeQ29547627
Human immunodeficiency virus type 1 nucleocapsid protein can prevent self-priming of minus-strand strong stop DNA by promoting the annealing of short oligonucleotides to hairpin sequencesQ33603932
Zinc finger structures in the human immunodeficiency virus type 1 nucleocapsid protein facilitate efficient minus- and plus-strand transferQ33604321
Point mutants of Moloney murine leukemia virus that fail to package viral RNA: evidence for specific RNA recognition by a "zinc finger-like" protein sequenceQ33669533
High rate of recombination throughout the human immunodeficiency virus type 1 genomeQ33793169
Specific zinc-finger architecture required for HIV-1 nucleocapsid protein's nucleic acid chaperone functionQ34065314
Homologous recombination promoted by reverse transcriptase during copying of two distinct RNA templatesQ34091760
RNA chaperones and the RNA folding problemQ34294471
Improved predictions of secondary structures for RNAQ34310064
Human immunodeficiency virus type 1 recombination: rate, fidelity, and putative hot spotsQ34355430
Mechanisms of retroviral recombinationQ34432232
Subtle alterations of the native zinc finger structures have dramatic effects on the nucleic acid chaperone activity of human immunodeficiency virus type 1 nucleocapsid proteinQ34999333
Thermodynamic stability and statistical significance of potential stem-loop structures situated at the frameshift sites of retrovirusesQ35239458
Copy-choice recombination by reverse transcriptases: reshuffling of genetic markers mediated by RNA chaperonesQ35772493
Retrovirus variation and reverse transcription: abnormal strand transfers result in retrovirus genetic variationQ36439044
Generation of diversity in retrovirusesQ36643346
Viral RNA annealing activities of human immunodeficiency virus type 1 nucleocapsid protein require only peptide domains outside the zinc fingersQ37111477
HIV-1 nucleocapsid protein induces "maturation" of dimeric retroviral RNA in vitroQ37427179
Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombinationQ37701269
Structure, Replication, and Recombination of Retrovirus Genomes: Some Unifying HypothesesQ37875366
HIV-1 nucleocapsid protein activates transient melting of least stable parts of the secondary structure of TAR and its complementary sequenceQ38290651
Strict conservation of the retroviral nucleocapsid protein zinc finger is strongly influenced by its role in viral infection processes: characterization of HIV-1 particles containing mutant nucleocapsid zinc-coordinating sequencesQ38326892
Catalysis of DNA reassociation by the Escherichia coli DNA binding protein: A polyamine-dependent reactionQ39176476
Interactions between HIV-1 nucleocapsid protein and viral DNA may have important functions in the viral life cycleQ40405392
Inhibitors of HIV nucleocapsid protein zinc fingers as candidates for the treatment of AIDS.Q41270026
Conformational behaviour of the active and inactive forms of the nucleocapsid NCp7 of HIV-1 studied by 1H NMR.Q41495032
Retroviral nucleocapsid proteins possess potent nucleic acid strand renaturation activity.Q41780912
Strand transfer mediated by human immunodeficiency virus reverse transcriptase in vitro is promoted by pausing and results in misincorporationQ42674918
HIV-1 nucleocapsid protein zinc finger structures induce tRNA(Lys,3) structural changes but are not critical for primer/template annealingQ44253743
C-terminal retroviral-type zinc finger domain from the HIV-1 nucleocapsid protein is structurally similar to the N-terminal zinc finger domainQ45068602
The nature of human immunodeficiency virus type 1 strand transfersQ45753451
The annealing of tRNA3Lys to human immunodeficiency virus type 1 primer binding site is critically dependent on the NCp7 zinc fingers structureQ45757764
Influence of human immunodeficiency virus nucleocapsid protein on synthesis and strand transfer by the reverse transcriptase in vitroQ45789166
Human immunodeficiency virus nucleocapsid protein stimulates strand transfer from internal regions of heteropolymeric RNA templatesQ45790185
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectviral nucleocapsidQ4384107
P304page(s)15702-15712
P577publication date2003-02-20
P1433published inJournal of Biological ChemistryQ867727
P1476titleEvidence for the differential effects of nucleocapsid protein on strand transfer in various regions of the HIV genome.
P478volume278

Reverse relations

cites work (P2860)
Q36684283Antiretroviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase increase template-switching frequency
Q43109836Effect of Mg(2+) and Na(+) on the nucleic acid chaperone activity of HIV-1 nucleocapsid protein: implications for reverse transcription
Q35891627Effects of nucleic acid local structure and magnesium ions on minus-strand transfer mediated by the nucleic acid chaperone activity of HIV-1 nucleocapsid protein
Q37149739Fidelity of plus-strand priming requires the nucleic acid chaperone activity of HIV-1 nucleocapsid protein
Q33716831Genetic recombination of human immunodeficiency virus type 1 in one round of viral replication: effects of genetic distance, target cells, accessory genes, and lack of high negative interference in crossover events
Q36804480In vitro synthesis of long DNA products in reactions with HIV-RT and nucleocapsid protein
Q44697751Insights into the multiple roles of pausing in HIV-1 reverse transcriptase-promoted strand transfers
Q53635184Mechanistic analysis of pause site-dependent and -independent recombinogenic strand transfer from structurally diverse regions of the HIV genome.
Q36258296Nucleic acid chaperone activity of HIV-1 nucleocapsid protein: critical role in reverse transcription and molecular mechanism
Q37086413Nucleocapsid protein function in early infection processes
Q34360226Pausing during reverse transcription increases the rate of retroviral recombination
Q37722585Retroviral reverse transcriptases
Q34775658Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription
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Q37086417Strand transfer events during HIV-1 reverse transcription
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Q59357291Template-primer binding affinity and RNase H cleavage specificity contribute to the strand transfer efficiency of HIV-1 reverse transcriptase
Q38021263The origin of genetic diversity in HIV-1.
Q35222868Zinc finger-dependent HIV-1 nucleocapsid protein-TAR RNA interactions

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