ESMO Open

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ESMO Open is …
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APC-free journalQ73365499
academic journalQ737498
open-access journalQ773668
society journalQ73364223
scientific journalQ5633421

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P8375Crossref journal ID300410
P6180Dimensions Source ID1159613
P5115Directory of Open Access Journals ID2059-7029
P8903HAL journal ID112260
P236ISSN2059-7029
P7363ISSN-L2059-7029
P1055NLM Unique ID101690685
P856official websitehttp://esmoopen.bmj.com/
https://esmoopen.bmj.com/front
P10283OpenAlex IDS4210217024
P12834PMC journal ID3084
P7662Scilit journal ID1999366
P1156Scopus source ID21100873339

P972catalogDirectory of Open Access JournalsQ1227538
P275copyright licenseCreative Commons Attribution-NonCommercialQ6936496
P17countryUnited States of AmericaQ30
United KingdomQ145
P495country of originUnited KingdomQ145
P8875indexed in bibliographic reviewScopusQ371467
Science Citation Index ExpandedQ104047209
P407language of work or nameEnglishQ1860
P127owned byEuropean Society for Medical OncologyQ5413188
P123publisherBMJQ2018873
P793significant eventcreated as open accessQ73375889
P1476titleESMO open

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Q1295879131 Obligatory tumour heterogeneity driven by Myc overexpression: mechanistic insights and therapeutic strategies
Q12958947210 Extracellular vesicles that carry signalling networks drive phenocopying of migratory behaviour between cancer cells in vivo
Q11387454311 ESMO 2021 breakthroughs: practicing oncologist’s perceptions on data presentation
Q12958946711 The heterogeneous genomic and immune landscapes of lethal metastatic breast cancer
Q12958885113 Exploring mechanisms of tumour lymphangiogenesis to potentiate immunotherapies in melanoma
Q12958585014 A patient derived antibody targeting the tetraspanin CD9 inhibits tumour progression and metastasis
Q12958897115 Identification of new combination therapies for lung cancer tumours harbouring KRAS mutations
Q12958656216 Quadruple vertical targeting of an oncogenic pathway as a treatment strategy to prevent drug resistance
Q12958560717 Quantifying microenvironmental signatures of oesophageal carcinogenesis
Q12958682418 Eosinophils are an integral part of the tumour microenvironment in colorectal cancer exerting potent anti-tumorigenic activities
Q12958865619 Autophagy induction as a new therapy for HER2+ breast tumorigenesis
Q12312240919P Long term sexual disorders among rare ovarian cancer survivors: The national GINECO case-control Vivrovaire Rare Tumors study
Q12958668420 Identification of combinatorial therapies with inhibitors of the PI3K pathway in PTEN-null tumours
Q944250772017 Thank you to our reviewers
Q557151002018 ESMO Sarcoma and GIST Symposium: 'take-home messages' in soft tissue sarcoma.
Q1301906322023 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting
Q12958583421 Defining the cell populations responsible for skin cancer initiation and relapse following therapy
Q12958847622 Luminal progenitor cells as a new target in castration-resistant prostate cancer (CRPC)
Q92024363223-Radium for metastatic osteosarcoma: combination therapy with other agents and external beam radiotherapy
Q12967398222P PD-L1 testing in mTNBC: Interplatform and interobserver reproducibility of CE-IVD assays for CPS and IC scores
Q12958763323 Evidence for antigen-driven TCRB chain convergence in the tumourinfiltrating t cell repertoire of 148 research subjects with melanoma
Q12957839423P Prognostic value of tumor-infiltrating lymphocytes (TILs) and soluble immune checkpoints in early triple-negative breast cancer (TNBC)
Q12966265324P Associating BRCA1 hypermethylation with clinicopathological and molecular variables in triple-negative breast cancer
Q12958685025 Strategies to overcome phenotype switch-driven therapy resistance in melanoma
Q12958736726 Overcoming the limitations of lung cancer radiotherapy by targeting the CD73/adenosine immune checkpoint
Q123123220263P Cross-sectional nationwide population-based study of living conditions, and identification of sexual and fertility profiles among young women after breast cancer in France: A study of the French Network of Cancer Registries (FRANCIM)
Q123123763265P UCATS: A national specialist service for integration of gender affirming and oncological care in transgender patients with breast cancer
Q12958665827 Visualise cancer cell dynamics of colorectal cancer progressionhj snippertsa rosenberg
Q12958803528 Stress signalling in breast cancer cells induces matrix components of stem cell niches that promote chemotherapy-resistant metastasis
Q12958675029 Radiation promotes transdifferentiation of glioblastoma stem cells into vascular cell types
Q1295894273 Clonal dynamics of colon carcinoma progression
Q5527889130 Immunotherapy in advanced NSCLC—from the ‘tsunami’ of therapeutic knowledge to a clinical practice algorithm: results from an international expert panel meeting of the Italian Association of Thoracic Oncology (AIOT).
Q12300282930 Whole-genome sequencing of normal stem cells provides novel insights into human native hematopoiesis and leukaemia aetiology
Q12958754031 Loss of P53 drives systemic neutrophilic inflammation in breast cancer
Q11567212832 Impact of colibactin-producing escherichia coli on immune microenvironment in preclinical colorectal cancer models
Q12958797033 PAN-cancer whole genome sequencing reveals patterns of subclonal mutations, signature changes and selection
Q12958906434 Gene fusions in 1,015 human cancer cell lines: integrating large-scale genomic data, high-throughput drug and CRISPR/Cas9 screens to assess functional relevance and therapeutic potential
Q1295881454 Patterns of clustered mutational processes: Pan-Cancer analysis of chromothripsis, chromoplexy and kataegis
Q1295870205 PIK3c2G loss promotes pancreatic cancer through MTOR regulation and metabolic rewiring
Q1295885406 Imaging tumour metabolism to guide treatment of breast cancer with drugs targeted at PI3K alpha
Q12322710761P The cysteine-rich protein 61 (Cyr61) contributes to tumor proliferation and invasion via HGF-mediated NF-kB signaling pathway in human hepatocellular carcinoma
Q1295866467 Evolution of cross-resistance to CD8+ T cells in the course of BRAF and MEK inhibitor treatment in BRAFV600E melanoma
Q1295887539 Liquid biopsy in small cell lung cancer (SCLC)
Q100394568A European survey on the insights of patients living with metastatic colorectal cancer: the patient journey before, during and after diagnosis - an Eastern European perspective
Q104745956A clinical validation study of MammaPrint in hormone receptor-positive breast cancer from the Austrian Breast and Colorectal Cancer Study Group 8 (ABCSG-8) biomarker cohort
Q55030434A consensus on liquid biopsy from the 2016 Chinese Lung Cancer Summit expert panel.
Q55025199A new era of oncology through artificial intelligence.
Q127174881A new schedule of one week on/one week off temozolomide as second-line treatment of advanced neuroendocrine carcinomas (TENEC-TRIAL): a multicenter, open-label, single-arm, phase II trial
Q92684907A phase Ib/II study of HER3-targeting lumretuzumab in combination with carboplatin and paclitaxel as first-line treatment in patients with advanced or metastatic squamous non-small cell lung cancer
Q54837286A prospective clinical trial to assess lapatinib effects on cutaneous squamous cell carcinoma and actinic keratosis.
Q53978383AIOM chooses ESMO Open-Cancer Horizons as its official journal: a warm welcome from ESMO Open.
Q58732118ALK IHC and FISH discordant results in patients with NSCLC and treatment response: for discussion of the question-to treat or not to treat?
Q54857752ASCO highlights podcast: head and neck cancers.
Q88646720ASCO: practice changing studies in gastrointestinal cancer
Q55009905Abiraterone: moving up in line?
Q91673669Achieving equal and timely access to innovative anticancer drugs in the European Union (EU): summary of a multidisciplinary CECOG-driven roundtable discussion with a focus on Eastern and South-Eastern EU countries
Q54986604Activating HER2 mutations as emerging targets in multiple solid cancers.
Q90603828Acute kidney injury from contrast-enhanced CT procedures in patients with cancer: white paper to highlight its clinical relevance and discuss applicable preventive strategies
Q102151746Addition of nivolumab to chemotherapy in patients with advanced gastric cancer: a relevant step ahead, but still many questions to answer
Q96949659Adjuvant and neoadjuvant therapies in melanoma
Q55064633Adjuvant treatment following radical cystectomy for muscle-invasive urothelial carcinoma and variant histologies: Is there a role for radiotherapy?
Q55647987Admission of critically ill patients with cancer to the ICU: many uncertainties remain.
Q92980890Advancing molecular tumour boards: highly needed to maximise the impact of precision medicine
Q59333303All change: closing the gender gap in oncology
Q102151744An evaluation of self-perceived knowledge, attitudes and behaviours of UK oncologists about LGBTQ+ patients with cancer
Q92090909Announcing the ESMO Open special issue on upcoming molecular targets for cancer treatment
Q55072300Anti-PD-1/anti-PD-L1 immunotherapy versus docetaxel for previously treated advanced non-small cell lung cancer: a systematic review and meta-analysis of randomised clinical trials.
Q55364590Antithrombotic therapy for prophylaxis and treatment of venous thromboembolism in patients with cancer: review of the literature on current practice and emerging options.
Q99204236Application of the ESMO-Magnitude of Clinical Benefit Scale (V.1.1) to the field of early breast cancer therapies
Q55026606Applying the ESMO-Magnitude of Clinical Benefit Scale in real life.
Q112701357Artificial intelligence for detection of microsatellite instability in colorectal cancer-a multicentric analysis of a pre-screening tool for clinical application
Q92972185Assessing molecular subtypes of gastric cancer: microsatellite unstable and Epstein-Barr virus subtypes. Methods for detection and clinical and pathological implications
Q114668981Assessment of the clinical and cost-effectiveness evidence in the reimbursement decisions of new cancer drugs
Q54647675Association between bevacizumab-related hypertension and response to treatment in patients with metastatic colorectal cancer.
Q55027355Association of baseline absolute neutrophil counts and survival in patients with metastatic colorectal cancer treated with second-line antiangiogenic therapies: exploratory analyses of the RAISE trial and validation in an electronic medical record d
Q90861328Association of homogeneous inflamed gene signature with a better outcome in patients with metastatic melanoma treated with MAGE-A3 immunotherapeutic
Q95324139Association of programmed cell death ligand 1 and circulating lymphocytes with risk of venous thromboembolism in patients with glioma
Q102210211Atezolizumab in metastatic triple-negative breast cancer: IMpassion130 and 131 trials - how to explain different results?
Q91047162Atypical haemolytic-uraemic syndrome in patient with metastatic colorectal cancer treated with fluorouracil and oxaliplatin: a case report and a review of literature
Q100761050Aurora kinases in ovarian cancer
Q91710470Awareness of predatory journals and open access among medical oncologists: results of an online survey
Q91737294Awareness of predatory publishing
Q90292001B7x-from bench to bedside
Q57299887BET bromodomain inhibitor birabresib in mantle cell lymphoma: in vivo activity and identification of novel combinations to overcome adaptive resistance
Q55080436BRCA mutation carrier detection. A model-based cost-effectiveness analysis comparing the traditional family history approach and the testing of all patients with breast cancer.
Q54227107Back to the 'essence' of medical treatment in oncology: the 2015 WHO Model List of Essential Medicines.
Q64114213Benefit from anti-EGFRs in and wild-type metastatic transverse colon cancer: a clinical and molecular proof of concept study
Q90861340Benefit of adjuvant chemotherapy based on lymph node involvement for oesophageal cancer following trimodality therapy
Q114877537Benefit of pazopanib in advanced gastrointestinal stromal tumours: results from a phase II trial (SSG XXI, PAGIST)
Q111434622Beta-blockers in early-stage breast cancer: a systematic review and meta-analysis
Q55224120Between January 2009 and April 2016, 134 novel anticancer therapies were approved: what is the level of knowledge concerning the clinical benefit at the time of approval?
Q120496159Beyond the lessons learned from the COVID-19 pandemic: opportunities to optimize clinical trial implementation in oncology
Q54958979Biologics and biosimilars: what, why and how?
Q55000770Biology of premature ageing in survivors of cancer.
Q54974112Biosimilars as a strategy to improve sustainability.
Q59138150Biosimilars in oncology
Q55007675Biosimilars.
Q54135887Biosimilars: a position paper of the European Society for Medical Oncology, with particular reference to oncology prescribers.
Q101563759Body weight and return to work among survivors of early-stage breast cancer
Q90711328Bone health management in the continuum of prostate cancer disease: a review of the evidence with an expert panel opinion
Q98574865Brain microenvironment-driven resistance to immune and targeted therapies in acral melanoma
Q102058745Bratislava Statement: consensus recommendations for improving pancreatic cancer care
Q99207281Breast Cancer: global quality care optimizing care delivery with existing financial and personnel resources
Q104745973Breast cancer in very young women-a multicenter 10-year experience
Q100453951Breast cancer subtypes: implications for the treatment and survival of patients in Africa-a prospective cohort study from Mozambique
Q94597520Brief letter of a doctor to his psychologist in the COVID-19 outbreak era
Q97519696Buparlisib plus carboplatin or lomustine in patients with recurrent glioblastoma: a phase Ib/II, open-label, multicentre, randomised study
Q102141013CDK4/6 inhibition in HR-positive early breast cancer: are we putting all eggs in one basket?
Q91673689CDK4/6 inhibition in low burden and extensive metastatic breast cancer: summary of an ESMO Open-Cancer Horizons pro and con discussion
Q57107726CDK4/6 inhibitors in the treatment of patients with breast cancer: summary of a multidisciplinary round-table discussion
Q54986756CECOG educational illustrations: the blood-brain barrier and its relevance for targeted cancer therapies and immuno-oncology.
Q101409692COVID-19 risk for patients undergoing anticancer treatment at the outpatient clinic of the National Cancer Institute of Milan: the COVINT study
Q55362219CSCO joins ESMO Open-Cancer Horizons.
Q64958984CSF-1 and Ang-2 serum levels - prognostic and diagnostic partners in non-small cell lung cancer.
Q94547845Call for ensuring cancer care continuity during COVID-19 pandemic
Q98621903Calling for advocacy, education and public policy actions on pain control for patients with cancer in Africa
Q97526280Can multigene assays widen their clinical usefulness in early breast cancer treatment choice during the current COVID-19 outbreak in Italy?
Q28069620Can we predict toxicity and efficacy in older patients with cancer? Older patients with colorectal cancer as an example
Q28068579Cancer and liver cirrhosis: implications on prognosis and management
Q54969186Cancer and the arts: Johannes Brahms and the problem of pancreatic carcinoma.
Q54839129Cancer and the arts: La Madonna dei Tumori, Ravenna, Italy.
Q58757735Cancer and the arts: a Pacifist's Guide to the War on Cancer
Q89494920Cancer and the arts: how often do doctors only see what they want to see? Or: the case of an 'epidemic of breast cancer among famous artists'
Q54974731Cancer and the arts: metastasis-as perceived through the ages.
Q88863399Cancer and the arts: the fight for meaning - Akira Kurosawa's "Ikiru"
Q55060960Cancer and the arts: why we need works by long-term survivors.
Q90765494Cancer care during the spread of coronavirus disease 2019 (COVID-19) in Italy: young oncologists' perspective
Q122941516Cancer care in transgender and gender-diverse persons: results from two national surveys among providers and health service users by the Italian Association of Medical Oncology
Q28072071Cancer clinical research in Latin America: current situation and opportunities. Expert opinion from the first ESMO workshop on clinical trials, Lima, 2015
Q95837704Cancer datasets and the SARS-CoV-2 pandemic: establishing principles for collaboration
Q54896960Cancer drugs, survival and ethics: a critical look from the inside.
Q54260838Cancer genome: highlights of a Nature Medicine perspective.
Q54055141Cancer immune cycle: a video introduction to the interaction between cancer and the immune system.
Q28076763Cancer in pregnancy: disentangling treatment modalities
Q92684886Cancer medicines in Asia and Asia-Pacific: What is available, and is it effective enough?
Q60933076Cancer research in the era of immunogenomics
Q55209489Carboplatin dose based on actual renal function: no excess of acute haematotoxicity in adjuvant treatment in seminoma stage I.
Q55438414Cardiotoxicity of immune checkpoint inhibitors.
Q89807860Cardiotoxicity of trastuzumab given for 12 months compared to shorter treatment periods: a systematic review and meta-analysis of six clinical trials
Q92972179Care of adolescents and young adults with cancer in Asia: results of an ESMO/SIOPE/SIOP Asia survey
Q54975074Career opportunities and benefits for young oncologists in the European Society for Medical Oncology (ESMO).
Q99608128Caring for the caregiver: a systematic review characterising the experience of caregivers of older adults with advanced cancers
Q54581789Case report: impressive response to pembrolizumab in a patient with mismatch-repair deficient metastasized colorectal cancer and bulky disease.
Q28069040Challenge of cancer in the elderly
Q90861333Challenge of implementing clinical practice guidelines. Getting ESMO's guidelines even closer to the bedside: introducing the ESMO Practising Oncologists' checklists and knowledge and practice questions
Q123308105Challenges in oncology career: are we closing the gender gap? Results of the new ESMO Women for Oncology Committee survey
Q64094659Changes in Recurrence Score by neoadjuvant endocrine therapy of breast cancer and their prognostic implication
Q112701354Characterizing kinase intergenic-breakpoint rearrangements in a large-scale lung cancer population and real-world clinical outcomes
Q54988181Checkpoint inhibitors in the treatment of urological malignancies.
Q123347576Checkpoint inhibitors, fertility, pregnancy, and sexual life: a systematic review
Q54962992Chemotherapy in cancer patients undergoing haemodialysis: a nationwide study in Japan.
Q90050818Chemotherapy plus bevacizumab as an optimal first-line therapeutic treatment for patients with right-sided metastatic colon cancer: a meta-analysis of first-line clinical trials
Q90573071Chemotherapy versus erlotinib as second-line treatment in patients with advanced non-small cell lung cancer and wild-type epidermal growth factor receptor: an individual patient data (IPD) analysis
Q90299761Choosing wisely in oncology: necessity and obstacles
Q54983901Circulating cell-free plasma tumour DNA shows a higher incidence of EGFR mutations in patients with extrathoracic disease progression.
Q55385744Clinical activity and tolerability of FOLFIRI and cetuximab in elderly patients with metastatic colorectal cancer in the CAPRI-GOIM first-line trial.
Q64889458Clinical and molecular determinants of extrahepatic disease progression in patients with metastatic colorectal cancer with liver-limited metastases deemed initially unresectable.
Q104745969Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future
Q128179198Clinical benefit of anti-PD-(L)1 immunotherapies in advanced cancer in France: a population-based estimate from 2014 to 2021
Q91710464Clinical insights on outcomes of corticosteroid administration in immune checkpoint inhibitor-induced pneumonitis by retrospective case series analysis
Q55080669Clinical outcome and molecular characterisation of chemorefractory metastatic colorectal cancer patients with long-term efficacy of regorafenib treatment.
Q55294897Clinical outcome of patients with chemorefractory metastatic colorectal cancer treated with trifluridine/tipiracil (TAS-102): a single Italian institution compassionate use programme.
Q98574868Clinical outcomes of patients with breast cancer relapsing after (neo)adjuvant trastuzumab and receiving trastuzumab rechallenge or lapatinib-based therapy: a multicentre retrospective cohort study
Q100533131Clinical research disruption in the post-COVID-19 era: will the pandemic lead to change?
Q90437266Clinical scoring system for the prediction of survival of patients with advanced gastric cancer
Q102210204Clinical significance of ERBB2 exon 16 skipping: analysis of a real-world retrospective observational cohort study
Q55033775Clinical value of early detection of circulating tumour DNA-BRAFV600mut in patients with metastatic melanoma treated with a BRAF inhibitor.
Q54849840Clonal evolution and KRAS-MET coamplification during secondary resistance to EGFR-targeted therapy in metastatic colorectal cancer.
Q104745961Clonal evolution in diffuse large B-cell lymphoma with central nervous system recurrence
Q55265741Clonal evolution of colorectal cancer in a patient with serially resected metastases and liquid biopsies: a case report and discussion of the literature.
Q98732998Combinations in the first-line treatment of patients with advanced/metastatic renal cell cancer: regulatory aspects
Q91673696Community-driven development of a modified progression-free survival ratio for precision oncology
Q99233442Comparative analysis of antibiotic exposure association with clinical outcomes of chemotherapy versus immunotherapy across three tumour types
Q54989492Comparing assessment frameworks for cancer drugs between Canada and Europe: What can we learn from the differences?
Q114180883Comparison of actionable events detected in cancer genomes by whole-genome sequencing, in silico whole-exome and mutation panels
Q99616291Comparison of three commercial decision support platforms for matching of next-generation sequencing results with therapies in patients with cancer
Q102141007Completion rate and impact on physician-patient relationship of video consultations in medical oncology: a randomised controlled open-label trial
Q54116611Comprehensive molecular screening by next generation sequencing reveals a distinctive mutational profile of KIT/PDGFRA genes and novel genomic alterations: results from a 20-year cohort of patients with GIST from north-western Greece.
Q55186392Concerning the article by Louveau et al "Clinical value of early detection of circulating tumour DNA BRAFV600mut in patients with metastatic melanoma treated with a BRAF inhibitor".
Q55366227Concerns with conclusions in the article by Sherwood et al 'Key differences between 13 KRAS mutation detection technologies and their relevance for clinical practice'.
Q55022999Consensus on management of metastatic colorectal cancer in Central America and the Caribbean: San José, Costa Rica, August 2016.
Q55022893Contemporary outcomes from the use of regular imaging to detect relapse in high-risk cutaneous melanoma.
Q54143053Continuing EGFR-TKI beyond radiological progression in patients with advanced or recurrent, EGFR mutation-positive non-small-cell lung cancer: an observational study.
Q91710482Contrasting evidence to reimbursement reality for off-label use (OLU) of drug treatments in cancer care: rationale and design of the CEIT-OLU project
Q55686663Controversies and consensus of neoadjuvant chemotherapy in soft-tissue sarcomas.
Q64880678Controversies in oncology: are genomic tests quantifying homologous recombination repair deficiency (HRD) useful for treatment decision making?
Q55517923Controversies in oncology: surgery for small cell lung cancer? It's time to rethink the case.
Q54974390Controversies in oncology: which adjuvant endocrine therapy is to be given to premenopausal patients with hormone receptor-positive breast cancer?
Q129716018Controversies in upper GI oncology: MSI-H in gastroesophageal adenocarcinoma
Q88886302Correction
Q64107060Correction:
Q98574862Correction: Bone health management in the continuum of prostate cancer disease: a review of the evidence with an expert panel opinion
Q90156135Correction: European society for medical oncology (ESMO) 2018 Congress Twitter analysis: from ethics to results through the understanding of communication and interaction flows
Q95324183Correction: Feasibility of next-generation sequencing in clinical practice: results of a pilot study in the Department of Precision Medicine at the University of Campania 'Luigi Vanvitelli'
Q89900672Correction: Key differences between 13 KRAS mutation detection technologies and their relevance for clinical practice
Q103825792Correction: Mentoring as an opportunity to improve research and cancer care in Latin America (AAZPIRE project)
Q98906140Correction: Molecular profile of BRCA-mutated biliary tract cancers
Q100944711Correction: Oncological care organisation during COVID-19 outbreak
Q90789915Correction: PO-194 Novel potential targets for hakai oncogene during tumour progression
Q58698381Correction: Preparing for the incoming wave of biosimilars in oncology
Q96124418Correction: STK11 and KEAP1 mutations as prognostic biomarkers in an observational real-world lung adenocarcinoma cohort
Q92972173Correction: Sequential HER2 blockade as effective therapy in chemorefractory, HER2 gene-amplified, RAS wild-type, metastatic colorectal cancer: learning from a clinical case
Q92771625Correction: Tumour location and efficacy of first-line EGFR inhibitors in KRAS/RAS wild-type metastatic colorectal cancer: retrospective analyses of two phase II randomised Spanish TTD trials
Q123291497Corrigendum to ‘Checkpoint inhibitors, fertility, pregnancy, and sexual life: a systematic review’
Q28072563Critically ill patients with cancer: chances and limitations of intensive care medicine-a narrative review
Q90437250Current challenges in the implementation of precision oncology for the management of metastatic colorectal cancer
Q90659935Current models, challenges and best practices for work conducted between European academic cooperative groups and industry
Q98575133Current status and future potential of predictive biomarkers for immune checkpoint inhibitors in gastric cancer
Q92972106Cyclin D1 differential activation and its prognostic impact in patients with advanced breast cancer treated with trastuzumab
Q55008951Descriptive statistical analysis of a real life cohort of 2419 patients with brain metastases of solid cancers.
Q94552591Desmoid tumours: a perfect example for making progress in treatment management through international collaboration
Q54981288Detailed statistical assessment of the characteristics of the ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS) threshold rules.
Q99616289Detection of postoperative plasma circulating tumour DNA and lack of CDX2 expression as markers of recurrence in patients with localised colon cancer
Q98648097Development of circulating tumour DNA analysis for gastrointestinal cancers
Q92241725Development of new therapies for metastatic pancreatic cancer: are they better than FOLFIRINOX?
Q64087179Development of sodium fluoride PET response criteria for solid tumours (NAFCIST) in a clinical trial of radium-223 in osteosarcoma: from RECIST to PERCIST to NAFCIST
Q28076646Diagnosis and treatment of bone metastasis: comprehensive guideline of the Japanese Society of Medical Oncology, Japanese Orthopedic Association, Japanese Urological Association, and Japanese Society for Radiation Oncology
Q114190952Diagnostic work-up and systemic treatment for advanced non-squamous non-small-cell lung cancer in four Southeast Asian countries
Q55408178Differential research impact in cancer practice guidelines' evidence base: lessons from ESMO, NICE and SIGN.
Q122416458Dignity of science and the use of ChatGPT as a co-author
Q54522529Discussing and prescribing expensive unfunded anticancer drugs in Australia.
Q101563762Discussing motherhood when the oncological prognosis is dire: ethical considerations for physicians
Q55025094Do patients with reduced or excellent performance status derive the same clinical benefit from novel systemic cancer therapies? A systematic review and meta-analysis.
Q54912094Does clinical trial participation improve outcomes in patients with ovarian cancer?
Q59327186Dose escalation of axitinib on disease progression as a strategy in the treatment of metastatic renal cell carcinoma
Q54947553Drug development: successes, problems and pitfalls-the industry perspective.
Q92771675EHA evaluation of the ESMO-Magnitude of Clinical Benefit Scale version 1.1 (ESMO-MCBS v1.1) for haematological malignancies
Q28066272ESMO - Magnitude of Clinical Benefit Scale V.1.0 questions and answers
Q27928062ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016
Q58694200ESMO 2018 presidential symposium—IMpassion130: atezolizumab+nab-paclitaxel in triple-negative breast cancer
Q94561146ESMO Clinical Research Observatory (ECRO): improving the efficiency of clinical research through rationalisation of bureaucracy
Q55547427ESMO Copenhagen 2016: a lung cancer 'grand cru'.
Q54943251ESMO Leaders Generation Programme: an alumni insight.
Q95318554ESMO Management and treatment adapted recommendations in the COVID-19 era: Breast Cancer
Q96683040ESMO Management and treatment adapted recommendations in the COVID-19 era: Lung cancer
Q95321756ESMO Management and treatment adapted recommendations in the COVID-19 era: Pancreatic Cancer
Q94590733ESMO Open special series on new emerging targets in cancer immunotherapy
Q55091196ESMO Open welcomes the association with the Japanese Society of Medical Oncology (JSMO).
Q54836371ESMO Open-Cancer Horizons and the future of oncology.
Q94669593ESMO Open: news in breast cancer 2019
Q54945984ESMO Women for Oncology 2016: a very personal tale of my professional life in Asia.
Q54866473ESMO and WHO: 14 years of working in partnership on cancer control.
Q126387421ESMO expert consensus statements on the screening and management of financial toxicity in patients with cancer
Q28079204ESMO gave me a chance to help make a difference: a personal reflection on the occasion of receiving the 2015 ESMO Award
Q95837626ESMO management and treatment adapted recommendations in the COVID-19 era: colorectal cancer
Q97901462ESMO management and treatment adapted recommendations in the COVID-19 era: gynaecological malignancies
Q90437278ESMO presidential symposium wrap up: the ClarIDHy trial
Q91047170ESMO-Magnitude of Clinical Benefit Scale (MCBS) group
Q104745962ESMO20 YO for YO: highlights on adjuvant CDK4/6 inhibitors in early hormone receptor-positive/HER2-negative breast cancer
Q104745963ESMO20 YO for YO: highlights on immune checkpoint blockade for triple-negative breast cancer
Q104745967ESMO20 YO for YO: highlights on metastatic NSCLC-Keynote 024 update
Q104745970ESMO20 YO for YO: highlights on metastatic renal cell carcinoma-the CheckMate-9ER trial
Q104745964ESMO20 YO for YO: highlights on new drugs in advanced breast cancer focusing on sacituzumab govitecan and alpelisib
Q104745971ESMO20 YO for YO: highlights on oncogene-addicted NSCLC
Q104745968ESMO20 YO for YO: highlights on upper GI tumours
Q64094655Early use of steroids affects immune cells and impairs immunotherapy efficacy
Q94518825Editorial debate: Challenges an oncologist has to face during the SARS-CoV-2 pandemic within a universal healthcare system
Q94518828Editorial debate: Challenges we oncologists, working within a universal healthcare system, have to face in these hard times
Q54839303Editorial on an international survey of androgen deprivation therapy (ADT) for non-metastatic prostate cancer in 19 countries.
Q92241720Educational needs in gastrointestinal cancer: a consensus position paper from the ESMO Gastrointestinal Cancer Faculty
Q55402649Educational video: the role of PD-L1 in the local tumour microenvironment.
Q98575125Effect of trifluridine/tipiracil in patients treated in RECOURSE by prognostic factors at baseline: an exploratory analysis
Q55411853Effects of physical activity on depressive symptoms during breast cancer survivorship: a meta-analysis of randomised control trials.
Q58694204Efficacy and safety of ramucirumab-containing chemotherapy in patients with pretreated metastatic gastric neuroendocrine carcinoma
Q54878242Efficacy and toxicity of adjuvant chemotherapy in elderly patients with colorectal cancer: the ACCORE study.
Q113874542Efficacy, safety and quality-of-life data from patients with pre-treated metastatic colorectal cancer receiving trifluridine/tipiracil: results of the TALLISUR trial
Q90291969Elevated CRP levels indicate poor progression-free and overall survival on cancer patients treated with PD-1 inhibitors
Q55026060Emerging challenges of advanced squamous cell lung cancer.
Q55308858Empirical antimicrobial treatment in haemato-/oncological patients with neutropenic sepsis.
Q113874538Encorafenib plus cetuximab with or without binimetinib in patients with BRAF V600E-mutated metastatic colorectal cancer: real-life data from an Italian multicenter experience
Q98732996Endocrine therapy-based treatments in hormone receptor-positive/HER2-negative advanced breast cancer: systematic review and network meta-analysis
Q99247187Entrectinib approval by EMA reinforces options for ROS1 and tumour agnostic NTRK targeted cancer therapies
Q58801444Epigenetic biomarkers in cancer
Q54963093Eribulin for metastatic breast cancer (MBC) treatment: a retrospective, multicenter study based in Campania, south Italy (Eri-001 trial).
Q55261645Erlotinib intercalating pemetrexed/cisplatin versus erlotinib alone in Chinese patients with brain metastases from lung adenocarcinoma: a prospective, non-randomised, concurrent controlled trial (NCT01578668).
Q54438811Essentials for clinicians: head and neck tumours and neuro-oncology.
Q55346468European Medicines Agency approval summary: Zaltrap for the treatment of patients with oxaliplatin-resistant metastatic colorectal cancer.
Q102058740European Medicines Agency extension of indication to include the combination immunotherapy cancer drug treatment with nivolumab (Opdivo) and ipilimumab (Yervoy) for adults with intermediate/poor-risk advanced renal cell carcinoma
Q90292016European Medicines Agency review of ixazomib (Ninlaro) for the treatment of adult patients with multiple myeloma who have received at least one prior therapy
Q94552587European Medicines Agency review of midostaurin (Rydapt) for the treatment of adult patients with acute myeloid leukaemia and systemic mastocytosis
Q90060372European Society for Medical Oncology (ESMO) 2018 Congress Twitter analysis: from ethics to results through the understanding of communication and interaction flows
Q95324186Evaluation of nutritional status in non-small-cell lung cancer: screening, assessment and correlation with treatment outcome
Q101120496Evaluation of the contribution of randomised cancer clinical trials evaluating agents without documented single-agent activity
Q98733000Evaluation of the use and efficacy of (neo)adjuvant chemotherapy in angiosarcoma: a multicentre study
Q60049458Evaluation of time to failure of strategy as an alternative surrogate endpoint in patients with lung cancer with EGFR mutations
Q90291980Ex vivo lung cancer spheroids resemble treatment response of a patient with NSCLC to chemotherapy and immunotherapy: case report and translational study
Q104457245Examining policy cohesion for cervical cancer worldwide: analysis of WHO country reports
Q91641997Expanding the TNM for cancers of the colon and rectum using machine learning: a demonstration
Q55135199Exploration of time points and cut-off values for early tumour shrinkage to predict survival outcomes of patients with metastatic colorectal cancer treated with first-line chemotherapy using a biexponential model for change in tumour size.
Q92006283Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer
Q100533128Exploratory analysis of circulating cytokines in patients with metastatic breast cancer treated with eribulin: the TRANSERI-GONO (Gruppo Oncologico del Nord Ovest) study
Q92771659Exploratory analysis of front-line therapies in REVEL: a randomised phase 3 study of ramucirumab plus docetaxel versus docetaxel for the treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy
Q90291956Exploratory findings from a prematurely closed international, multicentre, academic trial: RAVELLO, a phase III study of regorafenib versus placebo as maintenance therapy after first-line treatment in RAS wild-type metastatic colorectal cancer
Q55286218Exploratory pooled analysis evaluating the effect of sequence of biological therapies on overall survival in patients with RAS wild-type metastatic colorectal carcinoma.
Q91047168Extension of the European Medicines Agency (EMA) approval of trifluridine/tipiracil for gastric cancer
Q55058184External quality assessment for EGFR mutations in Italy: improvements in performances over the time.
Q58757748Extra cost of brain metastases (BM) in patients with non-squamous non-small cell lung cancer (NSCLC): a French national hospital database analysis
Q55384042Extrapolation concept at work with biosimilar: a decade of experience in oncology.
Q101120491FOLFIRINOX or FOLFOXIRI in locally advanced duodenal adenocarcinoma: are we missing out?
Q101225152FOLFOXIRI plus bevacizumab versus FOLFOX plus bevacizumab for patients with metastatic colorectal cancer and ≥3 circulating tumour cells: the randomised phase III VISNÚ-1 trial
Q102210216Factors associated with the aggressiveness of care at the end of life for patients with cancer dying in hospital: a nationwide retrospective cohort study in mainland Portugal
Q64062061Factors associated with treatment delay in women with primary breast cancer who were referred to reproductive specialists
Q92771652Familial adenomatosis polyposis-related desmoid tumours treated with low-dose chemotherapy: results from an international, multi-institutional, retrospective analysis
Q97881742Feasibility of high-throughput sequencing in clinical routine cancer care: lessons from the cancer pilot project of the France Genomic Medicine 2025 plan
Q90801758Feasibility of next-generation sequencing in clinical practice: results of a pilot study in the Department of Precision Medicine at the University of Campania 'Luigi Vanvitelli'
Q91641991Female oncologists in the Middle East and North Africa: progress towards gender equality
Q113874544Final efficacy and safety data, and exploratory molecular profiling from the phase III ALUR study of alectinib versus chemotherapy in crizotinib-pretreated ALK-positive non-small-cell lung cancer
Q54986606Final results of the large-scale multinational trial PROFILE 1005: efficacy and safety of crizotinib in previously treated patients with advanced/metastatic ALK-positive non-small-cell lung cancer.
Q103825787First results of the EORTC-SPECTA/Arcagen study exploring the genomics of rare cancers in collaboration with the European reference network EURACAN
Q101049993First-in-human pharmacokinetics of tamoxifen and its metabolites in the milk of a lactating mother: a case study
Q104457246First-line PARP inhibitors in ovarian cancer: summary of an ESMO Open - Cancer Horizons round-table discussion
Q92771667First-line and second-line treatment of patients with metastatic pancreatic adenocarcinoma in routine clinical practice across Europe: a retrospective, observational chart review study
Q97529671Five-year review of corticosteroid duration and complications in the management of immune checkpoint inhibitor-related diarrhoea and colitis in advanced melanoma
Q64229197Flucelvax Tetra: a surface antigen, inactivated, influenza vaccine prepared in cell cultures
Q54238201Four distinct immune microenvironment subtypes in gastric adenocarcinoma with special reference to microsatellite instability.
Q90291994From crizotinib to lorlatinib: continuous improvement in precision treatment of ALK-positive non-small cell lung cancer
Q98575122Gemcitabine/nab-paclitaxel with pamrevlumab: a novel drug combination and trial design for the treatment of locally advanced pancreatic cancer
Q55362111Gender and outcomes in non-small cell lung cancer: an old prognostic variable comes back for targeted therapy and immunotherapy?
Q98574053Gender and sex disparity in cancer trials
Q94472862Gender climate in Indian oncology: national survey report
Q97417114Gender gap: surveying the world for tomorrow
Q58694191Gender influence on professional satisfaction and gender issue perception among young oncologists. A survey of the Young Oncologists Working Group of the Italian Association of Medical Oncology (AIOM)
Q122957679Gender influence on work satisfaction and leadership for medical oncologists: a survey of the Spanish Society of Medical Oncology (SEOM)
Q122966448Gender representation on editorial boards of leading oncology journals
Q57071160Gender-related challenges facing oncologists: the results of the ESMO Women for Oncology Committee survey
Q101224970Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer
Q101049965Gender-specific aspects related to type of fertility preservation strategies and access to fertility care
Q91047158Genetic mapping of pancreatic cancer by targeted next-generation sequencing in a cohort of patients managed with nab-paclitaxel-based chemotherapy or agents targeting the EGFR axis: a retrospective analysis of the Hellenic Cooperative Oncology Group
Q64111570Genomic heterogeneity and efficacy of PI3K pathway inhibitors in patients with gynaecological cancer
Q90050897Genomic-guided precision therapy for soft tissue sarcoma
Q55100041Genotyping tumour DNA in cerebrospinal fluid and plasma of a HER2-positive breast cancer patient with brain metastases.
Q104745952Germinal BRCA1-2 pathogenic variants (gBRCA1-2pv) and pancreatic cancer: epidemiology of an Italian patient cohort
Q55035816Global cancer control: responding to the growing burden, rising costs and inequalities in access.
Q128788352Guidelines for the diagnosis and treatment of cutaneous squamous cell carcinoma: a GRADE approach for evidence evaluation and recommendations by the Italian Association of Medical Oncology
Q92241712HER2-targeted therapy should be shifted towards an earlier line for patients with anti-EGFR-therapy naïve, HER2-amplified metastatic colorectal cancer
Q100958295Haematopoietic stem cell transplantation in adult soft-tissue sarcoma: an analysis from the European Society for Blood and Marrow Transplantation
Q54867398Hallmarks of glioblastoma: a systematic review.
Q55152175Health-related quality of life in a randomised phase III study of gemcitabine plus S-1, S-1 alone and gemcitabine alone for locally advanced or metastatic pancreatic cancer: GEST study.
Q102378013Healthcare use and costs in early breast cancer: a patient-level data analysis according to stage and breast cancer subtype
Q89494887Heterogeneity of colon cancer: from bench to bedside
Q90861314High incidence of cetuximab-related infusion reactions in head and neck patients
Q28075787Highlights for ESMO 40: celebration review for lifetime achievement awards
Q54978882Highlights from the San Antonio Breast Cancer Symposium 2015.
Q55176173Highlights in breast cancer from ASCO 2016.
Q89700296Highlights in lung cancer in 2019
Q98234990Hormonal control of cancer: an outdated topic?
Q92684950How I treat ALK-positive non-small cell lung cancer
Q98158289How I treat MALT lymphoma: 'a subjective interpretation of the gospel according to Isaacson….'
Q64944737How I treat MSI cancers with advanced disease.
Q91710508How I treat NTRK gene fusion-positive cancers
Q98664561How I treat adverse effects of CAR-T cell therapy
Q98944489How I treat anal squamous cell carcinoma
Q90292021How I treat anaplastic glioma without 1p/19q codeletion
Q64890286How I treat cancer special issue.
Q92771647How I treat cancer-associated thrombosis
Q92684962How I treat cancer: treatment of rheumatological side effects of immunotherapy
Q64900660How I treat cancers of unknown primary.
Q92241733How I treat gastric adenocarcinoma
Q90198734How I treat malignant pleural mesothelioma
Q92684942How I treat metastatic melanoma
Q92972224How I treat metastatic triple-negative breast cancer
Q98575136How I treat neuroendocrine tumours
Q98575147How I treat pancreatic cancer
Q90292027How I treat squamous ENT cancer
Q55316580How many diseases is triple negative breast cancer: the protagonism of the immune microenvironment.
Q54965602How shall we treat early triple-negative breast cancer (TNBC): from the current standard to upcoming immuno-molecular strategies.
Q104745960How we treat endocrine complications of immune checkpoint inhibitors
Q91812608How we treat glioblastoma
Q98575144How we treat metastatic colorectal cancer
Q92684971How we treat neurological toxicity from immune checkpoint inhibitors
Q94684157How we treat patients with brain tumour during the COVID-19 pandemic
Q64955303How we treat patients with leptomeningeal metastases.
Q94684154How we treat patients with lung cancer during the SARS-CoV-2 pandemic
Q91554260How we treat patients with lung cancer during the SARS-CoV-2 pandemic: primum non nocere
Q64939865Hyperprogressive disease during nivolumab or irinotecan treatment in patients with advanced gastric cancer.
Q55080476I-SPY 2: optimising cancer drug development in the 21st century.
Q122969789Identifying and preventing burnout in young oncologists, an overwhelming challenge in the COVID-19 era: a study of the Spanish Society of Medical Oncology (SEOM)
Q28079771Immune checkpoint blockade in small cell lung cancer: is there a light at the end of the tunnel?
Q54966701Immune checkpoint inhibition-related colitis: symptoms, endoscopic features, histology and response to management.
Q91812593Immune checkpoint inhibitor treatment in patients with oncogene- addicted non-small cell lung cancer (NSCLC): summary of a multidisciplinary round-table discussion
Q55082051Immune checkpoint inhibitors for advanced non-small cell lung cancer: emerging sequencing for new treatment targets.
Q57822393Immune checkpoint inhibitors for every patient with non-small cell lung cancer? Update on immunotherapy in patients with lung cancer
Q88646657Immune checkpoint inhibitors in lung cancer: the holy grail has not yet been found…
Q88762624Immune-related response criteria: light and shadows
Q90711347Immunohistochemical validation study of 15-gene biomarker panel predictive of benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of JBR.10
Q104745966Immunological inflammatory biomarkers as prognostic predictors for advanced hepatocellular carcinoma
Q60960900Immunotherapy for hepatocellular carcinoma: current status and future perspectives
Q55308068Immunotherapy in lung cancer.
Q100958296Impact of COVID-19 on anxiety levels among patients with cancer actively treated with systemic therapy
Q103825791Impact of COVID-19 on cancer service delivery: results from an international survey of oncology clinicians
Q97566161Impact of COVID-19 pandemic on treatment patterns in metastatic clear cell renal cell carcinoma
Q57170878Impact of abiraterone acetate plus prednisone or enzalutamide on fatigue and cognition in patients with metastatic castration-resistant prostate cancer: initial results from the observational AQUARiUS study
Q123134240Impact of age and gender on the efficacy and safety of upfront therapy with panitumumab plus FOLFOX followed by panitumumab-based maintenance: a pre-specified subgroup analysis of the Valentino study
Q55208892Impact of clinical response to neoadjuvant endocrine therapy on patient outcomes: a follow-up study of JFMC34-0601 multicentre prospective neoadjuvant endocrine trial.
Q102053467Impact of clinical versus radiographic progression on clinical outcomes in metastatic castration-resistant prostate cancer
Q54628350Impact of intervention aimed at improving the integration of oncology units and local palliative care services: results of the multicentre prospective sequential MIRTO study.
Q89700294Impact of prior cancer history on the overall survival of younger patients with lung cancer
Q99727027Impact of solid cancer on in-hospital mortality overall and among different subgroups of patients with COVID-19: a nationwide, population-based analysis
Q96639578Impact of the COVID-19 outbreak on cancer patient flow and management: experience from a large university hospital in Spain
Q94552581Impact of tumour growth rate during preceding treatment on tumour response to regorafenib or trifluridine/tipiracil in refractory metastatic colorectal cancer
Q91047163Implementation of lung cancer screening in Europe: challenges and potential solutions: summary of a multidisciplinary roundtable discussion
Q64229216Implementing TMB measurement in clinical practice: considerations on assay requirements
Q102388054Implementing clinical practice guidelines: time to assess it
Q55449354Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate.
Q64994221Importance of genetic screens in precision oncology.
Q97903480Improved efficacy of taxanes and ramucirumab combination chemotherapy after exposure to anti-PD-1 therapy in advanced gastric cancer
Q55035714In the literature: April 2017.
Q55021644In the literature: April 2018.
Q92972168In the literature: April 2019
Q92128346In the literature: April 2020
Q92684935In the literature: August 2018
Q58780159In the literature: August 2018
Q98574907In the literature: August 2020
Q125128035In the literature: August 2021
Q60049457In the literature: December 2018
Q92771636In the literature: December 2019
Q104745958In the literature: December 2020
Q55083430In the literature: February 2017.
Q55028337In the literature: February 2018.
Q64280651In the literature: February 2019
Q89807865In the literature: February 2020
Q55242537In the literature: June 2018.
Q91812600In the literature: June 2019
Q97529733In the literature: June 2020
Q54877466In the literature: March 2016.
Q55116636In the literature: May 2016.
Q54023284In the literature: October 2016.
Q59138833In the literature: October 2018
Q91673718In the literature: October 2019
Q100512002In the literature: October 2020
Q55254683Incidence of cetuximab-related infusion reaction in head and neck cancer patients: may we predict it?
Q99616292Increasing completion of asparaginase treatment in childhood acute lymphoblastic leukaemia (ALL): summary of an expert panel discussion
Q94472860Indications regarding the management of interventional clinical trials with drugs during the current COVID-19 emergency in Italy
Q64905201Indicators of integration at ESMO Designated Centres of Integrated Oncology and Palliative Care.
Q54974210Indispensable benefit of independent investigator-driven research in a changing clinical trial landscape.
Q53990140Indolent peritoneal mesothelioma: PI3K-mTOR inhibitors as a novel therapeutic strategy.
Q99349386Induction of natural killer antibody-dependent cell cytotoxicity and of clinical activity of cetuximab plus avelumab in non-small cell lung cancer
Q96300938Infection rate and clinical management of cancer patients during the COVID-19 pandemic: experience from a tertiary care hospital in northern Italy
Q91815526Infection risk with PI3K-AKT-mTOR pathway inhibitors and immune checkpoint inhibitors in patients with advanced solid tumours in phase I clinical trials
Q100944714Influenza in hospitalised patients with malignancy: a propensity score matching analysis
Q55068559Initial experience with the bispecific anti-CEA anti-CD3 antibody and its expected impact on future treatment for patients with colorectal cancer.
Q91368844Innovative oncology products: time to revisit the strategy development?
Q28066709Integrating next-generation sequencing into clinical oncology: strategies, promises and pitfalls
Q112641619Integrative molecular analysis of combined small-cell lung carcinomas identifies major subtypes with different therapeutic opportunities
Q54703477Inter-institutional heterogeneity in outcomes of chemotherapy for metastatic gastric cancer: correlative study in the JCOG9912 phase III trial.
Q92684916Interim analysis of a real-world precision medicine platform for molecular profiling of metastatic or advanced cancers: MONDTI
Q54917990International survey of androgen deprivation therapy (ADT) for non-metastatic prostate cancer in 19 countries.
Q64280661Interprofessional spiritual care in oncology: a literature review
Q28067650Interventions to improve care coordination between primary healthcare and oncology care providers: a systematic review
Q92241738Introducing a new ESMO Open article series: how I treat side effects of immunotherapy
Q58694056Introducing the Metastatic Breast Cancer Project: a novel patient-partnered initiative to accelerate understanding of MBC
Q55070614Is CBOP/BEP an alternative to BEP for patients with poor prognosis metastatic germ cell tumours?
Q58790699Is smoking history the truly best biomarker for immune checkpoint inhibitor treatment in advanced non-small cell lung cancer?
Q28069764KRAS-driven lung adenocarcinoma: combined DDR1/Notch inhibition as an effective therapy
Q55083559Key differences between 13 KRAS mutation detection technologies and their relevance for clinical practice.
Q64056304Knowledge and use of biosimilars in oncology: a survey by the European Society for Medical Oncology
Q104745972Knowledge, attitudes and practices related to the COVID-19 outbreak among Romanian adults with cancer: a cross-sectional national survey
Q95934747LKB1 mutations are not associated with the efficacy of first-line and second-line chemotherapy in patients with advanced non-small-cell lung cancer (NSCLC): a post hoc analysis of the TAILOR trial
Q54918960Lactobacillus brevis CD2 lozenges prevent oral mucositis in patients undergoing high dose chemotherapy followed by haematopoietic stem cell transplantation.
Q101241760Late decisions about treatment limitation in patients with cancer: empirical analysis of end-of-life practices in a haematology and oncology unit at a German university hospital
Q126003464Learning lessons from the COVID-19 pandemic for real-world evidence research in oncology—shared perspectives from international consortia
Q90437273Lessons learned at SABCS 2019 and to-dos from immunotherapy in breast cancer
Q99204235Lessons learnt from scoring adjuvant colon cancer trials and meta-analyses using the ESMO-Magnitude of Clinical Benefit Scale V.1.1.
Q54856582Life-threatening colitis and complete response with ipilimumab in a patient with metastatic BRAF-mutant melanoma and rheumatoid arthritis.
Q90291965Liquid biopsy assessment of synchronous malignancies: a case report and review of the literature
Q55340002Liquid biopsy for HER2-positive breast cancer brain metastasis: the role of the cerebrospinal fluid.
Q113874540Long-term benefit of lurbinectedin as palliative chemotherapy in progressive malignant pleural mesothelioma (MPM): final efficacy and translational data of the SAKK 17/16 study
Q104745955Longitudinal characterisation of haematological and biochemical parameters in cancer patients prior to and during COVID-19 reveals features associated with outcome
Q57214474Low-dose nivolumab can be effective in non-small cell lung cancer: alternative option for financial toxicity
Q102074643Lower risk of severe checkpoint inhibitor toxicity in more advanced disease
Q102210208Lung cancer symptoms at diagnosis: results of a nationwide registry study
Q118176618Lymphovascular invasion has a significant prognostic impact in patients with early breast cancer, results from a large, national, multicenter, retrospective cohort study
Q102388052Machine learning: an approach to preoperatively predict PD-1/PD-L1 expression and outcome in intrahepatic cholangiocarcinoma using MRI biomarkers
Q58801445Macrophage repolarisation therapy in colorectal cancer
Q113874536Maintenance therapy with a poly(ADP-ribose) polymerase inhibitor in patients with newly diagnosed advanced epithelial ovarian cancer: individual patient data and trial-level meta-analysis
Q54775458Male breast cancer: finding the way in this uncommon path.
Q104281204Management of breathlessness in patients with cancer: ESMO Clinical Practice Guidelines
Q55032398Management of metastatic colorectal cancer patients: guidelines of the Italian Medical Oncology Association (AIOM).
Q102151751Management of orphan symptoms: ESMO Clinical Practice Guidelines for diagnosis and treatment†
Q103825784Management of patients with early-stage colon cancer: guidelines of the Italian Medical Oncology Association
Q55019941Management of patients with end-stage renal disease undergoing chemotherapy: recommendations of the Associazione Italiana di Oncologia Medica (AIOM) and the Società Italiana di Nefrologia (SIN).
Q54979977Management of recurrent or metastatic thyroid cancer.
Q60054414Management of young women with early breast cancer
Q100512000Managing toxicities with asparaginase-based therapies in adult ALL: summary of an ESMO Open-Cancer Horizons roundtable discussion
Q64933332Maximising clinical benefit with adequate patient management beyond the second line in mCRC.
Q55060215Mechanisms of action and rationale for the use of checkpoint inhibitors in cancer.
Q28077415Mechanisms of resistance to EGFR-targeted drugs: lung cancer
Q102378014Mentoring as an opportunity to improve research and cancer care in Latin America (AAZPIRE project)
Q54967387Metal drugs become targeted.
Q96124442Metastatic breast cancer and pseudocirrhosis: an unknown clinical entity
Q55111318Methodological issues in the choice among different drugs approved for the same therapeutic indication: a position paper by the Italian Association of Medical Oncology (AIOM).
Q101120497MiR-100 is a predictor of endocrine responsiveness and prognosis in patients with operable luminal breast cancer
Q64094662Modulation of peripheral blood immune cells by early use of steroids and its association with clinical outcomes in patients with metastatic non-small cell lung cancer treated with immune checkpoint inhibitors
Q102335571Molecular characteristics of BRCA1/2 and PALB2 mutations in pancreatic ductal adenocarcinoma
Q91368839Molecular findings reveal possible resistance mechanisms in a patient with ALK-rearranged lung cancer: a case report and literature review
Q28076360Molecular pathology of cancer: how to communicate with disease
Q96639277Molecular profile of BRCA-mutated biliary tract cancers
Q104745974Molecular profiling of Asian patients with advanced melanoma receiving check-point inhibitor treatment
Q99571852Molecular target: pan-AKT in gastric cancer
Q92972096Moving cancer care closer to home: a single-centre experience of home chemotherapy administration for patients with myelodysplastic syndrome
Q54620120Multicentre phase II study of nivolumab in Japanese patients with advanced or recurrent non-squamous non-small cell lung cancer.
Q57652296Multidisciplinary molecular tumour board: a tool to improve clinical practice and selection accrual for clinical trials in patients with cancer
Q114180880Multimodal survival prediction in advanced pancreatic cancer using machine learning
Q54942556Multiple primary tumours: challenges and approaches, a review.
Q98574901Mycobacterial infections due to PD-1 and PD-L1 checkpoint inhibitors
Q28066821NTRK gene fusions as novel targets of cancer therapy across multiple tumour types
Q55077233NanoString expression profiling identifies candidate biomarkers of RAD001 response in metastatic gastric cancer.
Q102058743Natural history and prognostic factors for localised small bowel adenocarcinoma
Q90167445Neoadjuvant radiotherapy in the approach of locally advanced breast cancer
Q64914318Neoadjuvant treatment for intermediate/high-risk HER2-positive and triple-negative breast cancers: no longer an 'option' but an ethical obligation.
Q102335568Neoadjuvant treatment for locally advanced unresectable and borderline resectable pancreatic cancer: oncological outcomes at a single academic centre
Q55265980Neoadjuvant treatment: the future of patients with breast cancer.
Q55068724Neutrophil to lymphocyte ratio (NLR) for prediction of distant metastasis-free survival (DMFS) in early breast cancer: a propensity score-matched analysis.
Q53981393Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio before chemotherapy as potential prognostic factors in patients with newly diagnosed epithelial ovarian cancer.
Q99550699New biomarkers for checkpoint inhibitor therapy
Q55022021New data: new options for front-line therapy in NSCLC?
Q91642011New emerging targets in cancer immunotherapy beyond CTLA-4, PD-1 and PD-L1: Introducing an "ESMO Open - Cancer Horizons" Series
Q96950741New emerging targets in cancer immunotherapy: CD137/4-1BB costimulatory axis
Q90167531New emerging targets in cancer immunotherapy: CD27 (TNFRSF7)
Q91642022New emerging targets in cancer immunotherapy: the role of Cluster of Differentiation 40 (CD40/TNFR5)
Q98575117New emerging targets in cancer immunotherapy: the role of GITR
Q64994684New emerging targets in cancer immunotherapy: the role of LAG3.
Q91642003New emerging targets in cancer immunotherapy: the role of TIM3
Q96589493New emerging targets in cancer immunotherapy: the role of VISTA
Q91737349New emerging targets in cancer immunotherapy: the role of neoantigens
Q54185643New horizon in breast cancer therapy: highlights from the European Society for Medical Oncology.
Q54476966New molecular and immunotherapeutic approaches in biliary cancer.
Q94552595New pathways in immune stimulation: targeting OX40
Q55607045New therapeutic targets in the inflammatory microenvironment.
Q54990172New treatment options for metastatic renal cell carcinoma.
Q89700291News on the horizon in glioblastoma therapy
Q54963459Nivolumab for NSCLC in Japanese patients: similar benefits, but beware of pneumonitis.
Q103025953Nivolumab plus ipilimumab versus sunitinib for first-line treatment of advanced renal cell carcinoma: extended 4-year follow-up of the phase III CheckMate 214 trial
Q97635556Nivolumab treatment of elderly Japanese patients with non-small cell lung cancer: subanalysis of a real-world retrospective observational study (CA209-9CR)
Q55209741Nivolumab-induced hypothyroidism and selective pituitary insufficiency in a patient with lung adenocarcinoma: a case report and review of the literature.
Q54963997Novel active agents in patients with advanced NSCLC without driver mutations who have progressed after first-line chemotherapy.
Q54863313Novel prognostic prediction models for patients with stage IV colorectal cancer after concurrent curative resection.
Q55305291Nutrition in patients with cancer: a new area for medical oncologists? A practising oncologist's interdisciplinary position paper.
Q89807850Olanzapine combined with 5-hydroxytryptamine type 3 receptor antagonist (5-HT3 RA) plus dexamethasone for prevention and treatment of chemotherapy-induced nausea and vomiting in high and moderate emetogenic chemotherapy: a systematic review and meta
Q112578636Olaparib in combination with pegylated liposomal doxorubicin for platinum-resistant ovarian cancer regardless of BRCA status: a GEICO phase II trial (ROLANDO study)
Q92006270Olaratumab administered in two cases of phyllodes tumour of the breast: end of the beginning?
Q98732997Oncological care organisation during COVID-19 outbreak
Q55237909One year of ESMO Open: Cancer Horizons-where are we going from here?
Q55342871Optimising the use of cetuximab in the continuum of care for patients with metastatic colorectal cancer.
Q99593447Optimising triage procedures for patients with cancer needing active anticancer treatment in the COVID-19 era
Q55438459Oral rehydration solution (OS-1) as a substitute of intravenous hydration after cisplatin administration in patients with lung cancer: a prospective multicenter trial.
Q103025958Outcomes of patients with metastatic gastrointestinal stromal tumors (GIST) treated with multi-kinase inhibitors other than imatinib as first-line treatment
Q101563766PD-1 protein and gene expression as prognostic factors in early breast cancer
Q90861326PHOTOSTENT-02: porfimer sodium photodynamic therapy plus stenting versus stenting alone in patients with locally advanced or metastatic biliary tract cancer
Q98574873PIK3CA mutation inhibition in hormone receptor-positive breast cancer: time has come
Q129589496PO-001 Environmental toxins can transform mammary cells and induce chemo-resistance in breast cancer via multiple mechanisms
Q129589399PO-001 Therapeutic inhibition of trefoil factor 3(TFF3) decrease oncogenic behaviour in non-small cell lung cancer (NSCLC)
Q129588557PO-002 Angiotensin II-induced hypertension increases the mutation frequency in the rat kidney
Q129587260PO-002 Single siRNA mediated post transcriptional and transcriptional gene silencing of HPV18 oncogenes
Q129586651PO-003 Metformin restores nickel-reduced glutathione S-transferase Mu2 expression by promoter methylated alteration
Q129587885PO-004 Antibodies targeting the heparin-binding domain of fibroblast growth factor receptor 1 for cancer therapy
Q129586904PO-004 The clinical relevance and functional role of ACADM in hepatocellular carcinoma
Q129586799PO-005 Prevention strategies for intestinal cancer development in lynch syndrome
Q129586702PO-006 Generation of recombinant antibody variable fragments in baculovirus expression system targeted against epidermal growth factor receptor mutant expressing glioblastoma
Q129588206PO-006 The MAPK/c-Myc axis in CRC: new pathogenic mechanisms and therapeutic approaches
Q129587190PO-007 Investigating the hyperactivation of ERK5 signalling in skin cancer
Q129587875PO-008 Accelerated DNA methylation in gastric mucosa adjacent to cancer after HELICOBACTER PYLORI eradication
Q129587161PO-008 Anti-tumour properties of novel multikinase inhibitors in sarcomas: synergistic combination with doxorubicin
Q129586693PO-009 A novel integrin alpha 5 binding peptide potentiates effects of chemotherapy in pancreatic cancer
Q129585880PO-009 Investigating the putative cleavage site of C-terminally truncated MRE11 using mass spectrometry and its function on DNA damage repair
Q129588930PO-010 Dual chemotherapy and photodynamic therapy: a synergistic strategy to improve cancer treatment
Q129589470PO-010 PRMT1 methylates and regulates the deubiquitinating enzyme USP11 modulating the DNA damage response in breast cancer cells
Q129587431PO-011 Dihydroartemisinin inhibits TCTP-dependent metastasis in gallbladder cancer
Q129588047PO-011 Impact of compartment-specific changes in NAD biosynthesis on diethylnitrosamine-induced liver cancer
Q129588747PO-012 Ferulic acid increases ABT-888 sensitivity in breast cancer cells
Q129587354PO-012 Pre-clinical insight into how platelet count affects the activity of HDACi resminostat in combination with the multi-kinase inhibitor sorafenib in HCC
Q129586013PO-013 A novel peptidomimetic targeting NRP1 increases radiosensitivity of medulloblastoma stem cells
Q129588308PO-013 BRCA1 and BRCA2 next generation sequencing in high-grade serous ovarian cancer
Q129587253PO-014 Dianhydrogalactitol (vaL-083) reduces glioblastoma tumour progression in vivo, upon bevacizumab-induced hypoxia
Q129586154PO-014 Targeting PARP1 in XRCC1 deficient sporadic invasive breast cancer or pre-invasive ductal carcinoma in situ for synthetic lethality and chemoprevention
Q129586579PO-015 DNA damage response reporters in breast cancer
Q129589369PO-015 Potentiating anti-neoplastic effect of cisplatin by a protein arginine methyltransferase 5 selective inhibitor in lung adenocarcinoma cells
Q129586040PO-016 Inhibition of cell proliferation by anti-epidermal growth factor receptor (EGFR) aptamer conjugated chitosan/siRNA nanoparticles
Q129588547PO-016 The role of autophagy-related protein 9B in liver carcinogenesis
Q129588507PO-017 Androgen deprivation and oxidative phosporylation inhibition pose synergistic antitumor effects in subsets of prostate tumours in vitro
Q129586555PO-017 Is RECQL4 a novel player in glioblastoma pathogenesis?
Q129586704PO-018 Acquired DNA damage in adolescent obesity – a promoter and predictor of cancer?
Q129587383PO-018 Immunogenic potential of cold atmospheric plasma for the treatment of pancreatic cancer
Q129588150PO-019 PTPN11 is a therapeutic target in KRAS mutant lung cancer
Q129587310PO-019 Phosphoproteomics to characterise DNA damage response in mouse mammary tumours of different PARP inhibitor susceptibility
Q129587999PO-020 Discrepancy in efficacy of disulfiram between NUP98-PHF23 fusion acute myelogenous leukaemia cell line and in vivo mouse model: sharing normal hematopoietic stem cells niche
Q129588497PO-020 Functional characterisation of variant of unknown significate in familial breast cancer
Q129588640PO-021 Inhibition of MK2 stabilises wild-type P53 and improves temozolomide efficacy in glioblastoma
Q129586711PO-022 Benzamide class of HDACi differentially enhance sodium iodide symporter expression in breast cancer
Q129589273PO-022 FISH probes for the detection of high-risk HPV nucleic acid in infected host cells
Q129585837PO-023 A multi-step framework to analyse high-throughput drug combination screens
Q129589108PO-024 Perioperative blockade of stress-inflammatory responses improves biomarkers of metastasis in excised tumours and blood samples: phase ii clinical trials in colorectal and breast cancer patients
Q129589367PO-024 SETD1A regulates cell proliferation by modulating miR205 in triple negative breast cancers (TNBCS)
Q129587565PO-025 Antiproliferative effects of rosemary (rosmarinus officinalis, L.) extract in colon cancer cells lines
Q129589110PO-025 Effects of entinostat on cell viability and cell cycle in oral cancer cell lines
Q129588823PO-026 72 Rosemary (rosmarinus officinalis, L.) extract inhibits cell proliferation and migration in colon cancer cells lines
Q129587146PO-026 Metformin inhibits the NGF-induced increase c-MYC and VEGF levels in ovarian cancer cells
Q129588800PO-027 Potential use of BH3 mimetics in the treatment of head and neck cancer
Q129586019PO-028 Effective targeting of NAD+biosynthesis in patient-derived xenograft models of high-risk paediatric acute lymphoblastic leukaemia
Q129589410PO-028 Effectiveness and molecular basis of CDK4/6 inhibition in combination with taxanes in pancreatic cancer
Q129587951PO-029 Angiotensin-(1–7) promotes migration of renal cell carcinomacells with no effect on cell proliferation
Q129587671PO-029 Supercritical carbon dioxide extract of mucuna pruriens inhibits brain cancer tumour growth in rats
Q129586870PO-030 Cold atmospheric plasma treatment in breast cancer
Q129585795PO-030 Functional analysis of mastl mutations in cancer
Q129587434PO-031 NAA induces antitumoral effects in BXPC3 pancreatic cancer cell line
Q129585937PO-031 Sensitising P53 mutant HNSCC to oncolytic reovirus (RT3D) by targeting the unfolded protein response
Q129586248PO-032 Displacement of hexokinase 2 from mitochondria induces mitochondrial Ca2 +overload and caspase-independent cell death in cancer cells
Q129586550PO-032 The knock-down of ferritin heavy subunit induces xenobiotic-resistance in K562 cells through the activation of NF-kB pathway
Q129589253PO-033 Anticancer activity of natural high mobility group BOX1 inhibitors in colorectal cancer cells
Q129586246PO-033 Identification and functional evaluation of monoclonal antibodies specifically targeting human carbonic anhydrase IX
Q129588552PO-034 Inhibition of lung carcinoma growth and pulmonary metastasis with DIMATE as single agent and in combination with cisplatin
Q129588692PO-035 LKB1 deficiency renders non-small-cell lung cancer cells sensitive to ERK inhibitor
Q129587317PO-036 Traditional chinese medicine Ze-Qi-TANG formula induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in lung cancer
Q129589376PO-037 Role of MARCH8 in esophageal squamous cell carcinoma
Q129587157PO-037 Targeting mutant p53 with COTI-2: a new approach for the treatment of patients with triple-negative breast cancer?
Q129587151PO-038 PKC isoforms distinctively modulate telomerase expression and AFP secretion in hepatocellular carcinoma
Q129586632PO-039 Examination of the anti-tumour and neuropathic side effect responses of first generation and second generation proteasome inhibitors
Q129585887PO-039 Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells
Q129587209PO-040 Characterisation of CDK12 knocked out ovarian cancer cell lines
Q129588100PO-040 Development of a tunable form of interferon alpha for in vivo cancer gene therapy
Q129586563PO-041 Cold atmospheric plasma: a potentially selective and non-inflammatory anti-cancer therapy
Q129587924PO-041 TNF pathway in metastatic colorectal cancer according to RAS status and implication of potassium channels
Q129587482PO-042 Targeting hypoxic pancreatic cancer cells with glucose conjugated lactate dehydrogenase inhibitor NHI-Glc-2
Q129588707PO-043 Development of two novel monoclonal antibodies against overexpressed antigens on pancreatic cancer cells for use in diagnosis and therapy
Q129586233PO-043 Targeting the thiol oxidoreductases ERp57 and PDI hits cancer cells on multiple fronts: proliferation, radioresistance and ER stress response (UPR)
Q129589109PO-044 Development of flow cytometric assays for CAR T cell manufacturing and patient immunomonitoring
Q129589457PO-044 Possible involvement of G2/M block defects in cell sensitivity towards ATR inhibitors
Q129588192PO-045 Evaluating liquid biopsies for methylomic profiling of prostate cancer
Q111491249PO-045 Marine invertebrate extracts inhibit proliferation, migration and invasion in colon cancer cell models
Q129586815PO-046 Dual inhibition of JAK and Src: a novel and promising therapeutic combination for pancreatic cancer
Q129586037PO-046 The antiproliferative activity and cell death effects of four marine invertebrate extracts in colon cancer cells
Q129587829PO-047 Etarget: a digital science solution to integrate clinical and genomic data for the manchester molecular tumour board (MTB)
Q129587351PO-047 SOX6 is a direct EWSR1-FLI1 target gene contributing to tumour growth of ewing sarcoma
Q129586153PO-048 Therapeutic relevance of the cell cycle protein BORA in cancer
Q129586168PO-048 Therapy response testing using a 3d perfused microfluidic platform
Q129587188PO-049 EGFR blockade induces a paneth cell-like phenotype with rewired signalling dependencies in CRC tumoursat maximal response
Q129588616PO-049 Quantitative proteomics unveils key mitotic regulators involved in the transition to androgen independent prostate cancer
Q129587289PO-050 A molecularly annotated platform of pdx-derived cell lines mirrors the genomic landscape of colorectal cancer
Q129585902PO-050 Long noncoding RNA, ANRIL positively regulates cell proliferation in a P15/P16-dependent and -independent manners
Q129588045PO-051 Familial risks and mortality in second primary cancers of ovarian cancer patients
Q129585743PO-051 GNL1 regulates cell proliferation by associating with RPS20
Q129589219PO-052 Selenium status and survival from colorectal cancer in the european prospective investigation of cancer and nutrition
Q129589374PO-052 Significance of miR-100–5 P/99A-5P and MIR-125B-5P under-expression in malignant germ cell tumours
Q129586739PO-053 The phospholipase DDHD1 as a new target in colorectal cancer therapy
Q129585723PO-054 Common genetic variants at the breast cancer risk region 2Q35 map to putative IGFbp5 enhancers
Q129588545PO-054 Traditional chinese medicine Ze-Qi-tang formula induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in lung cancer
Q129587969PO-055 STAT6 SIRNA reduces proliferation of and induces apoptosis in the human colon adenocarcinoma cell line HT-29
Q129589299PO-056 The epigenetic drugs zebularine and trichostatin a enhanced the TRAIL-induced apoptosis in the aggressive triple negative breast cancer
Q129588828PO-056 The impact of WNT1-inducible signalling pathway protein 1 polymorphism on hepatocellular carcinoma susceptibility
Q129589214PO-057 Genetic interaction and pathway based discovery of key regulators in multiple myeloma
Q129587258PO-057 Genistein, a major isoflavone component, suppresses Src-induced proliferative activity by arresting cell cycle at G2/M through increasing the P53 and P21 levels
Q129586225PO-058 Unravelling the protective role of androgens/androgen receptorin breast cancer: when BAD goes good
Q129587311PO-059 Cancer-predisposing variants in alternatively spliced TP53 exons
Q129588009PO-060 Association between RS10993994 polymorphism in MSMB gene with early-onset prostate cancer in mexican men
Q129587309PO-060 ErbB2/Her2-dependent downregulation of a transcription factor IRF6 in breast cancer cells is required for their three-dimensional growth
Q129587303PO-061 BCL-2 family of proteins, BCL-XL and MCL-1, regulate apoptosis and cancer cell survival by different mechanisms
Q129588068PO-061 Exploring heritable predisposition to paediatric rhabdomyosarcomas
Q129586606PO-062 BAX and BAK interaction with the mitochondrial permeability transition pore (MPTP) is required for taxol-mediated apoptosis
Q129585860PO-062 Circulating tumour cells in patients with non-small cell lung cancer exhibit notable heterogeneity
Q129586638PO-063 Pre-diagnostic unconjugated bilirubin levels and colorectal cancer risk in the european prospective investigation into cancer and nutrition (EPIC)
Q129585930PO-063 Triterpenoids isolated from natural product regulates TNF(tumour necrosis factor)-mediated RIP(receptor-interacting serine/threonine-protein kinase)1-dependent apoptosis
Q129588615PO-064 Early birth order and increased risk of lymphoid cancers and allergies in lymphoid cancer families
Q129588523PO-064 Tubulin-binding anti-cancer polysulfides induce cell death via mitotic arrest and autophagic interference in colon cancer
Q129587940PO-065 Assessment of prognostic models for stage II/III colon cancer: a hospital-based prospective cohort study
Q129588163PO-066 Knockdown of cadherin 17 inactivates WNT signalling pathway and induces apoptosis in colorectal cancer cells
Q129589239PO-066 Risk of malignant neoplasms of blood and lymphatic system of liquidators of the chernobyl accident in the republic of belarus
Q129588465PO-067 Autophagy modulates response to cisplatin in thyroid cancer cells
Q129589380PO-067 Thyroid cancer incidence in belarusian residents exposed to chernobyl fallout
Q129587435PO-068 Atlas of causal risk factors for epithelial ovarian cancer risk: a mendelian randomization analysis in up to 66 450 women
Q129586576PO-068 Determining how distinct microenvironments alter BCL-2 family dependence in T-cell acute lymphoblastic leukaemia
Q129589223PO-069 Clinical and histological risk factors for subsequent in situ lesions after a primary diagnosis of ductal carcinoma in situ
Q129588128PO-070 Evaluation the cytotoxic effect of carmofur on MCF-7 human breast cancer cell line
Q129589173PO-070 Identification of risk factors for subsequent invasive breast cancer after primary DCIS by transcriptomic profiling
Q129585736PO-071 Risk factors associated with mortality from kidney diseases in patients diagnosed with multiple myeloma: a population-based analysis
Q129587929PO-071 Silencing of circRNA004582 sensitises gastric cancer cells to APATINIB via modulating autophagy by targeting miR-3657 and ATG7
Q129589054PO-072 Adjusting for systematic technical biases in risk assessment of gene signatures in genomic cohorts
Q129587155PO-073 Dual targeting of proliferative pathways in BRAF-mutant melanoma cells by PYRIDINYL IMIDAZOLE compounds
Q129585746PO-073 Small non-coding RNA in serum from testicular germ cell tumour patientsidentified by machine learning
Q129589318PO-074 Metformin-induced apoptosis facilitates degradation of the C-FLIPL protein through a caspase-dependent pathway in human renal cell carcinoma A498 cells
Q129587380PO-075 Methanol fraction of calliandra portoricensis induces apoptosis and growth arrest in prostatic tumour cell lines
Q129587664PO-075 Study of the biomarker potential of long non-coding RNAs HULC in breast cancer
Q129587101PO-076 HMNQ induces apoptosis and autophagy dependent on reactive oxygen species through activation of JNK signalling pathway
Q129585906PO-076 Molecular analysis of BRCA-negative breast and/or ovarian cancer families by multigene panel testing
Q129585814PO-077 Identification of DHX30 as an inhibitor of the translation of pro-apoptotic mRNAS after P53 activation by nutlin
Q129588504PO-077 Tobacco use and cancer awareness among irula tribes, nilgiri hills, tamilnadu, india
Q129588007PO-079 Dysregulation of miR-196B in head and neck cancers leads to pleiotropic effects in the tumour cells and CAFs
Q129588413PO-079 Effect of a escin nano-formulation on human lung adenocarcinoma cells
Q129588002PO-080 Prevalence of human papilloma virus and its phylogenetic analysis in patients with head and neck squamous cell carcinoma in pakistan
Q129588824PO-080 V-ATPase G1 expression in human glioma stem cells correlates with ERK activation
Q129585769PO-081 Hypermethylation responses to inorganic arsenic exposure may increase the risk of liver cancer occurrence
Q129587087PO-081 Notch signalling pathway plays a crucial role in maintaining the cancer stem cell population in lung and colorectal cancer
Q129586206PO-082 BMP4-induced differentiation does not enhance chemosensitivity of glioma stem-like cells to temozolomide
Q129589240PO-082 Salivary extracellular vesicles from oral cancer patients: exclusive signature of the infrared spectrum
Q129586677PO-083 Suppressing the accumulation of cancer stem cells (CSC) using HDAC inhibitor reverses HNSCC chemoresistance by targeting NFKB signalling
Q129587923PO-083 The role of the humoral immune system in pancreatic cancer
Q129588498PO-084 Ascorbic acid selectively targets glucose metabolism of osteosarcoma stem cells
Q129585754PO-084 Familial risk of colorectal cancer in half-siblings similar to that in siblings
Q129589290PO-085 MiR-424(322)/503 regulates Wnt/b-catenin pathway and resistance to treatment in breast cancer
Q129586837PO-085 Mutational profiling can identify laryngeal dysplasia at risk of progression to invasive carcinoma
Q129586714PO-086 BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous cell carcinoma
Q129588745PO-087 Oxidative stress as a selective anticancer agent: preclinical evaluation of a targeted combination strategy for mutant P53 non-small cell lung cancer
Q129588599PO-087 The WCRF/AICR third expert report on diet, nutrition, physical activity and cancer: updated recommendations
Q129588474PO-088 A modified electrochemical biosensor for sensitive detection of human chorionic gonadotropin (hCG) biomarker
Q129586727PO-089 135 Targeting treatment resistance in breast cancer subtypes via LMTK3 inhibition
Q129588204PO-089 The evidence on early growth and development and the risk of cancer by the WCRF/AICR continuous update project
Q129588770PO-090 Expression of the cocaine- and amphetamine-regulated transcript (CART) recruits SWI/SNF chromatin remodelling complexes to the oestrogen receptor
Q129589398PO-091 Droplet digital PCR based detection of aberrantly methylated genes in bile identifies cholangiocarcinoma in patients with primary sclerosing cholangitis
Q129588076PO-091 Induction of anti-Fas regulates PUMA and MYC: P53-dependent apoptosis pathway in hepatocellular carcinoma cells
Q129586856PO-092 Inhibition of the mTORC1-pathway can feedback-activate H-RAS or K-RAS
Q129587590PO-092 Sensitivity and specificity accurate of sniffing dogs to detect lung cancer
Q129587570PO-093 A hep-2 cell model as tool for analysing DNA double strand breaks in cancer patients
Q129588201PO-093 Lipocalin 2 suppress metastases of oral cancer through miRNA-29A-regulated dipeptidyl peptidase-4
Q129587147PO-094 A novel prognostic significance of combination of preoperative systemic immune-inflammation index and monocyte-lymphocyte ratio in upper tract urothelial carcinoma
Q129586628PO-094 Persistent Myc activity prevents resolution of liver injury
Q129587563PO-095 ICOS: a crucial immunomodulator for development of immunotherapy
Q129586810PO-095 PIM kinases in the regulation of prostate cancer cell motility
Q129586512PO-096 Defining the role of Myc in the pancreatic cancer super enhancer network
Q129589334PO-096 Natural variation in serum small non-coding RNAs – potential biomarkers of cancer
Q129588934PO-097 Integration of data across toxicity endpoints to explore new ways for carcinogenicity safety assessment of chemicals
Q129586720PO-098 Peroxiredoxin II promotes hepatic tumorigenesis through cooperation with RAS/forkhead box M1 signalling pathway
Q129589068PO-098 Prevalence of head and neck cancers, and tobacco use among malayali tribes, yelagiri hills, tamil nadu, india
Q129586797PO-099 Age differences in coping strategies among patients with colorectal cancer
Q129586763PO-099 Targeting the mitogen activated protein kinase ERK5 in human melanoma
Q129587186PO-100 Targeting YAP and TAZ to treat hippo pathway mutant malignant mesotheliomas
Q129586718PO-101 P53 core domain activity at low PH
Q129589364PO-101 Relation between PSA level, its dynamics and performance of 18F-choline PET-CT in recurrent prostate cancer
Q129586662PO-102 Pre-diagnostic serum calcium concentrations and risk of colorectal cancer development in a prospective european cohort
Q129588854PO-102 Understanding the role of the tumour suppressor, FLCN, in renal tumorigenesis
Q129589055PO-103 Can we eat to prevent colorectal cancer?
Q129589469PO-103 Regulation of prostate cancer cell growth and signalling by exercise
Q129589084PO-104 Role of the oncosuppressor CTCF in the erythroid cell differentiation and regulation of erythroid genes
Q129585982PO-105 CDH3/P-cadherin as a novel biomarker in glioblastoma: functional and prognostic insights
Q129587299PO-106 Downregulation of MYPT increases tumorigenesis and resistance to platin drugs in ovarian cancer
Q129588084PO-106 Unique and overlapping role of HIF proteins in radiation response and tumour cell metabolism
Q129588626PO-107 A potential role for DELTA40P53 in the regulation of breast cancer stem cells
Q129586601PO-107 Notch signalling pathway is required for proliferation, repair and differentiation of primary human lung stem cells upon irradiation
Q129586009PO-108 FKBP10 is an oncofetal protein that supports lung cancer growth by promoting protein translation elongation
Q129586716PO-108 Nonstandard hypofraction radiotherapy in neoadjuvant chemo-radiation therapy in treatment of locally advanced rectal cancer
Q129588560PO-109 Integral membrane protein 2A expression leads to enhanced anti-cancer effects and chemosensitivity in epithelial ovarian cancer
Q129587305PO-109 Particle therapy reduces weight loss and toxicities among patients with head and neck cancer
Q129588541PO-110 AKT expression is associated with poor clinical outcome in ovarian cancer
Q129587458PO-110 Targeted alpha-therapy for gastric cancer metastasized to liver in mice
Q129589310PO-111 Capicua suppresses hepatocellular carcinoma progression by controlling ETV4-MMP1 axis
Q129589156PO-111 Non-contact electric fields inhibit the growth of breast cancer cells in animal models and induce local immune reaction
Q129588679PO-112 The role of transcribed ultraconserved regions Uc160 and Uc346 in colorectal cancer progression
Q129586081PO-112 The senescence associated secretory phenotype (SASP)-factor CcL2 fosters vascular dysfunction and endothelial cell loss in radiation-induced lung disease
Q129587140PO-113 Investigation of the role of IRF4 in melanoma cells
Q129588631PO-113 PARP-1 depletion in combination with either high or low LET reduces the metastatic potential in cultured human cells by suppression of its MMP activity
Q129587266PO-114 Histone deacetylase 6 regulates NOTCH3 endosomal trafficking and degradation in T-cell acute lymphoblastic leukaemia cells
Q129589325PO-114 Overexpression of miR-205–3 p increases sensitivity to low-dose ionising radiation in DLD-1 cells
Q129588803PO-115 HER2-amplified tumours overcome the requirement for HER3
Q129586094PO-115 Radiation resistance mechanisms of breast cancer cells
Q129587922PO-116 Increase in prothymosin alpha expression with histological aggressiveness of glioma
Q129589189PO-116 Indium-111 afterloading of preformed EGF-containing liposomes for molecularly targeted radionuclide delivery via ultrasound-induced cavitation
Q129589066PO-117 Increased risk of in utero x-ray exposure to mice treated with n-ethyl-n-nitrosourea postnatally
Q129587138PO-117 Role of NFE2L3 in colon cancer by regulating cancer cells proliferation
Q129588688PO-118 Impact of parity on neutron-induced mammary cancer risk in sprague-dawley rats
Q129587234PO-118 The expression of the calcium-sensing receptor in colon organoids
Q129589200PO-119 Accelerated glutamine metabolism is conferring radioresistance to prostate cancer
Q129587400PO-119 Ferritin heavy subunit enhances apoptosis of non-small cell lung cancer cells through modulation of a miR-125B/P53 axis
Q129588191PO-120 Metastatic breast cancer: underlying molecular mechanisms of radiation response
Q129586229PO-120 Proline rich homeodomain protein is required for cholangiocarcinoma tumour growth
Q129585994PO-121 ALK dependant phosphoproteome and gene expression profiling of neuroblastoma cells
Q129589197PO-121 Lentivirally-delivered ShRNA knockdown of CXCL12 prevents fibrosis in a rodent model of radiation late adverse effects
Q129588527PO-122 Synemin is a novel co-regulator of non-homologous end joining in head and neck cancer cells
Q129588074PO-123 Constitutive expression of FAT1 gene inhibits the invasion and tumorigenicity of cervical cancer cells through degradation of HPV E6/E7 oncoprotein via P53/RB in vitro and in vivo
Q129589333PO-124 MIR-1246 mediates crosstalk between DNA damage repair and the ups in autophagy to regulate the sensitivity of non-small cell lung cancer to radiation
Q129587100PO-124 PTTG and PBF functionally interact with P53 and predict overall survival in head and neck cancer
Q129585890PO-125 FAT1 on salvador-warts-hippo (SWH) pathway in human glioblastoma
Q129588633PO-125 Role of NRF2 in breast cancer stem cells resistance and tumourrecurrence
Q129586782PO-126 Exploration of novel regulators of mutant P53
Q129587261PO-126 Survival probability of human breast carcinoma cells to radiation treatment: role of cell fusion and of a syncytin1-homologous protein
Q129587938PO-127 Investigating the response of normal and cancer bladder cells to radiotherapy
Q129586242PO-127 Role of the NEDD4 family of E3 ubiquitin ligases in colorectal cancer pathogenesis and their potential as biomarkers
Q129588609PO-128 Identification of the E3 ubiquitin ligase ITCH as a novel regulator of connexin 43 degradation and gap junction intercellular communication
Q129586845PO-128 MicroRNA-449A enhances the radiosensitivity of prostate cancer cells
Q129586798PO-129 In vitro radiosensitivity and repair kinetics of PBMCs from prostate cancer patients and healthy donors evaluated by comet assay
Q129586680PO-129 Transfection with liver-type glutaminase (GAB) sensitiseshuman glioblastoma cell lines to hydrogen peroxide by downregulation of the PI3K/AKT pathway
Q129586211PO-130 SER235 residue drives eIF6 oncogenic activity in NPM-ALK induced T cell lymphomagenesis
Q129588119PO-131 Over expression of extracellular matrix protein 1 (ECM1) in muscle-invasive bladder cancer
Q129588520PO-131 Reprogramming of cancer cell metabolism by adaptation to chronic cycling severe hypoxia increases radiation resistance
Q129587892PO-132 Alpha5 beta1 integrin provides glioma cell resistance to EGFR tyrosine kinase inhibitors. role of membrane trafficking
Q129589272PO-132 Dissecting the radiobiology of targeted radionuclide therapy reveals an intra-tumoral heterogeneic response in a preclinical in vivo model
Q129588494PO-133 Hoxa9 transcription factor: a potential novel therapeutic target in renal cell carcinoma (RCC)
Q129589269PO-134 Cytogenetic and molecular characterisation of new high-grade serous ovarian cancer cell line OVPA8
Q129587401PO-134 Radiosensitizing effect of gold-based nanoparticles for brain tumourtreatment
Q129587953PO-135 Analysis of the transforming activity of human cancer identified Vav1 mutants prove its classification as an oncogene
Q129586079PO-135 GEF-X is an independent prognostic factor of gastric cancer associated with cancer stem cell development and radioresistance using multi-omics data
Q129588859PO-136 SOX2 is a novel biomarker for high-risk ewing sarcoma
Q129587444PO-136 Studying pathway interactions and dynamics to predict cell responses to chemotherapeutic treatment in breast cancer cells
Q129588694PO-137 Computational metabolism modelling predicts risk of relapse in breast cancer patients
Q129587419PO-137 Liver specific NEMO ablation induces mixed hepatocellular-cholangiocarcinoma in MYC-overexpressing mice
Q129586872PO-138 Dimethyl fumarate modulation of antioxidant response in cancer cells: therapeutic applications
Q129588537PO-138 Hedgehog signalling pathway activity in high-grade serous ovarian carcinoma
Q129585855PO-139 Identify rational drug combinations for triple negative breast cancer by integrative network modelling
Q129589106PO-139 Investigating unusual synthetic lethalgenes in acute lymphoblastic leukaemia
Q129586795PO-140 Cellular localization of survivin influences the response of colorectal cancer cells to topoisomerase I inhibitors
Q129585830PO-141 FAT1 acts as an oncogene and regulate the expression of miR-221/222–3 p in glioblastoma
Q129586020PO-141 The onocogenic kinase Pim2 as target in hepatocellular carcinoma
Q129586078PO-142 RNAi-mediated therapeutic knockdown of the neuropilin axis and GIPC1 in pancreatic carcinoma
Q129586852PO-143 Frequent loss of annexin A1 expression in head and neck squamous cell carcinomas by transcriptional regulatory mechanisms
Q129588756PO-143 Recurrent transcriptional remodelling events represent clinically actionable targets in breast cancers brain metastasis
Q129585981PO-144 HGF/c-met signalling pathway downregulates lncRNA HOTAIR to induce adhesion independent growth in HCC by increasing caveolin-1 expression
Q129587210PO-144 Role of increased expression of brain and acute leukaemia, cytoplasmic (BAALC) in acute myeloid leukaemia (AML) DNA damage repair pathways
Q129589315PO-145 ERK5 pathway inhibitors inhibit the maintenance of chronic myeloid leukaemia stem cells
Q129588653PO-146 Knockout validation of antibodies to components of the NF-kB signalling pathway
Q129589296PO-146 Multiple myeloma-derived exosomes carry amphiregulin and are responsible for the uncoupled bone remodelling
Q129587224PO-147 Pinostilbene hydrate suppresses human oral cancer cell metastasis via downregulation matrix metalloproteinase-2 through the mitogen-activated protein kinase signalling pathway
Q129585969PO-148 Activin a upregulation mediated by P63 promotes migration and invasion of oral cancer cells
Q129589185PO-148 Suppression of carnosine on adhesion and extravasation in human colorectal cells
Q129589052PO-149 Expression profiling of TP53, TP73, NME and GLI families of genes/proteins in metastatic melanoma
Q129589384PO-149 Vimentin in epithelial cancer cells during adaptation to the growth in vitro
Q129586838PO-150 Modulation of the expression of casein kinase i isoform alpha in the initiation and progression of prostate cancer
Q129586678PO-150 Tomatidine inhibits human osteosarcoma cells metastasis by down-regulation of presenilin-1 and the Raf/MEK/ERK pathway
Q129588790PO-151 Notch signalling differentiates disease-free survival in prostate cancer patients by affecting the epithelial-to-mesenchymal transition-associated processes
Q129589150PO-151 Variation of ribosome composition and translational reprogramming during human mammary epithelial-to-mesenchymal transition
Q129587883PO-152 Differentiation of lung squamous cell carcinoma (LUSC) and lung adenocarcinoma (LUAD) by gene co-expression analysis of notch signalling targets
Q129587291PO-153 Investigating tobacco smoking differential effects on lung and bladder cancer
Q129586539PO-153 SOX9 regulates epithelial to mesenchymal transition and self-renewal in pancreatic adenocarcinoma promoting metastasis and chemoresistance
Q129588310PO-154 Gene expression profile in tumour cells exposed in vitro to photodynamic therapy with a novel porphyrinic compound
Q129586814PO-154 Progesterone through progesterone receptor-B inhibits invasion of human breast cancer cells by targeting cytoplasmic cyclin D1
Q129586570PO-155 Study of the effect of pentraxin 3 on the metastasis-related protein of human osteosarcoma cell lines
Q129588784PO-155 Therapeutic evaluation of HEDGEHOG-GLI signalling pathway through miRNA and mRNA profiling of ovarian carcinoma
Q129586697PO-157 Estimation of functional effector genes reveals disease mechanisms in breast cancer in very young women
Q129586574PO-158 Extracellular vesicles, generated from UVA-exposed melanoma cells, promotes cell proliferation and invasion
Q129587216PO-158 Induction of interferon signalling by natural DNA-binding compounds with cancer preventive activity
Q129588825PO-159 Deciphering the function of endogenous E-cadherin glycosylation during ovarian cancer spread
Q129588743PO-159 Expression profiles of P53/P73 isoforms in human melanoma cell lines
Q129586589PO-160 Downregulation of the oncofetal gene SALL4 in melanoma leads to invasion and metastasis by differential acetylation mediated through binding to HDACs
Q129589098PO-160 Investigation of ubiquitin-ligase HUWE1 in the modulation of RAS pathway in leukaemia models
Q129587205PO-161 Cancer cell migratory phenotype characterisation on IGDQ-expressing surface
Q129589229PO-161 The AMPK and MEK/ERK signalling pathways regulate mitochondrial FOXO3A import through phosphorylation of serine 12 and serine 30
Q129588025PO-162 Long non coding RNA H19 (IncH19) is required for the hypoxia mediated multiple myeloma progression
Q129586728PO-162 The transcription factor GATA4 is overexpressed in malignant meningioma enhancing proliferation via downregulation of miR-15 family members
Q129589266PO-163 Identification of candidate genes underlying soft tissue sarcoma progression using a progression series of murine fibrosarcoma cell lines
Q129586026PO-163 Junctional adhesion molecule-a is a novel upstream regulator of human epidermal growth factor receptor-3 signalling in breast cancer
Q129588782PO-164 Modulation of EGFR to overcome tumour resistance and improve radiotherapy response in HPV positive and negative head and neck cancer cells
Q129586018PO-165 Effect of notch pathway and Skp2 inhibition in cell viability/proliferation of medulloblastoma cells
Q129588030PO-165 Estetrol reduce cell migration and proliferation in two/three-dimensional T47D breast cancer cell model
Q129586025PO-166 Polyol pathway connects glucose metabolism with cancer differentiation and EMT
Q129589246PO-166 The expression of nicotinate nucleotide pyrophosphorylase is elevated in colorectal cancer tissues
Q129586659PO-167 Metabolomics biomarkers in breast cancer tumours treated with neoadjuvant therapy
Q129586839PO-167 MicroRNA- 200 c, a tumour suppressor that modulate the expression of cancer stem cells markers and epithelial-mesenchymal transition in colorectal cancer
Q129588069PO-168 IKBKE regulates TSC1 for the activation of mTOR/S6K pathway in tumour cells
Q129587197PO-168 Loss of the MCC gene expression promotes invasiveness of colon cancer cells
Q129585801PO-169 Involvement of neurotensin and neurotrophins pathways in human colorectal cancer cells 5-fluorouracil treatment resistance
Q129585162PO-169 Rethinking the EGF-mediated tensin switch in colorectal cancer
Q129585737PO-170 A Suv39H1-low chromatin state drives migratory cell populations in cervical cancers
Q129586623PO-170 Dissecting the role of IFITM1 in response to anticancer treatment
Q129588065PO-171 Identifying IFITM1-dependent synthetized proteins in interferon gamma stimulated cells
Q129587863PO-171 Tissue specific extravasation and invasion of MDA-MB-231 cells in a lab-on-a-chip system
Q129586197PO-172 Role of lithocholic acid-induced cell signalling in oesophageal cancer progression model
Q129589103PO-173 Critical requirement of the Sos1 and Sos2 RasGEFs for maintenance of mitochondrial homeostasis
Q129589058PO-173 Sialylation of integrin alpha 2 promotes ovarian cancer cells metastasis
Q129589450PO-174 ErbB2 glycosylation landscape in gastric cancer cells – a novel functional target?
Q129588651PO-174 Evaluation of immunohistochemical expression of microfibrillar-associated protein 5 (MFAP5) in invasive breast carcinoma of no special type
Q129585796PO-175 Effects of trastuzumab and afatinib on kinase activity in gastric cancer cell lines
Q129589201PO-175 The secretary miR-141 facilitates ovarian cancer metastasis through reprogramming stromal fibroblast cells in pre-metastatic niches formation
Q129586647PO-176 Hepatocyte growth factor activator inhibitor-2 suppresses human prostate and lung cancer cell invasion and metastasis
Q129588468PO-177 New targets in triple negative breast cancer: role of oncostatin m receptor pathway
Q129586221PO-177 The novel function of DUSP2/VEGF-C axis in pancreatic cancer progression
Q129586356PO-178 Androstenedione (4AD) activates an androgen receptor (AR) mediated transcriptome and AR interactions associated with cell-cell adhesion in aromatase inhibitor (AI) resistant breast cancer cells
Q129588130PO-178 WDR5 promotes metastasis dissemination in breast cancer
Q129587292PO-179 Breast cancer cells and macrophages in a paracrine-juxtacrine loop
Q129589293PO-179 Identification of C-Met and insulin receptor heterodimer as a mediator for hepatocellular carcinoma
Q129589105PO-180 Dissecting the effects of EGF starvation on EGFR signalling in the mouse small intestine using 3D organoid culture systems
Q129587165PO-180 Transforming growth factor beta 1activates cell migration through the down-regulation of PRH/HHEX expression
Q129587541PO-181 Anaplastic lymphoma kinase addictive neuroblastoma cell lines are associated with growth upon treatment with MEK inhibitor trametinib
Q129586792PO-181 Predicting homing ability of hepatocellular carcinoma cells by using a lab-on-a-chip system
Q129589307PO-182 Examining the function of PDGFRB in anaplastic large cell lymphoma
Q129589176PO-182 The upregulation of EPDR1 is related to tumour invasiveness in a cohort of localised colorectal cancer patients
Q129586717PO-183 Identification of differentially hypomethylated genes associated to metastasis behaviour in colorectal cancer
Q129585823PO-183 Prolactin activation of JAK2/STAT3 signalling pathway through GHR in NSCLC
Q129587411PO-184 Proteomic profiling to predict response towards therapeutic monoclonal antibodies in HER2 low breast cancer
Q129588503PO-184 Role of ubiquitin-conjugating enzymes in chromosome instability and breast cancer metastasis
Q129589298PO-185 Non-canonical S727 STAT3 PTM activation governs its dimerization and downstream function in triple negative breast cancer
Q129586695PO-186 Generation of the GLI1, GLI2 and GLI3 knock-out ovarian cancer cell lines using the CRISPR/Cas9
Q129587348PO-186 In vitro and clinical studies of the role of MHC class II invariant chain (CD74) in breast cancer
Q129588512PO-187 Defective liver regeneration ability of Sos1-KO and Sos1/2-DKO, but not Sos2-KO mice
Q129587104PO-187 Liquid-phase polarity facilitates attachment, adhesion and metastasis of tumour cells
Q129586038PO-188 Loss of uPAR function and suppression of malignant cell behaviour by a GPI-specific phospholipase C
Q129588759PO-189 Optimisation of a lab-on-a-chip device and method for quantification of extravasation
Q129588022PO-190 In silico and in vitro screening of polyphenolic compounds for their mTOR modulatory capacity
Q129585939PO-191 Effects of non-canonical activation of protease-activated receptor 1 (PAR1) in melanoma cell lines
Q129588705PO-192 The EMT factor zeb1 promotes adenoma formation through the inhibition of cell senescence and apoptosis
Q129586147PO-193 The effect of chemotherapy induced intercellular communication on breast cancer metastasis
Q129586591PO-194 Identification of regulatory circuits specific to breast cancer development by enrichment based circuit finder
Q129585808PO-195 Integrative analysis of in vivo models of pancreatic cancer reveals complex mechanisms behind treatment failure and provides new tools for effective targeting
Q129588657PO-195 Investigation of the roles of CD90 protein in cell migration, invasion, and colony-forming ability of cancer cells
Q129585877PO-196 Identification of novel molecular players of GBM cell dispersal through an in vitro profiling approach
Q129587572PO-196 Vav1 and Mutant K-Ras synergize in pancreatic ductal adenocarcinoma development: lessons from mouse models
Q129586089PO-197 A possible link between the mitochondrial gatekeeper pyruvate dehydrogenase enzyme complex and EMT
Q129586796PO-197 Patient-derived xenograft (PDX) models of glioblastoma: from basic research to preclinical studies
Q129587901PO-198 Flavopereirine suppresses colorectal cancer growth via inducing cell cycle arrest and apoptosis in P53 signalling dependence
Q129586006PO-199 Lysyl oxidase in head and neck cancer: metastasis and therapy response
Q129588725PO-199 Platelet aggregate formation in a novel murine preclinical glioma model depends on podoplanin expression on tumour cells
Q129589445PO-200 3D In vitro cultures of PDX-derived tumour for anti-cancer drug discovery
Q129589452PO-200 Prevention of melanoma brain colonisation by inhibiting cytokines secretion from activated astrocytes
Q129589243PO-201 Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase
Q129588764PO-201 NF1 inhibits glioma cells invasion and reverts mesenchymal transition
Q129587908PO-202 PI3K activation in neural stem cells drives tumourigenesis which can be ameliorated by targeting the cAMP response element binding (CREB) protein
Q129586803PO-202 The role of RhoG in migration and invasion of astrocytoma cells
Q129586700PO-203 Peroxiredoxin 5 in colon cancer promotes epithelial-mesenchymal transition
Q129587207PO-204 The contribution of epithelial to mesenchymal transition (EMT) to the metastases of pancreatic cancer
Q129588946PO-204 Vascular effects of targeted photodynamic therapy of human glioblastoma with theranostic AGuIX nanoparticles
Q129589303PO-205 Characterisation of the integrin alpha v-dependent adhesome in mda-mb-435s melanoma cells
Q129589196PO-205 Functional characterisation of BRIP1/FANCJ in tumour suppression and therapy response
Q129586012PO-206 Calponin 3 (CNN3) promotes epithelial to mesenchymal transition and drug resistance of colon cancer cells
Q129586866PO-206 Modelling T cell acute lymphoblastic leukaemia using CRISPR/Cas9 mediated genome editing in Xenopus tropicalis
Q129589435PO-207 Ferritin-engineered nanoparticles as targeted drug delivery system for cancer treatment
Q129588641PO-207 The role of RSU-1 in glioma cells metastasis
Q129587412PO-208 Emerging roles of HECT type E3 ubiquitin ligase smurf2 in cancer
Q129588148PO-208 Human zebrafish xenografts as therapy sensors for breast cancer
Q129587273PO-209 Biological characterisation of specific KRAS mutations: from basic biology to response to treatment
Q129586740PO-209 CRISPR/Cas9 based development of RNAi rat models for drug discovery
Q129588262PO-210 Anticancer drug-induced senescence in glioblastoma cells is associated with changes in DNA repair capacity
Q129588031PO-210 Synergy between the KEAP1/NRF2 and PI3K pathways drives non-small cell lung cancer with an altered metabolism
Q129587418PO-211 KRAS driven lung adenocarcinoma depends on ERBB signalling
Q129586543PO-211 Profiling the alternative splicing landscape of senescent cells
Q129589270PO-212 Morphological heterogeneity of hepatosplenic gamma/delta T-cell lymphoma
Q129589301PO-213 High glucose affects ER +breast cancer cell metabolism
Q129588534PO-213 Sigma receptors: development of novel therapeutic approaches in pancreatic cancer
Q129589100PO-214 Combination of molecular hydrogen (H2) and 5-FLUOROURACIL (5-FU) in cancer treatment
Q129587477PO-214 Conditional control of MITF reveals cellular subpopulations essential for melanoma survival and recurrence in new zebrafish models
Q129586528PO-215 Patient-derived and cell line xenograft growth in the B6;129-Rag2tm1FwaIL2rgtm1Rsky/DwlHsd (R2G2) mouse model
Q129588117PO-215 Resistance to retinoids – analysis of putative biomarkers in neuroblastoma cells and tumour tissue samples
Q129589335PO-216 Chemotherapeutic tolerability and oestrogen dose response in the B6;129-Rag2tm1FwaIL2rgtm1Rsky/DwlHsd (R2G2) mouse model
Q129589418PO-216 Metabolic and molecular programming induced due to hyperglycemia in breast cancer
Q129588033PO-217 Loss of Kmt2c methyltransferase activity contributes to prostate tumorigenesis in a mouse model of prostate cancer
Q129585907PO-217 Tumour suppressor function of the oxidoreductase p66Shc in BRAFV600E-transformed cells
Q129587878PO-218 Cytokine-transgenic NOG mice engrafted with human peripheral blood cells support natural killer cell expansion
Q129589417PO-218 MicroRNA in mitochondria of multidrug resistant hepatocellular carcinoma
Q129586833PO-219 Methylglyoxal-induced dicarbonyl stress: role in melanoma progression and response to therapy
Q129587301PO-219 New cell genetic tracing and single-cell tools for the study of the molecular pathways involved in cancer metastasis
Q129588038PO-220 Defining the role of heparanase in breast cancer progression using the PyMT-MMTV mouse model
Q129588528PO-220 RAN, a novel and promising gene for malignant pleural mesothelioma
Q129589222PO-221 Mouse models of lung squamous cell carcinoma for preclinical intervention studies
Q114978891PO-221 Prostate cancer cells are able to use fructose as a metabolic source
Q115036812PO-222 Molecular characterisation of low grade lymphoma in northern sea otters (Enhydra lutris kenyoni)
Q129587407PO-222 Targeting cancer cell metabolism in melanomas: metabolic profiling and 3-bromopyruvate sensitivity screening
Q129586865PO-223 Modelling malignant mesothelioma in mice: a critical role for BAP1 loss
Q129587574PO-224 Fourier transform infrared spectroscopy-based detection of hypoxia-induced biomolecular changes in different cancer cell lines
Q129587862PO-224 consequences of FOXP1-mediated transcriptional repression of the mitotic checkpoint gene MAD2 in breast cancer
Q129588023PO-225 Dual role of methylglyoxal, a glycolysis side-product, in cancer
Q129587387PO-226 Dicarbonyl stress induces ECM remodelling and MAPK signalling activation in metastatic breast cancer cells
Q129587890PO-226 Integrated analysis highlights APC11 protein expression as a likely new independent predictive marker for colorectal cancer
Q129586016PO-227 Sensitising glioma cells to fatty acid oxidation inhibitor by modulation of SLC22A5 transporter activity
Q129586554PO-227 The effect of chronic mild hypoxia on genomic instability in HER2-overexpression breast cancer cell line SK-BR-3
Q129588715PO-228 Comprehensive molecular characterisation of TNBCs expressing HORMAD1, a driver of homologous recombination deficiency
Q129588101PO-228 Regulation of GDE2 membrane localization and trafficking
Q129588086PO-229 The fatty acid desaturase SCD1 as crucial factor for tumour progression in colon cancer
Q129589434PO-229 Transient tissue ‘priming’ via FAK inhibition to impair pancreatic ductal adenocarcinoma (PDAC) progression to improve sensitivity to gemcitabine/abraxane
Q129587313PO-230 Cysteine-rich secretory protein 3 regulates progression from in situ to invasive prostate cancer
Q129589111PO-230 Effect of C. cochinchinense extract on V-ATPase inhibition triggering apoptosis in human cancer cell lines
Q129586650PO-231 CTXIII expression around single tumour cells of invasive breast carcinoma
Q129585849PO-231 mTOR activity differences and related metabolic activity in human breast cancer cell lines
Q129587382PO-232 Actin-dependent effect of tumour suppressor P53 on human lung cancer cell malignant characteristics
Q129588677PO-232 Lewis glycans and their epigenetic regulation are associated with neuroblastoma aggressiveness
Q129586239PO-233 Chemoresistant NSCLC cells are hypersensitive to metabolic drugs due to mTOR-mediated inhibition of autophagy
Q129588519PO-233 DOCK1 as a novel molecular target for controlling cancer cell survival and invasion
Q129586582PO-234 Transwell co-culture with human breast adipocytes alters the proteome expression profiles of MCF-7 and MDA-MB-231 human breast cancer cells
Q129587333PO-235 Fenofibrate overcomes the drug-resistance of human prostate cancer cells
Q129586024PO-235 Integrin beta-like 1 overexpression stimulates invasiveness of ovarian cancer cells in vitro
Q129586898PO-236 Human ligase profiling to predict platinum sensitivity and clinical outcome in primary epithelial ovarian cancers
Q129588471PO-237 Neutralising extracellular morgana impairs breast tumour growth and migration
Q129587375PO-237 The pro-oncogenic transcription factor STAT3 regulates Ca2 +release and apoptosis from the endoplasmic reticulum via interaction with the Ca2 +CHANNEL IP3R3
Q129588044PO-238 Clinicopathological significance of EMT markers in thymic epithelial tumours
Q129586136PO-238 Dichloroacetate (DCA) treatment affects mitochondrial activity and stemness in pancreatic cancer (PC) cell lines
Q129586291PO-239 Benzo(a)pyrene, an active product of cigarette smoke, role in PLA2 isoforms activation in colon cancer
Q129587456PO-239 Towards identifying key drivers of breast cancer metastasis to the bone
Q129589309PO-240 Targeting cancer stem cells in mammary triple negative cell line by retinoids and lapatinib treatments
Q129588684PO-240 WWOX suppressor gene regulate glucose metabolism and warburg effect in case of gestational diabetes mellitusas well as breast cancer
Q129588628PO-241 Prognostic factors for operable biliary tract cancer: serum levels of lactate dehydrogenase: a strong association with survival
Q129586643PO-241 Targeting fatty acid oxidation and glycolysis to overcome drug resistance to MAPK inhibitors
Q129588040PO-242 Myoferlin controls mitochondrial structure and metabolism in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness
Q111491250PO-242 Novel analysis of cancer cell invasion using a three-dimensional cultured tissue model mimics human tissue organisation
Q129588761PO-243 Exosomes from plasma of HNSCC patients treated with photodynamic therapy are biomarkers for epithelial-mesenchymal transition
Q129586120PO-243 Uncoupling FOXO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy
Q129586609PO-244 Catechol-O-methyltransferase: a dual-role player in different breast cancer subtypes?
Q129588500PO-245 Fructose supports tumour growth and aggressiveness through a metabolic reprogramming in prostate cancer
Q129587584PO-245 Vimentin expression as a sign of epithelial-mesenchymal transition in prostate cancer
Q129588836PO-246 AXL receptor tyrosine kinase expression as a prognostic marker and therapeutic target in neuroendocrine tumours
Q129588118PO-246 Nandrolone affects cell growth and differentiation in hepatoma cells
Q129587919PO-247 Mesothelin regulates invasion and peritoneal metastization of ovarian cancer
Q129588258PO-248 Novel insights on the role of glycosylation in cancer: molecular functions and clinical applications
Q129586696PO-248 The role of ER stress in arginine deprivation-induced radiosensitization and cell death of HNSCC cells
Q129588108PO-249 GLUL knockdown induces drug resistance in non-small cell lung cancer cells
Q129588721PO-249 Phylogenetic relationships between paired primary papillary thyroid carcinomas and distant metastasis: intra-tumour molecular heterogeneity and clonal evolution
Q129587349PO-250 Investigating BRF2-dependent RNA polymerase III transcription deregulation in cancer
Q129589383PO-250 Phospho S82 Hsp27: a marker of invasive and recurrent non-functioning pituitary adenoma
Q129588170PO-251 High density fibrillar collagen promotes breast cancer cell invasion by decreasing actin dynamics at invadopodia
Q129587397PO-251 Modulation of NAD+levels by NQO1 enzymatic action alleviates adriamycin-induced cardiac dysfunction in mice
Q129585806PO-252 Impaired glucose metabolism in human glioma stem cells upon treatment with a cell-penetrating peptide based on CONNEXIN43
Q129586533PO-252 The circuit of oncofetal O-glycosylation, galectin-4, RTK, and MYC drives metastatic castration-resistant prostate cancer
Q129589113PO-253 Characteristics of cellular respiration, glycolytic activity and related metabolic features in wild type and IDH1 mutant glioma cells
Q129586553PO-254 G protein-coupled oestrogen receptor activation decreases prostate cancer cells viability concomitantly with altered proliferation, apoptosis, and metabolic profile
Q129588649PO-254 Merkel cell polyomavirus T-antigen regulate microRNAs post-transcriptionally through DICER in merkel cell carcinoma
Q129585881PO-255 The pivotal role of glutaminolysis in prostate cancer cells and its regulation by androgens
Q129588488PO-255 The role of solid stress in tumor-stromal interactions
Q129589198PO-256 The extracorporeal immunopharmacotherapy (EIPHT) and remote results of cervical cancer and ovarian cancer treatment
Q129587413PO-257 Loss of the mitochondrial pyruvate carrier drives ‘glutamine addiction’, a hallmark of aggressive ovarian cancers
Q129586144PO-257 The immunoreactivity of patients with cervical cancer on the background of extracorporeal immunopharmacotherapy (EIPHT)
Q129588535PO-258 Can we treat early breast cancer without surgery? Is primary definitive hormone therapy a valid alternative for operable hormone sensitive breast cancer?
Q129589365PO-258 Telmisartan induces melanoma cell apoptosis via generation of ROS and has synergistic effects with targeted therapy in vitro
Q129586521PO-259 Identification of a clinically meaningful site-specific steroid roadmap in prostate cancer
Q129588026PO-259 Inhibition of the hexosamine biosynthetic pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis
Q129587920PO-260 Anti-lymphoma activity of novel selective glucocorticoid receptor agonists (SEGRAs) in vitro and in vivo
Q129589220PO-260 Deep phenotyping of colorectal cancers by high-dimensional mass cytometry reveals tumor-specific immune landscapes
Q129588112PO-261 Multimodal mass spectrometry imaging to understand drug delivery, metabolism, response and amp; resistance in pancreatic ductal adenocarcinoma
Q129589439PO-261 Subcellular localization and expression of NME6, a member of the NME/Nm23/NDPK family, in human tumour cells
Q129587452PO-262 Differential expression of Sphingosine-1-Phosphate metabolising enzymes in oral squamous cell carcinoma
Q129644194PO-262 Remodelling of the tumour microenvironment by pegvorhyalurondiase alfa (PEGPH20): a novel, first-in-class biologic that enzymatically degrades tumour hyaluronan (HA) to improve anti-tumour efficacy
Q129586585PO-263 Assessment of the accumulation of hyaluronan in the tumour microenvironment (TME) of solid tumours
Q129586901PO-263 Epigenetic modulation of cell metabolism and its effects on cell survival in melanoma
Q129589051PO-264 Mitochondrial metabolism: a key factor of myeloid leukemic cell response upon exposure to tyrosine kinase inhibitors
Q129588110PO-264 Preclinical studies with pegvorhyaluronidase alfa (PEGPH20) in combination with FOLFIRINOX (FFX) chemotherapy in models of pancreatic ductal adenocarcinoma
Q129586694PO-265 Cisplatin induces pro-inflammatory program and modulates pro-angiogenic potential of human tumor-associated macrophages
Q129588709PO-266 Metabolic profiling of osteosarcoma cancer stem cells as tool to identify potential target for cancer therapy
Q129588744PO-267 Notch-dependent tumourigenic mechanism associated with exosome signalling
Q129587416PO-267 PHGDH and PSAT confer metabolic vulnerability to IDH2-driven reprogramming in breast cancer
Q129588522PO-268 Adipose-derived mesenchymal stem cells microenvironment promotes the tumorigenic phenotype in triple negative breast cancer cell line
Q129587931PO-268 The interaction of hERG1 potassium channels with integrin receptors perturbs the force transduction machinery in pancreatic cancer
Q129589405PO-269 Development of a fluorescence in situ hybridization (FISH) method for detection of intra-tumour bacteria involved in pancreatic cancer chemoresistance
Q129588731PO-269 Targeting ALDH inhibition in endometrial cancer cells
Q129586556PO-270 3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment
Q129588591PO-270 Signalling pathways WNT, hedgehog and NOTCH in breast cancer with presence and absence of cancer stem cells
Q129586808PO-271 Rise of the machines: probing intercellular crosstalk with mass spectrometry
Q129586077PO-271 Using human lung organoids to study pulmonary neuroendocrine cells
Q129589216PO-272 Leukemia-associated NPM mutations promote quiescence of hematopoietic stem cells and prevent their functional exhaustion upon oncogene-induced hyper-proliferation
Q129589056PO-272 Optimisation of hypoxia regulated timed systems for genetic ablation and tracking of hypoxic breast cancer cells to study therapy resistance
Q129588878PO-273 Aldehyde dehydrogenase 7A1 (ALDH7A1) contributes to reduction of reactive oxygen species generation in colorectal tumour microenvironment
Q129589096PO-273 Evaluation of the role of SOX2 as cancer stem cell marker in sarcomas
Q129589353PO-274 Development of an in vitro tumour model to evaluate drug efficacy and epithelial mesenchymal transition in triple negative breast cancer
Q129586857PO-274 Tumour subtype-specific cells of origin of malignant mesothelioma
Q129586145PO-275 Effect of ionising radiation in FaDu cell line- preliminary results
Q129589242PO-275 Gene expression and splicing variants changes in colorectal cancer related cell function pathways
Q129589227PO-276 Histone acetylation readers BET in hypoxia adaptation in triple negative breast cancer (TNBC)
Q129587585PO-276 Prognostic significance of LGR5, an intestinal stem cell marker, in colorectal cancers. (running head: LGR5 in colorectal cancers)
Q129588643PO-277 Postmitotic neuron-like differentiation of cancer cells suggests that cancer cells have the properties of neural precursor/progenitor cells
Q129587527PO-277 Single-cell RNA-seq analysis of human pancreatic ductal adenocarcinoma
Q129586519PO-278 Assessment of the influence of stellate cells on primary pancreatic cancer cell growth and drug resistance in a spheroid model: MET inhibitors to the rescue
Q129587985PO-278 Distinctive role of dysregulated miRNAs and mRNAs in chordoma cancer stem cells
Q129589456PO-279 Effect of the in vitro A549 neuroendocrine differentiation on the activity cytotoxic T lymphocytes
Q129586410PO-279 Interplay between Indoleamine 2,3-dioxigenase 1 and Notch1 in radiation response of cervical stem cancer cells
Q129588713PO-280 Hypoxia-induced PLD2 promotes tumorigenesis and stem cell-like properties in tumour cells
Q129586789PO-280 Mutant KRAS mediates fibroblast-induced colorectal cancer cell invasion
Q114978888PO-281 Automated multiparametric tissue imaging platform using existing microscope hardware for the detection of spatially resolved single-cell resolution data
Q110698997PO-281 SIRT1 inhibition exhibits decreased pluripotency in glioma cancer stem cells
Q129588623PO-282 Cancer-associated fibroblast-derived lumican promotes gastric cancer progression via the integrin beta1-FAK signalling pathway
Q129588070PO-282 SMAR1 transcriptionally repress hTERT and alters the stem cell population in colorectal cancer cells
Q129588603PO-283 Characterisation of hTERT-immortalised prostate-derived stromal and epithelial cells: an authentic in vitro model for tumour microenvironment studies
Q129589499PO-283 The Akt/mTOR pathway in cancer stem/progenitor cells is a therapeutic target for glioblastoma and neuroblastoma
Q129587248PO-284 Involvement of versican, a chondroitin sulfate proteolgycan in the pathogenesis of multiple myeloma
Q129589414PO-285 Immunomodulatory effects of lactobacillus strains: emphasis on identification of probiotic candidates with anti-tumour responses
Q129588089PO-285 Role of tumour associated macrophages (TAMs) in regulation of cancer stem cell (CSCs) enrichment in breast cancer
Q129588470PO-286 Evaluating the influence of mesenchymal stromal cells derivatives on early stage of breast cancer
Q129588077PO-286 Protein kinase D3: a crucial regulator of breast cancer stem cell survival
Q129588746PO-287 A novel L1/STAT3 crosstalk drives ovarian cancer stem cell function
Q129588080PO-287 ’Annex’in A1 to the breast tumour microenvironment by aiding in macrophage polarisation
Q129585803PO-288 Replication stress response as a target for eradicating colorectal cancer stem cells
Q129587916PO-288 Stroma cells increase expression of tumor-promoting RAC1B in colorectal cancer cells
Q129587588PO-289 Identification of microenvironmental regulation and therapeutic targeting of ongenic EF-2 kinase in pancreatic cancer
Q129586847PO-290 ETV7 regulates breast cancer stem cells content and chemoresistance
Q129589262PO-290 Oncostatin M signalling mediates the crosstalk between cancer cells and tumour microenvironment and promotes breast cancer progression
Q129585935PO-291 A cell-penetrating peptide based on the connexin43-Src interacting sequence reduces glioma stem cell migration and proliferation by recruiting Src, Csk and PTEN
Q129587153PO-291 The disbalance of the basic cytokines of the immune system in patients with ovarian cancer on the background of immunotherapy
Q129585726PO-292 Breast cancer stem cell reprogramming: deciphering the impact of glucose and the contribute of tumour microenvironment
Q129589411PO-293 Tumour/stroma interactions in colorectal cancer (CRC) models: role of the tumour suppressor PTEN
Q129586119PO-293 Withaferin-A: a candidate anti-tumour natural compound for non-small cell lung cancer and stem cells
Q129588834PO-294 Role of fatty acid amide hydrolase (FAAH) in breast development and cancer
Q129585867PO-295 Heterogeneity of the alpha5 integrin subunit expression in glioblastoma
Q129586751PO-296 Elucidating the potential role of CD109 as a biomarker for cancer stem-like cells in cervical cancer
Q129586098PO-296 Identification of novel players of tumour – macrophage crosstalk in lung cancer
Q129587284PO-297 Oncogenic activity of SOX1 in gastric cancer
Q129588493PO-297 PLEXINA4 plays a role in cancer progression and immune cell infiltration
Q129588593PO-298 MYC favours the onset of tumour initiating cells by inducing epigenetic reprogramming of mammary epithelial cells towards a stem cell-like state
Q129587606PO-298 Pegylated recombinant human hyaluronidase PH20 (PEGPH20) increases tumour uptake and efficacy of cetuximab in a human pancreatic cancer xenograft model
Q129589559PO-299 Aberrant TXNDC5 expression in colon stromal fibroblasts promotes colorectal cancer carcinogenesis
Q129588720PO-299 In vivo shRNA screening to identify quiescence-related genes required for AML growth
Q129586142PO-300 CIP2A-mediated regulation of senescence in basal-like breast cancer
Q129588087PO-300 Unveiling and exploiting cancer stem cell editing and immunogenicity for precision medicine
Q129587169PO-301 Diagnosis of glioma tumours using circulating cell-free DNA
Q129587899PO-301 Protein disulfide isomerase A4 regulates cancer development via cancer stromal cells
Q129586223PO-302 Deconvolution of the tumour microenvironment of primary human pancreatic ductal adenocarcinoma and normal pancreas reveals specific deregulated signalling nodes
Q129586902PO-302 The role of SPARCL1 in upper urinary tract cancer of Taiwan
Q129587154PO-303 Germline determinants of the somatic mutation landscape in 2642 cancer genomes
Q129588122PO-303 Modified P53 functionality in cancer-associated fibroblasts promotes cancer growth
Q129586514PO-304 Three-dimensional co-culture of colorectal cancer spheroid with cancer-associated fibroblast as a model to study immune cell modulation
Q129585897PO-305 Chromatin accessibility profiling identifies an underlying HNF4A-GATA6 regulatory module in oesophageal adenocarcinoma
Q129587233PO-305 Depletion of CPEB4 in the metastatic niche enhances metastatic growth
Q129589313PO-306 Identification of chromatin modifiers regulating temozolomide resistance in glioblastoma multiforme
Q129589192PO-306 Targeting CD70-positive cancer associated fibroblasts to tackle the immune suppressive tumour microenvironment in colorectal cancer
Q129587464PO-307 Differential secretome analysis of cancer-associated adipocytes (CAA) and mature adipocytes to identify adipocyte-driven micro-environmental regulators of breast cancer progression
Q129585947PO-307 Paradoxical decrease in H2AFX copy number yet increasing mRNA expression in human breast cancer
Q129587113PO-308 HAF inhibition in glioma cells reduces tumour growth without modifying the efficacy of chemo- and radiotherapy
Q129586208PO-308 Identification of genomic patterns predictive of upgrading in low-grade prostate cancer
Q129588153PO-309 Identification of genomic aberrations associated with lymph node metastasis in diffuse-type gastric cancer
Q129585773PO-310 Genomic features of premenopausal breast cancers in latin american women: the PRECAMA study
Q129588075PO-310 miRNAs in tumor-derived microvesicles promote angiogenesis and tumour cell growth
Q129588183PO-311 Characterisation of colorectal tumour endothelial cells
Q129586010PO-311 Multifocality complicates molecular classification of primary prostate cancer
Q129585973PO-312 Longitudinal transcriptomics reveals heterogeneous dynamics through the course of disease and therapy in breast cancer
Q129588199PO-313 Genome-wide analysis of site-specific hotspots in cancer
Q129587600PO-313 Inhibition of neddylation accelerates VEGF-activated VEGFR2-nitric oxide signalling for resulting in biphasic effects on angiogenesis and tumour growth
Q129588738PO-314 ALK inhibitor, ceritinib, abrogates activation of the novel ALK-I1171T mutation in neuroblastoma
Q129589509PO-314 Loss of host secretory leukocyte protease inhibitor reduces lung adenocarcinoma burden
Q129588485PO-315 Intertumor heterogeneity in vascularity and response to bevacizumab treatment in artificial melanoma brain metastases
Q129585744PO-315 The mutational and transcriptome landscape of infant B-cell acute lymphoblastic leukaemia: the INTERFANT treatment protocol experience
Q129589390PO-316 Genome-wide gene expression analysis of a murine model of prostate cancer cell progression: towards identification of high-potential therapeutic targets
Q129586580PO-316 Isoquercetin: a novel agent to increases VASH1 and suppress colon cancer
Q129589280PO-317 Improved performance and workflow using sanger sequencing for low-level somatic mutation detection from low amount of formalin-fixed paraffin-embedded (FFPE) DNA
Q129588085PO-318 De novolong interspersed element (LINE-1) insertions in high-grade serous ovarian carcinoma
Q129586597PO-318 Intestine-specific homeobox gene ISX integrates IL6 signaling, tryptophan catabolism, and immune suppression
Q129585798PO-319 Mutational signatures of 1,2-dichloropropane and dichloromethane identified in mouse carcinogenicity assays
Q129587859PO-319 Role of stanniocalcin-1 on macrophage differentiation and cytokine production
Q129589165PO-320 Anti-inflammatory effects of gossypol on human lymphocytic jurkat cells via regulation of MAPK signalling and cell cycle
Q129587187PO-320 Gene panel mutation screening for a better molecular stratification of colorectal cancer patients
Q129586840PO-321 Causes and consequences of WDHD1 overexpression in breast cancer
Q129589221PO-321 MicroRNA-145 and COX2 levels are regulated by nerve growth factor (NGF) in epithelial ovarian cancer
Q129586190PO-322 Investigating co-expression of the immune checkpoints heme oxygenase-1 and PD-L in breast cancer
Q129589199PO-322 Multi-region deep sequencing of colorectal carcinoma in-situ defines oncogenic transformation as a gradual and adaptive process
Q129586544PO-323 Tumour evolution in non-muscle-invasive bladder cancer
Q129586534PO-324 Detection of high-risk prostate cancer biomarkers by RNA sequencing and qPCR method
Q129586599PO-324 Interferon regulatory factor 1 (IRF1) regulates inflammatory and metabolic phenotypes in pancreatic ductal adenocarcinoma
Q129587451PO-325 Novel recurrent high-level amplifications in microsatellite stable colorectal cancer
Q129587568PO-325 Topological-proteomics of breast cancer intra-tumour heterogeneity reveals metabolic diversity within single tumours
Q129589233PO-326 Genetic stability of multiple recurrences in bladder cancer patients
Q129585951PO-326 Impact of miR-205–5 p and miR-425–5 p on Wnt and AR signalling pathways in castration resistant prostate cancertransition
Q129587378PO-327 Whole-genome CRISPR-CAS9 screening: the wellcome sanger institute cellular generation and phenotyping pipeline
Q129588111PO-328 No such thing as a perfect copy – DNA replication profoundly influences how most environmental carcinogens and epigenetic marks induce mutations
Q129587484PO-328 Stemness features of prostate cancer cells induced by carcinoma-associated fibroblasts
Q129588149PO-329 Genomic aberration in pancreatic neuroendocrine tumours (PNET)
Q129589238PO-329 Rejecting neutral tumour evolution across human cancer types
Q129587225PO-330 Investigating tissue- and age-specific microsatellite instability in mice with different levels of MLH1, a central mismatch repair protein
Q129588478PO-330 Prevention of worsening in glioma relapse
Q129585715PO-331 Understanding DCIS initiation and progression using tumouroid and mouse models
Q129587450PO-332 Genomic landscapes, neoantigen profiles and biological impact of MLH1 inactivation in cancer cells
Q129589407PO-332 Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E-inhibition in melanoma
Q129588530PO-333 Molecular heterogenity in neuroblastoma (on behalf of turkish paediatric oncology group)
Q129587925PO-333 Somatic engineering of mammary gland epithelial cells using CRISPR/Cas9 for rapid testing of breast cancer susceptibility genes in mouse models
Q129589287PO-334 Distribution of copy number alterations defines clonal populations involved in the evolutionary transition from adenoma-to-carcinoma in colorectal cancer
Q129587947PO-334 Identification of shared lineage programs across high-grade glioma subtypes by single-cell RNA-seq
Q123121896PO-335 EGFR and ALK mutation status in advanced lung adenocarcinoma: prevalence, gender and age-related peculiarities among patients in Ukraine
Q129585868PO-335 The effect of three-dimensional (3D) cell cultures on phenotype and gene expression of EMT- and CSC-associated genes in head and neck squamous cell carcinoma cell lines
Q129587967PO-336 Identification of SOX2 and SFRP2 as opposing regulators of glioblastoma heterogeneous subtypes
Q129588777PO-337 Preliminary observations: array-comparative genomic hybridization as a high-throughput approach against bladder cancer
Q129586296PO-337 Single cell mRNA sequencing reveals the presence of the gene expression signature of all major molecular subtypes in individual breast cancers
Q129588751PO-338 Recurrent glioblastoma: a complex scenario dominated by loss of MMR proteins
Q129587327PO-338 Tumour heterogeneity underlies differential cisplatin sensitivity in mouse models of SCLC
Q129588627PO-339 Implications of organ-wise extraction of cancer mutational signatures using 2577 whole genomes
Q129586520PO-339 Intratumour heterogeneity in a pancreatic cancer mouse model
Q129589277PO-340 Dysregulation of the TP53 network and PRC2 activity are independent poor prognostic factors in patients with malignant peripheral nerve sheath tumours
Q129587457PO-340 Tumour heterogeneity in patient-derived glioblastoma organoids
Q129585919PO-341 Functional role of APOBECS in upper aerodigestive tract tumours
Q129587561PO-341 The role of cancer/testis antigens from MAGE-A family and NY-ESO-1 in ductal carcinoma in situ (DCIS)
Q129585848PO-342 Establishment and molecular profile of a new cervical cancer cell line from brazilian patient biopsy
Q129587414PO-342 Integrating copy number analysis and tumour DNA methylation profiling
Q129588857PO-343 Targeted resequencing identifies novel and ultra-rare high-impact variants in breast cancer susceptibility genes in an Irish population
Q129587895PO-343 The microRNA-146b-IRAK1 signalling axis in tumour recurrence of papillary thyroid cancer
Q129587306PO-344 Osteoblastoma is characterised by recurrent rearrangements of FOS and FOSB
Q129589274PO-344 miR-302b as adjuvant therapeutic tool to improve chemotherapy efficacy in human triple negative breast cancer
Q129585306PO-345 Identification of AR-modulatory microRNAs for prostate cancer progression and therapy
Q129586729PO-345 The role of the deubiquitinase USP11 in endocrine-driven breast cancer
Q129588205PO-346 Defining microRNA mediated regulation of metabolic pathways involved in colon cancer progression (BST1-microRNA interactions)
Q129588855PO-346 The MYC antagonist MNT beyond MAX interaction
Q129589177PO-347 Analysis of global methylation status under the microenvironment in glioblastoma cells
Q129586760PO-347 sONE, a novel tumour suppressor lncRNA, with diminished expression level in young triple negative breast cancer (TNBC) patients with lymphnode metastasis and large tumour size
Q129586633PO-348 Two novel synthetic analogues of miR-1207–3 p, NB5 and NB1207, target AR-V7 and C-MYC and demonstrate in vivo therapeutic efficacy in metastatic castrate-resistant prostate cancer (mCRPC)
Q129587390PO-349 AKT3, but not AKT1 and AKT2, confers a longer survival rate to less aggressive breast cancers
Q129587551PO-349 Identification of differentially expressed lncRNAs in metformin resistant SH-SY5Y neuroblastoma cells
Q129585853PO-350 Case-case GWAS to identify germline metastasis risk variants in sporadic colorectal carcinomas
Q129589311PO-350 MiRNAs and their relation to biological pathways in left- and right-sided colorectal cancer
Q129589548PO-351 Melatonin suppresses TPA-induced oral cancer cell migration via lncRNA-LNC310-mediated PRUNE2 activation
Q129587596PO-351 Promo: an interactive tool for analysing large multi-omic cancer datasets
Q129587648PO-352 Hijacking hepatocellular carcinoma (HCC) tumour progression through restoring TP53/miR-15a/miR-16 tumour suppressor axis by a novel quercetin glycoside
Q129586660PO-352 The effects of lapatinib responsive miRNA on cell proliferation and cell invasion in HER2 +breast cancer cell line
Q129588171PO-353 Functional high-throughput screening reveals multiple tumour-suppressive microRNAs in neuroblastoma
Q129586092PO-353 TIP60-dependent acetylation of SPZ1-TWIST complex promotes epithelial–mesenchymal transition and metastasis in liver cancer
Q129588638PO-354 Disrupting the acetylation of ISX-BRD4 by p300/CBP-associated factor (PCAF) suppresses tumour metastasis
Q129588109PO-354 Star-shaped gene silencing nanoparticles– an advanced approach to treating medulloblastoma
Q129588765PO-355 Antitumor activity of HSA-miR-X in HER2 positive cells is mediated by the regulation of AKT and ERK
Q129588769PO-355 Enhancers mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer
Q129588517PO-356 MicroRNA mediated regulation of morgana, a new oncosuppressor in chronic myeloid leukaemia
Q129586227PO-356 White blood cells from prostate cancer patients carry distinct chromosome conformations
Q129586688PO-357 miR-145–5 p, miR-196a-5p, miR-222–3 p and lncRNA MALAT1 as non-invasive markers in advanced laryngeal squamous cell carcinoma
Q129586117PO-358 CELf2 at the core of a prognostic alternative splicing signature in colorectal cancer
Q129587519PO-359 Macrophage polarisation and squamous cell carcinoma
Q129587361PO-359 Overexpression of histone H3K4 demethylases in clear cell renal cell carcinoma with LSD2 as plausible therapeutic target
Q129586529PO-360 Epigenetic changes in testicular cancer survivors treated with cisplatin
Q129588690PO-360 Vaccinia virus delivered by isolated limb perfusion combines with PD-1 blockade to prevent local and distant relapse in soft-tissue sarcoma
Q129588648PO-361 Modulation of cancer cell response to etoposide by M1 and M2 polarised macrophages
Q129588791PO-362 Influence of epigenetic agents on mouse teratoma development in vitro
Q129586896PO-362 Rational designing combinatorial T-cell based immunotherapy by high-dimensional profiling
Q129587362PO-363 Implication of global histone methylation (H3K4me) levels in the prognosis of clear cell renal cell carcinoma
Q129586313PO-364 Effect of exercise and immunotherapy on tumour immunogenicity and growth
Q129586028PO-364 LncRNA-P23154 promotes the invasion-metastasis potential of oral squamous cell carcinoma by regulating Glut1-mediated glycolysis
Q129589292PO-365 Dissecting the synergistic effect of chemotherapy and immunotherapy on anti-tumoral T cell functions in breast cancer
Q129589195PO-365 Isothiocyanates as potent epigenetic regulators in human malignant melanoma chemoprevention
Q129589203PO-366 Chemotherapy induces PD-L1 in esophageal squamous cell carcinoma
Q129586991PO-366 Long non-coding RNAs TINCR and DANCR in urothelial carcinoma subtypes
Q129587158PO-367 Brain microenvironment-secreted cytokines facilitate glioblastoma proliferation and invasion
Q129588105PO-367 DFNA5 methylation: a potential biomarker for breast cancer, on the basis of a large scale analysis in TCGA
Q129589451PO-368 Differential effects of immune activity on melanoma cell subtypes
Q129585938PO-368 Epigenetic regulation of glycosylation and the impact on chemoresistance in ovarian and breast cancer
Q129588538PO-369 Effects of cycling hypoxia on the communication between macrophages and endothelial cells in promoting tumour growth and metastasis
Q129589217PO-369 KDM3A/Ets1/MCAM axis in rhabdomyosarcoma and osteosarcoma
Q129585958PO-370 A co-culture assay system using engineered anti-CD3 tumour cells to assess tumour cell sensitivity to CD8 +T cell killing
Q129586726PO-370 Sustained over-expression of miR-26a induces chromosome instability and tumorigenesis by dysregulation of CHFR expression
Q129588159PO-371 ADAM28 deletion in mice induces CD8 +T cell decrease and impacts the onset of lung metastasis
Q129588209PO-371 Contribution of elevated miR-146b-5p to papillary thyroid cancer diagnosis and development
Q129588736PO-372 IL-2 and IL-15 cytokine in vitro treatments induce NKG2D, CD158a and CD158b receptor expression on T, NKT- like and NK cell lymphocyte subsets from regional lymph nodes of melanoma patients
Q129588536PO-372 Investigating the epigenetic changes underlying combination treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide
Q129587355PO-373 Dynamics of the esophageal tumour immune micro-environment after neoadjuvant chemoradiation (nCRT)
Q129586162PO-373 Methylation deregulation of miRNAs promoters in breast cancer in very young women
Q129589235PO-374 A 3D image-based quantification of organoid-immune cell interactions in the presence of immuno-modulators
Q129587442PO-374 LINC00152 long non-coding RNA promotes the proliferation of SW480 colon carcinoma cells through regulation of cell cycle and WNT signalling pathway
Q129587130PO-375 Analysis of miRNA expression in non-small cell lung cancer
Q129587324PO-375 Rational designing combinatorial T-cell based immunotherapy by high-dimensional profiling
Q129588090PO-376 SWI/SNF alterations as markers for prognosis and specific treatments in human cancer
Q129588674PO-377 Immune recognition of tumours by voluntary wheel running may be triggered by induction of Zbp1
Q129586843PO-377 Whole transcriptome analysis reveals colorectal cancer-associated long non-coding RNAs including UCA1 already dysregulated in colorectal adenomas
Q129587950PO-378 Exercise-dependent regulation of immune cell function in a clinical cancer perspective
Q129588885PO-378 Systematic miRNA expression changes in human colorectal cancer development and in animal model
Q129588196PO-379 Novel tumour specific miRNA expressed in classical hodgkin lymphoma cell lines
Q129586166PO-380 Epigenetically regulated MAF is a new potential tumour suppressor gene in LSCC
Q129587861PO-380 Regulatory T cells encounter pro-inflammatory immune cells in human colorectal cancer
Q129589339PO-381 Response project: chromatin regulators as biomarkers and drug targets in colorectal cancer
Q129585752PO-382 Differentially methylated sites in histologically negative surgical margins of oral squamous cell carcinoma patients
Q129585997PO-382 Evaluation of the serum level of T-helper-17 in patients with benign and malignant salivary gland tumours
Q129587918PO-383 Profile of serum heat shock protein-27 level in patients with salivary gland tumour
Q129588486PO-384 Investigation of IL-33 serum levels in patients with benign and malignant salivary gland tumours
Q129588480PO-384 Manual and automated detection of DNA methylation alterations in colorectal neoplasia in circulating cell-free DNA fraction
Q129587965PO-385 DNA methylation profile of castration-resistant prostate cancer cells
Q129586014PO-386 Decoding the regulatory role and epiclonal dynamics of DNA methylation in 1482 breast tumours
Q129587250PO-387 Differential gene methylation in triple negative breast cancer and non-tumoral mammary tissue
Q129586875PO-387 Phenotypic and functional analysis of malignant mesothelioma tumor-infiltrating lymphocytes (TILs)
Q129586114PO-388 Epigenetic silencing of ZNF177 by MIR-877–3 p could be involved in cervical cancer progression
Q129587994PO-389 Epigenomic and mutation determinants of carcinogen-driven primary epithelial cell immortalization
Q129585790PO-390 A workflow for optimised isolation and analysis of tumour infiltrating immune subpopulations
Q129589420PO-390 Image-guided stereotactic molecular profiling of samples taken in- and outside conventional tumour boundaries highlight extensive infiltration of tumour cells in diffuse gliomas
Q129588129PO-391 DNA methylation as a probable cause of SPRR3 loss in esophageal cancer
Q129588722PO-391 High-throughput single-cell T-cell receptor profiling by SMART technology
Q129588078PO-392 Epigenetic changes in chondrosarcoma caused by IDH mutations as a target for novel anticancer therapy
Q129586185PO-392 Galectin-9 is required for dendritic cell function and directly contributes to DC-mediated anti-tumour immunity
Q129588079PO-393 Identification of housekeeping genes to quantitative real-time RT-PCR analysis by miRNA expression using liquid-based cervical cytologysamples
Q129586571PO-393 Notch3 and CXCR4 cross-signalling sustains acute T-cell leukaemia progression
Q129587971PO-394 DNA methylation of ADAM23 is negatively associated with haematogenous spread in breast cancer
Q129586754PO-394 Performance of a targeted T cell receptor beta immune repertoire sequencing panel in several FFPE tissue types – a tool for interrogation of the tumour microenvironment
Q129586631PO-395 Cortisol triggers immune escape of human acute myeloid leukaemia cells by inducing expression of G protein-coupled receptor latrophilin 1 which facilitates exocytosis of immune suppressor galectin-9
Q129587583PO-395 Mechanistic investigation of epigenetic modifications induced by metabolic changes in AML
Q129588556PO-396 Soluble mediators released by human melanoma-associated fibroblasts interfere with cytotoxic T cell response
Q129586008PO-397 DNA damage tolerance is essential for the DNA damage response network and hematopoietic stem cell maintenance
Q129587352PO-398 Benchmarkingof amplicon-based next-generation sequencing panels combined with bioinformatics solutions for BRCA1 and BRCA2 alteration detection
Q129588755PO-398 Markers of immune exhaustion and immune suppression in immunoregulatory network of virus-associated cervical cancer: putative contribution in the induction of invasive tumour growth
Q129588180PO-399 Genome wide histone modification patterns at the promoter regions are distinct in low and high grade gliomas
Q129588636PO-399 Tumour CDKN2A loss predisposes to immunotherapy resistance
Q129587625PO-400 Arriba – fast and accurate gene fusion detection from RNA-seq data
Q129587108PO-400 Dual targeting of TIM3 and adenosine produces synergistic improvement in anti-tumour immunity
Q129586733PO-401 Detection of mutational patterns associated to HR deficiency from low counts of mutations
Q129587110PO-401 Tumour stem cell characteristics are negatively associated with anti-cancer immunity in diverse solid cancers
Q129589254PO-402 Establishment of human monoclonal anti tumour antibodies with high affinity to CD9 using an in vitro B cell affinity maturation platform
Q129586042PO-403 Discovery of a new potent and mutant-selective EGFR inhibitor that overcomes T790M-mediated resistance in lung cancer
Q129585819PO-403 The tumour suppressor P53 as a guardian of immune tolerance and suppression
Q129588095PO-404 Cisplatin and ruthenium(III) complexes – comparison of cellular response of treated MDA-MB231 breast cells
Q129587954PO-404 Using functional genetic screens to understand cancer immune evasion
Q129587415PO-405 Blockade of endothelial cell glycolysis to improve current immunotherapy
Q129589305PO-405 Repositioning existing drugs as novel therapeutics for high-risk paediatric leukaemia
Q129587335PO-406 Investigation of the repertoire of peptides bound to MHC class I molecules in tasmanian devil transmissible cancers for the development of a peptide vaccine
Q129588607PO-406 The olive-based oleocanthal as a dual HER2-MET inhibitor for the control of breast cancer
Q129586620PO-407 Identification of unique antigens on prostate cancer stem cells for cytotoxic T cell recognition
Q129589236PO-408 Methanol extract of holothuria scabra inhibits cell growth and induces apoptosis in T47D breast cancer cells
Q129588169PO-408 New targets for the immunotherapy of adult B-cell acute lymphocytic leukaemia
Q129588739PO-409 Highly specific targeting of human acute myeloid leukaemia (AML) cells using functionalised gold nanoparticles
Q129589465PO-409 Signal peptide of PD-1 inhibits cancer cell growth
Q129589515PO-410 Cytotoxicity and genotoxicity of new gadolinium, iron oxide, cobalt ferrite and graphene oxide nanoparticles on some tumour cell lines in vitro
Q129585922PO-410 Discovery of immunogenic neoantigens for peptide vaccination approaches in murine colorectal cancer
Q129585933PO-411 Combinatorial therapy with immune checkpoint blockade and theranostic tumor-targeted nanoparticles in eradication of tumours
Q129589060PO-412 Effectiveness and safety of anti-PD1 (Nivolumab) as second line treatment of advanced non-small cell lung cancer (NSCLC) elderly and heavy smokers patients (PTS) with unknown PD-1 status
Q129585884PO-412 Novel drug discovery approaches for cancer with the inspiration of a natural product – methyl jasmonate
Q129588742PO-413 Estimation of antitumor activity of amino derivatives of quinoxaline-2-carbonitrile 1,4-dioxide
Q129589326PO-413 Immune modulating properties of cyclophosphamide synergise with immunotherapy in preclinical models of neuroblastoma
Q129588221PO-414 Evaluation and comparison of drug loaded composite nano-emulsions’ cellular uptake in malignant melanoma cell line
Q129586149PO-414 Stage IV melanoma patients with tumoural MHC class i loss only respond to anti-PD-1 therapy in the presence of high NK cell density
Q129586005PO-415 Multivalent polymeric nanoparticles as an innovative cancer immunotherapy for colorectal cancer
Q129586854PO-415 New anti-migratory and anti-invasive effects of a fascin inhibitor on colorrectal cancer cells
Q129588548PO-416 A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma
Q129587448PO-416 Cytotoxicity of Ru (II) and Ru (III) salen complexes against breast and colorectal cancer cell lines
Q129588586PO-417 Anti-tumoural effects of IL-15 and CD40 stimulation as a novel combination immunotherapy for pancreatic cancer
Q129586721PO-417 Synthesis of CU(II) complexes derived from imidazole and cytotoxic activity evaluation against breast and colorectal cancers
Q129585893PO-418 Targeting heat shock protein 70 (HSP70) in melanoma with functionalized theranostic superparamagnetic iron oxide nanoparticles
Q129586213PO-419 Poly(I:C) prepares glioblastoma cells for anti-PD-L1 therapy via lymphocyte attraction and activation in a TLR3-dependent manner
Q129586670PO-419 Use of origanum majorana oil in lung cancer therapy
Q129588143PO-420 Harnessing chitosan/Poly(Y)-glutamic acid nanoparticles for immunomodulation at the tumour microenvironment
Q129587453PO-420 Mechanisms of action of anti-proliferative lichen compound protolichesterinic acid
Q129587545PO-421 Anti-CTLA-4 and anti-PD-1 immunotherapies repress tumour progression through independent cellular mechanisms
Q129586015PO-422 Development of an ALK lymphoma-derived autophagosomal and dendritic cells vaccine
Q129586976PO-422 Disagregation in biological medium of promising theranostic agents for cancer
Q129586821PO-423 Investigation of combined immune checkpoint blockade in human malignant pleural mesothelioma
Q129588275PO-424 Discovery of a novel small molecule STING agonist as a new cancer immunotherapy
Q129588525PO-424 modulating hexokinase 2 (HK2) as a novel approach to target metabolic immuno-oncology
Q129587983PO-425 Combined administration of anti-IL6 and anti-PD-L1 antibodies prevents ketogenic failure, reduces tumour progression, and increases overall survival in an autochthonous murine pancreatic cancer model
Q129588775PO-425 The effect of bis structured schiff base material on apoptosis, cytotoxicity and DNA damage of breast cancer cell line
Q123349038PO-426 Gender disparity in lung adenocarcinoma susceptibility in experimental mice model
Q129586811PO-426 Targeting of VEGFR2-expressing cells by chimeric antigen receptor (CAR) T cells for solid tumour therapy
Q129585731PO-427 A nuclear-directed human pancreatic ribonuclease variant is cytotoxic for breast cancer cells cultured in 3D and kills cancer stem cells
Q129586087PO-427 Establishment of KRAS (G12D)/Trp53 null/Pdx1-cre (KPC) mouse homograft tumour models to facilitate preclinical efficacy evaluation of combinatory immunotherapies
Q129587254PO-428 Radiotherapy, immunocytokines and immune checkpoint inhibitors: finding the optimal combination
Q129586209PO-428 Therapeutic potential of nanoparticle encapsulated Wnt and YAP inhibitors using patient derived xenograft models for the treatment of triple negative breast cancer
Q129586887PO-429 Elastin-like recombinamers nanoparticles: an effective drug delivery system on colorectal cancer cells
Q129587217PO-429 Identification of the right immunostimulatory chemotherapeutic partner for anti-CD70 immunotherapy in non-small cell lung cancer
Q129589074PO-430 Natural killer cell-based adoptive immunotherapy is effective in the eradication of chemoresistant stem-like cells in bladder cancer
Q129588595PO-431 A novel strategy to treat advanced, late-stage tumours with real-time tumour vaccination
Q129585714PO-432 New combined nanoparticle therapy inhibits metastatic breast tumour growth with superior efficacy and lower side effect profile to docetaxel
Q129587244PO-432 Small molecules, peptides and antibodies – the comparison of PD-1/PD-L1 blocking potential in an in vitro immune checkpoint blockade assay
Q129586596PO-433 Prognostic relevance of PP1 in breast cancer
Q129586805PO-433 The modulation of redox homeostasis and induction of ferroptotic cell death in hepatocellular carcinoma as an anticancer strategy
Q129589152PO-434 AT1413 antibody derived from a cured AML patient recognisesa unique sialylated CD43 epitope shared by AML, MDS and melanoma cells
Q129588510PO-434 Patient-derived cancer explants preserve tumour architecture and heterogeneity in dynamic culture
Q129586159PO-435 Photoactivation of nanoparticles delivered by mesenchymal stem cells induces osteosarcoma cell death in in vitro 3D co-culture models
Q129585928PO-435 Proteomic classification of triple negative breast cancers
Q129588490PO-436 Dose-dependent relationship between metformin and the occurrence of colorectal cancer among taiwanese patients with type 2 diabetes
Q129587445PO-436 Retargeting T-cell cytotoxicity to a unique sialylated epitope on CD43 expressed by acute myeloid leukaemia
Q129586581PO-437 Drug and radio sensitivity profile of a primary CTC cell line derived from a patient with metastatic neuroendocrine tumour of the distal oesophagus
Q129588012PO-437 Ultrasound-triggered delivery of halogenated pyruvate analogues to breast cancer cells
Q114978886PO-438 Hyperthermia as neoadjuvant treatment for pancreatic tumours in murine models
Q129587267PO-438 Internalisation of cell-penetrating peptides based on CONNEXIN43 in glioma stem cells and neural cells
Q129585992PO-439 Enhanced cytotoxic and chemosensitizing effects of conjugated small gold nanoparticles
Q129588682PO-439 Establishment and characterisation of prostate cancer patient-derived organoids and cells
Q129589116PO-440 Development and characterisation of pre-clinical in vitro/in vivo models from disseminated tumour cells of melanoma patients
Q129587148PO-440 Targeting of triple negative breast tumours using liposomes as drug delivery systems for siRNA and HSP90 inhibitor
Q129586151PO-441 Characterisation of 3D patient-derived xenograft tumour microtissues for in vitro oncology drug development
Q129588147PO-441 Investigation of YAP biological relevance in medulloblastoma SHH TP53 mutated
Q129589077PO-442 Ex vivo prostate cancer culture system recapitulates in vivo response to androgen antagonist
Q129589412PO-442 In vitro assessment of sonic hedgehog (SHH) pathway inhibitior, LDE225, in paediatric ependymoma rela subgroup shows antiproliferative and proapoptotic effects
Q129589231PO-443 In vitro clinical trial for pancreatic cancer patients
Q129588758PO-444 Evaluation of novel nucleoside analogues for lung cancer treatment: an approach based on metronomic chemotherapy
Q129586516PO-444 The emerging role of junctional adhesion molecule-A (JAM-A) as a novel drug target in ductal carcinoma in situ (DCIS)
Q129585971PO-445 E7107 treatment results in aberrantly spliced transcripts and protein products of P53 pathway genes
Q110615771PO-445 The phenotypic plasticity of castration-resistant prostate cancer: from challenge to opportunity
Q129586610PO-446 Anti-tumour efficiency of 20A, a novel G-quadruplex ligand, in in vitro and in vivocancer models: ATM and autophagy interplay
Q129589297PO-446 Targeting co-regulators of hormone-receptors as a novel therapeutic approach for prostate and breast cancer
Q129588612PO-447 CDK5 as a prognostic and predictive factor in colorectal cancer patients
Q129587553PO-448 The AP-1 trancriptional complex regulates AXL-induced resistance to PI3K pathway inhibition in head and neck and esophageal cancer
Q129587569PO-449 Optimisation of an AlphaLISA assay for the characterisation of PROTAC-induced ternary complexes within cell lysates
Q129588195PO-450 Interplay between coding and non-coding genome in human parathyroid tumours
Q129588768PO-450 MEK inhibition synergizes with MDM2 inhibitors through DUSP6 suppression
Q129588687PO-451 Novel combination of tanshinone I and dexamethasone induces apoptosis in myeloma cells by modulating ERK/p38/JNK/NF-kB signalling pathway
Q129586569PO-451 Targeted proteomics to improve therapy stratification of cancer patients
Q129586224PO-452 Selective CD47 immune checkpoint blockade on tumour cells with bispecific antibodies to effectively control tumour growth: primary role of the phagocytes
Q129586542PO-453 Effect of GLP-1 on proliferation and migration in pheochromocytoma and colorectal cancer cells
Q129587530PO-454 Biological activities of novel brassinosteroid analogues in breast cancer cells
Q129588168PO-455 Epigenetic insights: resminostat regulates targets associated with the pathogenesis of cutaneous T cell lymphoma (CTCL)
Q129586771PO-456 Cell line panel profiling of all clinically approved kinase inhibitors for cancer treatment
Q129587384PO-456 Prognostic significance of protein and gene expression of C-MYC, BCL-2, BCL-6 in diffuse large B-cell lymphoma determined by digital image analysis
Q129585561PO-457 Is 8-azaguanine selectively active against aneuploid acute myeloid leukaemia?
Q129588669PO-457 Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers
Q129586141PO-458 A multicenter study to assess EGFR mutational status in plasma: focus on an optimisedworkflow for liquid biopsy in a clinical setting
Q129587963PO-458 The role of functional groups in the antitumor properties of antrafuran
Q129587941PO-459 Systemic anti-inflammatory effect of a new anticancer cyclic peptide ALOS4
Q129588727PO-459 Unravelling endoglin as a potential therapeutic target for the treatment of uveal melanoma
Q129589312PO-460 Gene expression-based probabilistic graphical models identify three independent biological layers in colorrectal cancer
Q129586254PO-460 Targeting endoplasmic reticulum stress using thiosemicarbazones to suppress cancer progression
Q129588467PO-461 A transcriptomic and molecular approach to uncovering achaete-scute complex homolog 2 (ASCL2) as a potential novel driver gene in breast cancer
Q129586228PO-461 Mitochondria-mediated anticancer effect of diphenyleneiodonium chloride (DPI) in aggressive neuroblastoma is regulated by MYCN
Q129589331PO-462 Functional ex vivo assay reveals homologous recombination deficiency in breast cancer beyond BRCA gene defects
Q129586164PO-462 Investigating the potential anti-cancer properties of a novel src family kinase inhibitor in triple negative breast cancer
Q129588652PO-463 Augmentation of NAD+BY NQO1 activation attenuates cisplatin-mediated hearing impairment
Q129587555PO-463 Multiparametric analysis of lung cancer tissue sections using imaging mass cytometry
Q129589408PO-464 Endoglin-targeted therapy demonstrates strong preclinical anti-tumour activity in ewing sarcoma using antibody-drug conjugates
Q129587281PO-464 Influence of natural DNA-binding compounds with cancer preventive activity on chromatin structure
Q129588606PO-465 Effect of pain management drugs in metastatic prostate cancer: in vitro studies
Q129586783PO-465 N-glycans of pseudomyxoma peritonei present highly increased fucosylation and multifucosylation correlates with high-grade morphology
Q129586624PO-466 PI3K-C2A regulates mitotic spindle assembly and chemotherapy response in breast cancer
Q129586000PO-467 Integrative modelling to understand and predict cancer drug response
Q129587559PO-467 Unclarified cases of microsatellite instability analyses for lynch syndrome diagnostics
Q129585889PO-469 Role of promoter hypermethylation of hocT1 gene (SLC22A1) in response to imatinib of chronic myeloid leukaemia patients
Q129588198PO-470 hOCT1 gene polymorphism M420del is associated with decreased response to imatinib in CML patients and amp; its effect is counteracted by M408V polymorphism
Q129586639PO-471 Circular RNA detection in melanoma patients’ plasma
Q129587391PO-471 Exosomes and transferring of hormonal resistance of breast cancer cells
Q129585828PO-472 Chemotherapy resistance-associated epithelial to endothelial transition in gastric cancer
Q129586644PO-472 MicroRNA as biomarkers of resistance to regorafenib in metastatic colorectal cancer patient
Q129588710PO-473 Quantification of ERCC1-XPF complexes in ovarian cancer xenografts with different sensitivity to cisplatin
Q129589386PO-473 WNT6 expression in glioblastoma: mechanistic, functional and clinical implications
Q129586844PO-475 Unravelling the role of sialylation in targeted therapy resistance using 3D cancer models
Q129587263PO-476 Correlation between circulating tumour DNA and progression-free survival and tumour burden in initial diagnosis of advanced-stage non-small cell lung cancer
Q129585941PO-476 Increased ERK phosphorylation as a candidate driver of resistance to the experimental cancer drug AT13148
Q129587308PO-477 A novel role for nanog as an early cancer risk marker in patients with laryngeal precancerous lesions
Q129589168PO-477 BCL-Xl inhibition enhances dinaciclib-induced cell death in soft-tissue sarcoma cell lines
Q129588132PO-478 Chemosensitization of cisplatin-resistant testicular germ cell tumours cells
Q129587149PO-478 Prognostic significance of E-cadherin and beta-catenin expression in HPV-negative oropharyngeal squamous cell carcinomas
Q129586274PO-479 Development and characterisation of everolimus resistant breast cancer cells
Q129588114PO-479 NUB1 as a prognostic marker in breast cancer: a retrospective, integrated genomic, transcriptomic, and protein analysis
Q129587623PO-481 Alteration in epigenetic-related genes and histones modifications levels revealed as a potential resistance factor to oxaliplatin in colorectal cancer cells
Q129586858PO-481 Patient-derived sarcoma primary cell lines with preserved cancer stem cell properties to screen anticancer compounds
Q129589282PO-482 Analysis of small RNA cargo in urinary and plasma EVs and matching prostate cancer and normal prostate tissues
Q129585943PO-482 Efficacy of inhibition of BAD Ser99 phosphorylation by a novel small molecule in cisplatin resistant ovarian cancer
Q129586905PO-483 Improved sensitivity for non-invasive diagnosis of high-grade serous ovarian cancer
Q129589099PO-483 Phenotype switching as an escape mechanism to targeted therapies in melanoma
Q129588829PO-484 Development of a two-step screening-and-confirmation approach to efficiently identify synergistic drug combinations with the PARP inhibitor niraparib
Q129588511PO-484 Immunohistochemical analysis of mTORC1 and mTORC2-related proteins in renal cell carcinoma of kidney transplant recipients
Q129586250PO-485 Ferroptosis is the nexus for zero-valent iron-based highly selective anticancer nanotherapy and anti-nanoresistance
Q129586575PO-485 Low abundance circulating proteins in giant cell tumours of bone
Q129588190PO-486 Surrogate biomarkers of clinical efficacy in stage IIIB/IV non-small-cell lung cancer patients treated with an optimised EGF-based vaccination schedule
Q129587364PO-487 Cellular glycosylation affects trastuzumab binding and sensitivity of breast cancer cells to doxorubicin and growth factors
Q129589153PO-487 Prognosis of triple negative breast cancer is associated with MHC II genes
Q129589085PO-488 AGR2 is a progression marker and a potential therapeutic target in non-muscle invasive bladder cancer
Q129587408PO-488 Activation of Wnt signalling in temozolomide (TMZ) treated glioma cells: mechanism and implications in TMZ chemoresistance
Q129589363PO-489 TP53 mutations and focal genomic amplifications for ctDNA detection in high-grade serous ovarian carcinoma
Q129585734PO-489 Tumour-specific oncogenic signalling activities define sensitivity to combinatorial MEK inhibition and stratify Kras-driven lung cancer
Q129587283PO-490 Expression of cortactin and focal adhesion kinase in early stages of laryngeal tumorigenesis and clinical application for cancer risk-stratification
Q129588774PO-491 Frequent mTORC1 activation in head and neck squamous cell carcinomas correlates with favourable clinical outcome
Q129587215PO-491 Single-cell phenotypic profiling of breast cancerpatient-derived tumour xenografts using mass cytometry
Q129588589PO-492 Establishment of new drug-resistant gastric cancer cell lines
Q129587144PO-492 Ex vivo functional homologous recombination (HR) test detects BRCA reversal and resistance to PARPi in metastatic breast cancer patients
Q129589232PO-493 Targeting the drug resistance epigenetic driver SMYD3 as a new strategy to potentiate chemotherapeutic effects
Q129589228PO-493 ctDNA profiles of metastatic melanoma patients under therapy
Q129589267PO-494 A pathogenic network of novel molecular mechanisms driving merkel cell carcinomas. shared oncogenic pathways between virus-positive and UV-induced tumours
Q129586537PO-494 Using functional genetic screens to understand resistance to PARPi in BRCA-deficient tumours
Q129587526PO-495 PI3K pathway upregulation mediates acquired resistance to platinum agents and polyadenoribose polymerase inhibitors (PARPi) in BRCA1-methylated ovarian cancer (OC)
Q129585964PO-495 Prediction of chemotherapy sensitivity on ascites of ovarian cancer patients
Q129587125PO-496 Integrated OMICS- based approach to the identification of specific expression profiles associated with PTEN-loss
Q129585858PO-496 Loss of PARG drives PARP inhibitor resistance in BRCA2-deficient mouse mammary tumours
Q129587440PO-497 Microtubule regulatory proteins as predictive biomarkers of taxane-based chemoresistance in breast cancer?
Q129588779PO-498 Quantifying the dynamics of acquired treatment resistance and evolutionary herding for the prediction of collateral sensitivity in cancer model systems
Q129586399PO-498 Spliced RNA panels from tumor-educated platelets (TEP) enable detection of early breast cancer
Q129585948PO-499 Comparison of expression of miR21’s guide strand (5P) and passenger strand (3P) in breast tumour progression
Q129586820PO-500 A novel role for junctional adhesion molecule-a (JAM-A) in HER2-positive gastro-oesophageal cancers
Q129585878PO-500 NRF2 represents a convergent point of acquired resistance in HER2 positive gastric cancer models
Q129588842PO-501 Deconstructing the role of CD44 in gastric cancer resistance to cisplatin
Q129586210PO-501 Loss of SOX9 expression is a predictive marker of relapse in gastric cancer
Q129588625PO-502 A potential role for HSP90 in HER2-driven breast cancer (BC)
Q129589157PO-503 HDAC inhibitor resistance in colorectal cancer: RAS and AMP; MYC – the partners in crime
Q129585851PO-503 The cohesin stromal antigen 1 (SA-1) modulates colonic and colorectal cancer (CRC) stem cells: mechanism for racial disparities
Q129589308PO-504 EXPEL: a novel non-destructive method for mining soluble tumour biomarkers
Q129586003PO-504 The impact of KRAS mutations on the cytotoxic effects of afatinib and allitinib in non-small cell lung cancer cell line
Q129588752PO-505 Prognostic impact of KRAS splicing in microsatellite stable colorectal cancer
Q129588496PO-505 Targeting PIM kinase to overcome resistance to PI3K-mTOR inhibition in NSCLC
Q129587587PO-506 Targeting membrane-bound Hsp70 on cancer cells with functionalized superparamagnetic nanoparticles: new perspectives for early diagnosis and therapy
Q129587374PO-506 The dynamics of HER2 status in esophageal adenocarcinoma
Q129586564PO-507 ADAM22 as a therapeutic target for endocrine resistant metastatic breast cancer
Q129587536PO-507 Deregulated mechanisms downstream of PLCG1 promoting cutaneous T cell lymphomaprogression
Q129588543PO-508 A novel predictor for stratifying pancreatic cancer patients to DNA damage checkpoint inhibitors
Q129588554PO-508 Detection and role of novel fusion oncogenes in paediatric cancers
Q129588681PO-509 CD44V6 is a marker of poor prognosis and has potential as predictive marker of response to conventional chemotherapy in gastric cancer
Q129586846PO-509 Novel molecular classification of muscle-invasive bladder cancer opens new treatment opportunities
Q129585237PO-510 Investigation of potential therapeutic targets by using in silico methods in glioblastoma
Q129585974PO-510 XRCC6BP1: a novel role in the DNA repair of platinum resistant NSCLC cells
Q129586598PO-511 High miR-9 levels represent a novel prognostic biomarker to predict development of malignant meningioma
Q129585904PO-511 Somatic and germline calls from tumour/normal whole genome data: bioinformatics workflow for reproducible research
Q129586090PO-512 Gene expression signature comprising distinct stromal and tumor-intrinsic signals predicts response to combined anti-PD1 and anti-CTLA4 checkpoint inhibition
Q129589160PO-512 Protein markers of progression risk in patients with squamous cell vulvar carcinoma
Q129587493PO-513 Using MAPK and PI3K signalling to predict patient outcome in resectable stage IIIB/C melanoma patients neoadjuvantly treated with dafrafenib and trameitinib
Q129587490PO-514 Can ketamine be an optimal anaesthetic drug for cancer resection? a randomisedcontrolled clinical trial
Q129587575PO-514 High-throughput drug screening to identify therapies reversing aberrant cell differentiation in AML
Q129585817PO-515 Transcriptome analysis identified alcam expression as potential biomarker to LSCC patient’s outcome
Q129588838PO-516 E6/E7 RNA(LIP): a novel liposomal RNA vaccine for treatment of patients with HPV16-positive malignancies
Q129589328PO-516 Genes of infiltrated immune cells are prognosis biomarkers in specific subtypes of colorectal cancer
Q129587949PO-517 Peptide-based diagnostic in vivo targeting of membrane Hsp70 positive tumours
Q129586532PO-517 Protein profiling in colorectal cancer: from biological mapping to functional validation
Q129585725PO-518 Biomarker signature defines a potential therapeutic subclass of triple negative breast cancer
Q129587107PO-518 Localization of prostate cancer metastases– diagnostic value of quantitative PET parameters
Q129587117PO-519 Can PSA level and its change in time predict localization of proastate cancer relapse, assesed by PET-CT with 18F-Choline?
Q129587203PO-519 Combined inhibition of MEK and PI3KCA pathway induces synergic antitumor activity in HER2 amplified colorectal cancer models
Q129588516PO-520 Comprehensive molecular classification of localised prostate adenocarcinoma reveals a tumour subtype predictive of a non-aggressive disease
Q129586155PO-520 POLE gene mutation analysis in colorectal cancer patients with MSS – a pilot study
Q129587220PO-521 Expression of oestrogen receptor beta as a predictive marker of platinum and taxane-based chemotherapy in ovarian cancer patients
Q129587265PO-521 Gene expression-based subtypes of pancreatic ductal adenocarcinoma offer leads for targeted therapy
Q129588675PO-522 Biological layers identified two independent classifications in melanoma tumours
Q129585856PO-522 Global proteome and phosphoprotein profiling of meningiomas reveals novel potential therapeutic targets and biomarkers
Q129588010PO-523 Sensitivity of colorectal cancer (CRC) CRIS subtypes to SMAC mimetic birinapant with standard of care chemotherapeutics: implications for personalised medicine
Q129586640PO-523 Unveiling the microRNA signature of gastric cancer exosomes: longitudinal and cross-sectional perspectives
Q129588154PO-524 MT4-MMP, EGFR and Rb expressions are predictive biomarkers of response to erlotinib-palbociclib combination in TNBC
Q129588016PO-525 Molecular signatures of circulating microRNAs as early breast cancer biomarkers
Q98621905Pain workshop ESMO: Africa (response)
Q55210233Palliative treatment with radiation-emitting metallic stents in unresectable Bismuth type III or IV hilar cholangiocarcinoma.
Q128572435Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with gastric cancer
Q93267193Patient and family support in the era of fake e-medicine: food for thought from an international consensus panel
Q90861362Patient-reported outcomes in a phase II study of alectinib
Q55710220Patient-reported outcomes in a phase II, North American study of alectinib in patients with ALK-positive, crizotinib-resistant, non-small cell lung cancer.
Q55504137Patient-reported pain severity, pain interference and health status in HR+/HER2- advanced/metastatic breast cancer.
Q55287059Patient-reported tolerability of adverse events in phase 1 trials.
Q113874541Patterns of care and outcomes of 417 patients with METAstatic SYNovial sarcoma (METASYN): real-life data from the French Sarcoma Group (FSG)
Q55142588Pembrolizumab as second-line therapy in non-small cell lung cancer in northern Norway: budget impact and expected gain-a model-based analysis.
Q55117001Pemetrexed-cisplatin with concurrent thoracic radiation after pemetrexed-cisplatin induction in patients with unresectable locally advanced non-squamous NSCLC: results by age subgroup.
Q54956905Peritumoural ground-glass opacity associated with tumour pseudoprogression in a patient with non-small cell lung cancer treated with nivolumab.
Q100315741Pertuzumab and trastuzumab emtansine in patients with HER2-amplified metastatic colorectal cancer: the phase II HERACLES-B trial
Q64062066Phase I clinical trial of decitabine (5-aza-2'-deoxycytidine) administered by hepatic arterial infusion in patients with unresectable liver-predominant metastases
Q90299705Phase I study of TrasGEX, a glyco-optimised anti-HER2 monoclonal antibody, in patients with HER2-positive solid tumours
Q55005321Phase I study of neoadjuvant chemotherapy with S-1 and oxaliplatin for locally advanced gastric cancer (Neo G-SOX PI).
Q128681931Phase I study of peposertib and avelumab with or without palliative radiotherapy in patients with advanced solid tumors
Q55111944Phase I study of the investigational oral mTORC1/2 inhibitor sapanisertib (TAK-228): tolerability and food effects of a milled formulation in patients with advanced solid tumours.
Q55224235Phase I study of tomuzotuximab, a glycoengineered therapeutic antibody against the epidermal growth factor receptor, in patients with advanced carcinomas.
Q90861343Phase I, open-label study of pasireotide in patients with BRAF-wild type and NRAS-wild type, unresectable and/or metastatic melanoma
Q97528413Phase I, open-label, multicentre study of buparlisib in combination with temozolomide or with concomitant radiation therapy and temozolomide in patients with newly diagnosed glioblastoma
Q103825789Phase I/IIa, open-label, multicentre study to evaluate the optimal dosing and safety of ODM-203 in patients with advanced or metastatic solid tumours
Q90861349Phase II study assessing the benefit of cisplatin re-introduction (stop-and-go strategy) in patients with advanced non-squamous non-small cell lung cancer: the IFCT-1102 BUCiL study (a Better Use of Cisplatin in Lung cancer)
Q104745965Phase II study of eribulin in combination with gemcitabine for the treatment of patients with locally advanced or metastatic triple negative breast cancer (ERIGE trial). Clinical and pharmacogenetic results on behalf of the Gruppo Oncologico Italian
Q54162899Phase II study of erlotinib plus tivantinib (ARQ 197) in patients with locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer just after progression on EGFR-TKI, gefitinib or erlotinib.
Q98575130Phase II study of lenvatinib for metastatic colorectal cancer refractory to standard chemotherapy: the LEMON study (NCCH1503)
Q101241759Phase II trial of ribociclib and letrozole in patients with relapsed oestrogen receptor-positive ovarian or endometrial cancers
Q54990179Phase III study of gefitinib or pemetrexed with carboplatin in EGFR-mutated advanced lung adenocarcinoma.
Q55264112Phase Ib/II trial evaluating the safety, tolerability and immunological activity of durvalumab (MEDI4736) (anti-PD-L1) plus tremelimumab (anti-CTLA-4) combined with FOLFOX in patients with metastatic colorectal cancer.
Q129588555Po-212 CEP55 over-expression causes genomic instability to initiate spontaneous tumour formation in vivo
Q129586630Po-309 Characterisation of the immune microenvironment of colorectal cancer using a novel high-plex protein analysis technology
Q129586861Po-323 In vivo monitoring of tumour responses to chemotherapy using multiparameter fluorescence imaging
Q129585794Po-327 Modelling intratumor heterogeneity through CRISPR-barcodes
Q98646963Positive tumour CD47 expression is an independent prognostic factor for recurrence in resected non-small cell lung cancer
Q90299673Postoperative chemotherapy with single-agent fluoropyrimidines after resection of colorectal cancer liver metastases: a meta-analysis of randomised trials
Q55715397Potential new biomarkers for squamous carcinoma of the uterine cervix.
Q55249373Practical issues of biomarker-assisted targeted therapy in precision medicine and immuno-oncology era.
Q117042566Precision oncology for BRAF-mutant cancers with BRAF and MEK inhibitors: from melanoma to tissue-agnostic therapy
Q90050880Precision oncology in urothelial cancer
Q58698377Precision oncology: separating the wheat from the chaff
Q102219893Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer
Q28067482Predictive and prognostic biomarkers of targeted agents and modern immunotherapy in renal cell carcinoma
Q64998084Predictive value of improvement in the immune tumour microenvironment in patients with breast cancer treated with neoadjuvant chemotherapy.
Q92091033Preferences to receive unsolicited findings of germline genome sequencing in a large population of patients with cancer
Q58762727Preparing for the incoming wave of biosimilars in oncology
Q96639488Prescreening for COVID-19 in patients receiving cancer treatment using a patient-reported outcome platform
Q129437483Prevalence and factors associated with professional burnout in Polish oncologists—results of a nationwide survey
Q102210210Prevalence and prognostic impact of comorbidities and peripheral blood indices in sarcomas
Q55229726Prevalence of hypothyroidism among patients with breast cancer treated with radiation to the supraclavicular field: a single-centre survey.
Q102335573Prevention of venous thromboembolism in ambulatory patients with cancer
Q91673681Prognosis of early stage small cell bladder cancer is not always dismal
Q58694195Prognostic Nutritional Index as an independent prognostic factor in locoregionally advanced squamous cell head and neck cancer
Q58698384Prognostic Nutritional Index: an easy nutritional screening for patients with head and neck cancer?
Q100453954Prognostic factors in phyllodes tumours of the breast: retrospective study on 166 consecutive cases
Q94947942Prognostic impact of indoleamine 2,3-dioxygenase 1 (IDO1) mRNA expression on circulating tumour cells of patients with head and neck squamous cell carcinoma
Q64997225Prognostic implications of mismatch repair deficiency in patients with nonmetastatic colorectal and endometrial cancer.
Q55267388Prognostic indices of inflammatory markers, cognitive function and fatigue for survival in patients with localised colorectal cancer.
Q104745954Prognostic model for risk stratification of de novo metastatic nasopharyngeal carcinoma patients treated with chemotherapy followed by locoregional radiotherapy
Q91610309Prognostic nomogram based on the metastatic lymph node ratio for gastric neuroendocrine tumour: SEER database analysis
Q101381663Prognostic role of distant disease-free interval from completion of adjuvant trastuzumab in HER2-positive early breast cancer: analysis from the ALTTO (BIG 2-06) trial
Q112646265Prognostic role of serum thymidine kinase 1 kinetics during neoadjuvant chemotherapy for early breast cancer
Q64990242Prospective analysis of 895 patients on a UK Genomics Review Board.
Q89553736Proxies of quality of life in metastatic colorectal cancer: analyses in the RECOURSE trial
Q55319545QTWiST analysis of the RECOURSE trial of trifluridine/tipiracil in metastatic colorectal cancer.
Q54889286Quality of life during first-line FOLFOX4±panitumumab in RAS wild-type metastatic colorectal carcinoma: results from a randomised controlled trial.
Q54947491Quality to rely on: meeting report of the 5th Meeting of External Quality Assessment, Naples 2016.
Q90299720Questions asked in the everyday practice: immune checkpoint inhibitors
Q91968493Radiation therapy during the coronavirus disease 2019 (covid-19) pandemic in Italy: a view of the nation's young oncologists
Q54002435Radiological imaging markers predicting clinical outcome in patients with metastatic colorectal carcinoma treated with regorafenib: post hoc analysis of the CORRECT phase III trial (RadioCORRECT study).
Q28079904Radiological staging in pregnant patients with cancer
Q98574898Ramucirumab in the second-line for patients with hepatocellular carcinoma and elevated alpha-fetoprotein: patient-reported outcomes across two randomised clinical trials
Q91673708Rationale and design of the BRAVERY study (EPOC1701): a multicentre phase II study of eribulin in patients with BRAF V600E mutant metastatic colorectal cancer
Q89807855Rationale and design of the POLEM trial: avelumab plus fluoropyrimidine-based chemotherapy as adjuvant treatment for stage III mismatch repair deficient or POLE exonuclease domain mutant colon cancer: a phase III randomised study
Q58773448Rationale and design of the TRUSTY study: a randomised, multicentre, open-label phase II/III study of trifluridine/tipiracil plus bevacizumab versus irinotecan, fluoropyrimidine plus bevacizumab as second-line treatment in patients with metastatic co
Q125634553Rationale and study design of the CHIPPI-1808 trial: a phase III randomized clinical trial evaluating hyperthermic intraperitoneal chemotherapy (HIPEC) for stage III ovarian cancer patients treated with primary or interval cytoreductive surgery
Q90711337Rationale of the rare cancer list: a consensus paper from the Joint Action on Rare Cancers (JARC) of the European Union (EU)
Q112708465Real-world circulating tumor DNA analysis depicts resistance mechanism and clonal evolution in ALK inhibitor-treated lung adenocarcinoma patients
Q98574871Real-world clinical outcome and toxicity data and economic aspects in patients with advanced breast cancer treated with cyclin-dependent kinase 4/6 (CDK4/6) inhibitors combined with endocrine therapy: the experience of the Hellenic Cooperative Oncol
Q101225154Real-world clinical outcomes of first-generation and second-generation epidermal growth factor receptor tyrosine kinase inhibitors in a large cohort of European non-small-cell lung cancer patients
Q117042572Real-world data in oncology: a questionnaire-based analysis of the academic research landscape examining the policies and experiences of the cancer cooperative groups
Q64966446Real-world features associated with cancer-related venous thromboembolic events.
Q55425909Recent advances in adjuvant therapy for patients with melanoma.
Q54962187Recent advances in the biology and treatment of brain metastases of non-small cell lung cancer: summary of a multidisciplinary roundtable discussion.
Q28070120Recent advances in the biology of human circulating tumour cells and metastasis
Q28072755Recent developments and translational aspects in targeted therapy for metastatic breast cancer
Q97528401Rechallenge of denosumab in jaw osteonecrosis of patients with unresectable giant cell tumour of bone: a case series analysis and literature review
Q112825265Recommendations for a practical implementation of circulating tumor DNA mutation testing in metastatic non-small-cell lung cancer
Q94947943Recurrent squamous cell carcinoma of the perianal skin: a case report
Q54998380Reduction in nephrotoxicities using short hydration for chemotherapy containing cisplatin: a consecutive analysis of 467 patients with thoracic malignancies.
Q55380623Relevance of a molecular tumour board (MTB) for patients' enrolment in clinical trials: experience of the Institut Curie.
Q28079168Renal insufficiency and cancer treatments
Q54963659Reply to 'Biosimilars: a position paper of the European Society for Medical Oncology, with particular reference to oncology prescribers'.
Q94684161Reply to Authors
Q54001082Reply to Early colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Q59133674Report from the ESMO 2018 presidential symposium-Radiotherapy to the primary tumour for men with newly diagnosed metastatic prostate cancer: survival results from STAMPEDE
Q57071162Report on the status of women occupying leadership roles in oncology
Q98196262Response assessment and outcome of combining immunotherapy and radiosurgery for brain metastasis from malignant melanoma
Q55316420Response: Concerns with conclusions in the article by Sherwood et al 'Key differences between 13 KRAS mutation detection technologies and their relevance for clinical practice'.
Q55182736Response: Effects of physical activity on depressive symptoms during breast cancer survivorship: a meta-analysis of randomised control trials.
Q100958293Responsiveness to immune checkpoint inhibitors versus other systemic therapies in RET-aberrant malignancies
Q54097440Results of the safety run-in part of the METAL (METformin in Advanced Lung cancer) study: a multicentre, open-label phase I-II study of metformin with erlotinib in second-line therapy of patients with stage IV non-small-cell lung cancer.
Q54977835Retrospective analysis of HER2 therapy interruption in patients responding to the treatment in metastatic HER2+ breast cancer.
Q99571851Retrospective analysis of the prevalence of specialised palliative care services for patients with metastatic breast cancer
Q55002911Retrospective review of metastatic melanoma patients with leptomeningeal disease treated with intrathecal interleukin-2.
Q28076777Review of hormone-based treatments in postmenopausal patients with advanced breast cancer focusing on aromatase inhibitors and fulvestrant
Q55118995Ribociclib: a valuable addition to treatment options in breast cancer?
Q58694213Risk factors for the development of brain metastases in patients with HER2-positive breast cancer
Q55233903Rituximab biosimilars open new horizons in immunotherapy.
Q55399016Role of chemotherapy in resectable liver metastases from colorectal cancer: food for thought from pooled evidence.
Q55318920S-1 and oxaliplatin (SOX) plus bevacizumab versus mFOLFOX6 plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer: updated overall survival analyses of the open-label, non-inferiority, randomised phase III: SOFT stud
Q98906099SARS-CoV-2 seroprevalence in oncology healthcare professionals and patients with cancer at a tertiary care centre during the COVID-19 pandemic
Q129588822SPOT-001 Molecular and biophysical determinants of chromosomal translocations: a multiomics approach
Q129589404SPOT-002 Caspase-3 regulates YAP-dependent organ size and tumour development
Q129588155SPOT-003 Thymidylate synthase maintains the undifferentiated state of aggressive breast cancers
Q129588104SPOT-004 NEDD9 is crucial for tumour progression in renal cell carcinoma mouse models
Q129587991SPOT-006 Stem cell-associated heterogeneity in glioblastoma is a result of intrinsic tumour plasticity shaped by the microenvironment
Q129587160SPOT-007 Identifying novel combinatorial synthetic lethal vulnerabilities in KRAS-driven lung cancer
Q129589268SPOT-008 Neurotensin receptor type 2 protects B-cell chronic lymphocytic leukaemia cells from apoptosis
Q129589237SPOT-009 Identification of novel hippo pathway regulators using a genome wide CRISPR screen
Q129587103SPOT-011 Studying the implication of the RAS/MAPK and PI3K/AKT/TOR pathways in prostate cancer through an in vivo model of drosophila accessory glands tumorigenesis
Q129586752SPOT-012 Large-scale CRISPR screening to identify actionable cancer drug targets
Q92091040STK11 and KEAP1 mutations as prognostic biomarkers in an observational real-world lung adenocarcinoma cohort
Q55283312Safeguarding the future of independent, academic clinical cancer research in Europe for the benefit of patients.
Q55065627Safety and activity of IT-139, a ruthenium-based compound, in patients with advanced solid tumours: a first-in-human, open-label, dose-escalation phase I study with expansion cohort.
Q55266511Safety and efficacy of intra-arterial hepatic chemotherapy with doxorubicin-loaded nanoparticles in hepatocellular carcinoma.
Q92684900Safety and efficacy of naldemedine in cancer patients with opioid-induced constipation: a pooled, subgroup analysis of two randomised controlled studies
Q55025685Safety and immunogenicity of MAGE-A3 cancer immunotherapeutic with dacarbazine in patients with MAGE-A3-positive metastatic cutaneous melanoma: an open phase I/II study with a first assessment of a predictive gene signature.
Q54945635Safety and immunogenicity of the PRAME cancer immunotherapeutic in metastatic melanoma: results of a phase I dose escalation study.
Q55073748Safety data from the phase III Japanese ACHIEVE trial: part of an international, prospective, planned pooled analysis of six phase III trials comparing 3 versus 6 months of oxaliplatin-based adjuvant chemotherapy for stage III colon cancer.
Q96124448Safety, efficacy and patient-reported outcomes with trifluridine/tipiracil in pretreated metastatic colorectal cancer: results of the PRECONNECT study
Q90437259Safety, tolerability and clinical implementation of 'ready-to-use' 68gallium-DOTA0-Tyr3-octreotide (68Ga-DOTATOC) (SomaKIT TOC) for injection in patients diagnosed with gastroenteropancreatic neuroendocrine tumours (GEP-NETs)
Q54918484Scoring of PD-L1 expression intensity on pulmonary adenocarcinomas and the correlations with clinicopathological factors.
Q64065064Screening tool for malignant bowel obstruction in relapsed, metastatic ovarian cancer
Q98732999Second-line cabozantinib after sorafenib treatment for advanced hepatocellular carcinoma: a subgroup analysis of the phase 3 CELESTIAL trial
Q54970742Second-line treatments: moving towards an opportunity to improve survival in advanced gastric cancer?
Q55088555Sequential HER2 blockade as effective therapy in chemorefractory, HER2 gene-amplified, RAS wild-type, metastatic colorectal cancer: learning from a clinical case.
Q112289900Serologic response to COVID-19 infection and/or vaccine in cancer patients on active treatment
Q55110249Severe steroid-resistant anti-PD1 T-cell checkpoint inhibitor-induced hepatotoxicity driven by biliary injury.
Q113874537Sex and gender disparities in patients with advanced gastroesophageal adenocarcinoma: data from the AGAMENON-SEOM registry
Q122947065Sex and gender perspectives in colorectal cancer
Q104745951Sex as decisive variable in lymphoid neoplasms-an update
Q99616288Sex differences in cancer chemotherapy effects, and why we need to reconsider BSA-based dosing of chemotherapy
Q102053470Sex-specific and gender-specific aspects in patient-reported outcomes
Q102378117Sex-specific aspects of epidemiology, molecular genetics and outcome: primary brain tumours
Q55262824Shortening adjuvant chemotherapy in stage III colon cancer: are we ready for a change?
Q55153362Single institution long-term efficacy and safety analysis of abiraterone acetate (AA) in the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) in a named patient programme (NPP).
Q55309832Single-agent PARP inhibitors for the treatment of patients with BRCA-mutated HER2-negative metastatic breast cancer: a systematic review and meta-analysis.
Q91785334Single-institute comparison of the efficacy of systemic chemotherapy for oesophagogastric junction adenocarcinoma and stomach adenocarscinoma in a metastatic setting
Q102053464Soluble PD-L1 is associated with local and systemic inflammation markers in primary and secondary brain tumours
Q58762789Somatic cancer genetics in the UK: real-world data from phase I of the Cancer Research UK Stratified Medicine Programme
Q54969586Specific CDK4/6 inhibition in breast cancer: a systematic review of current clinical evidence.
Q91047160Stereotactic body radiation therapy in combination with systemic therapy for metastatic renal cell carcinoma: a prospective multicentre study
Q54989107Successful osimertinib treatment for leptomeningeal carcinomatosis from lung adenocarcinoma with the T790M mutation of EGFR.
Q97528427Supplemental parenteral nutrition: decisions based on weak evidence
Q54937562Surgery of the primary tumour in patients presenting with de novo metastatic breast cancer: to do or not to do?
Q54866500Survey of the management of chemotherapy-induced peripheral neuropathy in Japan: Japanese Society of Medical Oncology.
Q129445979Survival impact of post-operative immunotherapy in resected stage III cutaneous melanomas in the checkpoint era
Q92684921Survival of patients with metastatic HER2 positive gastro-oesophageal cancer treated with second-line chemotherapy plus trastuzumab or ramucirumab after progression on front-line chemotherapy plus trastuzumab
Q92684874Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events
Q55514098Switching from standard to dose-dense chemotherapy in front-line treatment of advanced ovarian cancer: a retrospective study of feasibility and efficacy.
Q97535476Systemic chemotherapy for gastro-oesophagogastric junction adenocarcinoma and stomach adenocarcinoma in a metastatic setting
Q55389129TAS-102 and the quest for predictive biomarkers.
Q54162903TKI-induced pure red cell aplasia: first case report of pure red cell aplasia with both imatinib and nilotinib.
Q55644910TPF induction chemotherapy increases PD-L1 expression in tumour cells and immune cells in head and neck squamous cell carcinoma.
Q56368555TRIPLETE: a randomised phase III study of modified FOLFOXIRI plus panitumumab versus mFOLFOX6 plus panitumumab as initial therapy for patients with unresectable and wild-type metastatic colorectal cancer
Q64284091Targeted therapy in cervical cancer
Q55182988Targeting immune checkpoints in breast cancer: an update of early results.
Q92684929Targeting prognostic proinflammatory biomarkers to improve outcome on IO drugs
Q54305229Teleconsultation ultrasonography: a new weapon to combat cholangiocarcinoma.
Q100761051Tetracyclines increase the survival of NSCLC patients treated with EGFR TKIs: a retrospective nationwide registry study
Q94410807Thank you to our reviewers 2016
Q55344317The 'Charter of Rights for Family Caregivers'. The role and importance of the caregiver: an Italian proposal.
Q113442439The COVID-19 pandemic could be a setback for gender equality in oncology—and a key moment to push ahead with transformative policies
Q100385689The DNA damage repair (DDR) pathway in biliary tract cancer (BTC): a new Pandora's box?
Q55175552The ESMO position paper on biosimilars in oncology: enhancing the provision of accurate education and information.
Q54738129The ESMO/ASCO Global Curriculum and the evolution of medical oncology training in Europe.
Q55412581The European Cancer Patient's Bill of Rights, update and implementation 2016.
Q104745957The European Medicines Agency review of the initial application of atezolizumab and the role of PD-L1 expression as biomarker for checkpoint inhibitors
Q55181578The European Society for Medical Oncology 'Magnitude of Clinical Benefit Scale' field-tested in infrequent tumour entities: an extended analysis of its feasibility at the Medical University of Vienna.
Q55017077The European Society for Medical Oncology Magnitude of Clinical Benefit Scale in daily practice: a single institution, real-life experience at the Medical University of Vienna.
Q55029610The care of adolescents and young adults with cancer: results of the ESMO/SIOPE survey.
Q96639279The clinical and cost-effectiveness of supplemental parenteral nutrition in oncology
Q128460728The combination treatment of oncolytic adenovirus H101 with nivolumab for refractory advanced hepatocellular carcinoma: an open-label, single-arm, pilot study
Q92972140The earlier the better? Apalutamide for non-metastatic castration resistant prostate cancer
Q55058089The effect of adjuvant chemotherapy in male breast cancer: 134 cases from a retrospective study.
Q55397977The hard road to ranking the clinical benefit of antineoplastic agents: ESMO Award 2016 presentation.
Q104745959The impact of the multidisciplinary tumor board (MDTB) on the management of pancreatic diseases in a tertiary referral center
Q129660451The increasing burden of testicular seminomas and non-seminomas in adolescents and young adults (AYAs): incidence, treatment, disease-specific survival and mortality trends in the Netherlands between 1989 and 2019
Q89494899The integrating nutritional therapy in oncology (INTO) project: rationale, structure and preliminary results
Q54980315The promise of immunotherapy in head and neck squamous cell carcinoma: combinatorial immunotherapy approaches.
Q96223278The rationale behind targeting the ICOS-ICOS ligand costimulatory pathway in cancer immunotherapy
Q64102014The role of hormone therapy and chemotherapy in oligometastatic prostate cancer
Q89807845The sarcoma diagnostic interval: a systematic review on length, contributing factors and patient outcomes
Q28071772Therapeutic value of EGFR inhibition in CRC and NSCLC: 15 years of clinical evidence
Q100533130Thirteen-year analyses of medical oncology outpatient day clinic data: a changing field
Q29303933Threat posed by unproven drugs in medical oncology
Q54990183Time since start of first-line therapy as a predictive clinical marker for nintedanib in patients with previously treated non-small cell lung cancer.
Q57298272Tobacco smoking and cessation and PD-L1 inhibitors in non-small cell lung cancer (NSCLC): a review of the literature
Q96431072Tocilizumab for the treatment of paraneoplastic inflammatory syndrome associated with angiomatoid fibrous histiocytoma
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