A prospective trial of midwest breast cancer patients: a p53 gene mutation is the most important predictor of adverse outcome.

scientific article

A prospective trial of midwest breast cancer patients: a p53 gene mutation is the most important predictor of adverse outcome. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/(SICI)1097-0215(20000120)89:1<32::AID-IJC6>3.0.CO;2-G
P698PubMed publication ID10719728

P50authorJulie M. CunninghamQ67440680
P2093author name stringS S Sommer
A Hartmann
L E Wold
H Blaszyk
J S Kovach
D Schaid
P2860cites workNonparametric Estimation from Incomplete ObservationsQ25938997
Mutations in residues of TP53 that directly contact DNA predict poor outcome in human primary breast cancerQ27851503
p53-dependent apoptosis modulates the cytotoxicity of anticancer agentsQ29615031
Cancer. p53, guardian of the genomeQ29615610
The relationship between prognostic and predictive factors in the management of breast cancerQ33538455
Structure and function of the p53 tumor suppressor gene: clues for rational cancer therapeutic strategiesQ34400583
Prognostic significance of TP53 alterations in breast carcinomaQ35976693
TP53 mutation analyses on breast carcinomas: a study of paraffin-embedded archival materialQ36135944
Mutation detection by highly sensitive methods indicates that p53 gene mutations in breast cancer can have important prognostic valueQ37730372
The molecular epidemiology of p53 gene mutations in human breast cancerQ41331238
William L. McGuire Memorial Symposium. The role and prognostic significance of p53 gene alterations in breast cancerQ43552305
Predicting response to cancer chemotherapy: the role of p53.Q45887109
Direct sequencing from touch preparations of human carcinomas: analysis of p53 mutations in breast carcinomasQ50802481
Pattern of p53 Gene Mutations in Breast Cancers of Women of the Midwestern United StatesQ52862568
Meeting highlights: International Consensus Panel on the Treatment of Primary Breast Cancer.Q53350484
p53 protein overexpression and chemosensitivity in breast cancer.Q54172779
Mutant p53 protein associated with chemosensitivity in breast cancer specimens.Q54189041
Dideoxy fingerprinting (ddF): A rapid and efficient screen for the presence of mutationsQ68170270
Prognostic significance of TP53 accumulation in human primary breast cancer: comparison between a rapid quantitative immunoassay and SSCP analysisQ71019316
Relationship between p53 gene abnormalities and other tumour characteristics in breast-cancer prognosisQ71019320
The p53 gene in breast cancer: prognostic value of complementary DNA sequencing versus immunohistochemistryQ71082995
Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patientsQ71169983
p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspectiveQ71191754
Loss of tumor marker-immunostaining intensity on stored paraffin slides of breast cancerQ71198612
Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapyQ71563602
p53 status and the efficacy of cancer therapy in vivoQ72839445
Detection of p53 gene mutation by rapid PCR-SSCP and its association with poor survival in breast cancerQ74013133
Prognosis and prediction of response in breast cancer: the current role of the main biological markersQ77683176
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)32-38
P577publication date2000-01-01
P1433published inInternational Journal of CancerQ332492
P1476titleA prospective trial of midwest breast cancer patients: a p53 gene mutation is the most important predictor of adverse outcome.
P478volume89

Reverse relations

cites work (P2860)
Q36442296A bioactive probe of the oxidative pentose phosphate cycle: novel strategy to reverse radioresistance in glucose deprived human colon cancer cells
Q52133539A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage.
Q40643483Comparison of p53 mutational status with mRNA and protein expression in a panel of 24 human breast carcinoma cell lines
Q47887299DNA repair and breast carcinoma susceptibility in women
Q46131826Detection of ultrarare somatic mutation in the human TP53 gene by bidirectional pyrophosphorolysis-activated polymerization allele-specific amplification
Q35132901Glucose deprivation increases nuclear DNA repair protein Ku and resistance to radiation induced oxidative stress in human cancer cells
Q36936952Immunohistochemistry and scoring of Ki-67 proliferative index and p53 expression in gastric B cell lymphoma from Northern African population: a pilot study
Q73443300Mutation analysis of p53 in ovarian tumors by DHPLC
Q36308536P53 immunohistochemical scoring: an independent prognostic marker for patients after hepatocellular carcinoma resection
Q24811790Perspectives on the chemical etiology of breast cancer
Q77397523Prognostic value of TP53 gene mutation in adjuvant treated breast cancer patients
Q24813658Proteomic identification of heat shock protein 90 as a candidate target for p53 mutation reactivation by PRIMA-1 in breast cancer cells
Q35810123Recent progress in predictive biomarkers for metastatic recurrence of human hepatocellular carcinoma: a review of the literature
Q37244111State of the art of neoadjuvant chemotherapy in breast cancer: rationale, results and recent developments
Q89727347TP53 Mutations and Outcomes in Breast Cancer: Reading beyond the Headlines
Q35078761TP53 and breast cancer
Q41236981The effect of immunohistochemically detected p53 accumulation in prognosis of breast cancer; A retrospective survey of outcome.
Q34668320The prognostic molecular markers in hepatocellular carcinoma
Q24617837Zeranol down-regulates p53 expression in primary cultured human breast cancer epithelial cells through epigenetic modification
Q34580735p53 as a mutagen test in breast cancer

Search more.