The Impact of the Epithelial-Mesenchymal Transition Regulator Hepatocyte Growth Factor Receptor/Met on Skin Immunity by Modulating Langerhans Cell Migration.

scientific article published on 16 March 2018

The Impact of the Epithelial-Mesenchymal Transition Regulator Hepatocyte Growth Factor Receptor/Met on Skin Immunity by Modulating Langerhans Cell Migration. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3389/FIMMU.2018.00517
P932PMC publication ID5864859
P698PubMed publication ID29616031

P2093author name stringThomas Hieronymus
Zsofia Sagi
P2860cites workInterplay between scatter factor receptors and B plexins controls invasive growthQ24295561
Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene ProductQ24310794
Activation of the zymogen of hepatocyte growth factor activator by thrombinQ24318554
The protein kinase complement of the human genomeQ24324497
Induction of antigen-specific regulatory T lymphocytes by human dendritic cells expressing the glucocorticoid-induced leucine zipperQ24678698
Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activationQ27320214
Epithelial-mesenchymal transitions in development and diseaseQ27860630
The semaphorin 4D receptor controls invasive growth by coupling with MetQ28219215
Contact allergens and epidermal proinflammatory cytokines modulate Langerhans cell E-cadherin expression in situQ71120773
Partial characterization of a hepatocyte growth factor from rat plateletsQ71327547
Enhancement of human hepatocyte growth factor production by interleukin-1 alpha and -1 beta and tumor necrosis factor-alpha by fibroblasts in cultureQ72075540
Hepatocyte growth factor is constitutively produced by human bone marrow stromal cells and indirectly promotes hematopoiesisQ73126057
Hepatocyte growth factor is a regulator of monocyte-macrophage functionQ73365858
Hepatocyte growth factor-stimulated invasiveness of monocytesQ73877053
The role of intravenous immunoglobulin therapy in mediating skin fibrosis in tight skin miceQ74455262
Expression and function of c-Met, a receptor for hepatocyte growth factor, during T-cell developmentQ74586546
Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skinQ77995830
Hepatocyte growth factor significantly suppresses collagen-induced arthritis in miceQ81386359
GILZ expression in human dendritic cells redirects their maturation and prevents antigen-specific T lymphocyte responseQ81491673
Attenuation of mouse acute colitis by naked hepatocyte growth factor gene transfer into the liverQ82556836
Dermal fibroblasts promote the migration of dendritic cellsQ84474126
β-Catenin promotes the differentiation of epidermal Langerhans dendritic cellsQ85883913
Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2Q86600568
Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cellsQ87551135
Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-β1-dependent human epidermal Langerhans cells.Q50623825
The hepatocyte growth factor (HGF)-MET receptor tyrosine kinase signaling pathway: Diverse roles in modulating immune cell functions.Q52886970
The role of SF/HGF and c-Met in the development of skeletal muscle.Q52980024
Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis.Q53357929
Cooperative interaction between alpha- and beta-chains of hepatocyte growth factor on c-Met receptor confers ligand-induced receptor tyrosine phosphorylation and multiple biological responses.Q53778646
Hepatocyte growth factor-induced c-Src-phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway inhibits dendritic cell activation by blocking IκB kinase activity.Q54593030
HGF/Met-Signaling Contributes to Immune Regulation by Modulating Tolerogenic and Motogenic Properties of Dendritic Cells.Q55009988
Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-MetQ58324027
Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized ratsQ60034429
Phorbol ester-induced secretion of human hepatocyte growth factor by human skin fibroblasts and its inhibition by dexamethasoneQ67593759
Hepatocyte growth factor is a synergistic factor for the growth of hematopoietic progenitor cellsQ67919319
Expression of gp40, the murine homologue of human epithelial cell adhesion molecule (Ep-CAM), by murine dendritic cellsQ70911182
Met, metastasis, motility and moreQ28235183
Invasive growth: a MET-driven genetic programme for cancer and stem cellsQ28253680
Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factorQ28307227
Differential responsiveness of cord and adult blood monocytes to hepatocyte growth factorQ28347515
The role of hepatocyte growth factor and its receptor c-met in interactions between lymphocytes and stromal cells in secondary human lymphoid organsQ28363959
Scatter factor/hepatocyte growth factor is essential for liver developmentQ28504542
Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb budQ28506228
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?Q29547559
Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin IIQ30498266
Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivoQ30513354
Serial analysis of gene expression in human monocyte-derived dendritic cellsQ30741965
Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: cloning of its cDNA, purification and characterization of recombinant proteinQ33324580
External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriersQ33590480
Hepatocyte growth factor inhibits CNS autoimmunity by inducing tolerogenic dendritic cells and CD25+Foxp3+ regulatory T cellsQ33778883
Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor bindingQ33938013
Regulatory activity of autocrine IL-10 on dendritic cell functionsQ33938563
Functional map and domain structure of MET, the product of the c- met protooncogene and receptor for hepatocyte growth factor/scatter factorQ34267718
Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator.Q34379859
Boolean approach to signalling pathway modelling in HGF-induced keratinocyte migrationQ34409663
Scatter-factor and semaphorin receptors: cell signalling for invasive growthQ34632043
Showering c-MET-dependent cancers with drugsQ34769397
Drug development of MET inhibitors: targeting oncogene addiction and expedienceQ34782774
Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) functionQ34963286
How to make tubes: signaling by the Met receptor tyrosine kinaseQ35147372
A novel role for Bruton's tyrosine kinase in hepatocyte growth factor-mediated immunoregulation of dendritic cellsQ35213426
Hepatocyte growth factor prevents lupus nephritis in a murine lupus model of chronic graft-versus-host diseaseQ35605610
Hepatocyte growth factor ameliorates dermal sclerosis in the tight-skin mouse model of sclerodermaQ35630012
CD44 is required for two consecutive steps in HGF/c-Met signaling.Q35805198
Autocrine/paracrine TGF-β1 inhibits Langerhans cell migrationQ36069078
MET is required for the recruitment of anti-tumoural neutrophilsQ36125652
The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesisQ36235637
PGE2-induced metalloproteinase-9 is essential for dendritic cell migrationQ36384618
New signals from the invasive frontQ36488744
Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP)Q36704207
Structural and functional characterization of the mouse hepatocyte growth factor gene promoter.Q36762650
Met provides essential signals for liver regenerationQ36987592
Hepatocyte growth factor activator (HGFA): pathophysiological functions in vivoQ37733681
MET signalling: principles and functions in development, organ regeneration and cancerQ37811895
Hepatocyte growth factor twenty years on: Much more than a growth factorQ37825664
Targeting MET in cancer: rationale and progressQ37978193
Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAsQ38083976
The clash of Langerhans cell homeostasis in skin: Should I stay or should I go?Q38194815
Mechanisms regulating skin immunity and inflammationQ38203783
Hepatocyte growth factor: A regulator of inflammation and autoimmunityQ38283419
Hepatocyte growth factor and Met in drug discoveryQ38377273
Antigen-Presenting Cells in the SkinQ39146789
c-Met is essential for wound healing in the skinQ39735911
Hepatocyte growth factor differently influences Met-E-cadherin phosphorylation and downstream signaling pathway in two models of breast cellsQ40243630
c-Met and its ligand hepatocyte growth factor/scatter factor regulate mature B cell survival in a pathway induced by CD74.Q40472507
A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growthQ40765252
Emerging multipotent aspects of hepatocyte growth factorQ41066829
Hepatocyte growth factor specifically binds to sulfoglycolipidsQ41476038
Regulation of release of hepatocyte growth factor from human promyelocytic leukemia cells, HL-60, by 1,25-dihydroxyvitamin D3, 12-O-tetradecanoylphorbol 13-acetate, and dibutyryl cyclic adenosine monophosphate.Q41543722
Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherinQ41578917
TGF-beta is a potent inhibitor of hepatocyte growth factor secretion by human fibroblastsQ41605256
Paracrine regulation of germinal center B cell adhesion through the c-met-hepatocyte growth factor/scatter factor pathwayQ41903686
The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing.Q42028035
Scatter factor is a fibroblast-derived modulator of epithelial cell mobilityQ42807925
The impact of c-met/scatter factor receptor on dendritic cell migrationQ44062597
The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity.Q44274081
Autocrine production of biologically active hepatocyte growth factor (HGF) by injured human skin.Q44459039
Ameliorating effect of hepatocyte growth factor on inflammatory bowel disease in a murine modelQ45154742
Up-regulation of hepatocyte growth factor gene expression by interleukin-1 in human skin fibroblastsQ45164797
Molecular cloning of a new transforming gene from a chemically transformed human cell line.Q45345810
Dendritic cell function in mice lacking Plexin C1.Q46557692
A novel role of hepatocyte growth factor as an immune regulator through suppressing dendritic cell functionQ47724235
Identification of a novel population of highly cytotoxic c-Met-expressing CD8+ T lymphocytes.Q48334272
Langerhans cells and lymph node dendritic cells express the tight junction component claudin-1.Q48910439
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectcellQ7868
growth factor receptorQ118226
membrane proteinQ423042
integumentary systemQ483213
enzymeQ8047
cell surface receptorQ2476074
proto-oncogene proteinQ66020913
neoplasm proteinQ66894191
hemic and immune systemsQ70202933
P304page(s)517
P577publication date2018-03-16
P1433published inFrontiers in ImmunologyQ27723748
P1476titleThe Impact of the Epithelial-Mesenchymal Transition Regulator Hepatocyte Growth Factor Receptor/Met on Skin Immunity by Modulating Langerhans Cell Migration.
P478volume9

Reverse relations

cites work (P2860)
Q60920855HGF/c-MET Signaling in Melanocytes and Melanoma
Q92344290Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy
Q91997148c-Met as a new marker of cellular senescence

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