HSP70 protects rats and hippocampal neurons from central nervous system oxygen toxicity by suppression of NO production and NF-κB activation.

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HSP70 protects rats and hippocampal neurons from central nervous system oxygen toxicity by suppression of NO production and NF-κB activation. is …
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scholarly articleQ13442814

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P356DOI10.1177/1535370218773982
P932PMC publication ID5956664
P698PubMed publication ID29763367

P2093author name stringKun Zhang
Shulin Liu
Weigang Xu
Guoyang Huang
Hongjie Yi
P2860cites workGeranylgeranylacetone, a noninvasive heat shock protein inducer, induces protein kinase C and leads to neuroprotection against cerebral infarction in ratsQ46889493
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Heat acclimation prolongs the time to central nervous system oxygen toxicity in the rat. Possible involvement of HSP72.Q48402827
Perfluorocarbon-facilitated CNS oxygen toxicity in rats: reversal by edaravoneQ48445689
Hsp70 and Hsp40 improve neurite outgrowth and suppress intracytoplasmic aggregate formation in cultured neuronal cells expressing mutant SOD1.Q48493107
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Heat shock protein 70 suppresses astroglial-inducible nitric-oxide synthase expression by decreasing NFkappaB activationQ48960660
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Heat shock protein 70 protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus via inhibition of nuclear factor-κB activation-induced nitric oxide synthase II expressionQ38311817
Preinduction of heat shock protein 70 protects mice against post-infection irritable bowel syndrome via NF-κB and NOS/NO signaling pathwaysQ41087764
Interplay between the kinin B1 receptor and inducible nitric oxide synthase in insulin resistanceQ41912702
Oxygen breathing accelerates decompression from saturation at 40 msw in 70-kg swineQ41987426
Exogenous protein Hsp70/Hsc70 can penetrate into brain structures and attenuate the severity of chemically-induced seizures.Q42910865
Cox-2 inhibition can lead to adverse effects in a rat model for temporal lobe epilepsyQ42965558
EFfect of quercetin on the severity of chemically induced seizures and the content of heat shock protein 70 in the rat brain structuresQ43035609
Effect of geranylgeranylaceton on cellular damage induced by proteasome inhibition in cultured spinal neuronsQ44069119
Contributions of Endothelial and Neuronal Nitric Oxide Synthases to Cerebrovascular Responses to HyperoxiaQ44606748
Astroglial activation accompanies heat shock protein upregulation in rat brain following single oral dose of geranylgeranylacetoneQ44630213
Overexpression of rat heat shock protein 70 reduces neuronal injury after transient focal ischemia, transient global ischemia, or kainic acid-induced seizuresQ44633150
Attenuation of cerebral oxygen toxicity by sound conditioningQ44799962
A single oral dose of geranylgeranylacetone attenuates kainic acid-induced seizures and neuronal cell death in rat hippocampusQ45040746
Repetitive hyperbaric oxygen exposures enhance sensitivity to convulsion by upregulation of eNOS and nNOS.Q46701039
P433issue9
P921main subjectNF-κBQ411114
P304page(s)770-779
P577publication date2018-05-01
P1433published inExperimental Biology and MedicineQ15716535
P1476titleHSP70 protects rats and hippocampal neurons from central nervous system oxygen toxicity by suppression of NO production and NF-κB activation.
P478volume243

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