| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/NRMICRO2452 |
| P953 | full work available at URL | https://europepmc.org/articles/PMC7096814 |
| https://www.nature.com/articles/nrmicro2452.pdf | ||
| https://europepmc.org/articles/PMC7096814?pdf=render | ||
| http://www.nature.com/articles/nrmicro2452 | ||
| http://www.nature.com/articles/nrmicro2452.pdf | ||
| P932 | PMC publication ID | 7096814 |
| P698 | PubMed publication ID | 21060318 |
| P2093 | author name string | Anatoly P. Gmyl | |
| Vadim I. Agol | |||
| P2860 | cites work | CD4+ T cells are important for clearance of DA strain of TMEV from the central nervous system of SJL/J mice | Q80357716 |
| 2Apro is a multifunctional protein that regulates the stability, translation and replication of poliovirus RNA | Q81504469 | ||
| A second virus-encoded proteinase involved in proteolytic processing of poliovirus polyprotein. | Q42028125 | ||
| Euprosterna elaeasa virus genome sequence and evolution of the Tetraviridae family: emergence of bipartite genomes and conservation of the VPg signal with the dsRNA Birnaviridae family | Q42641517 | ||
| A picornaviral protein synthesized out of frame with the polyprotein plays a key role in a virus-induced immune-mediated demyelinating disease. | Q42677791 | ||
| Aichi virus 2A protein is involved in viral RNA replication | Q42758555 | ||
| RNA nuclear export is blocked by poliovirus 2A protease and is concomitant with nucleoporin cleavage. | Q43269551 | ||
| Purification of two picornaviral 2A proteinases: interaction with eIF-4 gamma and influence on in vitro translation | Q43677793 | ||
| Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence | Q43729049 | ||
| Leader protein of encephalomyocarditis virus binds zinc, is phosphorylated during viral infection, and affects the efficiency of genome translation | Q43908617 | ||
| Infection with enterovirus 71 or expression of its 2A protease induces apoptotic cell death | Q44005273 | ||
| Virus-specific proteins associated with ribosomes of Krebs-II cells infected with encephalomyocarditis virus | Q44483124 | ||
| Putative papain-related thiol proteases of positive-strand RNA viruses. Identification of rubi- and aphthovirus proteases and delineation of a novel conserved domain associated with proteases of rubi-, alpha- and coronaviruses | Q44808922 | ||
| Molecular analysis of duck hepatitis virus type 1. | Q45407197 | ||
| Inhibition of cap-dependent gene expression induced by protein 2A of hepatitis A virus | Q45743087 | ||
| Intrinsic signals for the assembly of hepatitis A virus particles. Role of structural proteins VP4 and 2A. | Q45751258 | ||
| A Theiler's virus alternatively initiated protein inhibits the generation of H-2K-restricted virus-specific cytotoxicity. | Q45751802 | ||
| The two species of the foot-and-mouth disease virus leader protein, expressed individually, exhibit the same activities | Q45775389 | ||
| Identification and site-directed mutagenesis of the primary (2A/2B) cleavage site of the hepatitis A virus polyprotein: functional impact on the infectivity of HAV RNA transcripts | Q45790633 | ||
| Translational barrier in central region of encephalomyocarditis virus genome. Modulation by elongation factor 2 (eEF-2). | Q45798457 | ||
| The position of polypeptide G on the encephalomyocarditis virus polyprotein cleavage map | Q45798763 | ||
| Leader polypeptides encoded in the 5′‐region of the encephalomyocarditis virus genome | Q45800173 | ||
| Genomic features and evolutionary constraints in Saffold-like cardioviruses | Q48066084 | ||
| Protein Identification and Analysis Tools on the ExPASy Server | Q56880448 | ||
| The mengovirus leader protein blocks interferon-α/β gene transcription and inhibits activation of interferon regulatory factor 3 | Q57206555 | ||
| Proteolytic Cleavage of the p65-RelA Subunit of NF-κB during Poliovirus Infection | Q58664420 | ||
| Persistent Yeast Single-stranded RNA Viruses Existin Vivoas Genomic RNA·RNA Polymerase Complexes in 1:1 Stoichiometry | Q60321615 | ||
| Studies on dicistronic polioviruses implicate viral proteinase 2Apro in RNA replication | Q70475203 | ||
| The cleavage activities of aphthovirus and cardiovirus 2A proteins | Q73016795 | ||
| The 2A proteins of three diverse picornaviruses are related to each other and to the H-rev107 family of proteins involved in the control of cell proliferation | Q73367812 | ||
| 2A proteinase of human rhinovirus cleaves cytokeratin 8 in infected HeLa cells | Q73924380 | ||
| Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications | Q24647040 | ||
| CDD: specific functional annotation with the Conserved Domain Database | Q24655481 | ||
| Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor | Q27478302 | ||
| A highly prevalent and genetically diversified Picornaviridae genus in South Asian children | Q27487762 | ||
| NS1' of Flaviviruses in the Japanese Encephalitis Virus Serogroup Is a Product of Ribosomal Frameshifting and Plays a Role in Viral Neuroinvasiveness | Q27490848 | ||
| NMR structure of the mengovirus Leader protein zinc-finger domain | Q27649901 | ||
| Clustal W and Clustal X version 2.0 | Q27860517 | ||
| Equine rhinovirus serotypes 1 and 2: relationship to each other and to aphthoviruses and cardioviruses | Q28287190 | ||
| Divergent picornavirus IRES elements | Q28289591 | ||
| Proteinase 2Apro Is Essential for Enterovirus Replication in Type I Interferon-Treated Cells | Q29039070 | ||
| A conserved domain in the leader proteinase of foot-and-mouth disease virus is required for proper subcellular localization and function. | Q30373675 | ||
| Encephalomyocarditis viral protein 2A localizes to nucleoli and inhibits cap-dependent mRNA translation | Q30732093 | ||
| Genomic evidence that simian virus 2 and six other simian picornaviruses represent a new genus in Picornaviridae | Q30881302 | ||
| A highly divergent picornavirus in a marine mammal | Q31133378 | ||
| The C-terminal residues of poliovirus proteinase 2A(pro) are critical for viral RNA replication but not for cis- or trans-proteolytic cleavage | Q31846292 | ||
| Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the MHC class I pathway | Q33510911 | ||
| Influence of the Theiler's virus L* protein on macrophage infection, viral persistence, and neurovirulence | Q33604509 | ||
| Theiler's murine encephalomyelitis virus L* amino acid position 93 is important for virus persistence and virus-induced demyelination | Q33614386 | ||
| Cleavage of Poly(A)-binding protein by coxsackievirus 2A protease in vitro and in vivo: another mechanism for host protein synthesis shutoff? | Q33639744 | ||
| Cleavage of poly(A)-binding protein by enterovirus proteases concurrent with inhibition of translation in vitro. | Q33639759 | ||
| L* protein of the DA strain of Theiler's murine encephalomyelitis virus is important for virus growth in a murine macrophage-like cell line. | Q33784171 | ||
| A protein critical for a Theiler's virus-induced immune system-mediated demyelinating disease has a cell type-specific antiapoptotic effect and a key role in virus persistence | Q33785219 | ||
| Rapamycin and wortmannin enhance replication of a defective encephalomyocarditis virus | Q33785626 | ||
| Inhibition of L-deleted foot-and-mouth disease virus replication by alpha/beta interferon involves double-stranded RNA-dependent protein kinase | Q33841904 | ||
| Poliovirus protein 3A inhibits tumor necrosis factor (TNF)-induced apoptosis by eliminating the TNF receptor from the cell surface | Q33848147 | ||
| An attenuating mutation in the 2A protease of swine vesicular disease virus, a picornavirus, regulates cap- and internal ribosome entry site-dependent protein synthesis. | Q33848688 | ||
| The leader protein of Theiler's virus inhibits immediate-early alpha/beta interferon production | Q33853304 | ||
| Enteroviral protease 2A cleaves dystrophin: evidence of cytoskeletal disruption in an acquired cardiomyopathy. | Q33855715 | ||
| 2A protease is not a prerequisite for poliovirus replication | Q33877439 | ||
| Picornavirales, a proposed order of positive-sense single-stranded RNA viruses with a pseudo-T = 3 virion architecture | Q34010064 | ||
| Mechanisms of severe acute respiratory syndrome pathogenesis and innate immunomodulation | Q34014960 | ||
| Proteolytic cleavage of the catalytic subunit of DNA-dependent protein kinase during poliovirus infection | Q34186037 | ||
| Encephalomyocarditis virus (EMCV) proteins 2A and 3BCD localize to nuclei and inhibit cellular mRNA transcription but not rRNA transcription | Q34223097 | ||
| Role of nonstructural proteins 3A and 3B in host range and pathogenicity of foot-and-mouth disease virus. | Q34227219 | ||
| Analysis of deletion mutants indicates that the 2A polypeptide of hepatitis A virus participates in virion morphogenesis | Q34343028 | ||
| The leader proteinase of foot-and-mouth disease virus inhibits the induction of beta interferon mRNA and blocks the host innate immune response | Q34353443 | ||
| Molecular analysis of three Ljungan virus isolates reveals a new, close-to-root lineage of the Picornaviridae with a cluster of two unrelated 2A proteins | Q34363105 | ||
| Nucleocytoplasmic traffic disorder induced by cardioviruses. | Q34434945 | ||
| Site-specific release of nascent chains from ribosomes at a sense codon | Q34591493 | ||
| Coxsackievirus B3 proteases 2A and 3C induce apoptotic cell death through mitochondrial injury and cleavage of eIF4GI but not DAP5/p97/NAT1. | Q34595959 | ||
| Complete genome sequence analysis of Seneca Valley virus-001, a novel oncolytic picornavirus | Q34771137 | ||
| The Big Bang of picorna-like virus evolution antedates the radiation of eukaryotic supergroups | Q34876613 | ||
| Cleavage of IPS-1 in cells infected with human rhinovirus. | Q35001899 | ||
| A picornavirus protein interacts with Ran-GTPase and disrupts nucleocytoplasmic transport | Q35033719 | ||
| Involvement of cardiovirus leader in host cell-restricted virus expression | Q35074671 | ||
| Inhibition of U snRNP assembly by a virus-encoded proteinase | Q35758087 | ||
| A case for "StopGo": reprogramming translation to augment codon meaning of GGN by promoting unconventional termination (Stop) after addition of glycine and then allowing continued translation (Go) | Q35794700 | ||
| The leader polypeptide of Theiler's virus is essential for neurovirulence but not for virus growth in BHK cells | Q35845796 | ||
| Hepatitis A viruses with deletions in the 2A gene are infectious in cultured cells and marmosets | Q35845842 | ||
| The leader peptide of Theiler's murine encephalomyelitis virus is a zinc-binding protein | Q35852746 | ||
| Poliovirus-encoded protease 2APro cleaves the TATA-binding protein but does not inhibit host cell RNA polymerase II transcription in vitro. | Q35892236 | ||
| RNA replication without RNA-dependent RNA polymerase: surprises from hepatitis delta virus | Q36163276 | ||
| Cardiovirus 2A protein associates with 40S but not 80S ribosome subunits during infection | Q36315741 | ||
| Degradation of nuclear factor kappa B during foot-and-mouth disease virus infection | Q36315811 | ||
| Differential targeting of nuclear pore complex proteins in poliovirus-infected cells | Q36483353 | ||
| Giardiavirus double-stranded RNA genome encodes a capsid polypeptide and a gag-pol-like fusion protein by a translation frameshift | Q36541228 | ||
| Protein 2A is not required for Theiler's virus replication | Q36549022 | ||
| Replication of poliovirus RNA and subgenomic RNA transcripts in transfected cells | Q36685098 | ||
| Alternative translation initiation site in the DA strain of Theiler's murine encephalomyelitis virus | Q36696184 | ||
| Leader protein of foot-and-mouth disease virus is required for cleavage of the p220 component of the cap-binding protein complex | Q36882880 | ||
| Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220. | Q36918487 | ||
| Poliovirus mutant that does not selectively inhibit host cell protein synthesis | Q36950831 | ||
| Inhibition of mRNA export and dimerization of interferon regulatory factor 3 by Theiler's virus leader protein | Q37077303 | ||
| Leader-induced phosphorylation of nucleoporins correlates with nuclear trafficking inhibition by cardioviruses | Q37099800 | ||
| Mengovirus-induced rearrangement of the nuclear pore complex: hijacking cellular phosphorylation machinery | Q37127856 | ||
| Evading the host immune response: how foot-and-mouth disease virus has become an effective pathogen | Q37133366 | ||
| RIG-I is cleaved during picornavirus infection | Q37344605 | ||
| Bidirectional increase in permeability of nuclear envelope upon poliovirus infection and accompanying alterations of nuclear pores. | Q37492721 | ||
| Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A | Q37694671 | ||
| NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase | Q39195523 | ||
| Poliovirus 2A protease induces apoptotic cell death | Q39451010 | ||
| Ability of foot-and-mouth disease virus to form plaques in cell culture is associated with suppression of alpha/beta interferon. | Q39596912 | ||
| The mengovirus leader protein suppresses alpha/beta interferon production by inhibition of the iron/ferritin-mediated activation of NF-kappa B. | Q39684727 | ||
| Differential IFN-alpha/beta production suppressing capacities of the leader proteins of mengovirus and foot-and-mouth disease virus. | Q39782470 | ||
| Bypass suppression of small-plaque phenotypes by a mutation in poliovirus 2A that enhances apoptosis | Q39822136 | ||
| Antiapoptotic activity of the cardiovirus leader protein, a viral "security" protein | Q39855956 | ||
| Theiler's murine encephalomyelitis virus leader protein is the only nonstructural protein tested that induces apoptosis when transfected into mammalian cells | Q39858745 | ||
| Foot-and-mouth disease virus Lb proteinase can stimulate rhinovirus and enterovirus IRES-driven translation and cleave several proteins of cellular and viral origin. | Q39870268 | ||
| The foot-and-mouth disease virus leader proteinase gene is not required for viral replication | Q39871495 | ||
| Mengovirus leader is involved in the inhibition of host cell protein synthesis | Q39875408 | ||
| Pathogenesis of wild-type and leaderless foot-and-mouth disease virus in cattle | Q39875702 | ||
| The unique role of domain 2A of the hepatitis A virus precursor polypeptide P1-2A in viral morphogenesis | Q39934704 | ||
| Early phosphatidylinositol 3-kinase/Akt pathway activation limits poliovirus-induced JNK-mediated cell death | Q40021213 | ||
| Morphogenesis of hepatitis A virus: isolation and characterization of subviral particles | Q40104711 | ||
| A second protease of foot-and-mouth disease virus. | Q40126769 | ||
| RNA-binding properties of nonstructural polypeptide G of encephalomyocarditis virus | Q40163157 | ||
| Intracellular localization and effects of individually expressed human parechovirus 1 non-structural proteins | Q40166098 | ||
| Cardiovirus leader proteins are functionally interchangeable and have evolved to adapt to virus replication fitness | Q40294352 | ||
| Structure of the FMDV translation initiation site and of the structural proteins | Q40494648 | ||
| The leader protein of Theiler's virus interferes with nucleocytoplasmic trafficking of cellular proteins | Q40572718 | ||
| Conservation of L and 3C proteinase activities across distantly related aphthoviruses. | Q40685584 | ||
| Coding changes in the poliovirus protease 2A compensate for 5'NCR domain V disruptions in a cell-specific manner | Q40831803 | ||
| Sequence analysis of a porcine enterovirus serotype 1 isolate: relationships with other picornaviruses | Q40932531 | ||
| Occurrence, function and evolutionary origins of '2A-like' sequences in virus genomes | Q41039835 | ||
| The C-terminal domain of eukaryotic protein synthesis initiation factor (eIF) 4G is sufficient to support cap-independent translation in the absence of eIF4E. | Q41064255 | ||
| Genetic analysis of mengovirus protein 2A: its function in polyprotein processing and virus reproduction | Q41065910 | ||
| Construction of a chimeric Theiler's murine encephalomyelitis virus containing the leader gene of foot-and-mouth disease virus | Q41149463 | ||
| The effect of poliovirus proteinase 2Apro expression on cellular metabolism. Inhibition of DNA replication, RNA polymerase II transcription, and translation | Q41670238 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 867-878 | |
| P577 | publication date | 2010-11-09 | |
| P1433 | published in | Nature Reviews Microbiology | Q1071797 |
| P1476 | title | Viral security proteins: counteracting host defences | |
| P478 | volume | 8 |
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| Q34208753 | Computational analysis of two species C human adenoviruses provides evidence of a novel virus |
| Q38052688 | Cytopathic effects: virus-modulated manifestations of innate immunity? |
| Q33761818 | Differential restriction patterns of mRNA decay factor AUF1 during picornavirus infections. |
| Q52655516 | Emergency Services of Viral RNAs: Repair and Remodeling. |
| Q28744244 | Encephalomyocarditis virus 2A protein is required for viral pathogenesis and inhibition of apoptosis |
| Q34697319 | Enterovirus infections of the central nervous system |
| Q92340057 | Essential Role of Enterovirus 2A Protease in Counteracting Stress Granule Formation and the Induction of Type I Interferon |
| Q21089595 | Evidence for novel hepaciviruses in rodents |
| Q39430496 | Evolution of poliovirus defective interfering particles expressing Gaussia luciferase |
| Q52806096 | Evolutionary Origins of Enteric Hepatitis Viruses. |
| Q58598695 | FMDV leader protease cleaves G3BP1 and G3BP2 and inhibits stress granule formation |
| Q39390919 | Gemin5 proteolysis reveals a novel motif to identify L protease targets |
| Q31060253 | High-performance integrated virtual environment (HIVE): a robust infrastructure for next-generation sequence data analysis. |
| Q34712064 | Identification of residues of SARS-CoV nsp1 that differentially affect inhibition of gene expression and antiviral signaling |
| Q35212982 | Immunity, suicide or both? Ecological determinants for the combined evolution of anti-pathogen defense systems |
| Q91030550 | In pursuit of intriguing puzzles |
| Q38236277 | Induction and suppression of innate antiviral responses by picornaviruses |
| Q42254652 | Infection of human islets of Langerhans with two strains of Coxsackie B virus serotype 1: assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity pathway |
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