Combined methylation of p16 and hMLH1 (CMETH2) discriminates a subpopulation with better prognosis in colorectal cancer patients with microsatellite instability tumors.

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Combined methylation of p16 and hMLH1 (CMETH2) discriminates a subpopulation with better prognosis in colorectal cancer patients with microsatellite instability tumors. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S13277-014-3027-1
P698PubMed publication ID25576161
P5875ResearchGate publication ID270597103

P50authorEduardo Díaz-RubioQ41345398
Silvia VeganzonesQ54297886
Marta VidaurretaQ54297907
Virginia De La Orden GarciaQ80826450
P2093author name stringM L Maestro
J Cerdán
S Rafael
B Mediero
M Espantaleón
P2860cites workPromoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomasQ24603535
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CpG island methylator phenotype is an independent predictor of survival benefit from 5-fluorouracil in stage III colorectal cancerQ44545555
Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancerQ45141920
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p16 gene methylation in colorectal cancer patients with long-term follow-up.Q53177600
Characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers.Q53302100
Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomasQ53373414
DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancersQ53402717
Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinomaQ53603188
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CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels.Q54797906
Adverse Prognostic Effect of Methylation in Colorectal Cancer Is Reversed by Microsatellite InstabilityQ56589885
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p16 Gene Methylation in Colorectal Tumors: Correlation with Clinicopathological Features and Prognostic ValueQ58371730
Oncosuppressor methylation: A possible key role in colon metastatic progressionQ60170548
Poor Survival Associated with theBRAFV600E Mutation in Microsatellite-Stable Colon CancersQ60673656
Subsets of microsatellite-unstable colorectal cancers exhibit discordance between the CpG island methylator phenotype and MLH1 methylation statusQ61865595
Association between CpG island methylation and microsatellite instability in colorectal cancerQ73622839
CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinomaQ79988265
APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancerQ80278776
Colon cancer: it's CIN or CIMPQ82175754
Aberrant p16((INK4a)) methylation is a frequent event in colorectal cancers: prognostic value and relation to mRNA expression and immunoreactivityQ84586357
Molecular pathways and pathomorphology of colorectal cancersQ84890225
P433issue5
P921main subjectcolorectal cancerQ188874
P304page(s)3853-3861
P577publication date2015-01-10
P1433published inTumor BiologyQ15757842
P1476titleCombined methylation of p16 and hMLH1 (CMETH2) discriminates a subpopulation with better prognosis in colorectal cancer patients with microsatellite instability tumors
P478volume36

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cites work (P2860)
Q26739706Implications of Genetic and Epigenetic Alterations of CDKN2A (p16(INK4a)) in Cancer
Q52802632Prognostic DNA methylation markers for sporadic colorectal cancer: a systematic review
Q33598672Prognostic value of MLH1 promoter methylation in male patients with esophageal squamous cell carcinoma
Q38637642The role of cell-free DNA in predicting colorectal cancer prognosis

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