The connexin mimetic peptide Gap27 increases human dermal fibroblast migration in hyperglycemic and hyperinsulinemic conditions in vitro.

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The connexin mimetic peptide Gap27 increases human dermal fibroblast migration in hyperglycemic and hyperinsulinemic conditions in vitro. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JCP.22705
P698PubMed publication ID21984074
P5875ResearchGate publication ID51703629

P2093author name stringJohanna M Brandner
Patricia E M Martin
Catherine S Wright
Simone Pollok
David J Flint
P2860cites workEndothelium-dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis?Q24672135
Quantitative real-time RT-PCR data analysis: current concepts and the novel "gene expression's CT difference" formulaQ28263575
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Enhanced connexin 43 expression delays intra-mitotic duration and cell cycle traverse independently of gap junction channel functionQ30433411
Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1.Q33419704
A gene signature for post-infectious chronic fatigue syndromeQ33474566
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Connexin mimetic peptides: specific inhibitors of gap-junctional intercellular communicationQ34332523
Matrix metalloproteinase inhibitor GM 6001 attenuates keratinocyte migration, contraction and myofibroblast formation in skin woundsQ34346010
Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repairQ34437758
Wounding alters epidermal connexin expression and gap junction-mediated intercellular communicationQ34452878
Abnormal connexin expression underlies delayed wound healing in diabetic skin.Q34667089
The molecular biology of chronic wounds and delayed healing in diabetesQ36499284
The gap junction cellular internet: connexin hemichannels enter the signalling limelightQ36500579
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Mimetic peptides as blockers of connexin channel-facilitated intercellular communicationQ37130229
Connexons and cell adhesion: a romantic phaseQ37164105
Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesisQ37169609
Connexin43 carboxyl-terminal peptides reduce scar progenitor and promote regenerative healing following skin wounding.Q37287565
Role of Ndt80p in sterol metabolism regulation and azole resistance in Candida albicans.Q37301928
Pannexins, distant relatives of the connexin family with specific cellular functions?Q37567592
Wound repair at a glanceQ37591028
LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue growth factorQ38355075
Peptidoglycan derived from Staphylococcus epidermidis induces Connexin43 hemichannel activity with consequences on the innate immune response in endothelial cellsQ39659848
Maturational alterations in gap junction expression and associated collagen synthesis in response to tendon functionQ39886983
Adhesive properties of connexin hemichannelsQ39958082
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Differential gene expression in migrating renal epithelial cells after woundingQ41266947
Altered connexin expression and wound healing in the epidermis of connexin-deficient miceQ42444130
A murine living skin equivalent amenable to live-cell imaging: analysis of the roles of connexins in the epidermisQ42520745
Akt blockade downregulates collagen and upregulates MMP1 in human dermal fibroblastsQ42525511
Gene expression profiling reveals new protective roles for vitamin C in human skin cellsQ42810126
Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration.Q42832944
3-Deoxyglucosone-collagen alters human dermal fibroblast migration and adhesion: implications for impaired wound healing in patients with diabetesQ43273507
Up-regulated type I collagen expression by the inhibition of Rac1 signaling pathway in human dermal fibroblastsQ44220069
Connexin channels, connexin mimetic peptides and ATP releaseQ44697300
Hyperglycaemic conditions hamper keratinocyte locomotion via sequential inhibition of distinct pathways: new insights on poor wound closure in patients with diabetesQ46082858
Expression of intracellular filament, collagen, and collagenase genes in diabetic and normal skin after injuryQ46126451
Gap junction adhesion is necessary for radial migration in the neocortexQ46320394
Profiling motility signal-specific genes in primary human keratinocytesQ46680516
Connexins 26, 30, and 43: differences among spontaneous, chronic, and accelerated human wound healingQ47613086
Keratinocyte-releasable factors increased the expression of MMP1 and MMP3 in co-cultured fibroblasts under both 2D and 3D culture conditions.Q47815533
Connexin mimetic peptides improve cell migration rates of human epidermal keratinocytes and dermal fibroblasts in vitro.Q51751372
Targeting connexin43 expression accelerates the rate of wound repair.Q52099637
Recombinant connective tissue growth factor modulates porcine skin fibroblast gene expression.Q54772887
P433issue1
P921main subjecthyperglycemiaQ271993
dermal fibroblastQ5262669
P304page(s)77-87
P577publication date2011-02-24
P1433published inJournal of Cellular PhysiologyQ1524270
P1476titleThe connexin mimetic peptide Gap27 increases human dermal fibroblast migration in hyperglycemic and hyperinsulinemic conditions in vitro.
P478volume227

Reverse relations

cites work (P2860)
Q43979703Cell motility in models of wounded human skin is improved by Gap27 despite raised glucose, insulin and IGFBP-5.
Q42621111Connexin 43 Hemichannels Regulate the Expression of Wound Healing-Associated Genes in Human Gingival Fibroblasts
Q89314669Connexin 43 Plays a Role in Pulmonary Vascular Reactivity in Mice
Q35668477Connexin 43 deficiency accelerates skin wound healing and extracellular matrix remodeling in mice.
Q97521685Connexin 43 plays a role in proliferation and migration of pulmonary arterial fibroblasts in response to hypoxia
Q88215936Connexin 43 regulates the expression of wound healing-related genes in human gingival and skin fibroblasts
Q55316335Connexin Communication Compartments and Wound Repair in Epithelial Tissue.
Q38502103Connexin43 plays diverse roles in co-ordinating cell migration and wound closure events
Q38532374Connexins and pannexins in the integumentary system: the skin and appendages
Q38330396Connexins and skin disease: insights into the role of beta connexins in skin homeostasis.
Q38194341Connexins: sensors of epidermal integrity that are therapeutic targets
Q39340613Differential susceptibility of Cx26 mutations associated with epidermal dysplasias to peptidoglycan derived from Staphylococcus aureus and Staphylococcus epidermidis.
Q37320992Effect of connexin 43 inhibition by the mimetic peptide Gap27 on corneal wound healing, inflammation and neovascularization.
Q37419850Embryonic wound healing: a primer for engineering novel therapies for tissue repair
Q35542173Expression and function of connexin 43 in human gingival wound healing and fibroblasts
Q38034066Manipulating connexin communication channels: use of peptidomimetics and the translational outputs
Q38263990Mind the gap: connexins and cell-cell communication in the diabetic kidney.
Q46278001Novel role of zonula occludens-1: A tight junction protein closely associated with the odontoblast differentiation of human dental pulp cells
Q42797642Overexpression of the gap junction protein Cx43 as found in diabetic foot ulcers can retard fibroblast migration.
Q36174730Porokeratotic eccrine nevus may be caused by somatic connexin26 mutations.
Q91004438Regulation of connexin 43 expression in human gingival fibroblasts
Q52354401Role of Non-Myocyte Gap Junctions and Connexin Hemichannels in Cardiovascular Health and Disease: Novel Therapeutic Targets?
Q49804036The Connexin Mimetic Peptide Gap27 and Cx43-Knockdown Reveal Differential Roles for Connexin43 in Wound Closure Events in Skin Model Systems

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